Karen Sommer

发表

Phosphorylation of the CARMA1 Linker Controls NF-κB Activation

David J. Rawlings, A. Bandaranayake, D. Rawlings, 2005 .

Safe and Effective Gene Therapy for Murine Wiskott-Aldrich Syndrome Using an Insulated Lentiviral Vector

D. Liggitt, A. Nienhuis, D. Rawlings, 2016, Molecular therapy. Methods & clinical development.

The CARMA1 signalosome links the signalling machinery of adaptive and innate immunity in lymphocytes

D. Rawlings, Miguel E. Moreno-García, K. Sommer, 2006, Nature Reviews Immunology.

Homology-Directed Recombination for Enhanced Engineering of Chimeric Antigen Receptor T Cells

A. Scharenberg, D. Rawlings, S. Jackson, 2017, Molecular therapy. Methods & clinical development.

Targeted gene editing restores regulated CD40L function in X-linked hyper-IgM syndrome.

H. Ochs, T. Torgerson, A. Scharenberg, 2016, Blood.

Efficient modification of CCR5 in primary human hematopoietic cells using a megaTAL nuclease and AAV donor template

A. Scharenberg, D. Rawlings, Jordan Jarjour, 2015, Science Translational Medicine.

Gene editing to induce FOXP3 expression in human CD4+ T cells leads to a stable regulatory phenotype and function

T. Torgerson, A. Scharenberg, D. Rawlings, 2020, Science Translational Medicine.

Effective, safe, and sustained correction of murine XLA using a UCOE-BTK promoter-based lentiviral vector

B. Ryu, D. Rawlings, Joseph Pangallo, 2021, Molecular therapy. Methods & clinical development.

Engineering HIV-Resistant, Anti-HIV Chimeric Antigen Receptor T Cells.

A. Scharenberg, D. Rawlings, Thor A Wagner, 2017, Molecular therapy : the journal of the American Society of Gene Therapy.

Elevated retinoic acid receptor beta(4) protein in human breast tumor cells with nuclear and cytoplasmic localization.

P. Treuting, Lynne T. Smith, K. Swisshelm, 1999, Proceedings of the National Academy of Sciences of the United States of America.

Kinase-Independent Feedback of the TAK1/TAB1 Complex on BCL10 Turnover and NF-κB Activation

J. Ninomiya-Tsuji, Michelle Brault, D. Rawlings, 2013, Molecular and Cellular Biology.

Pancreatic islet-specific engineered Tregs exhibit robust antigen-specific and bystander immune suppression in type 1 diabetes models

P. Linsley, D. Liggitt, D. Rawlings, 2022, Science Translational Medicine.

Efficient Modification of the CCR5 Locus in Primary Human T Cells With megaTAL Nuclease Establishes HIV-1 Resistance

B. Stoddard, D. Rawlings, H. Kiem, 2016, Molecular therapy. Nucleic acids.

Tec Kinases Mediate Sustained Calcium Influx via Site-specific Tyrosine Phosphorylation of the Phospholipase Cγ Src Homology 2-Src Homology 3 Linker*

D. Rawlings, R. Kato, J. Daniel, 2004, Journal of Biological Chemistry.

Phosphorylation of the CARMA1 linker controls NF-kappaB activation.

A. Bandaranayake, D. Rawlings, J. Pomerantz, 2005, Immunity.

PKC-β controls IκB kinase lipid raft recruitment and activation in response to BCR signaling

M. Teitell, R. Wall, D. Rawlings, 2002, Nature Immunology.

PKC-beta controls I kappa B kinase lipid raft recruitment and activation in response to BCR signaling.

M. Teitell, R. Wall, D. Rawlings, 2002, Nature immunology.

Retinoids, Retinoic Acid Receptors, and Breast Cancer

W. Blaner, R. Moe, J. Paik, 2003, Cancer investigation.

Downstream Codons in the Retinoic Acid Receptor β-2 and β-4 mRNAs Initiate Translation of a Protein Isoform That Disrupts Retinoid-activated Transcription*

K. Swisshelm, K. Sommer, Lucinda I. Chen, 2002, The Journal of Biological Chemistry.

Bruton’s Tyrosine Kinase Revealed as a Negative Regulator of Wnt–β-Catenin Signaling

S. Haggarty, M. MacCoss, R. Moon, 2009, Science Signaling.

Wnt-{beta}-Catenin Signaling Bruton's Tyrosine Kinase Revealed as a Negative Regulator of `

M. MacCoss, M. Cleary, T. Biechele, 2012 .

Activated CARD11 accelerates germinal center kinetics, promoting mTORC1 and terminal differentiation

R. Chawla, D. Rawlings, R. James, 2018, The Journal of experimental medicine.

MAGUK-Controlled Ubiquitination of CARMA1 Modulates Lymphocyte NF-κB Activity

David J. Rawlings, A. Bandaranayake, D. Rawlings, 2009, Molecular and Cellular Biology.

Retinoic Acid Receptor β2 Inhibition of Metastasis in Mouse Mammary Gland Xenografts

M. Emond, V. Seewaldt, P. Treuting, 2002, Breast Cancer Research and Treatment.

Targeted gene editing restores regulated CD40L function in X-linked hyper-IgM syndrome.

H. Ochs, T. Torgerson, A. Scharenberg, 2016, Blood.

Proximal signals controlling B-cell antigen receptor (BCR) mediated NF-kappaB activation.

A. Bandaranayake, D. Rawlings, Miguel E. Moreno-García, 2006, Advances in experimental medicine and biology.

A Chemically Inducible IL-2 Receptor Signaling Complex Allows for Effective In Vitro and In Vivo selection of Engineered CD4+ T cells.

A. Scharenberg, D. Rawlings, Annaiz M. Grimm, 2023, Molecular therapy : the journal of the American Society of Gene Therapy.

Serine 649 Phosphorylation within the Protein Kinase C-Regulated Domain Down-Regulates CARMA1 Activity in Lymphocytes1

David J. Rawlings, D. Rawlings, C. Haftmann, 2009, The Journal of Immunology.

Efficient and sustained FOXP3 locus editing in hematopoietic stem cells as a therapeutic approach for IPEX syndrome

Iram Khan, Yuchi Honaker, Swati Singh, 2023, Molecular therapy. Methods & clinical development.