S. K. Akiyama

发表

Integrin function: molecular hierarchies of cytoskeletal and signaling molecules

K. Yamada, J. Gutkind, S. Akiyama, 1995, The Journal of cell biology.

Analysis of fibronectin receptor function with monoclonal antibodies: roles in cell adhesion, migration, matrix assembly, and cytoskeletal organization

W. T. Chen, K. Yamada, S. Akiyama, 1989, The Journal of cell biology.

Integrins in cell adhesion and signaling.

S. Akiyama, S. K. Akiyama, 1996, Human cell.

Activation of CD4 cells by fibronectin and anti-CD3 antibody. A synergistic effect mediated by the VLA-5 fibronectin receptor complex

C. Morimoto, K. Yamada, S. Akiyama, 1989, The Journal of experimental medicine.

Induction of T cell adhesion to extracellular matrix or endothelial cell ligands by soluble or matrix‐bound interleukin‐7

Kenneth M. Yamada, R. Alon, T. Lapidot, 1997, European journal of immunology.

A Novel Protease-docking Function of Integrin at Invadopodia*

S. Akiyama, S. Mueller, Q. Sang, 1999, The Journal of Biological Chemistry.

Solution structure and dynamics of linked cell attachment modules of mouse fibronectin containing the RGD and synergy regions: comparison with the human fibronectin crystal structure.

S. Aota, D. Torchia, R. Pastor, 1998, Journal of molecular biology.

Cis-polyunsaturated fatty acids stimulate beta1 integrin-mediated adhesion of human breast carcinoma cells to type IV collagen by activating protein kinases C-epsilon and -mu.

K. Olden, F. Wolber, S. Akiyama, 2001, Cancer research.

Recent advances in research on fibronectin and other cell attachment proteins

M. Humphries, K. Olden, K. Yamada, 1985, Journal of cellular biochemistry.

The Interactions of Cells with Extracellular Matrix Components

Kenneth M. Yamada, S. Akiyama, K. Yamada, 1984 .

Positive regulation of cell-cell and cell-substrate adhesion by protein kinase A.

S. Akiyama, J. Whittard, S. K. Akiyama, 2001, Journal of cell science.

Vinexin Forms a Signaling Complex with Sos and Modulates Epidermal Growth Factor-induced c-Jun N-terminal Kinase/Stress-activated Protein Kinase Activities*

S. Aota, K. Yamada, A. Suwa, 1999, The Journal of Biological Chemistry.

Vinexin: A Novel Vinculin-binding Protein with Multiple SH3 Domains Enhances Actin Cytoskeletal Organization

Kenneth M. Yamada, S. Aota, K. Okazaki, 1999, The Journal of cell biology.

A potential marker protease of invasiveness, seprase, is localized on invadopodia of human malignant melanoma cells.

W. T. Chen, T. Kelly, S. Akiyama, 1994, Cancer research.

p38 mitogen-activated protein kinase interacts with vinculin at focal adhesions during fatty acid-stimulated cell adhesion.

K. Olden, John D. Roberts, G. Kissling, 2013, Biochemistry and cell biology = Biochimie et biologie cellulaire.

Collagen, and Laminin in Human Skin Variable Expression in Basal and Squamous Cell Carcinomas

Kenneth M. Yamada, H. Gralnick, H. Larjava, 1989 .

Identification of an alternatively spliced site in human plasma fibronectin that mediates cell type-specific adhesion

M. Humphries, K. Olden, K. Yamada, 1986, The Journal of cell biology.

STRUCTURE AND FUNCTION OF FIBRONECTIN

Kenneth M. Yamada, S. Akiyama, M. Hayashi, 1982 .

The structure of fibronectin and its role in cellular adhesion.

K. Yamada, S. Akiyama, M. Hayashi, 1981, Journal of supramolecular structure and cellular biochemistry.

Human neutrophil adherence to laminin in vitro. Evidence for a distinct neutrophil integrin receptor for laminin

C. Damsky, G. Zimmerman, S. Akiyama, 1990, The Journal of experimental medicine.

Novel function for beta 1 integrins in keratinocyte cell-cell interactions

H. Gralnick, H. Larjava, J. Uitto, 1990, The Journal of cell biology.

Synergistic roles for receptor occupancy and aggregation in integrin transmembrane function

Kenneth M. Yamada, S. Akiyama, S. Miyamoto, 1995, Science.

A Mechanism for Regulation of Melanoma Invasion

Yoshihiko Yamada, M. Nomizu, S. Akiyama, 1996, The Journal of Biological Chemistry.

A two‐domain mechanism for group A streptococcal adherence through protein F to the extracellular matrix.

K. Yamada, E. Hanski, S. Akiyama, 1996, The EMBO journal.

Introduction: adhesion molecules in cancer. Part I.

K. Yamada, S. Akiyama, S. K. Akiyama, 1993, Seminars in cancer biology.

Regulation of cell-substrate adhesion by proteoglycans immobilized on extracellular substrates.

M. Yamagata, K. Yamada, S. Akiyama, 1989, The Journal of biological chemistry.

Altered glycosylation and cell surface expression of beta 1 integrin receptors during keratinocyte activation.

K. Yamada, F. Grinnell, S. Akiyama, 1992, Journal of cell science.

Identification of a novel anti‐integrin monoclonal antibody that recognises a ligand‐induced binding site epitope on the β1 subunit

M. Humphries, A. Mould, A. Garratt, 1995, FEBS letters.

Latex beads as probes of cell surface-extracellular matrix interactions during chondrogenesis: evidence for a role for amino-terminal heparin-binding domain of fibronectin.

S A Newman, S. Newman, S. Akiyama, 1989, Developmental biology.

Matrix-driven translocation: dependence on interaction of amino-terminal domain of fibronectin with heparin-like surface components of cells or particles.

S. Newman, S. Akiyama, D. Frenz, 1987, Proceedings of the National Academy of Sciences of the United States of America.

Cell-surface nucleolin is a signal transducing P-selectin binding protein for human colon carcinoma cells.

E. M. Reyes-Reyes, S. Akiyama, E. Reyes-Reyes, 2008, Experimental cell research.

Neurite extension of chicken peripheral nervous system neurons on fibronectin: relative importance of specific adhesion sites in the central cell-binding domain and the alternatively spliced type III connecting segment

M. Humphries, K. Olden, K. Yamada, 1988, The Journal of cell biology.

Basic fibroblast growth factor release by human coronary artery endothelial cells is enhanced by matrix proteins, 17beta-estradiol, and a PKC signaling pathway.

H. Schnaper, S. Akiyama, M. L. Albuquerque, 1998, Experimental cell research.

BCL2 inhibits Cell Adhesion, Spreading, and Motility by Enhancing Actin Polymerization

Jennifer Y. Zhang, J. French, Hengning Ke, 2010, Cell Research.

Arachidonic Acid Activates Mitogen-activated Protein (MAP) Kinase-activated Protein Kinase 2 and Mediates Adhesion of a Human Breast Carcinoma Cell Line to Collagen Type IV through a p38 MAP Kinase-dependent Pathway*

K. Olden, John D. Roberts, S. Akiyama, 2000, The Journal of Biological Chemistry.

Purification of Vitronectin

S. Akiyama, S. K. Akiyama, 1999, Current protocols in cell biology.

Cell surface receptors for extracellular matrix components.

K. Yamada, S. Akiyama, K. Nagata, 1990, Biochimica et biophysica acta.

Expression and ligand binding of α2β1 integrin on breast carcinoma cells

R. Dickson, S. Akiyama, V. Woods, 1995, Clinical & Experimental Metastasis.

Expression and ligand binding of alpha 2 beta 1 integrin on breast carcinoma cells.

R. Dickson, S. Akiyama, V. Woods, 1995, Clinical & experimental metastasis.

Regulation of Integrin α5β1-Fibronectin Interactions by Divalent Cations

M. Humphries, A. Mould, S. Akiyama, 1995, The Journal of Biological Chemistry.

Regulation of integrin alpha 5 beta 1-fibronectin interactions by divalent cations. Evidence for distinct classes of binding sites for Mn2+, Mg2+, and Ca2+.

M. Humphries, A. Mould, S. Akiyama, 1995, The Journal of biological chemistry.

Analysis of the role of glycosylation of the human fibronectin receptor.

K. Yamada, S. Akiyama, S. Yamada, 1989, The Journal of biological chemistry.

Lysine 63-linked ubiquitination is important for arachidonic acid-induced cellular adhesion and migration.

K. Olden, John D. Roberts, S. Akiyama, 2010, Biochemistry and cell biology = Biochimie et biologie cellulaire.

TNF-alpha binds to the N-terminal domain of fibronectin and augments the beta 1-integrin-mediated adhesion of CD4+ T lymphocytes to the glycoprotein.

R. Alon, K. Yamada, D. Wallach, 1994, Journal of immunology.

Inhibition of binding of fibronectin to matrix assembly sites by anti- integrin (alpha 5 beta 1) antibodies

K. Yamada, D. Mosher, S. Akiyama, 1990, The Journal of cell biology.

Fibronectin and interactions at the cell surface.

K. Olden, K. Yamada, H. Hirano, 1984, Progress in clinical and biological research.

Transmembrane signal transduction by integrin cytoplasmic domains expressed in single-subunit chimeras.

K. Yamada, S. Akiyama, S. Yamada, 1994, The Journal of biological chemistry.

Differences in the biosynthesis and localization of the fibronectin receptor in normal and transformed cultured human cells.

H. Larjava, K. Yamada, S. Akiyama, 1990, Cancer research.

CYLD inhibits melanoma growth and progression through suppression of the JNK/AP-1 and β1-integrin signaling pathways

Jennifer Y. Zhang, C. Augustine, D. Tyler, 2012, The Journal of investigative dermatology.

Localization of integrin receptors for fibronectin, collagen, and laminin in human skin. Variable expression in basal and squamous cell carcinomas.

H. Gralnick, H. Larjava, J. Uitto, 1989, The Journal of clinical investigation.

Transforming growth factor beta stimulates the expression of fibronectin and of both subunits of the human fibronectin receptor by cultured human lung fibroblasts.

W. T. Chen, J. McQuillan, K. Yamada, 1988, The Journal of biological chemistry.

Identification of two distinct regions of the type III connecting segment of human plasma fibronectin that promote cell type-specific adhesion.

M. Humphries, K. Olden, K. Yamada, 1987, The Journal of biological chemistry.

Formation of amyloid-like fibrils by self-association of a partially unfolded fibronectin type III module.

S. Aota, C. Haudenschild, S. Akiyama, 1998, Journal of molecular biology.

Fibronectin and integrins in invasion and metastasis

Kenneth M. Yamada, K. Olden, S. Akiyama, 1995, Cancer and Metastasis Reviews.

Purification of Fibronectin

S. Akiyama, S. K. Akiyama, 2013, Current protocols in cell biology.

Purification of Fibronectin

S. Akiyama, S. K. Akiyama, 1999, Current protocols in cell biology.

Fibronectin structure and function, and its interactions with glycosaminoglycans.

K. Yamada, S. Akiyama, M. Hayashi, 1981, Biochemical Society transactions.

P-selectin activates integrin-mediated colon carcinoma cell adhesion to fibronectin.

John D. Roberts, S. Akiyama, M. D. George, 2006, Experimental cell research.

Activation of Protein Kinase C by Phorbol Esters Modulates α2β1Integrin on MCF-7 Breast Cancer Cells

R. Dickson, Michael D. Johnson, E. Rosfjord, 1999 .

Regulation of fibronectin receptor distribution [published erratum appears in J Cell Biol 1992 Jul;118(2):491]

Kenneth M. Yamada, S. Akiyama, S. LaFlamme, 1992, The Journal of cell biology.

Monoclonal antibody and synthetic peptide inhibitors of human tumor cell migration.

W. T. Chen, H. Gralnick, K. Yamada, 1990, Cancer research.

Human Tumor Cell Migration Monoclonal Antibody and Synthetic Peptide Inhibitors of Updated Version

Kenneth M. Yamada, H. Gralnick, S. Yamada, 2006 .

Identification of an alternatively spliced site in human plasma fibronectin that mediates cell type-specific adhesion

M. Humphries, K. Olden, K. Yamada, 1986, The Journal of cell biology.

The inhibitory anti-beta1 integrin monoclonal antibody 13 recognizes an epitope that is attenuated by ligand occupancy. Evidence for allosteric inhibition of integrin function.

M. Humphries, A. Mould, S. Akiyama, 1996, The Journal of biological chemistry.

The carboxy-terminal extension of the collagen binding domain of fibronectin mediates interaction with a 165 kDa membrane protein involved in odontoblast differentiation.

S. Akiyama, H. Lesot, J. Ruch, 1992, Differentiation; research in biological diversity.

Novel Function for Integrins in Keratinocyte Cell-Cell Interactions

Kenneth M. Yamada, H. Gralnick, H. Larjava, 2002 .

Functional interactions of fibronectin and TNF alpha: a paradigm of physiological linkage between cytokines and extracellular matrix moieties.

A. Miller, K. Yamada, S. Akiyama, 1994, Cell adhesion and communication.

Function and receptor specificity of a minimal 20 kilodalton cell adhesive fragment of fibronectin.

S. Aota, K. Yamada, S. Akiyama, 1995, Cell adhesion and communication.

Substrate-specific binding of the amino terminus of fibronectin to an integrin complex in focal adhesions.

D. M. Peters, B. Dzamba, S. Akiyama, 1994, The Journal of biological chemistry.

Functional analysis of cell adhesion: quantitation of cell-matrix attachment.

S. Akiyama, S. K. Akiyama, 2002, Methods in cell biology.

Characterization of a 140-kD avian cell surface antigen as a fibronectin-binding molecule

K. Yamada, S. Akiyama, S. Yamada, 1986, The Journal of cell biology.

Bioadhesion and cell behavior

S. Akiyama, S. LaFlamme, S. K. Akiyama, 1994 .

Rgd-independent Cell Adhesion to the Carboxy-terminal Hepadn-binding Fragment of Fibronectin Involves Heparin-dependent and -independent Activities

K. Olden, L. Furcht, M. Chelberg, 1990 .

The interaction of fibronectin fragments with fibroblastic cells.

K. Yamada, S. Akiyama, T. Hasegawa, 1985, The Journal of biological chemistry.

The interaction of plasma fibronectin with fibroblastic cells in suspension.

K. Yamada, S. Akiyama, S. K. Akiyama, 1985, The Journal of biological chemistry.

Analysis of fibronectin receptor function with monoclonal antibodies: roles in cell adhesion, migration, matrix assembly, and cytoskeletal organization

K. Yamada, S. Yamada, Wen‐Tien Chen, 1989, The Journal of cell biology.

Activation of β1 Integrins Induces Cell–Cell Adhesion

S. Akiyama, J. Whittard, S. K. Akiyama, 2001 .

Anti‐integrin antibodies induce type IV collagenase expression in keratinocytes

H. Birkedal‐Hansen, H. Larjava, T. Salo, 1993, Journal of cellular physiology.

Fibroblast‐mediated collagen gel contraction does not require fibronectin‐α5β1 integrin interaction

S. Akiyama, J. Tomasek, S. K. Akiyama, 1992 .

Fibronectin in evolution: presence in invertebrates and isolation from Microciona prolifera.

S. Akiyama, M. D. Johnson, S. K. Akiyama, 1983, Comparative biochemistry and physiology. B, Comparative biochemistry.

Inhibition of Binding of Fibronectin to Matrix Assembly Sites by Anti-Integrin Antibodies

Kenneth M. Yamada, S. Akiyama, F. J. Fogerty, 2002 .

Aberrant N-Glycosylation of β1 Integrin Causes Reduced α5β1 Integrin Clustering and Stimulates Cell Migration

S. Akiyama, M. Pierce, Intaek Lee, 2002 .

Integrin Clustering and Stimulates Cell Migration

M. Pierce, Intaek Lee, M. Kamar, 2002 .

Latex beads as probes of cell surface-extracellular matrix interactions during chondrogenesis: evidence for a role for amino-terminal heparin-binding domain of fibronectin.

D. Frenz, D. Paulsen, S. Newman, 1989, Developmental biology.

Monoclonal antibody characterization of two distant sites required for function of the central cell-binding domain of fibronectin in cell adhesion, cell migration, and matrix assembly

S. Aota, K. Olden, K. Yamada, 1991, The Journal of cell biology.

TNF-alpha associated with fibronectin enhances phorbol myristate acetate- or antigen-mediated integrin-dependent adhesion of CD4+ T cells via protein tyrosine phosphorylation.

S. Miron, R. Alon, K. Yamada, 1994, Journal of immunology.

Swainsonine stimulation of the proliferation and colony forming activity of murine bone marrow.

K. Olden, S. Akiyama, K. Grzegorzewski, 1991, Cancer communications.

Swainsonine modulation of protein kinase C activity in murine peritoneal macrophages.

K. Olden, K. Grzegorzewski, S. White, 1990, Cancer communications.

Induction of macrophage tumoricidal activity, major histocompatibility complex class II antigen (Iak) expression, and interleukin-1 production by swainsonine.

K. Olden, S. Sharrow, K. Grzegorzewski, 1989, Cancer communications.

BCL2 interaction with actin in vitro may inhibit cell motility by enhancing actin polymerization

Jennifer Y. Zhang, J. French, Hengning Ke, 2011, Cell adhesion & migration.

Regulation of Fibronectin Receptor Distribution

K. Yamada, S. Akiyama, S. LaFlamme, 2002 .

Comparisons of evolutionarily distinct fibronectins: Evidence for the origin of plasma and fibroblast cellular fibronectins from a single gene

K. Yamada, S. Akiyama, S. K. Akiyama, 1985, Journal of cellular biochemistry.

Aberrant N-glycosylation of beta1 integrin causes reduced alpha5beta1 integrin clustering and stimulates cell migration.

S. Akiyama, M. Pierce, Intaek Lee, 2002, Cancer research.

A mechanism for regulation of melanoma invasion. Ligation of alpha6beta1 integrin by laminin G peptides.

W. T. Chen, Y. Yamada, M. Nomizu, 1996, The Journal of biological chemistry.

Structural and functional comparisons of chicken and human cellular fibronectins.

B. Bernard, K. Olden, K. Yamada, 1984, The Journal of biological chemistry.