Z. Vlahcevic

发表

Conjugates of ursodeoxycholate protect against cholestasis and hepatocellular necrosis caused by more hydrophobic bile salts. In vivo studies in the rat.

P. Hylemon, W. Pandak, D. Heuman, 1991, Gastroenterology.

Hormonal regulation of cholesterol 7 alpha-hydroxylase mRNA levels and transcriptional activity in primary rat hepatocyte cultures.

J. Litz, R. Stravitz, P. Hylemon, 1992, The Journal of biological chemistry.

Effect of cholylsarcosine on hepatic cholesterol and bile acid synthesis and bile secretion in rats.

P. Hylemon, A. Hofmann, W. Pandak, 1992, Gastroenterology.

Transcriptional regulation of cholesterol 7 alpha-hydroxylase mRNA by conjugated bile acids in primary cultures of rat hepatocytes.

R. Stravitz, P. Hylemon, A. Hofmann, 1993, The Journal of biological chemistry.

Expression of sterol 12alpha-hydroxylase alters bile acid pool composition in primary rat hepatocytes and in vivo.

P. Hylemon, G. Gil, W. Pandak, 2001, Gastroenterology.

Absence of negative feedback control of bile acid biosynthesis in cultured rat hepatocytes.

P. Hylemon, P. Guzelian, Z. R. Vlahcevic, 1985, The Journal of biological chemistry.

Receptor-mediated stimulation of taurocholate efflux from the rat hepatocyte and the ex vivo perfused rat liver.

D. Gewirtz, D. Heuman, Z. R. Vlahcevic, 1990, European journal of pharmacology.

Effects of ursodeoxycholic acid, analogues of ursodeoxycholic acid and combination of bile acids on bile acid synthesis in cultured rat hepatocytes.

P. Hylemon, D. Heuman, E. Mosbach, 1987, Biochimica et biophysica acta.

Effects of CYP7A1 overexpression on cholesterol and bile acid homeostasis.

R. Fisher, P. Hylemon, K. Redford, 2001, American journal of physiology. Gastrointestinal and liver physiology.

Hepatocellular protein kinase C activation by bile acids: implications for regulation of cholesterol 7 alpha-hydroxylase.

R. Stravitz, P. Hylemon, Y. Rao, 1996, The American journal of physiology.

Regulation of oxysterol 7α‐hydroxylase (CYP7B1) in primary cultures of rat hepatocytes

P. Hylemon, S. Ren, D. Marques, 2002 .

Regulation of bile acid synthesis. III. Correlation between biliary bile salt hydrophobicity index and the activities of enzymes regulating cholesterol and bile acid synthesis in the rat.

P. Hylemon, D. Heuman, Z. R. Vlahcevic, 1989, Journal of lipid research.

Bile salts in submicellar concentrations promote bidirectional cholesterol transfer (exchange) as a function of their hydrophobicity.

P. Hylemon, D. Heuman, Z. R. Vlahcevic, 1990, Journal of lipid research.

Repression of cholesterol 7 alpha-hydroxylase transcription by bile acids is mediated through protein kinase C in primary cultures of rat hepatocytes.

R. Stravitz, P. Hylemon, Z. R. Vlahcevic, 1995, Journal of lipid research.

Regulation of cholesterol 7 alpha-hydroxylase mRNA and transcriptional activity by taurocholate and cholesterol in the chronic biliary diverted rat.

P. Hylemon, J. Chiang, W. Pandak, 1991, The Journal of biological chemistry.

Regulation of bile acid synthesis. V. Inhibition of conversion of 7-dehydrocholesterol to cholesterol is associated with down-regulation of cholesterol 7 alpha-hydroxylase activity and inhibition of bile acid synthesis.

P. Hylemon, W. Pandak, D. Heuman, 1990, Journal of lipid research.

Induction of sodium-dependent bile acid transporter messenger RNA, protein, and activity in rat ileum by cholic acid.

P. Dawson, R. Stravitz, A. Sanyal, 1997, Gastroenterology.

Bile acid synthesis. VI. Regulation of cholesterol 7 alpha-hydroxylase by taurocholate and mevalonate.

P. Hylemon, J. Chiang, W. Pandak, 1992, Journal of lipid research.

Effect of hydrophobic bile acids on 3-hydroxy-3-methylglutaryl-coenzyme A reductase activity and mRNA levels in the rat.

Z. Beg, P. Hylemon, D. Heuman, 1991, The Journal of biological chemistry.

Effects of perturbations in hepatic free and esterified cholesterol pools on bile acid synthesis, cholesterol 7α-hydroxylase, HMG-CoA reductase, acyl-CoA:Cholesterol acyltransferase and cytosolic cholesteryl ester hydrolase

W. Grogan, D. Heuman, Z. R. Vlahcevic, 1991, Lipids.

Regulation of bile acid synthesis. IV. Interrelationship between cholesterol and bile acid biosynthesis pathways.

P. Hylemon, W. Pandak, D. Heuman, 1990, Journal of lipid research.

A proposed nomenclature for bile acids.

A. Hofmann, J. Sjövall, G. Tint, 1992, Journal of lipid research.

Cholesterol 7 alpha-hydroxylase: evidence for transcriptional regulation by cholesterol or metabolic products of cholesterol in the rat.

P. Hylemon, J. Chiang, W. Pandak, 1993, Journal of lipid research.

Hormonal regulation of cholesterol 7alpha-hydroxylase specific activity, mRNA levels, and transcriptional activity in vivo in the rat.

R. Stravitz, P. Hylemon, J. Chiang, 1997, Journal of lipid research.

Failure of intravenous infusion of taurocholate to down-regulate cholesterol 7 alpha-hydroxylase in rats with biliary fistulas.

P. Hylemon, J. Chiang, W. Pandak, 1995, Gastroenterology.

Post-transcriptional regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase and cholesterol 7 alpha-hydroxylase in rats with subtotal nephrectomy.

W. Pandak, D. Heuman, J. Chan, 1994, Kidney international.

Studies of alteration of hepatic cholesterol metabolism in puromycin-induced nephrotic syndrome in rats.

W. Pandak, D. Heuman, J. Chan, 1993, Kidney international.

Quantitative estimations of the contribution of different bile acid pathways to total bile acid synthesis in the rat.

R. Stravitz, P. Hylemon, W. Pandak, 1997, Gastroenterology.

Regulation of rat hepatic 3 alpha-hydroxysteroid dehydrogenase in vivo and in primary cultures of rat hepatocytes.

R. Stravitz, P. Hylemon, W. Pandak, 1994, Journal of lipid research.

Regulation of oxysterol 7alpha-hydroxylase (CYP7B1) in primary cultures of rat hepatocytes.

P. Hylemon, S. Ren, D. Marques, 2002, Hepatology.