J. Kelly

发表

Simple and Inexpensive Fluorescence-Based Technique for High-Throughput Antimalarial Drug Screening

P. Wilairat, N. Sriwilaijaroen, M. Riscoe, 2004, Antimicrobial Agents and Chemotherapy.

A chloroquine-like molecule designed to reverse resistance in Plasmodium falciparum.

S. Burgess, M. Riscoe, D. Peyton, 2006, Journal of medicinal chemistry.

Design, Synthesis, and Evaluation of 10-N-Substituted Acridones as Novel Chemosensitizers in Plasmodium falciparum

A. Janowsky, Robert A. Johnson, D. Hinrichs, 2007, Antimicrobial Agents and Chemotherapy.

Quinolone-3-Diarylethers: A New Class of Antimalarial Drug

Yuexin Li, David M. Shackleford, Susan A Charman, 2013, Science Translational Medicine.

Simplified Reversed Chloroquines To Overcome Malaria Resistance to Quinoline-Based Drugs

S. Burgess, D. Peyton, M. Smilkstein, 2017, Antimicrobial Agents and Chemotherapy.

Sontochin as a Guide to the Development of Drugs against Chloroquine-Resistant Malaria

D. Hinrichs, K. Wegmann, M. Riscoe, 2012, Antimicrobial Agents and Chemotherapy.

Optimization of Xanthones for Antimalarial Activity: the 3,6-Bis-ω-Diethylaminoalkoxyxanthone Series

D. Hinrichs, M. Riscoe, D. Peyton, 2002, Antimicrobial Agents and Chemotherapy.

Unsymmetrical Bisquinolines with High Potency against P. falciparum Malaria

S. Burgess, D. Peyton, Yuexin Li, 2020, Molecules.

ELQ-331 as a prototype for extremely durable chemoprotection against malaria

S. Kappe, D. Koop, L. Bleyle, 2019, Malaria Journal.

Xanthones as antimalarial agents: discovery, mode of action, and optimization.

M. Riscoe, R. Winter, J. X. Kelly, 2005, Current medicinal chemistry.

ELQ-300 Prodrugs for Enhanced Delivery and Single-Dose Cure of Malaria

David M. Shackleford, Galen P. Miley, M. Mather, 2015, Antimicrobial Agents and Chemotherapy.

Discovery, Synthesis, and Optimization of Antimalarial 4(1H)-Quinolone-3-Diarylethers

Galen P. Miley, M. Mather, A. Vaidya, 2014, Journal of medicinal chemistry.

Optimization of endochin-like quinolones for antimalarial activity.

D. Koop, D. Hinrichs, M. Riscoe, 2011, Experimental parasitology.

Evaluation and lead optimization of anti-malarial acridones.

D. Hinrichs, M. Riscoe, M. Smilkstein, 2006, Experimental parasitology.

Synthesis, structure-activity relationship, and mode-of-action studies of antimalarial reversed chloroquine compounds.

R. Brun, S. Burgess, S. Wittlin, 2010, Journal of medicinal chemistry.

Atovaquone and ELQ-300 Combination Therapy as a Novel Dual-Site Cytochrome bc1 Inhibition Strategy for Malaria

A. Vaidya, J. Morrisey, Isaac P. Forquer, 2016, Antimicrobial Agents and Chemotherapy.

Inhibition of cytochrome bc1 as a strategy for single-dose, multi-stage antimalarial therapy.

Galen P. Miley, M. Mather, A. Vaidya, 2015, The American journal of tropical medicine and hygiene.

Discovery and Structural Optimization of Acridones as Broad-Spectrum Antimalarials.

John C. Tan, D. Caridha, Q. Zeng, 2019, Journal of medicinal chemistry.

Antimalarial quinolones: synthesis, potency, and mechanistic studies.

David Hinrichs, D. Hinrichs, M. Riscoe, 2008, Experimental parasitology.

Alkoxycarbonate Ester Prodrugs of Preclinical Drug Candidate ELQ-300 for Prophylaxis and Treatment of Malaria.

R. F. Campbell, M. Mather, A. Vaidya, 2017, ACS infectious diseases.

Selective killing of the human malaria parasite Plasmodium falciparum by a benzylthiazolium dye.

D. Hinrichs, M. Riscoe, Theodore P. Braun, 2007, Experimental parasitology.

Synthesis and Structure−Activity Relationships of Synthesis and Structure−Activity Relationships of Tambjamines and B ‑ Ring Functionalized Tambjamines and B Ring Functionalized Prodiginines as Potent Antimalarials Prodiginines as Potent Antimalarials

K. Reynolds, J. X. Kelly, P. Kancharla, 2018 .

Total Synthesis and Antimalarial Activity of 2-(p-Hydroxybenzyl)-prodigiosins, Isoheptylprodigiosin, and Geometric Isomers of Tambjamine MYP1 Isolated from Marine Bacteria.

K. Reynolds, Yuexin Li, J. X. Kelly, 2021, Journal of medicinal chemistry.

The kinetics of uptake and accumulation of 3,6-bis-omega-diethylamino-amyloxyxanthone by the human malaria parasite Plasmodium falciparum.

A. Cornea, D. Hinrichs, M. Riscoe, 2002, Molecular and biochemical parasitology.

Antimalarial activity of natural and synthetic prodiginines.

Shweta, G. Challis, K. Reynolds, 2011, Journal of medicinal chemistry.

Diphenylether-Modified 1,2-Diamines with Improved Drug Properties for Development against Mycobacterium tuberculosis.

D. Koop, P. Davidson, M. Riscoe, 2016, ACS infectious diseases.

Lead Optimization of Second-Generation Acridones as Broad-Spectrum Antimalarials.

P. Rosenthal, K. Reynolds, D. Caridha, 2020, Journal of medicinal chemistry.

Quinolone-3-Diarylethers : A new class of drugs for a new era of malaria eradication

David M. Shackleford, R. Price, M. Mather, 2014 .

Reversal agent and linker variants of reversed chloroquines: activities against Plasmodium falciparum.

Simeon S. Andrews, S. Burgess, D. Peyton, 2010, Journal of medicinal chemistry.

A spectroscopic investigation of the binding interactions between 4,5-dihydroxyxanthone and heme.

M. Riscoe, D. Peyton, R. Winter, 2001, Journal of inorganic biochemistry.

Antileishmanial drug development: exploitation of parasite heme dependency.

H. Bouwer, M. Ignatushchenko, D. Hinrichs, 2003, Molecular and biochemical parasitology.

Cyquant cell proliferation assay as a fluorescence-based method for in vitro screening of antimalarial activity.

P. Wilairat, N. Sriwilaijaroen, M. Riscoe, 2004, The Southeast Asian journal of tropical medicine and public health.

Discovery of dual function acridones as a new antimalarial chemotype

A. Janowsky, Robert A. Johnson, R. Brun, 2009, Nature.

A drug-selected Plasmodium falciparum lacking the need for conventional electron transport.

D. Kramer, A. Kanazawa, D. Hinrichs, 2008, Molecular and biochemical parasitology.