Ans Punt

发表

Evaluation of research activities and research needs to increase the impact and applicability of alternative testing strategies in risk assessment practice.

Bas J Blaauboer, Ans Punt, Marie-Jeanne W A Schiffelers, 2011, Regulatory toxicology and pharmacology : RTP.

Tutorial on physiologically based kinetic modeling in molecular nutrition and food research.

Ans Punt, Ivonne M C M Rietjens, Jochem Louisse, 2011, Molecular nutrition & food research.

Implementation and verification of PBPK modelling codes of TCDD in rats and humans into Berkeley Madonna

Bernadette Ossendorp, Ans Punt, 2018 .

Implementation of (Q)SAR and physiologically-based kinetic (PBK) modeling techniques into a (Q)SAR-PBK approach for predicting dose-response relationships for rat and human and deriving safe exposure

Ans Punt, Marije Strikwold, Ruud Woutersen, 2010 .

Tandem mass spectrometry analysis of N2-(trans-Isoestragol-3'-yl)-2'-deoxyguanosine as a strategy to study species differences in sulfotransferase conversion of the proximate carcinogen 1'-hydroxyestragole.

Benoît Schilter, Ans Punt, Ivonne M C M Rietjens, 2007, Chemical research in toxicology.

Differences in simulated liver concentrations of toxic coumarin metabolites in rats and different human populations evaluated through physiologically based biokinetic (PBBK) modeling.

Ans Punt, Ivonne M C M Rietjens, I. Rietjens, 2008, Toxicology in vitro : an international journal published in association with BIBRA.

In silico methods for physiologically based biokinetic models describing bioactivation and detoxification of coumarin and estragole: implications for risk assessment.

Benoît Schilter, Ans Punt, Gabriele Scholz, 2010, Molecular nutrition & food research.

A physiologically based biodynamic (PBBD) model for estragole DNA binding in rat liver based on in vitro kinetic data and estragole DNA adduct formation in primary hepatocytes.

Alicia Paini, Maricel Marin-Kuan, Benoît Schilter, 2010, Toxicology and applied pharmacology.

Towards harmonization of test methods for in vitro hepatic clearance studies.

Sandra Coecke, Ans Punt, Jochem Louisse, 2019, Toxicology in vitro : an international journal published in association with BIBRA.

A physiologically based biokinetic (PBBK) model for estragole bioactivation and detoxification in rat.

Benoît Schilter, Ans Punt, Ivonne M C M Rietjens, 2008, Toxicology and applied pharmacology.

Integrating in vitro data and physiologically based kinetic (PBK) modelling to assess the in vivo potential developmental toxicity of a series of phenols

Ans Punt, Ivonne M C M Rietjens, Ruud A Woutersen, 2016, Archives of Toxicology.

Effect of combining in vitro estrogenicity data with kinetic characteristics of estrogenic compounds on the in vivo predictive value.

Annemarie P van Wezel, Merijn Schriks, Ans Punt, 2013, Toxicology in vitro : an international journal published in association with BIBRA.

Basil extract inhibits the sulfotransferase mediated formation of DNA adducts of the procarcinogen 1'-hydroxyestragole by rat and human liver S9 homogenates and in HepG2 human hepatoma cells.

Ans Punt, Ivonne M C M Rietjens, Thierry Delatour, 2008, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Non-animal approaches for toxicokinetics in risk evaluations of food chemicals.

Ans Punt, Hans Bouwmeester, H. Bouwmeester, 2017, ALTEX.

Physiologically based biokinetic model of bioactivation and detoxification of the alkenylbenzene methyleugenol in rat.

Ans Punt, Ivonne M C M Rietjens, Jacques Vervoort, 2011, Toxicology in vitro : an international journal published in association with BIBRA.

Evaluation of human interindividual variation in bioactivation of estragole using physiologically based biokinetic modeling.

Benoît Schilter, Ans Punt, Gabriele Scholz, 2010, Toxicological sciences : an official journal of the Society of Toxicology.

Use of Physiologically Based Biokinetic (PBBK) Modeling to Study Estragole Bioactivation and Detoxification in Humans as Compared with Male Rats

Andreas P. Freidig, Alicia Paini, Benoît Schilter, 2009, Toxicological sciences : an official journal of the Society of Toxicology.

Physiologically based biokinetic (PBBK) modeling of safrole bioactivation and detoxification in humans as compared with rats.

Ans Punt, Ivonne M C M Rietjens, P. van Bladeren, 2012, Toxicological sciences : an official journal of the Society of Toxicology.

In vivo validation of DNA adduct formation by estragole in rats predicted by physiologically based biodynamic modelling.

Alicia Paini, Benoît Schilter, Eric Gremaud, 2012, Mutagenesis.

Toxicokinetics in Risk Evaluations

Ans Punt, A. Punt, 2018, Chemical research in toxicology.

Evaluation of Interindividual Human Variation in Bioactivation and DNA Adduct Formation of Estragole in Liver Predicted by Physiologically Based Kinetic/Dynamic and Monte Carlo Modeling.

Alicia Paini, Benoit Schilter, Ans Punt, 2016, Chemical research in toxicology.

Quantitative structure activity relationship studies on the flavonoid mediated inhibition of multidrug resistance proteins 1 and 2.

Mustafa Usta, Ans Punt, Ivonne M C M Rietjens, 2005, Biochemical pharmacology.

Malabaricone C-containing mace extract inhibits safrole bioactivation and DNA adduct formation both in vitro and in vivo.

Alicia Paini, Ans Punt, Ivonne M C M Rietjens, 2014, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Physiologically based kinetic modeling of hesperidin metabolism and its use to predict in vivo effective doses in humans.

Ans Punt, Ivonne M C M Rietjens, I. Rietjens, 2017, Molecular nutrition & food research.