M. Shaldam

发表

Multi-spectroscopic, thermodynamic, and molecular docking/dynamic approaches for characterization of the binding interaction between calf thymus DNA and palbociclib

F. Belal, H. Elmansi, Moataz A. Shaldam, 2022, Scientific Reports.

Applying green analytical chemistry (GAC) for development of stability indicating HPLC method for determining clonazepam and its related substances in pharmaceutical formulations and calculating uncertainty

M. Abdallah, A. Shalaby, M. Abdallah, 2014, Arabian Journal of Chemistry.

Protective Potential of Saussurea costus (Falc.) Lipsch. Roots against Cyclophosphamide-Induced Pulmonary Injury in Rats and Its In Vitro Antiviral Effect

Amal M. Kabbash, H. Fawzy, N. Attallah, 2023, Pharmaceuticals.

Anti-Biofilm and Antibacterial Activities of Cycas media R. Br Secondary Metabolites: In Silico, In Vitro, and In Vivo Approaches

N. Altwaijry, Engy Elekhnawy, I. A. Hussein, 2022, Antibiotics.

A Novel Use of Allopurinol as A Quorum-Sensing Inhibitor in Pseudomonas aeruginosa

Hisham A. Abbas, Mohammed F. Aldawsari, El-Sayed Khafagy, 2021, Antibiotics.

Ketoprofen, piroxicam and indomethacin‐suppressed quorum sensing and virulence factors in Acinetobacter baumannii

Moataz A. Shaldam, Mona I Shaaban, Soha Elshaer, 2022, Journal of applied microbiology.

Bilosomes as Nanoplatform for Oral Delivery and Modulated In Vivo Antimicrobial Activity of Lycopene

Engy Elekhnawy, Walaa A. Negm, I. A. Hussein, 2022, Pharmaceuticals.

The promising anti-virulence activity of candesartan, domperidone, and miconazole on Staphylococcusaureus

Hisham A. Abbas, Amira M. El-Ganiny, Mona A. El-Sayed, 2021, Brazilian Journal of Microbiology.

Discovery of indolinone-bearing benzenesulfonamides as new dual carbonic anhydrase and VEGFR-2 inhibitors possessing anticancer and pro-apoptotic properties.

Tamer M. Ibrahim, C. Supuran, Wagdy M. Eldehna, 2023, European journal of medicinal chemistry.

1,5-Diaryl-1,2,4-triazole Ureas as New SLC-0111 Analogues Endowed with Dual Carbonic Anhydrase and VEGFR-2 Inhibitory Activities.

Tamer M. Ibrahim, C. Supuran, H. Abdel‐Aziz, 2023, Journal of medicinal chemistry.

Development of novel benzofuran-based SLC-0111 analogs as selective cancer-associated carbonic anhydrase isoform IX inhibitors.

Tamer M. Ibrahim, C. Supuran, C. Capasso, 2021, European journal of medicinal chemistry.

Drugs with new lease of life as quorum sensing inhibitors: for combating MDR Acinetobacter baumannii infections

Amira M. El-Ganiny, Moataz A. Shaldam, N. Seleem, 2020, European Journal of Clinical Microbiology & Infectious Diseases.

Nicotinonitrile-derived apoptotic inducers: Design, synthesis, X-ray crystal structure and Pim kinase inhibition.

H. Aoyama, Haytham O. Tawfik, Shaimaa M Aboukhatwa, 2022, Bioorganic chemistry.

In silico screening of potent bioactive compounds from honeybee products against COVID-19 target enzymes

G. Yahya, Yahya Al Naggar, M. Abdel-Daim, 2020, Environmental Science and Pollution Research.

Novel 4-(2-arylidenehydrazineyl)thienopyrimidine derivatives as anticancer EGFR inhibitors: Design, synthesis, biological evaluation, kinome selectivity and in silico insights.

Wagdy M. Eldehna, E. F. Khaleel, R. Badi, 2023, Bioorganic chemistry.

Ligand-Based Design on the Dog-Bone-Shaped BIBR1532 Pharmacophoric Features and Synthesis of Novel Analogues as Promising Telomerase Inhibitors with In Vitro and In Vivo Evaluations.

S. Antar, Mohamed S. Nafie, Ayman Abo Elmaaty, 2022, Journal of medicinal chemistry.

Synthesis, crystallographic, DNA binding, and molecular docking/dynamic studies of a privileged chalcone-sulfonamide hybrid scaffold as a promising anticancer agent

M. Sugiura, F. Belal, H. Elmansi, 2022, Journal of biomolecular structure & dynamics.

Novel 3-(6-methylpyridin-2-yl)coumarin-based chalcones as selective inhibitors of cancer-related carbonic anhydrases IX and XII endowed with anti-proliferative activity

C. Supuran, Wagdy M. Eldehna, A. Nocentini, 2022, Journal of enzyme inhibition and medicinal chemistry.

New Thiazolopyrimidine as anticancer agents: Synthesis, biological evaluation, DNA binding, Molecular modeling and ADMET study.

Ghada S. Hassan, Sara T. A. Al-Rashood, Moataz A. Shaldam, 2020, Bioorganic & medicinal chemistry letters.

Tackling Virulence of Pseudomonas aeruginosa by the Natural Furanone Sotolon

Hisham A. Abbas, Mohammed F. Aldawsari, El-Sayed Khafagy, 2021, Antibiotics.

Bestatin analogs-4-quinolinone hybrids as antileishmanial hits: Design, repurposing rational, synthesis, in vitro and in silico studies.

T. Phan, J. No, Yeon Ju Kim, 2023, European journal of medicinal chemistry.

Synthesis of imidazolidine‐2,4‐dione and 2‐thioxoimidazolidin‐4‐one derivatives as inhibitors of virulence factors production in Pseudomonas aeruginosa

Hisham A. Abbas, Eatedal H. Abdel-Aal, Moataz A. Shaldam, 2020, Archiv der Pharmazie.

Simultaneous Determination of Formoterol Fumarate and Budesonide Epimers in Metered Dose Inhaler Using Ion-Pair Chromatography.

D. El-Sherbiny, D. R. El-wasseef, S. M. El-Ashry, 2017, Journal of chromatographic science.

Novel fused imidazotriazines acting as promising top. II inhibitors and apoptotic inducers with greater selectivity against head and neck tumors: Design, synthesis, and biological assessments.

Hamada S. Abulkhair, A. A. Al-karmalawy, Haytham O. Tawfik, 2023, European journal of medicinal chemistry.

Synthesis, Evaluation of Pharmacological Activity, and Molecular Docking of 1,4-Dihydropyridines as Calcium Antagonists.

M. H. El-Hamamsy, D. Saleh, T. El-Moselhy, 2016, Chemical & pharmaceutical bulletin.

Discovery of sulfonamide-tethered isatin derivatives as novel anticancer agents and VEGFR-2 inhibitors

C. Supuran, A. Angeli, Wagdy M. Eldehna, 2023, Journal of enzyme inhibition and medicinal chemistry.

Metolazone co-crystals-loaded oral fast dissolving films: Design, optimization, and in vivo evaluation

A. Ramadan, Ahmed A. El-Shenawy, Reda A. Mahmoud, 2023, Journal of Drug Delivery Science and Technology.

Sodium Citrate Alleviates Virulence in Pseudomonas aeruginosa

Hisham A. Abbas, T. Ibrahim, El-Sayed Khafagy, 2022, Microorganisms.

1,4-Dihydropyridine Calcium Channel Blockers: Homology Modeling of the Receptor and Assessment of Structure Activity Relationship

M. H. El-Hamamsy, T. El-Moselhy, Moataz A. Shaldam, 2014 .

Lead Optimization of BIBR1591 To Improve Its Telomerase Inhibitory Activity: Design and Synthesis of Novel Four Chemical Series with In Silico, In Vitro, and In Vivo Preclinical Assessments.

Ahmed M. El‐Dessouki, Haytham O. Tawfik, Radwan Alnajjar, 2023, Journal of medicinal chemistry.

Discovery and Mechanistic Studies of Dual-Target Hits for Carbonic Anhydrase IX and VEGFR-2 as Potential Agents for Solid Tumors: X-ray, In Vitro, In Vivo, and In Silico Investigations of Coumarin-Based Thiazoles.

C. Supuran, Wagdy M. Eldehna, Ahmed M. El‐Dessouki, 2024, Journal of medicinal chemistry.

Discovery of Novel Pyridazine-Tethered Sulfonamides as Carbonic Anhydrase II Inhibitors for the Management of Glaucoma.

C. Supuran, Wagdy M. Eldehna, A. Nocentini, 2024, Journal of medicinal chemistry.

Development of new thieno[2,3-d]pyrimidines as dual EGFR and STAT3 inhibitors endowed with anticancer and pro-apoptotic activities.

Wagdy M. Eldehna, R. Badi, E. El-Bastawissy, 2024, Bioorganic chemistry.

Secnidazole Is a Promising Imidazole Mitigator of Serratia marcescens Virulence

Hisham A. Abbas, Hani Asfour, El-Sayed Khafagy, 2021, Microorganisms.

Xylitol Inhibits Growth and Blocks Virulence in Serratia marcescens

Hisham A. Abbas, Wafaa E. Soliman, T. Ibrahim, 2021, Microorganisms.

Study of the binding interaction of salmon sperm DNA with nintedanib, a tyrosine kinase inhibitor using multi-spectroscopic, thermodynamic, and in silico approaches

F. Belal, M. Salim, Moataz A. Shaldam, 2023, Journal of biomolecular structure & dynamics.

A new framework for novel analogues of pazopanib as potent and selective human carbonic anhydrase inhibitors: Design, repurposing rational, synthesis, crystallographic, in vivo and in vitro biological assessments.

C. Supuran, M. Ferraroni, A. Angeli, 2024, European journal of medicinal chemistry.

Discovery of new quinoline derivatives bearing 1-aryl-1,2,3-triazole motif as influenza H1N1 virus neuraminidase inhibitors.

Ahmed Sabt, Wagdy M. Eldehna, E. F. Khaleel, 2024, Bioorganic chemistry.

Fragment-based design and synthesis of coumarin-based thiazoles as dual c-MET/STAT-3 inhibitors for potential antitumor agents.

Mohamed S. Nafie, S. Mohamady, Haytham O. Tawfik, 2024, Bioorganic chemistry.

Unveiling the potential of isatin-grafted phenyl-1,2,3-triazole derivatives as dual VEGFR-2/STAT-3 inhibitors: Design, synthesis and biological assessments.

Wagdy M. Eldehna, Haytham O. Tawfik, E. Elkaeed, 2024, Bioorganic chemistry.

New coumarin linked thiazole derivatives as antimycobacterial agents: Design, synthesis, enoyl acyl carrier protein reductase (InhA) inhibition and molecular modeling.

J. Dziadek, M. Korycka-Machala, Ahmed Sabt, 2024, Bioorganic chemistry.

Novel sulfonamide-tethered Schiff bases as anti-proliferative agents with VEGFR-2 inhibitory activity: Synthesis, biological assessment, and molecular dynamic simulations

C. Supuran, A. Angeli, Wagdy M. Eldehna, 2024, Journal of Molecular Structure.

Rosuvastatin and diosmetin inhibited the HSP70/TLR4 /NF-κB p65/NLRP3 signaling pathways and switched macrophage to M2 phenotype in a rat model of acute kidney injury induced by cisplatin.

N. Altwaijry, I. A. Hussein, Moneerah J. Alqahtani, 2024, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Tailored horseshoe-shaped nicotinonitrile scaffold as dual promising c-Met and Pim-1 inhibitors: Design, synthesis, SAR and in silico study.

Mohamed S. Nafie, S. Mohamady, Haytham O. Tawfik, 2023, Bioorganic chemistry.

Identification of 3‐(5‐cyano‐6‐oxo‐pyridin‐2‐yl)benzenesulfonamides as novel anticancer agents endowed with EGFR inhibitory activity

C. Supuran, A. Angeli, Wagdy M. Eldehna, 2023, Archiv der Pharmazie.

New tilomisole-based benzimidazothiazole derivatives as anti-inflammatory agents: Synthesis, in vivo, in vitro evaluation, and in silico studies.

Ghada S. Hassan, H. Abdel‐Aziz, Mariam A. Ghaly, 2022, Bioorganic chemistry.

Chronotherapeutic neuroprotective effect of verapamil against lipopolysaccharide-induced neuroinflammation in mice through modulation of calcium-dependent genes

Esraa M. Mosalam, Heba R Salem, Amany Said Sallam, 2022, Molecular Medicine.