George Stark Stark

Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins.

J. Darnell, G. Stark, I. Kerr, 1994, Science.

Expression of the terminal protein region of hepatitis B virus inhibits cellular responses to interferons alpha and gamma and double-stranded RNA.

H. Thomas, G. Stark, I. Kerr, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Different relative activities of human cell-derived interferon-alpha subtypes: IFN-alpha 8 has very high antiviral potency.

H. Thomas, G. Stark, G. Foster, 1996, Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research.

DNA amplification is rare in normal human cells.

F. Watt, G. Stark, H. Smith, 1990, Proceedings of the National Academy of Sciences of the United States of America.

Complementation of a mutant cell line: central role of the 91 kDa polypeptide of ISGF3 in the interferon‐alpha and ‐gamma signal transduction pathways.

G. Stark, I. Kerr, C. Schindler, 1993, The EMBO journal.

Roles of JAKs in activation of STATs and stimulation of c-fos gene expression by epidermal growth factor

D. Levy, G. Stark, I. Kerr, 1996, Molecular and cellular biology.

Kinase‐negative mutants of JAK1 can sustain interferon‐gamma‐inducible gene expression but not an antiviral state.

G. Stark, I. Kerr, J. Ihle, 1996, The EMBO journal.

Single-copy and amplified CAD genes in Syrian hamster chromosomes localized by a highly sensitive method for in situ hybridization.

G. Wahl, G. Stark, R. Padgett, 1982, Molecular and cellular biology.

Transcription factor ISGF-3 formation requires phosphorylated Stat91 protein, but Stat113 protein is phosphorylated independently of Stat91 protein.

J. Darnell, G. Stark, I. Kerr, 1994, Proceedings of the National Academy of Sciences of the United States of America.

A p53-dependent S-phase checkpoint helps to protect cells from DNA damage in response to starvation for pyrimidine nucleotides.

G. Stark, W. Taylor, M. Agarwal, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Molecular analysis of G1B and G3A IFN gamma mutants reveals that defects in CIITA or RFX result in defective class II MHC and Ii gene induction.

G. Stark, J. M. Boss, K. Wright, 1994, Immunity.

The role of p53 in regulating genomic stability when DNA and RNA synthesis are inhibited.

G. Stark, M. V. Chernov, W. Taylor, 1995, Trends in biochemical sciences.