Gilles Hanquet

发表

Development of novel oxotriazinoindole inhibitors of aldose reductase: isosteric sulfur/oxygen replacement in the thioxotriazinoindole cemtirestat markedly improved inhibition selectivity.

G. Hanquet, M. Prnova, Lucia Kovacikova, 2019, Journal of medicinal chemistry.

Novel substituted N-benzyl(oxotriazinoindole) inhibitors of aldose reductase exploiting ALR2 unoccupied interactive pocket.

G. Hanquet, Lucia Kovacikova, M. Šoltésová Prnová, 2020, Bioorganic & medicinal chemistry.

Asymmetric synthesis of syn and anti 1,2-diols from diethyl oxalate using the stereoselective sulfoxide directed reduction of 1,2-diketone derivatives

I. Izzo, G. Solladié, G. Hanquet, 1999 .

Solvent-and structure-dependent regioselectivity in the boron-mediated aldol reaction of 2 -(1,3 -Dioxolan -2 -yl )ethyl ethyl ketones

G. Hanquet, Naïma Khiri, H. Norouzi‐Arasi, 2007 .

Efficient asymmetric synthesis of aryl difluoromethyl sulfoxides and their use to access enantiopure α-difluoromethyl alcohols

M. Castello, G. Hanquet, A. Panossian, 2019, Tetrahedron.

Access towards enantiopure α,α-difluoromethyl alcohols by means of sulfoxides as traceless chiral auxiliaries.

G. Hanquet, A. Panossian, F. Leroux, 2018, Chemical communications.

New synthesized polyoxygenated diarylheptanoids suppress lipopolysaccharide-induced neuroinflammation.

P. Convertini, A. Santarsiero, V. Infantino, 2020, Biochemical and biophysical research communications.

Diastereoselective synthesis of the C14–C29 fragment of amphidinol.

J. Cossy, G. Hanquet, S. Reymond, 2013, Organic & biomolecular chemistry.

Iron-catalyzed cross-coupling between C-bromo mannopyranoside derivatives and a vinyl Grignard reagent: toward the synthesis of the C31–C52 fragment of amphidinol 3

J. Cossy, G. Hanquet, S. Reymond, 2013 .

Ring-Closing of 1,7- and 1,8-Enynes of Propargylic O,O-Acetals by Ruthenium-Catalysed Intramolecular Metathesis

Christophe Bour, G. Hanquet, D. Lanfranchi, 2010 .

Recent synthetic methods towards the –OCHF2 moiety

F. Toulgoat, G. Hanquet, A. Panossian, 2021, Tetrahedron.

Diastereoselective synthesis of the C17-C30 fragment of amphidinol 3.

D. Hazelard, J. Cossy, T. Kreuzer, 2012, Organic & biomolecular chemistry.

Enantioselective Access to Key Intermediates for Salvinorin A and Analogues

Christophe Bour, G. Hanquet, D. Lanfranchi, 2011 .

Preparation of enantiomerically pure (E)-β-sulfinylenones from β-ketoesters

G. Solladié, Naïma Khiri, A. Lefranc, 2005 .

Enantioselective sulfoxide-directed preparation of 1,2-diols from oxalic compounds: formal synthesis of the 10-membered lactone core of ascidiatrienolides and didemnilactones

I. Izzo, G. Solladié, G. Hanquet, 2005 .

Ring-opening of lactones with enolate nucleophiles: a simple access to functionalised β-ketoesters, β,δ-diketoesters and β-ketosulfoxides

G. Solladié, G. Hanquet, Naïma Khiri, 2005 .

New insights into the reduction of β,δ-diketo-sulfoxides

G. Solladié, G. Hanquet, Xavier J Salom-Roig, 2003 .

Recent developments in chiral non-racemic sulfinyl group chemistry in asymmetric synthesis

G. Solladié, G. Hanquet, F. Colobert, 2003 .

Aryl Fluoroalkyl Sulfoxides: Optical Stability and p K a Measurement

M. Elhabiri, N. Vanthuyne, G. Hanquet, 2021, European Journal of Organic Chemistry.

Comprehensive Study and Development of a Metal-Free and Mild Nucleophilic Trifluoromethoxylation.

F. Toulgoat, A. Panossian, T. Billard, 2023, Chemistry.

Synthesis, biological evaluation and molecular modeling studies on novel quinonoid inhibitors of CDC25 phosphatases

M. Mori, Christophe Bour, B. Botta, 2016, Journal of enzyme inhibition and medicinal chemistry.

Ynamide Click chemistry in development of triazole VEGFR2 TK modulators.

R. Cetin-Atalay, G. Hanquet, Juraj Dobiáš, 2015, European journal of medicinal chemistry.

Novel CLK1 inhibitors based on N-aryloxazol-2-amine skeleton - A possible way to dual VEGFR2 TK/CLK ligands.

Juraj Dobiáš, G. Addová, A. Boháč, 2017, European journal of medicinal chemistry.

Direct Deprotonative Functionalization of α,α-Difluoromethyl Ketones using a Catalytic Organosuperbase.

K. Mikami, A. Panossian, F. Leroux, 2023, Angewandte Chemie.

Study of Carbamoyl Fluoride: Synthesis, Properties and Applications.

F. Toulgoat, A. Panossian, F. Leroux, 2022, Chemistry.

Synthesis and use of trifluoromethylthiolated ketenimines.

T. Guérin, G. Hanquet, A. Panossian, 2020, Chemistry.

Study of a Stable "Trifluoromethoxide Anion Solution" Arising from 2,4-Dinitro-Trifluoromethoxybenzene.

F. Toulgoat, G. Hanquet, F. Leroux, 2021, Chemistry.

Direct Trifluoromethoxylation without OCF 3 ‐Carrier through In Situ Generation of Fluorophosgene

G. Hanquet, A. Panossian, F. Leroux, 2021 .

Quinoides and VEGFR2 TKIs influence the fate of hepatocellular carcinoma and its cancer stem cells.

R. Cetin-Atalay, D. Kahraman, A. Boháč, 2017, MedChemComm.

Asymmetric Diels-Alder reactions of a new enantiomerically pure sulfinylquinone: a straightforward access to functionalized Wieland-Miescher ketone analogues with (R) absolute configuration.

D. Lanfranchi, Gilles Hanquet, 2006, The Journal of organic chemistry.

Selected Methodologies Convenient for the Synthesis of N,5‐Diaryloxazole‐2‐amine Pharmacophore

G. Hanquet, Lucia Kovacikova, A. Boháč, 2015 .

Isolation, structural determination and synthetic approaches toward amphidinol 3.

J. Cossy, G. Hanquet, S. Reymond, 2014, Natural product reports.

Switchable Diastereoselectivity in the Fluoride-Promoted Vinylogous Mukaiyama-Michael Reaction of 2-[(Trimethylsilyl)oxy]furan Catalyzed by Crown Ethers.

Y. Minenkov, L. Cavallo, R. Schettini, 2017, The Journal of organic chemistry.

Isomerisation of (E)‐2‐Tetrahydrofurylidenealkanecarboxylic Esters and Amides into Their (Z) Isomers by Chelation Control with Metallated Bases or Lewis Acids

G. Solladié, G. Hanquet, Xavier J Salom-Roig, 2002 .