W. H. Haile

发表

Inhibition of human folylpolyglutamate synthetase by diastereomeric phosphinic acid mimics of the tetrahedral intermediate.

J. Coward, J. McGuire, W. Haile, 2009, Archives of biochemistry and biophysics.

Potent inhibition of human folylpolyglutamate synthetase by a phosphinic acid mimic of the tetrahedral reaction intermediate.

J. Coward, J. McGuire, W. Haile, 2003, Biochemical pharmacology.

Mechanism-based inhibition of human folylpolyglutamate synthetase: design, synthesis, and biochemical characterization of a phosphapeptide mimic of the tetrahedral intermediate.

T. Tsukamoto, J. Coward, J. McGuire, 1998, Archives of biochemistry and biophysics.

Metabolism-blocked antifolates as potential anti-rheumatoid arthritis agents: 4-amino-4-deoxy-5,8,10-trideazapteroyl-d,l-4'-methyleneglutamic acid (CH-1504) and its analogs.

J. McGuire, W. Haile, W. H. Haile, 2009, Biochemical pharmacology.

5-amino-4-imidazolecarboxamide riboside potentiates both transport of reduced folates and antifolates by the human reduced folate carrier and their subsequent metabolism.

J. McGuire, W. Haile, C. Yeh, 2006, Cancer research.

Cross-resistance studies of folylpolyglutamate synthetase-deficient, methotrexate-resistant CCRF-CEM human leukemia sublines.

J. McGuire, C. Russell, D. McCloskey, 1993, Leukemia.

Biological properties of fluoroglutamate-containing analogs of folates and methotrexate with altered capacities to form poly (gamma-glutamate) metabolites.

M. Rhee, J. Coward, J. Galivan, 1996, Biochemical pharmacology.

Synthesis and biological activity of folic acid and methotrexate analogues containing L-threo-(2S,4S)-4-fluoroglutamic acid and DL-3,3-difluoroglutamic acid.

J. Coward, J. McGuire, W. Bolanowska, 1996, Journal of medicinal chemistry.

Potent inhibition of human folylpolyglutamate synthetase by suramin.

J. McGuire, W. H. Haile, 1996, Archives of biochemistry and biophysics.

Synthesis and Biological Evaluation of Nα-(4-Amino-4-deoxy-10- methylpteroyl)-DL-4,4-difluoroornithine.

T. Tsukamoto, J. Coward, J. McGuire, 1996 .

Studies on the cross resistance of folylpolyglutamate synthetase-deficient, methotrexate-resistant CCRF-CEM human leukemia sublines.

J. McGuire, C. Russell, D. McCloskey, 1993, Advances in experimental medicine and biology.

Evolution of drug resistance in CCRF-CEM human leukemia cells selected by intermittent methotrexate exposure.

B. Shane, J. McGuire, C. Russell, 1995, Oncology research.