S. Krüger

发表

Involvement of hMSH6 in the development of hereditary and sporadic colorectal cancer revealed by immunostaining is based on germline mutations, but rarely on somatic inactivation

H. Schackert, F. Theissig, H. Saeger, 2002, International journal of cancer.

Modulation of alpha smooth muscle actin and desmin expression in perisinusoidal cells of normal and diseased human livers.

H. Denk, G. Gabbiani, S. Krüger, 1991, The American journal of pathology.

Ki-67 Protein Concentrations in Urothelial Bladder Car- Cinomas Are Related to Ki-67-specific Rna Concentra- Tions

G. Sczakiel, S. Krüger, I. Kausch, 2004 .

ROS1 rearrangements in lung adenocarcinoma: prognostic impact, therapeutic options and genetic variability

C. Kropf-Sanchen, Y. Ko, J. Wolf, 2015, Oncotarget.

Colitis cystica profunda and giant inflammatory pseudopolyp in Crohn’s disease

A. Feller, F. Noack, M. Birth, 2005, International Journal of Colorectal Disease.

Clinicopathological Characteristics of RET Rearranged Lung Cancer in European Patients

L. Bubendorf, R. Hein, W. Engel-Riedel, 2016, Journal of Thoracic Oncology.

Aneuploidy-Associated Gene Expression Signatures Characterize Malignant Transformation in Ulcerative Colitis

T. Ried, S. Hautaniemi, K. Nousiainen, 2013, Inflammatory bowel diseases.

Fibrosarcoma associated with a benign cystic teratoma of the ovary.

A. Feller, H. Schmidt, F. Rath, 2002, Gynecologic oncology.

Spectrum and frequencies of mutations in MSH2 and MLH1 identified in 1,721 German families suspected of hereditary nonpolyposis colorectal cancer

M. Kloor, M. Loeffler, J. Gebert, 2005, International journal of cancer.

Prognostic significance of a grading system considering tumor heterogeneity in muscle-invasive urothelial carcinoma of the urinary bladder

C. Thorns, S. Krüger, A. Böhle, 2004, International Urology and Nephrology.

Impact of TP53 mutation status on systemic treatment outcome in ALK-rearranged non-small-cell lung cancer

Roman K. Thomas, T. Zander, D. Seidel, 2018, Annals of oncology : official journal of the European Society for Medical Oncology.

HER2 overexpression in muscle‐invasive urothelial carcinoma of the bladder: Prognostic implications

A. Feller, S. Krüger, A. Böhle, 2002, International journal of cancer.

A polymerase chain reaction-based semiquantitative assessment of malignant melanoma cells in peripheral blood.

C. Scheibenbogen, P. Brossart, U. Keilholz, 1995, Cancer research.

Nintedanib + docetaxel in lung adenocarcinoma patients (pts) following treatment with immune checkpoint inhibitors (ICIs): Updated efficacy and safety results of the ongoing non-interventional study (NIS) VARGADO (NCT02392455).

R. Kaiser, J. Atz, C. Grohé, 2020 .

Late onset Li-Fraumeni Syndrome with bilateral breast cancer and other malignancies: case report and review of the literature

K. Friedrich, M. Krause, B. Thamm, 2012, BMC Cancer.

Prognostic value of MCM2 immunoreactivity in stage T1 transitional cell carcinoma of the bladder.

A. Feller, C. Thorns, S. Krüger, 2003, European urology.

Overexpression of c-erbB-2 oncoprotein in muscle-invasive bladder carcinoma: relationship with gene amplification, clinicopathological parameters and prognostic outcome.

A. Feller, S. Krüger, A. Böhle, 2002, International journal of oncology.

Sequential proteome alterations during genesis and progression of colon cancer

T. Ried, D. Hirschberg, C. Palmberg, 2004, Cellular and Molecular Life Sciences CMLS.

Ten novel MSH2 and MLH1 germline mutations in families with HNPCC

D. Aust, H. Schackert, H. Saeger, 2004, Human mutation.

Expression of KIT (CD117) in Renal Cell Carcinoma and Renal Oncocytoma

K. Sotlar, S. Krüger, I. Kausch, 2005, Oncology.

Seven novel MLH1 and MSH2 germline mutations in hereditary nonpolyposis colorectal cancer

H. Schackert, F. Theissig, H. Saeger, 2002, Human mutation.

The p53 codon 72 variation is associated with the age of onset of hereditary non-polyposis colorectal cancer (HNPCC)

M. von Knebel Doeberitz, K. Schulmann, C. Engel, 2005, Journal of Medical Genetics.

Identification of six novel MSH2 and MLH1 germline mutations in HNPCC

D. Aust, H. Schackert, F. Theissig, 2003, Human mutation.

The additive effect of p53 Arg72Pro and RNASEL Arg462Gln genotypes on age of disease onset in Lynch syndrome patients with pathogenic germline mutations in MSH2 or MLH1.

M. von Knebel Doeberitz, C. Engel, H. Schackert, 2007, Cancer letters.

Arg462Gln sequence variation in the prostate-cancer-susceptibility gene RNASEL and age of onset of hereditary non-polyposis colorectal cancer: a case-control study.

M. von Knebel Doeberitz, C. Engel, J. Rüschoff, 2005, The Lancet. Oncology.

The additive effect of p 53 Arg 72 Pro and RNASEL Arg 462 Gln genotypes on age of disease onset in Lynch syndrome patients with pathogenic germline mutations in MSH 2 or MLH 1

C. Engel, H. Schackert, S. Krüger, 2007 .

Arg 462 Gln sequence variation in the prostate-cancer-susceptibility gene RNASEL and age of onset of hereditary non-polyposis colorectal cancer : a case-control study

C. Engel, J. Rüschoff, S. Krüger, 2022 .

Primary Malignant Melanoma of the Small Bowel a Case Report and Review of the Literature

A. Feller, S. Krüger, F. Noack, 2005, Tumori.

Reply to Inokuchi et al

H. Schackert, G. Ehninger, A. Hochhaus, 2006, Leukemia.

Ten recently identified associations between nsSNPs and colorectal cancer could not be replicated in German families.

M. Kloor, R. Houlston, K. Hemminki, 2008, Cancer letters.

The gene expression signature of genomic instability in breast cancer is an independent predictor of clinical outcome

Sampsa Hautaniemi, Thomas Ried, Stefan Krüger, 2009, International journal of cancer.

Expression of C-reactive protein by renal cell carcinomas and unaffected surrounding renal tissue.

S. Krüger, D. Jocham, W. Jabs, 2005, Kidney international.

Analysis of the base excision repair genes MTH1, OGG1 and MUTYH in patients with squamous oral carcinomas.

I. König, A. Ziegler, H. Schackert, 2007, Oral oncology.

N-acetyltransferase (NAT) 2 acetylator status and age of onset in patients with hereditary nonpolyposis colorectal cancer (HNPCC).

M. von Knebel Doeberitz, C. Engel, J. Rüschoff, 2006, Cancer letters.

Mlh1-deficient Colorectal Cancer and Is Associated with Loss of Msh3 Protein Expression Is Frequent in Cited Articles Citing Articles E-mail Alerts Loss of Msh3 Protein Expression Is Frequent in Mlh1-deficient Colorectal Cancer and Is Associated with Disease Progression 1

H. Schackert, F. Theissig, H. Saeger, 2004 .

Pronounced chromosomal instability and multiple gene amplifications characterize ulcerative colitis-associated colorectal carcinomas.

T. Ried, H. Bruch, G. Auer, 2003, Cancer genetics and cytogenetics.

Numerical aberrations of chromosome 17 and the 9p21 locus are independent predictors of tumor recurrence in non-invasive transitional cell carcinoma of the urinary bladder.

A. Feller, S. Krüger, A. Böhle, 2003, International journal of oncology.

Homozygous PMS2 germline mutations in two families with early-onset haematological malignancy, brain tumours, HNPCC-associated tumours, and signs of neurofibromatosis type 1

S. Boué, H. Schackert, R. Büttner, 2008, European Journal of Human Genetics.

Afatinib as first-line treatment in patients with EGFR-mutated non-small cell lung cancer in routine clinical practice

J. Ficker, C. Kortsik, S. Krüger, 2021, Therapeutic advances in medical oncology.

MET Amplification Status in Therapy-Naïve Adeno- and Squamous Cell Carcinomas of the Lung

T. Zander, Y. Ko, K. Hekmat, 2014, Clinical Cancer Research.

Aneuploidy characterizes adjacent non-malignant mucosa of ulcerative colitis-associated but not sporadic colorectal carcinomas: a matched-pair analysis

S. Freitag-Wolf, H. Bruch, J. Habermann, 2013, Scandinavian journal of gastroenterology.

Lower incidence of colorectal cancer and later age of disease onset in 27 families with pathogenic MSH6 germline mutations compared with families with MLH1 or MSH2 mutations: the German Hereditary Nonpolyposis Colorectal Cancer Consortium.

M. von Knebel Doeberitz, M. Loeffler, J. Gebert, 2004, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Eight novel MSH6 germline mutations in patients with familial and nonfamilial colorectal cancer selected by loss of protein expression in tumor tissue

C. Sutter, G. Evans, J. Gebert, 2004, Human mutation.

Loss of MSH3 Protein Expression Is Frequent in MLH1-Deficient Colorectal Cancer and Is Associated with Disease Progression 1

Stefan Krüger, Franz Theissig, Giancarlo Marra, 2004, Cancer Research.

P16 immunoreactivity is an independent predictor of tumor progression in minimally invasive urothelial bladder carcinoma.

A. Feller, S. Krüger, I. Kausch, 2005, European urology.

Expression of cancer-testis antigen CT7 (MAGE-C1) in breast cancer: An immunohistochemical study with emphasis on prognostic utility

A. Feller, S. Krüger, M. Friedrich, 2008, Pathology & Oncology Research.

Intensified Screening Program for Women with Hereditary Predisposition to Develop Breast Cancer - Our Study Results and Current Knowledge in the Literature

K. Friedrich, M. Laniado, K. Kast, 2009 .

Genotype-phenotype comparison of German MLH1 and MSH2 mutation carriers clinically affected with Lynch syndrome: a report by the German HNPCC Consortium.

M. Kloor, M. Loeffler, J. Gebert, 2006, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Hypothesis: Possible role of retinoic acid therapy in patients with biallelic mismatch repair gene defects

G. Plotz, W. Henn, R. Buettner, 2008, European Journal of Pediatrics.

Genomic instability and oncogene amplifications in colorectal adenomas predict recurrence and synchronous carcinoma

T. Ried, S. Freitag-Wolf, K. Heselmeyer-Haddad, 2011, Modern Pathology.

Stage‐specific alterations of the genome, transcriptome, and proteome during colorectal carcinogenesis

E. Korn, T. Ried, L. McShane, 2007, Genes, chromosomes & cancer.

TCF-3, 4 protein expression correlates with β-catenin expression in MSS and MSI-H colorectal cancer from HNPCC patients but not in sporadic colorectal cancers

H. Schackert, S. Krüger, P. Baláž, 2010, International Journal of Colorectal Disease.

Timing and targeting of cell-based VEGF165 gene expression in ischemic tissue.

T. Aach, G. Middeler, A. Bader, 2009, The Journal of surgical research.

Chondrolipoma of the hand: a case report.

A. Feller, S. Krüger, B. Kisse, 2004, Acta orthopaedica Belgica.

Papillary Urothelial Bladder Carcinoma Associated with Osteoclast-Like Giant Cells

A. Feller, S. Krüger, I. Kausch, 2005, International Urology and Nephrology.

Histologic tumor growth pattern is significantly associated with disease-related survival in muscle-invasive transitional cell carcinoma of the urinary bladder.

A. Feller, S. Krüger, A. Böhle, 2004, Oncology reports.

Prevention and treatment of peritoneal carcinomatosis in experimental investigations with CPT-11 and oxaliplatin

H. Lippert, C. Boltze, W. Halangk, 2002, Anti-cancer drugs.

HNPCC-associated small bowel cancer: clinical and molecular characteristics.

K. Schulmann, W. Schmiegel, C. Engel, 2005, Gastroenterology.

Genomic rearrangements in MSH2, MLH1 or MSH6 are rare in HNPCC patients carrying point mutations.

C. Engel, H. Schackert, H. Saeger, 2007, Cancer letters.

Aneuploidy-Associated Gene Expression Signatures Characterize Malignant Transformation in Ulcerative Colitis

T. Ried, S. Hautaniemi, K. Nousiainen, 2013, Inflammatory bowel diseases.

Ulcerative colitis and colorectal carcinoma: DNA-profile, laminin-5 gamma2 chain and cyclin A expression as early markers for risk assessment.

H. Bruch, G. Auer, K. Tryggvason, 2001, Scandinavian journal of gastroenterology.

Protein expression and gene copy number analysis of topoisomerase 2alpha, HER2 and P53 in minimally invasive urothelial carcinoma of the urinary bladder--a multitissue array study with prognostic implications.

A. Feller, S. Krüger, I. Kausch, 2005, Anticancer research.

MET Amplification Status in Therapy-Naïve Adeno- and Squamous Cell Carcinomas of the Lung

T. Zander, Y. Ko, K. Hekmat, 2014, Clinical Cancer Research.

Significant damage of the conduction system during cardioplegic arrest is due to necrosis not apoptosis.

A. Feller, S. Krüger, H. Sievers, 2004, European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.

Mutational status of KIT and PDGFRA and expression of PDGFRA are not associated with prognosis after curative resection of primary gastrointestinal stromal tumors (GISTs)

H. Schackert, H. Saeger, G. Baretton, 2011, Journal of surgical oncology.

Absence of association between cyclin D1 (CCND1) G870A polymorphism and age of onset in hereditary nonpolyposis colorectal cancer.

C. Engel, J. Rüschoff, H. Schackert, 2006, Cancer letters.

Inhibition of Ki‐67 in a renal cell carcinoma severe combined immunodeficiency disease mouse model is associated with induction of apoptosis and tumour growth inhibition

G. Sczakiel, S. Krüger, D. Jocham, 2005, BJU international.