Cyrille C Thinnes

发表

Integrated Analyses of Microbiome and Longitudinal Metabolome Data Reveal Microbial-Host Interactions on Sulfur Metabolism in Parkinson’s Disease

Ronan M. T. Fleming, R. Fleming, R. Krüger, 2019, Cell reports.

Genome-Scale Metabolic Modeling of the Human Microbiome in the Era of Personalized Medicine.

I. Thiele, A. Heinken, J. Hertel, 2021, Annual review of microbiology.

Targeting histone lysine demethylases — Progress, challenges, and the future

C. Schofield, R. Chowdhury, A. Kawamura, 2014, Biochimica et biophysica acta.

Parkinson’s disease-associated alterations of the gut microbiome predict disease-relevant changes in metabolic functions

Ronan M. T. Fleming, Maike K. Aurich, P. May, 2020, BMC Biology.

Parkinson’s disease-associated alterations of the gut microbiome can invoke disease-relevant metabolic changes

R. Krüger, I. Thiele, F. Betsou, 2019, bioRxiv.

Therapeutic targeting of oxygen-sensing prolyl hydroxylases abrogates ATF4-dependent neuronal death and improves outcomes after brain hemorrhage in several rodent models

Giovanni Coppola, Christopher J. Schofield, Sama F. Sleiman, 2016, Science Translational Medicine.

5-Carboxy-8-hydroxyquinoline is a Broad Spectrum 2-Oxoglutarate Oxygenase Inhibitor which Causes Iron Translocation.

R. Klose, W. Yue, P. Ratcliffe, 2013, Chemical science.

Structure of the Ribosomal Oxygenase OGFOD1 Provides Insights into the Regio- and Stereoselectivity of Prolyl Hydroxylases

C. Schofield, M. McDonough, W. Aik, 2015, Structure.

Structure-activity relationships and colorimetric properties of specific probes for the putative cancer biomarker human arylamine N-acetyltransferase 1.

G. Wynne, A. Russell, E. Sim, 2014, Bioorganic & medicinal chemistry.

A Novel Color Change Mechanism for Breast Cancer Biomarker Detection: Naphthoquinones as Specific Ligands of Human Arylamine N-Acetyltransferase 1

A. Russell, E. Sim, J. Dairou, 2013, PloS one.

5-Carboxy-8-hydroxyquinoline is a Broad Spectrum 2-Oxoglutarate Oxygenase Inhibitor which Causes Iron Translocation.

R. Klose, W. Yue, P. Ratcliffe, 2013, Chemical science.

Therapeutic targeting of oxygen-sensing prolyl hydroxylases abrogates ATF4-dependent neuronal death and improves outcomes after brain hemorrhage in several rodent models

Sama F. Sleiman, C. Culmsee, G. Ming, 2016, Science Translational Medicine.

Glucose Metabolism and Oxygen Availability Govern Reactivation of the Latent Human Retrovirus HTLV-1

C. Schofield, J. McCullagh, C. Bangham, 2017, Cell chemical biology.

Betti reaction enables efficient synthesis of 8-hydroxyquinoline inhibitors of 2-oxoglutarate oxygenases.

S. Müller, P. Ratcliffe, P. Brennan, 2015, Chemical communications.

Selective Inhibitors of a Human Prolyl Hydroxylase (OGFOD1) Involved in Ribosomal Decoding

U. Oppermann, C. Schofield, A. Tumber, 2019, Chemistry.

Complement C1q is hydroxylated by collagen prolyl 4 hydroxylase and is sensitive to off-target inhibition by prolyl hydroxylase domain inhibitors that stabilize hypoxia-inducible factor

P. Maxwell, S. Kiriakidis, C. Schofield, 2017, Kidney international.