Joanne P. Young

发表

Characterisation of a subtype of colorectal cancer combining features of the suppressor and mild mutator pathways.

B. Leggett, M. Cummings, L. Simms, 1999, Journal of clinical pathology.

Role of inherited defects of MYH in the development of sporadic colorectal cancer

N. Matsubara, B. Leggett, J. Jass, 2004, Genes, chromosomes & cancer.

Mutation of hMSH3 and hMSH6 mismatch repair genes in genetically unstable human colorectal and gastric carcinomas

S. Powell, Suna Wang, D. Kong, 1997, Human mutation.

Microsatellite instability in the insulin–like growth factor II receptor gene in gastrointestinal tumours

B. Leggett, S. Powell, Suna Wang, 1996, Nature Genetics.

Neoplastic progression occurs through mutator pathways in hyperplastic polyposis of the colorectum

J. Palazzo, B. Leggett, R. Fishel, 2000, Gut.

Fas ligand and tumour counter‐attack in colorectal cancer stratified according to microsatellite instability status

B. Leggett, M. Cummings, G. Radford-Smith, 2003, The Journal of pathology.

Genomic instability occurs in colorectal carcinomas but not in adenomas

G. Chenevix-Trench, B. Leggett, J. Searle, 1993, Human mutation.

Frequency of mutation and deletion of the tumor suppressor gene CDKN2A (MTS1/p16) in hepatocellular carcinoma from an Australian population

B. Leggett, J. Young, J. Searle, 1997, Hepatology.

A family with attenuated familial adenomatous polyposis due to a mutation in the alternatively spliced region of APC exon 9

B. Leggett, L. Simms, G. Anderson, 1998, Human mutation.

Analysis of genetic and phenotypic heterogeneity in juvenile polyposis

W. Bodmer, R. Houlston, B. Leggett, 2000, Gut.

An Alu VpA Marker on chromosome 1 demonstrates that replication errors manifest at the adenoma‐carcinoma transition in sporadic colorectal tumors

G. Chenevix-Trench, B. Leggett, J. Searle, 1995, Genes, chromosomes & cancer.

Corrigendum: The insulin–like growth factor II receptor gene is a target of microsatellite instability in human gastrointestinal tumours

B. Leggett, S. Powell, Suna Wang, 1996, Nature Genetics.

Severe upper gastrointestinal polyposis associated with sparse colonic polyposis in a familial adenomatous polyposis family with an APC mutation at codon 1520

B. Leggett, J. Young, R. Buttenshaw, 1997, Gut.

Features of colorectal cancers with high-level microsatellite instability occurring in familial and sporadic settings: parallel pathways of tumorigenesis.

B. Leggett, J. Jass, L. Simms, 2001, The American journal of pathology.

Morphology of sporadic colorectal cancer with DNA replication errors

K. Do, B. Leggett, J. Jass, 1998, Gut.

Mutations in DPC4 (SMAD4) cause juvenile polyposis syndrome, but only account for a minority of cases.

W. Bodmer, R. Houlston, B. Leggett, 1998, Human molecular genetics.

Distinction between familial and sporadic forms of colorectal cancer showing DNA microsatellite instability.

B. Leggett, L. Simms, J. Young, 2002, European journal of cancer.

Mucin core protein expression in colorectal cancers with high levels of microsatellite instability indicates a novel pathway of morphogenesis.

B. Leggett, J. Jass, L. Simms, 2000, Clinical cancer research : an official journal of the American Association for Cancer Research.

Angiogenic factor VEGF is decreased in human colorectal neoplasms showing DNA microsatellite instability

B. Leggett, L. Simms, J. Jass, 1999, The Journal of pathology.

Methylation patterns define two types of hyperplastic polyp associated with colorectal cancer

B. Leggett, J. Jass, J. Young, 2004, Gut.

Biological significance of microsatellite instability-low (MSI-L) status in colorectal tumors.

B. Leggett, J. Jass, R. Ward, 2001, The American journal of pathology.

APC mutation and tumour budding in colorectal cancer

B. Leggett, J. Jass, V. Whitehall, 2003, Journal of clinical pathology.

p73 Is up‐regulated in a subset of hepatocellular carcinomas

B. Leggett, K. Khanna, V. Whitehall, 2000, Hepatology.

Loss of heterozygosity on the long arm of chromosome 11 in colorectal tumours.

G. Chenevix-Trench, B. Leggett, J. Young, 1994, British Journal of Cancer.

Tumour infiltrating lymphocytes and apoptosis are independent features in colorectal cancer stratified according to microsatellite instability status

B. Leggett, J. Jass, L. Simms, 2001, Gut.

Detection of telomerase activity in biopsy samples of colorectal cancer

J. Jass, D. Fang, Yuan‐hui Luo, 1999, Journal of gastroenterology and hepatology.

Promoter methylation of the mutated in colorectal cancer gene is a frequent early event in colorectal cancer

P. Laird, B. Leggett, J. Jass, 2007, Oncogene.

Methylation patterns define two types of hyperplastic polyp associated with colorectal cancer

B. Leggett, T. Higuchi, J. Jass, 2004, Gut.

Low level microsatellite instability may be associated with reduced cancer specific survival in sporadic stage C colorectal carcinoma

B. Leggett, J. Jass, J. Young, 2004, Gut.

Infrequent loss of heterozygosity of APC/MCC and DCC genes in gastric cancer showing DNA microsatellite instability.

J. Young, J. Jass, D. Fang, 1999, Journal of clinical pathology.

Colorectal carcinomas show frequent allelic loss on the long arm of chromosome 17 with evidence for a specific target region.

G. Chenevix-Trench, B. Leggett, J. Young, 1995, British Journal of Cancer.

Loss of heterozygosity on the long arm of chromosome 11 in colorectal tumours.

G. Chenevix-Trench, B. Leggett, J. Searle, 1994, British Journal of Cancer.