B. Crawford

发表

Hereditary multiple exostoses and heparan sulfate polymerization.

J. Esko, B. E. Crawford, Beverly M Zak, 2002, Biochimica et biophysica acta.

Biosynthesis of the Linkage Region of Glycosaminoglycans

T. Hennet, J. Esko, Dapeng Zhou, 2001, The Journal of Biological Chemistry.

Central nervous system pathology in preclinical MPS IIIB dogs reveals progressive changes in clinically relevant brain regions

J. Cooper, Emma McCullagh, N. M. Ellinwood, 2020, Scientific Reports.

Cell Surface Heparan Sulfate Promotes Replication of Toxoplasma gondii

J. Esko, J. R. Bishop, B. E. Crawford, 2005, Infection and Immunity.

Enzyme augmentation therapy enhances the therapeutic efficacy of bone marrow transplantation in mucopolysaccharidosis type II mice.

H. Nakauchi, Y. Eto, J. Brown, 2014, Molecular genetics and metabolism.

Tralesinidase Alfa Enzyme Replacement Therapy Prevents Disease Manifestations in a Canine Model of Mucopolysaccharidosis Type IIIB

B. Mueller, Jodi D. Smith, J. Cooper, 2022, The Journal of Pharmacology and Experimental Therapeutics.

Biochemical evaluation of intracerebroventricular rhNAGLU-IGF2 enzyme replacement therapy in neonatal mice with Sanfilippo B syndrome.

J. Cooper, M. Sands, P. Dickson, 2021, Molecular genetics and metabolism.

Differential Uptake of NAGLU-IGF2 and Unmodified NAGLU in Cellular Models of Sanfilippo Syndrome Type B

J. LeBowitz, R. Lawrence, Bryan K. Yip, 2019, Molecular therapy. Methods & clinical development.

Clearance of Heparan Sulfate and Attenuation of CNS Pathology by Intracerebroventricular BMN 250 in Sanfilippo Type B Mice

P. Fitzpatrick, S. Bunting, Catherine Vitelli, 2017, Molecular therapy. Methods & clinical development.

Delivery of an enzyme-IGFII fusion protein to the mouse brain is therapeutic for mucopolysaccharidosis type IIIB

P. Fitzpatrick, S. Bunting, A. Bagri, 2014, Proceedings of the National Academy of Sciences.

Genistein Improves Neuropathology and Corrects Behaviour in a Mouse Model of Neurodegenerative Metabolic Disease

G. Węgrzyn, J. Brown, B. Bigger, 2010, PloS one.

Glycan-based biomarkers for mucopolysaccharidoses.

J. Esko, P. Dickson, J. Brown, 2014, Molecular genetics and metabolism.

Disease-Specific Non-Reducing End Carbohydrate Biomarkers for Mucopolysaccharidoses

J. Esko, G. Boons, J. Brown, 2011, Nature chemical biology.

Glycan Antagonists and Inhibitors: A Fount for Drug Discovery

J. Esko, J. Brown, B. E. Crawford, 2007, Critical reviews in biochemistry and molecular biology.

Translational studies of intravenous and intracerebroventricular routes of administration for CNS cellular biodistribution for BMN 250, an enzyme replacement therapy for the treatment of Sanfilippo type B

A. Shaywitz, P. Fitzpatrick, S. Bunting, 2020, Drug Delivery and Translational Research.

Intracerebroventricular dosing of N-sulfoglucosamine sulfohydrolase in mucopolysaccharidosis IIIA mice reduces markers of brain lysosomal dysfunction

S. Bunting, S. Fong, Britta Handyside, 2022, The Journal of biological chemistry.

Evaluation of non-reducing end pathologic glycosaminoglycan detection method for monitoring therapeutic response to enzyme replacement therapy in human mucopolysaccharidosis I.

Agnes H. Chen, P. Dickson, M. Vera, 2020, Molecular genetics and metabolism.

A. Shaywitz, P. Fitzpatrick, S. Bunting, 2020, Drug Delivery and Translational Research.

Intracerebroventricular enzyme replacement therapy with β-galactosidase reverses brain pathologies due to GM1 gangliosidosis in mice

S. Bunting, S. Fong, Britta Handyside, 2019, The Journal of Biological Chemistry.

BMN 250, a fusion of lysosomal alpha-N-acetylglucosaminidase with IGF2, exhibits different patterns of cellular uptake into critical cell types of Sanfilippo syndrome B disease pathogenesis

J. LeBowitz, R. Lawrence, Bryan K. Yip, 2018, bioRxiv.

Disease correction by combined neonatal intracranial AAV and systemic lentiviral gene therapy in Sanfilippo Syndrome type B mice

John L. Orrock, E. Herzog, C. Heldermon, 2013, Gene Therapy.

Genetic ablation of acid ceramidase in Krabbe disease confirms the psychosine hypothesis and identifies a new therapeutic target

J. Medin, D. Wozniak, Yedda Li, 2019, Proceedings of the National Academy of Sciences.

Substrate reduction therapy for Krabbe disease and metachromatic leukodystrophy using a novel ceramide galactosyltransferase inhibitor

M. Sands, Ying Feng, Q. Chao, 2021, Scientific reports.

Etiological point mutations in the hereditary multiple exostoses gene EXT1: a functional analysis of heparan sulfate polymerase activity.

J. Esko, C. McCormick, P. Cheung, 2001, American journal of human genetics.

Lettuce infectious yellows virus: in vitro acquisition analysis using partially purified virions and the whitefly Bemisia tabaci.

B. Falk, H. Yeh, L. Rubio, 1999, The Journal of general virology.

Surfen, a small molecule antagonist of heparan sulfate

C. Glass, J. Esko, Lianchun Wang, 2008, Proceedings of the National Academy of Sciences.

Characterization of disease-specific chondroitin sulfate non-reducing end accumulation in mucopolysaccharidosis IVA.

B. Burton, M. Pasquali, R. Lawrence, 2020, Glycobiology.

Guanidinylated Neomycin Delivers Large, Bioactive Cargo into Cells through a Heparan Sulfate-dependent Pathway*

J. Esko, Y. Tor, O. Garner, 2007, Journal of Biological Chemistry.

Natural history study of glycan accumulation in large animal models of GM2 gangliosidoses

Emma McCullagh, R. Lawrence, Linley Mangini, 2020, PloS one.

Characterization of glycan substrates accumulating in GM1 Gangliosidosis

W. Clark, R. Giugliani, J. LeBowitz, 2019, Molecular genetics and metabolism reports.

Essential Alterations of Heparan Sulfate During the Differentiation of Embryonic Stem Cells to Sox1‐Enhanced Green Fluorescent Protein‐Expressing Neural Progenitor Cells

Austin G Smith, J. Esko, T. V. van Kuppevelt, 2007, Stem cells.

Loss of the Heparan Sulfate Sulfotransferase, Ndst1, in Mammary Epithelial Cells Selectively Blocks Lobuloalveolar Development in Mice

J. Esko, S. Nigam, O. Garner, 2010, PloS one.

Becker Digital

Emma McCullagh, J. Pinkstaff, J. Jens, 2023 .

Specific antibody titer alters the effectiveness of intrathecal enzyme replacement therapy in canine mucopolysaccharidosis I.

P. Dickson, M. Vera, J. Brown, 2012, Molecular genetics and metabolism.

Toxoplasma gondii Replication of Cell Surface Heparan Sulfate Promotes

J. Esko, J. R. Bishop, B. Crawford, 2005 .

N-Sulfation of Heparan Sulfate Regulates Early Branching Events in the Developing Mammary Gland*

J. Esko, S. Nigam, O. Garner, 2012, The Journal of Biological Chemistry.