Upinder Singh

发表

Regulation of H2O2 Stress-responsive Genes through a Novel Transcription Factor in the Protozoan Pathogen Entamoeba histolytica*

U. Singh, L. Morf, R. Pearson, 2012, The Journal of Biological Chemistry.

Novel Live Alkaline Phosphatase Substrate for Identification of Pluripotent Stem Cells

M. Rao, K. Gee, Scott Grecian, 2012, Stem Cell Reviews and Reports.

Cults and shrines in early historical Mathura (c. 200 bc-ad 200)

U. Singh, Upinder Singh, 2004 .

Identification of plicamycin, TG02, panobinostat, lestaurtinib, and GDC-0084 as promising compounds for the treatment of central nervous system infections caused by the free-living amebae Naegleria, Acanthamoeba and Balamuthia

U. Singh, A. Debnath, Emily Chen, 2019, International journal for parasitology. Drugs and drug resistance.

Nucleus-localized Antisense Small RNAs with 5′-Polyphosphate Termini Regulate Long Term Transcriptional Gene Silencing in Entamoeba histolytica G3 Strain*

U. Singh, Hanbang Zhang, Vy Tran, 2011, The Journal of Biological Chemistry.

RNA interference in Entamoeba histolytica: implications for parasite biology and gene silencing.

U. Singh, Hanbang Zhang, Justine M. Pompey, 2011, Future microbiology.

Recent advances in Entamoeba biology: RNA interference, drug discovery, and gut microbiome

P. Morgado, U. Singh, D. Manna, 2016, F1000Research.

Recent advances in biology : RNA interference , drug Entamoeba discovery , and gut microbiome

P. Morgado, U. Singh, D. Manna, 2016 .

A Single RNaseIII Domain Protein from Entamoeba histolytica Has dsRNA Cleavage Activity and Can Help Mediate RNAi Gene Silencing in a Heterologous System

Xiaoping Zhou, U. Singh, Justine M. Pompey, 2015, PloS one.

RNAi Pathway Genes Are Resistant to Small RNA Mediated Gene Silencing in the Protozoan Parasite Entamoeba histolytica

U. Singh, Justine M. Pompey, L. Morf, 2014, PloS one.

Small RNAs with 5′-Polyphosphate Termini Associate with a Piwi-Related Protein and Regulate Gene Expression in the Single-Celled Eukaryote Entamoeba histolytica

J. Hackney, U. Singh, Hanbang Zhang, 2008, PLoS pathogens.

A History of Ancient and Early Medieval India: From the Stone Age to the 12th Century

U. Singh, Upinder Singh, Upinder Singh, 2009 .

Identification of oligo-adenylated small RNAs in the parasite Entamoeba and a potential role for small RNA control

N. Hall, U. Singh, Hanbang Zhang, 2020, BMC genomics.

Non-Templated Oligo-Adenylation of Small RNAs in the Parasite Entamoeba: Potential Roles for Small RNA Control in Single Celled Eukaryotic Pathogen

N. Hall, U. Singh, Hanbang Zhang, 2020 .

Structure and content of the Entamoeba histolytica genome.

T. Sicheritz-Pontén, N. Hall, C. Weber, 2007, Advances in parasitology.

Functional Characterization of Entamoeba histolytica Argonaute Proteins Reveals a Repetitive DR-Rich Motif Region That Controls Nuclear Localization

U. Singh, Hanbang Zhang, Vy Tran, 2019, mSphere.

Small RNAs and Regulation of Gene Expression in Entamoeba histolytica

U. Singh, L. Morf, Upinder Singh, 2015 .

Identification of pregnane X receptor ligands using time-resolved fluorescence resonance energy transfer and quantitative high-throughput screening.

Christopher P Austin, Anton Simeonov, James Inglese, 2009, Assay and drug development technologies.

Identification and characterization of differentiation mutants in the protozoan parasite Toxoplasma gondii

D. Roos, U. Singh, R. Donald, 2002, Molecular microbiology.

Genetic analysis of tachyzoite to bradyzoite differentiation mutants in Toxoplasma gondii reveals a hierarchy of gene induction

J. Boothroyd, U. Singh, Jeremy L. Brewer, 2002, Molecular microbiology.

Diagnosis and management of amebiasis.

U. Singh, W. Petri, Upinder Singh, 1999, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

263 – Entamoeba histolytica (Amebiasis)

U. Singh, C. Mcneil, Upinder Singh, 2012 .

Distinct Distal Gut Microbiome Diversity and Composition in Healthy Children from Bangladesh and the United States

Elisabeth M. Bik, Les Dethlefsen, David A. Relman, 2013, PloS one.

Identification of anisomycin, prodigiosin and obatoclax as compounds with broad-spectrum anti-parasitic activity

J. Derisi, C. Caffrey, U. Singh, 2020, PLoS neglected tropical diseases.

The genome of the protist parasite Entamoeba histolytica

Bernard B. Suh, B. Barrell, M. Pop, 2005, Nature.

Robust gene silencing mediated by antisense small RNAs in the pathogenic protist Entamoeba histolytica

U. Singh, A. Wang, L. Morf, 2013, Nucleic acids research.

Entamoeba histolytica modulates a complex repertoire of novel genes in response to oxidative and nitrosative stresses: implications for amebic pathogenesis

J. B. Vicente, M. Teixeira, U. Singh, 2009, Cellular microbiology.

Identification of developmentally regulated genes in Entamoeba histolytica: insights into mechanisms of stage conversion in a protozoan parasite

Rashidul Haque, R. Haque, J. Hackney, 2007, Cellular microbiology.

Impact of intestinal colonization and invasion on the Entamoeba histolytica transcriptome.

Zhangjun Fei, Mami Okada, Z. Fei, 2006, Molecular and biochemical parasitology.

Identification of Differentially Expressed Genes in Virulent and Nonvirulent Entamoeba Species: Potential Implications for Amebic Pathogenesis

U. Singh, R. MacFarlane, Ryan C. MacFarlane, 2006, Infection and Immunity.

Comparative Genomic Hybridizations of Entamoeba Strains Reveal Unique Genetic Fingerprints That Correlate with Virulence

J. Matese, J. Demeter, U. Singh, 2005, Eukaryotic Cell.

Genomic DNA microarrays for Entamoeba histolytica: applications for use in expression profiling and strain genotyping.

U. Singh, D. Bhattacharya, Ryan C. MacFarlane, 2005, Experimental parasitology.

CHAPTER 92 – Enteric Amebiasis

W. Petri, U. Singh, Kristine M. Peterson, 2011 .

Investigating amoebic pathogenesis usingEntamoeba histolytica DNA microarrays

U. Singh, P. Shah, Upinder Singh, 2002, Journal of Biosciences.

Disruption of a Locus Encoding a Nucleolar Zinc Finger Protein Decreases Tachyzoite-to-Bradyzoite Differentiation in Toxoplasma gondii

J. Boothroyd, U. Singh, O. Harb, 2005, Infection and Immunity.

RISC in Entamoeba histolytica: Identification of a Protein-Protein Interaction Network for the RNA Interference Pathway in a Deep-Branching Eukaryote

U. Singh, Hanbang Zhang, Sarah Bauer, 2021, mBio.

Small RNA pyrosequencing in the protozoan parasite Entamoeba histolytica reveals strain-specific small RNAs that target virulence genes

N. Hall, U. Singh, Hanbang Zhang, 2013, BMC Genomics.

Characterization of Extracellular Vesicles from Entamoeba histolytica Identifies Roles in Intercellular Communication That Regulates Parasite Growth and Development

P. Morgado, U. Singh, Hanbang Zhang, 2020, Infection and Immunity.

Toxoplasma gondii Asexual Development: Identification of Developmentally Regulated Genes and Distinct Patterns of Gene Expression

J. Boothroyd, U. Singh, Michael D. Cleary, 2002, Eukaryotic Cell.

High-Throughput Screening of Entamoeba Identifies Compounds Which Target Both Life Cycle Stages and Which Are Effective Against Metronidazole Resistant Parasites

U. Singh, D. Solow-Cordero, G. Ehrenkaufer, 2018, Front. Cell. Infect. Microbiol..

Antiparasitic therapy.

U. Singh, B. Blackburn, S. Kappagoda, 2011, Mayo Clinic proceedings.

Fast, cell-compatible click chemistry with copper-chelating azides for biomolecular labeling.

Scott T. Clarke, A. Ting, K. Gee, 2012, Angewandte Chemie.

Growth of the protozoan parasite Entamoeba histolytica in 5-azacytidine has limited effects on parasite gene expression

J. Hackney, U. Singh, I. Ali, 2007, BMC Genomics.

New insights into Entamoeba histolytica pathogenesis

U. Singh, Leigh A. Baxt, Upinder Singh, 2008, Current opinion in infectious diseases.

Development of RNA Interference Trigger-Mediated Gene Silencing in Entamoeba invadens

U. Singh, Hanbang Zhang, G. Ehrenkaufer, 2016, Infection and Immunity.

High Throughput Sequencing of Entamoeba 27nt Small RNA Population Reveals Role in Permanent Gene Silencing But No Effect on Regulating Gene Expression Changes during Stage Conversion, Oxidative, or Heat Shock Stress

N. Hall, U. Singh, Hanbang Zhang, 2015, PloS one.

An NAD+-dependent novel transcription factor controls stage conversion in Entamoeba

U. Singh, A. Bhat, C. Lentz, 2018, eLife.

The genome and transcriptome of the enteric parasite Entamoeba invadens, a model for encystation

N. Hall, H. Lorenzi, E. Caler, 2013, Genome Biology.

Functional Characterization of Spliceosomal Introns and Identification of U2, U4, and U5 snRNAs in the Deep-Branching Eukaryote Entamoeba histolytica

C. Davis, U. Singh, Michael P. S. Brown, 2007, Eukaryotic Cell.

An Entamoeba histolytica rhomboid protease with atypical specificity cleaves a surface lectin involved in phagocytosis and immune evasion.

S. Urban, R. Baker, Leigh A. Baxt, 2008, Genes & development.

Development and Applications of a Broad-Coverage, TR-FRET-Based Kinase Binding Assay Platform

U. Singh, Hildegard C. Eliason, K. Vogel, 2009, Journal of biomolecular screening.

Recent advances in Entamoeba biology: RNA interference, drug discovery, and gut microbiome

P. Morgado, Upinder Singh, Dipak Manna, 2016, F1000Research.

Transcriptional profiling of Entamoeba histolytica trophozoites.

U. Singh, P. Shah, Ryan C. MacFarlane, 2005, International journal for parasitology.

Identification of an Entamoeba histolytica Serine-, Threonine-, and Isoleucine-Rich Protein with Roles in Adhesion and Cytotoxicity

U. Singh, Ryan C. MacFarlane, Upinder Singh, 2007, Eukaryotic Cell.

Free-Living Amebas

U. Singh, B. Blackburn, A. Koshy, 2010 .

Context-dependent roles of the Entamoeba histolytica core promoter element GAAC in transcriptional activation and protein complex assembly.

U. Singh, C. Gilchrist, B. Mann, 2002, Molecular and biochemical parasitology.

Policy Recommendations for Optimizing the Infectious Diseases Physician-Scientist Workforce.

U. Singh, E. Lautenbach, C. Creech, 2018, The Journal of infectious diseases.

SYMPOSIUM ON ANTIMICROBIAL THERAPYAntiparasitic Therapy

B. Blackburn, S. Kappagoda, Upinder Singh, 2011 .

Dimethylated H3K27 Is a Repressive Epigenetic Histone Mark in the Protist Entamoeba histolytica and Is Significantly Enriched in Genes Silenced via the RNAi Pathway*

U. Singh, Bardees M. Foda, Upinder Singh, 2015, The Journal of Biological Chemistry.

Stress Response in Entamoeba histolytica Is Associated with Robust Processing of tRNA to tRNA Halves

U. Singh, Hanbang Zhang, G. Ehrenkaufer, 2021, bioRxiv.

Entamoeba histolytica rhomboid protease 1 has a role in migration and motility as validated by two independent genetic approaches.

U. Singh, L. Morf, Elena Rastew, 2015, Experimental parasitology.

Downregulation of an Entamoeba histolytica Rhomboid Protease Reveals Roles in Regulating Parasite Adhesion and Phagocytosis

U. Singh, D. Mirelman, R. Bracha, 2010, Eukaryotic Cell.

DNA microarrays in parasitology: strengths and limitations.

J. Boothroyd, U. Singh, Michael D. Cleary, 2003, Trends in parasitology.

Approaches to characterizing Entamoeba histolytica transcriptional regulation

U. Singh, R. Pearson, Upinder Singh, 2010, Cellular microbiology.

Oxidative stress resistance genes contribute to the pathogenic potential of the anaerobic protozoan parasite, Entamoeba histolytica.

J. B. Vicente, Elena Rastew, Upinder Singh, 2012, International journal for parasitology.

The discovery of ancient India : early archaeologists and the beginnings of archaeology

U. Singh, Upinder Singh, 2004 .

Entamoeba stage conversion: progress and new insights.

U. Singh, D. Manna, G. Ehrenkaufer, 2020, Current opinion in microbiology.

The NAD+ Responsive Transcription Factor ERM-BP Functions Downstream of Cellular Aggregation and Is an Early Regulator of Development and Heat Shock Response in Entamoeba

U. Singh, D. Manna, G. Ehrenkaufer, 2020, Frontiers in Cellular and Infection Microbiology.

Governing the State and the Self: Political Philosophy and Practice in the Edicts of Aśoka

U. Singh, Upinder Singh, 2012 .

Kingship, Violence and Non-violence in Indian Thought, c. 500 bce to 500 ce

Upinder Singh, 2020 .

A Detoxifying Oxygen Reductase in the Anaerobic Protozoan Entamoeba histolytica

J. B. Vicente, M. Teixeira, U. Singh, 2012, Eukaryotic Cell.