E. Gibbs

发表

4-Azidophlorizin, a high affinity probe and photoaffinity label for the glucose transporter in brush border membranes.

G. Semenza, E. M. Gibbs, B. Reber, 1982, Biochimica et biophysica acta.

Possibility of Distinct Insulin-Signaling Pathways Beyond Phosphatidylinositol 3-Kinase–Mediating Glucose Transport and Lipogenesis

E. M. Gibbs, R. W. Stevenson, D. Kreutter, 1998, Diabetes.

The Antihyperglycemic Agent Englitazone Prevents the Defect in Glucose Transport in Rats Fed a High-Fat Diet

R. McPherson, E. M. Gibbs, A. Swick, 1996, Diabetes.

The glucose transporter in 3T3-L1 adipocytes is phosphorylated in response to phorbol ester but not in response to insulin.

G. Lienhard, W. J. Allard, E. M. Gibbs, 1986, The Journal of biological chemistry.

Altered metabolism causes cardiac dysfunction in perfused hearts from diabetic (db/db) mice.

D. Severson, E. M. Gibbs, E M Gibbs, 2000, American journal of physiology. Endocrinology and metabolism.

Nitric Oxide Stimulates Skeletal Muscle Glucose Transport Through a Calcium/Contraction– and Phosphatidylinositol-3-Kinase–Independent Pathway

G. Etgen, E. M. Gibbs, D. Fryburg, 1997, Diabetes.

Effects of overexpression of human GLUT4 gene on maternal diabetes and fetal growth in spontaneous gestational diabetic C57BLKS/J Lepr(db/+) mice.

J. Friedman, T. Ishizuka, S. Liu, 1999, Diabetes.

Glycemic improvement in diabetic db/db mice by overexpression of the human insulin-regulatable glucose transporter (GLUT4).

J. Pessin, J. Stock, J. Mcneish, 1995, The Journal of clinical investigation.

Enhanced peripheral glucose utilization in transgenic mice expressing the human GLUT4 gene.

R. McPherson, J. Treadway, J. Pessin, 1994, The Journal of biological chemistry.

Transgenic mice expressing the human GLUT4/muscle-fat facilitative glucose transporter protein exhibit efficient glycemic control.

R. McPherson, J. Treadway, J. Pessin, 1993, Proceedings of the National Academy of Sciences of the United States of America.

Endogenous effectors of human liver glycogen phosphorylase modulate effects of indole-site inhibitors.

V. L. Rath, F. Nuttall, Carolyn B Levy, 2005, American journal of physiology. Endocrinology and metabolism.

Glucose metabolism in perfused mouse hearts overexpressing human GLUT-4 glucose transporter.

D. Severson, E. M. Gibbs, D. Belke, 2001, American journal of physiology. Endocrinology and metabolism.

Discovery of PF-04620110, a Potent, Selective, and Orally Bioavailable Inhibitor of DGAT-1.

Eliot Sugarman, Angel Guzman-Perez, G. S. Walker, 2011, ACS medicinal chemistry letters.

Hypoglycemic Activity of a Series of α-Alkylthio and α-Alkoxy Carboxylic Acids Related to Ciglitazone

B. Hulin, L. S. Newton, P. Genereux, 1996 .

Human Small Intestine Facilitative Fructose/Glucose Transporter (GLUT5) Is Also Present in Insulin-Responsive Tissues and Brain: Investigation of Biochemical Characteristics and Translocation

B. Kahn, P. Shepherd, G. Gould, 1992, Diabetes.

244. Sulphur derivatives of thiazoles

F. A. Robinson, E. Gibbs, 1945 .

Fluid‐phase endocytosis by isolated rat adipocytes

G. Lienhard, E. M. Gibbs, Gustav E. Lienhard, 1984, Journal of cellular physiology.

Insulinlike Activity of New Antidiabetic Agent CP 68722 in 3T3-L1 Adipocytes

E. M. Gibbs, R. W. Stevenson, D. Kreutter, 1990, Diabetes.

Acute Effects of Atypical Antipsychotics on Whole-Body Insulin Resistance in Rats: Implications for Adverse Metabolic Effects

K. Houseknecht, W. Zavadoski, E. M. Gibbs, 2007, Neuropsychopharmacology.

Effect of the Activation of Phosphatidylinositol 3-Kinase by a Thiophosphotyrosine Peptide on Glucose Transport in 3T3-L1 Adipocytes (*)

G. Lienhard, E. M. Gibbs, D. Singleton, 1995, The Journal of Biological Chemistry.

Distribution of GLUT3 glucose transporter protein in human tissues.

B. Kahn, P. Shepherd, G. Gould, 1992, Biochemical and biophysical research communications.

Analysis of the glucose transporter content of islet cell lines: implications for glucose-stimulated insulin release.

S. Baldwin, G. Gould, E. M. Gibbs, 1992, Cellular signalling.

Establishment of Correlation between in Vitro Enzyme Binding Potency and in Vivo Pharmacological Activity: Application to Liver Glycogen Phosphorylase a Inhibitors

R. McPherson, J. Treadway, E. M. Gibbs, 2006, Journal of Pharmacology and Experimental Therapeutics.

Actions of Novel Antidiabetic Agent Englitazone in Hyperglycemic Hyperinsulinemic ob/ob Mice

R. McPherson, R. Volkmann, E. M. Gibbs, 1990, Diabetes.

Expression of the brain-type glucose transporter is restricted to brain and neuronal cells in mice

B. Kahn, P. Shepherd, G. Gould, 1992, Diabetologia.

Glucose utilization and glucose transporter proteins GLUT-1 and GLUT-3 in brains of diabetic (db/db) mice.

S. Vannucci, I. Simpson, E. Gibbs, 1997, The American journal of physiology.

Insulin-induced translocation of glucose transporters from post-Golgi compartments to the plasma membrane of 3T3-L1 adipocytes

J. Slot, H. Geuze, G. Lienhard, 1988, The Journal of cell biology.

Structure-activity analysis of the purine binding site of human liver glycogen phosphorylase.

David G Myszka, Dennis E Danley, R. Fletterick, 2002, Chemistry & biology.

Human liver glycogen phosphorylase inhibitors bind at a new allosteric site.

V. L. Rath, M. Ammirati, D. Danley, 2000, Chemistry & biology.

Effect of phenylarsine oxide on fluid phase endocytosis: Further evidence for activation of the glucose transporter

M. Lane, E. M. Gibbs, S. Frost, 1989, Journal of cellular physiology.

Insulin-induced translocation of glucose transporters to the plasma membrane precedes full stimulation of hexose transport.

G. Lienhard, G. Gould, E. M. Gibbs, 1988, Biochemistry.

Insulin-stimulated translocation of the HepG2/erythrocyte-type glucose transporter expressed in 3T3-L1 adipocytes.

D. James, G. Lienhard, M. Mueckler, 1989, The Journal of biological chemistry.

Identification of a novel glucose transporter-like protein-GLUT-12.

D. James, M. Carty, W. Soeller, 2002, American journal of physiology. Endocrinology and metabolism.

Phorbol ester only partially mimics the effects of insulin on glucose transport and glucose-transporter distribution in 3T3-L1 adipocytes.

G. Gould, E. M. Gibbs, G. Holman, 1991, The Biochemical journal.

Nitric oxide increases cyclic GMP levels, AMP-activated protein kinase (AMPK)α1-specific activity and glucose transport in human skeletal muscle

A. Deshmukh, H. Koistinen, J. Zierath, 2010, Diabetologia.

GLUT4 overexpression in db/db mice dose-dependently ameliorates diabetes but is not a lifelong cure.

T. Reynolds, S. Cushman, J. Brozinick, 2001, Diabetes.

Inhibitory effects of antipsychotics on carbachol-enhanced insulin secretion from perifused rat islets: role of muscarinic antagonism in antipsychotic-induced diabetes and hyperglycemia.

Anne W. Schmidt, J. Treadway, E. M. Gibbs, 2005, Diabetes.

The glucose transporter in human fibroblasts is phosphorylated in response to phorbol ester but not in response to growth factors.

G. Lienhard, W. J. Allard, L. Witters, 1987, Biochimica et biophysica acta.

Germline manipulation of glucose homeostasis via alteration of glucose transporter levels in skeletal muscle.

W. Soeller, M. Mueckler, J. Holloszy, 1993, The Journal of biological chemistry.

The PPAR-γ Agonist, Darglitazone, Restores Acute Inflammatory Responses to Cerebral Hypoxia–Ischemia in the Diabetic ob/ob Mouse

S. Vannucci, I. Simpson, R. Kumari, 2010, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Pharmacological inhibition to examine the role of

S. Watkins, Tara B. Manion, Dawn Mather, 2013 .

Dual-action hypoglycemic and hypocholesterolemic agents that inhibit glycogen phosphorylase and lanosterol demethylase Published, JLR Papers in Press, December 16, 2004. DOI 10.1194/jlr.M400436-JLR200

J. Treadway, E. M. Gibbs, E. Sugarman, 2005, Journal of Lipid Research.

5-Chloroindoloyl glycine amide inhibitors of glycogen phosphorylase: synthesis, in vitro, in vivo, and X-ray crystallographic characterization.

V. L. Rath, S. Wright, D. Hageman, 2005, Bioorganic & medicinal chemistry letters.

Indole-2-carboxamide inhibitors of human liver glycogen phosphorylase.

R. McPherson, J. Treadway, E. M. Gibbs, 1998, Journal of medicinal chemistry.

Insulin-sensitive regulation of glucose transport and GLUT4 translocation in skeletal muscle of GLUT1 transgenic mice.

G. Etgen, W. Zavadoski, E. M. Gibbs, 1999, The Biochemical journal.

Modeling the Mechanism of Action of a DGAT1 Inhibitor Using a Causal Reasoning Platform

Nigel Greene, Daniel Ziemek, Ranjit Randhawa, 2011, PloS one.

Characterization of vesicles containing insulin-responsive intracellular glucose transporters isolated from 3T3-L1 adipocytes by an improved procedure.

G. Lienhard, S. Baldwin, G. Gould, 1988, Biochimica et biophysica acta.

Substituted dihydrobenzopyran and dihydrobenzofuran thiazolidine-2,4-diones as hypoglycemic agents.

R. Volkmann, E. M. Gibbs, J. Eggler, 1991, Journal of medicinal chemistry.

Phloretinyl-3'-benzylazide: a high affinity probe for the sugar transporter in human erythrocytes. I. Hexose transport inhibition and photolabeling of mutarotase.

E. M. Gibbs, D. Diedrich, F. Fannin, 1981, Biochimica et biophysica acta.

The Glitazone Family of Antidiabetic Agents

E. M. Gibbs, B. Hulin, P. A. McCarthy, 1996, Current Pharmaceutical Design.

Growth factor-induced stimulation of hexose transport in 3T3-L1 adipocytes: evidence that insulin-induced translocation of GLUT4 is independent of activation of MAP kinase.

I. Campbell, R. Plevin, T. Jess, 1994, Cellular signalling.