W. Hong

W. Hong, W. Hittelman, D. Shin, 1994, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.

Multi-region exome sequencing reveals genomic evolution from preneoplasia to lung adenocarcinoma

K. Ashizawa, Xin Hu, P. Scheet, 2019, Nature Communications.

All-trans-Retinoic Acid Inhibits Jun N-Terminal Kinase by Increasing Dual-Specificity Phosphatase Activity

W. Hong, D. Mangelsdorf, J. Kurie, 1999, Molecular and Cellular Biology.

Reduction to homozygosity at the SIS/PDGF-2 locus in human mesenchymal tumors.

W. Hong, R. Ferrell, D. Shin, 1988, Biochemical and biophysical research communications.

DPC4, a candidate tumor suppressor gene, is altered infrequently in head and neck squamous cell carcinoma.

R. Lotan, W. Hong, L. Mao, 1996, Cancer research.

Treatment and Prevention of Intraepithelial Neoplasia: An Important Target for Accelerated New Agent Development: Recommendations of the American Association for Cancer Research Task Force on the Treatment and Prevention of Intraepithelial Neoplasia

M. Sporn, D. Alberts, S. Lam, 2002 .

Treatment and Prevention of Intraepithelial Neoplasia : An Important Target for Accelerated New Agent Development Recommendations of the American Association for Cancer Research Task Force on the Treatment and Prevention of Intraepithelial Neoplasia 1

M. Sporn, D. Alberts, S. Lam, 2002 .

Reduced DNA repair capacity in lung cancer patients.

M. Spitz, W. Hong, Q. Wei, 1996, Cancer research.

A Novel Derivative of the Natural Agent Deguelin for Cancer Chemoprevention and Therapy

Gordon Mills, Yoo-Shin Kim, Woo-Young Kim, 2008, Cancer Prevention Research.

Structural basis for depletion of heat shock protein 90 client proteins by deguelin.

W. Hong, Hyun-Ju Park, J. Myers, 2007, Journal of the National Cancer Institute.

Genetic Variants in Inflammation-Related Genes Are Associated with Radiation-Induced Toxicity Following Treatment for Non-Small Cell Lung Cancer

Joe Y. Chang, M. Spitz, J. Minna, 2010, PloS one.

Concomitant targeting of the mTOR/MAPK pathways: novel therapeutic strategy in subsets of RICTOR/KRAS-altered non-small cell lung cancer

James X. Sun, Jing Wang, J. Minna, 2018, Oncotarget.

Co-occurring genomic alterations define major subsets of KRAS-mutant lung adenocarcinoma with distinct biology, immune profiles, and therapeutic vulnerabilities.

Michael Peyton, Humam Kadara, Murim Choi, 2015, Cancer discovery.

Cyclin D1 and p16 alterations in advanced premalignant lesions of the upper aerodigestive tract: role in response to chemoprevention and cancer development.

W. Hong, A. El‐Naggar, L. Mao, 2001, Clinical cancer research : an official journal of the American Association for Cancer Research.

Cyclin D 1 and p 16 Alterations in Advanced Premalignant Lesions of the Upper Aerodigestive Tract : Role in Response to Chemoprevention and Cancer Development 1

Diane D. Liu, W. Hong, A. El‐Naggar, 2001 .

Identification of three distinct tumor suppressor loci on the short arm of chromosome 9 in small cell lung cancer.

J. Minna, W. Hong, L. Mao, 1997, Cancer research.

Frequent microsatellite alterations at chromosomes 9p21 and 3p14 in oral premalignant lesions and their value in cancer risk assessment

S. Lippman, W. Hong, L. Mao, 1996, Nature Medicine.

Frequent inactivation of p16INK4a in oral premalignant lesions

S. Lippman, R. Lotan, W. Hong, 1997, Oncogene.

Integrative proteomic and transcriptomic analysis provides evidence for TrkB (NTRK2) as a therapeutic target in combination with tyrosine kinase inhibitors for non-small cell lung cancer

Jing Wang, W. Hong, I. Wistuba, 2018, Oncotarget.

Benzo[a]pyrene diol epoxide-induced 3p21.3 aberrations and genetic predisposition to lung cancer.

M. Spitz, J. Minna, W. Hong, 1998, Cancer research.

Elevated PDGFRB gene copy number gain is prognostic for improved survival outcomes in resected malignant pleural mesothelioma.

W. Hong, I. Wistuba, J. Lee, 2014, Annals of diagnostic pathology.

Visualization of the timing of gene amplification during multistep head and neck tumorigenesis.

W. Hong, M. Tainsky, W. Hittelman, 2000, Cancer research.

Repair of tobacco carcinogen-induced DNA adducts and lung cancer risk: a molecular epidemiologic study.

M. Spitz, W. Hong, Q. Wei, 2000, Journal of the National Cancer Institute.

Epirubicin: a review of the pharmacology, clinical activity, and adverse effects of an adriamycin analogue.

R. J. Cersosimo, W. Hong, W K Hong, 1986, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Induction of Fas expression and augmentation of Fas/Fas ligand-mediated apoptosis by the synthetic retinoid CD437 in human lung cancer cells.

W. Hong, R. Lotan, S. Y. Sun, 2000, Cancer research.

Molecular and cellular biomarkers for field cancerization and multistep process in head and neck tumorigenesis

W. Hong, D. Shin, V. Papadimitrakopoulou, 1996, Cancer and Metastasis Reviews.

Cancer prevention science and practice.

S. Lippman, W. Hong, W. Hong, 2002, Cancer research.

Association between glutathione S‐transferase π polymorphisms and survival in patients with advanced nonsmall cell lung carcinoma

Joe Y. Chang, M. Spitz, W. Hong, 2006, Cancer.

Hypermethylation of the death-associated protein (DAP) kinase promoter and aggressiveness in stage I non-small-cell lung cancer.

F. Khuri, W. Hong, J. Lee, 2000, Journal of the National Cancer Institute.

Adenovirus-mediated p53 gene transfer in sequence with cisplatin to tumors of patients with non-small-cell lung cancer.

F. Khuri, J. Roth, J. Lee, 2000, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Retrovirus–mediated wild–type P53 gene transfer to tumors of patients with lung cancer.

W. Hong, J. Roth, J. Lee, 1996, Nature Medicine.

Localization of chromosome 8p regions involved in early tumorigenesis of oral and laryngeal squamous carcinoma

W. Hong, J. Batsakis, J. Kagan, 1998, Oncogene.

Induction chemotherapy plus radiation compared with surgery plus radiation in patients with advanced laryngeal cancer.

W. Hong, G. Laramore, W. Henderson, 1991, The New England journal of medicine.

Frequent abnormalities of FHIT, a candidate tumor suppressor gene, in head and neck cancer cell lines.

R. Lotan, W. Hong, L. Mao, 1996, Cancer research.

A phase I/II study of neoadjuvant chemotherapy followed by radiation with boost chemotherapy for advanced T-stage nasopharyngeal carcinoma.

A. Garden, K. Ang, F. Khuri, 2005, International journal of radiation oncology, biology, physics.

Effectiveness of combined induction chemotherapy and radiotherapy in advanced nasopharyngeal carcinoma.

R. Weber, W. Hong, L. Peters, 1993, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Plasma levels of insulin-like growth factor-I and lung cancer risk: a case-control analysis.

M. Spitz, W. Hong, Xifeng Wu, 1999, Journal of the National Cancer Institute.

Epidermal growth factor receptor-targeted therapy with C225 and cisplatin in patients with head and neck cancer.

F. Khuri, W. Hong, R. Perez-soler, 2001, Clinical cancer research : an official journal of the American Association for Cancer Research.

Phase II trial of paclitaxel, ifosfamide, and cisplatin in patients with recurrent head and neck squamous cell carcinoma.

K. Ang, S. Lippman, F. Khuri, 1998, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

A phase II study of ifosfamide in recurrent squamous cell carcinoma of the head and neck.

S. Lippman, W. Hong, I. Dimery, 1996, American journal of clinical oncology.

Overview of combined modality therapies for head and neck cancer.

W. Hong, I. Dimery, Isaiah W. Dimery, 1993, Journal of the National Cancer Institute.

Prevention of second primary tumors with isotretinoin in squamous-cell carcinoma of the head and neck.

L J Peters, J S Lee, S. Lippman, 1990, The New England journal of medicine.

Comparison of low-dose isotretinoin with beta carotene to prevent oral carcinogenesis.

R. Weber, S. Lippman, J. Lee, 1993, The New England journal of medicine.

Higher potency of N-(4-hydroxyphenyl)retinamide than all-trans-retinoic acid in induction of apoptosis in non-small cell lung cancer cell lines.

W. Hong, J. Kurie, C. Zou, 1998, Clinical cancer research : an official journal of the American Association for Cancer Research.

Differential effects of synthetic nuclear retinoid receptor-selective retinoids on the growth of human non-small cell lung carcinoma cells.

R. Lotan, W. Hong, Shi-Yong Sun, 1997, Cancer research.

A Phase II Study of Lonafarnib (SCH66336) in Patients With Chemorefractory, Advanced Squamous Cell Carcinoma of the Head and Neck

Edward S. Kim, F. Khuri, W. Hong, 2009, American journal of clinical oncology.

Differential expression profiling of head and neck squamous carcinoma: significance in their phenotypic and biological classification

W. Hong, J. Lee, G. Clayman, 2002, Oncogene.

VEGF/VEGFR-2 Upregulates EZH2 Expression in Lung Adenocarcinoma Cells and EZH2 Depletion Enhances the Response to Platinum-Based and VEGFR-2–Targeted Therapy

K. Coombes, Jing Wang, J. Minna, 2014, Clinical Cancer Research.

Biology of Human Tumors VEGF / VEGFR-2 Upregulates EZH 2 Expression in Lung Adenocarcinoma Cells and EZH 2 Depletion Enhances the Response to Platinum-Based and VEGFR-2 – Targeted Therapy

Milind B. Suraokar, K. Coombes, Jing Wang, 2014 .

Phase I/II trial evaluating the anti-vascular endothelial growth factor monoclonal antibody bevacizumab in combination with the HER-1/epidermal growth factor receptor tyrosine kinase inhibitor erlotinib for patients with recurrent non-small-cell lung cancer.

Edward S. Kim, Diane D. Liu, W. Hong, 2005, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Selective oral epidermal growth factor receptor tyrosine kinase inhibitor ZD1839 is generally well-tolerated and has activity in non-small-cell lung cancer and other solid tumors: results of a phase I trial.

Roy S Herbst, W. Hong, J. Baselga, 2002, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Reduced DNA repair capacity in head and neck cancer patients.

M. Spitz, W. Hong, Q. Wei, 1998, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.

Telomere dysfunction: a potential cancer predisposition factor.

M. Spitz, W. Hong, Xifeng Wu, 2003, Journal of the National Cancer Institute.

The role of induction chemotherapy for organ preservation in laryngeal carcinoma.

W. Hong, I. Dimery, R. Byers, 1990, Cancer treatment and research.

Functional outcomes following treatment for advanced laryngeal cancer. Part I--Voice preservation in advanced laryngeal cancer. Part II--Laryngectomy rehabilitation: the state of the art in the VA System. Research Speech-Language Pathologists. Department of Veterans Affairs Laryngeal Cancer Study Gr

W. Hong, G. Wolf, S. Fisher, 1998, The Annals of otology, rhinology & laryngology. Supplement.

Larynx Preservation Using Induction Chemotherapy plus Radiation Therapy as an Alternative to Laryngectomy in Advanced Head and Neck Cancer A Long‐Term Follow‐up Report

W. Hong, S. Zeitels, P. Calarese, 1991, American journal of clinical oncology.

Phase II multicenter study of the epidermal growth factor receptor antibody cetuximab and cisplatin for recurrent and refractory squamous cell carcinoma of the head and neck.

W. Hong, R. Herbst, E. Vokes, 2005, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Hypermethylation of the death-associated protein kinase promoter attenuates the sensitivity to TRAIL-induced apoptosis in human non-small cell lung cancer cells.

Li Mao, Weiguo Wu, Ignacio I Wistuba, 2004, Molecular cancer research : MCR.

Hypermethylation of the Death-Associated Protein Kinase Promoter Attenuates the Sensitivity to Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand-Induced Apoptosis in Human Non–Small Cell Lung Cancer Cells

W. Hong, I. Wistuba, Shi-Yong Sun, 2004, Molecular Cancer Research.

Mediation of N-(4-hydoxyphenyl)retinamide-induced apoptosis in human cancer cells by different mechanisms.

S. Lippman, R. Lotan, W. Hong, 1999, Cancer research.

Frequent loss of imprinting at the IGF2 and H19 genes in head and neck squamous carcinoma

W. Hong, A. El‐Naggar, G. Clayman, 1999, Oncogene.

Clonal genetic alterations in the lungs of current and former smokers.

J S Lee, S. Lippman, F. Khuri, 1997, Journal of the National Cancer Institute.

Phase II and biologic study of interferon alfa, retinoic acid, and cisplatin in advanced squamous skin cancer.

Diane D. Liu, S. Lippman, F. Khuri, 2002, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Mechanisms underlying lack of insulin-like growth factor-binding protein-3 expression in non-small-cell lung cancer

F. Khuri, W. Hong, Y. Chang, 2004, Oncogene.

Correlation between insulin-like growth factor-binding protein-3 promoter methylation and prognosis of patients with stage I non-small cell lung cancer.

Li Mao, Fadlo R Khuri, Diane D. Liu, 2002, Clinical cancer research : an official journal of the American Association for Cancer Research.

Clinical significance of insulin-like growth factor-binding protein-3 expression in stage I non-small cell lung cancer.

Diane D. Liu, F. Khuri, W. Hong, 2002, Clinical cancer research : an official journal of the American Association for Cancer Research.

Genomic heterogeneity of multiple synchronous lung cancer

Dongmei Lin, Li Zhang, John V Heymach, 2016, Nature Communications.

CXCR2 expression in tumor cells is a poor prognostic factor and promotes invasion and metastasis in lung adenocarcinoma.

John V Heymach, Young-Ho Ahn, Roy S Herbst, 2013, Cancer research.

The natural history of cervical intraepithelial neoplasia: an argument for intermediate endpoint biomarkers.

W. Hong, W. Hittelman, R. Lotan, 1994, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.

Assessing environmental and occupational risk factors for lung cancer in Mexican–Americans

M. Spitz, W. Hong, Q. Dong, 2010, Cancer Causes & Control.

Development and Validation of a Lung Cancer Risk Prediction Model for African-Americans

M. Spitz, W. Hong, Q. Dong, 2008, Cancer Prevention Research.

Perspectives in Cancer Research Cancer Prevention Science and Practice 1

S. Lippman, W. Hong, W. Hong, 2002 .

The BATTLE-2 Study: A Biomarker-Integrated Targeted Therapy Study in Previously Treated Patients With Advanced Non-Small-Cell Lung Cancer.

Li Shen, John V Heymach, Kevin R Coombes, 2016, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Value of p16INK4a and RASSF1A Promoter Hypermethylation in Prognosis of Patients with Resectable Non–Small Cell Lung Cancer

Diane D. Liu, W. Hong, J. Lee, 2004, Clinical Cancer Research.

A novel polymorphism in human cytosine DNA-methyltransferase-3B promoter is associated with an increased risk of lung cancer.

Hongbing Shen, M. Spitz, W. Hong, 2002, Cancer research.

Clinicopathologic Characteristics of the EGFR Gene Mutation in Non–small Cell Lung Cancer

M. Spitz, W. Hong, J. Roth, 2006, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

Increased polysomies of chromosomes 7 and 17 during head and neck multistage tumorigenesis.

W. Hong, W. Hittelman, D. Shin, 1993, Cancer research.

Chemotherapy in head and neck cancer.

W. Hong, M. Kies, N. Levitan, 1983, The New England journal of medicine.

Novel Susceptibility Loci for Second Primary Tumors/Recurrence in Head and Neck Cancer Patients: Large-Scale Evaluation of Genetic Variants

Jian Gu, J Jack Lee, Yuanqing Ye, 2009, Cancer Prevention Research.

Implication of p53 in growth arrest and apoptosis induced by the synthetic retinoid CD437 in human lung cancer cells.

R. Lotan, W. Hong, Shi-Yong Sun, 1999, Cancer research.

Implication of p 53 in Growth Arrest and Apoptosis Induced by the Synthetic Retinoid CD 437 in Human Lung Cancer Cells 1

R. Lotan, W. Hong, Shi-Yong Sun, 1999 .

A randomized trial comparing perioperative chemotherapy and surgery with surgery alone in resectable stage IIIA non-small-cell lung cancer.

J. Roth, R. Komaki, E. Atkinson, 1994, Journal of the National Cancer Institute.

Expression of vascular endothelial growth factor and microvessel density in head and neck tumorigenesis.

W. Hong, J. Lee, W. Hittelman, 2000, Clinical cancer research : an official journal of the American Association for Cancer Research.

Aberrant promoter methylation of multiple genes in bronchial brush samples from former cigarette smokers.

Diane D. Liu, W. Hong, J. Lee, 2002, Cancer research.

Stress hormones promote EGFR inhibitor resistance in NSCLC: Implications for combinations with β-blockers

Edward S. Kim, Diane D. Liu, Jing Wang, 2017, Science Translational Medicine.

Randomized phase III intergroup trial of isotretinoin to prevent second primary tumors in stage I non-small-cell lung cancer.

S. Lippman, F. Khuri, R. Lotan, 2001, Journal of the National Cancer Institute.

Anti-retinoic acid (RA) antibody binding to human premalignant oral lesions, which occurs less frequently than binding to normal tissue, increases after 13-cis-RA treatment in vivo and is related to RA receptor beta expression.

S. Lippman, R. Lotan, W. Hong, 1995, Cancer research.

Impact of Smoking Cessation on Global Gene Expression in the Bronchial Epithelium of Chronic Smokers

Li Mao, J Jack Lee, Li Zhang, 2005, Cancer Prevention Research.

Fingerprinting the circulating repertoire of antibodies from cancer patients

Kim-Anh Do, Christopher J. Logothetis, Massimo Cristofanilli, 2003, Nature Biotechnology.

Effects of deguelin on the phosphatidylinositol 3-kinase/Akt pathway and apoptosis in premalignant human bronchial epithelial cells.

R. Lotan, W. Hong, J. Pezzuto, 2003, Journal of the National Cancer Institute.

p53 Genotypes and Haplotypes Associated With Lung Cancer Susceptibility and Ethnicity.

M. Spitz, S. Shete, W. Hong, 2002, Journal of the National Cancer Institute.

Clinical and Biomarker Outcomes of the Phase II Vandetanib Study from the BATTLE Trial

Edward S. Kim, S. Lippman, W. Hong, 2013, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

Retinoid refractoriness occurs during lung carcinogenesis despite functional retinoid receptors.

R. Lotan, W. Hong, J. Nesbitt, 1995, Cancer research.

New Directions in Lung Cancer: Chemoprevention

F. Khuri, Jin Soo Lee, W. Hong, 1996 .

Differential responses of normal, premalignant, and malignant human bronchial epithelial cells to receptor-selective retinoids.

R. Lotan, W. Hong, J. Kurie, 1999, Clinical cancer research : an official journal of the American Association for Cancer Research.

Adenovirus-mediated p53 gene transfer in patients with advanced recurrent head and neck squamous cell carcinoma.

S. Lippman, W. Hong, J. Roth, 1998, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Cellular and humoral immune responses to adenovirus and p53 protein antigens in patients following intratumoral injection of an adenovirus vector expressing wild-type p53 (Ad-p53)

F. Khuri, W. Hong, J. Roth, 2000, Cancer Gene Therapy.

Biologic correlates of a biochemoprevention trial in advanced upper aerodigestive tract premalignant lesions.

Diane D. Liu, W. Hong, J. Lee, 2002, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.

Cancer prevention by delay. Commentary re: J. A. O'Shaughnessy et al., Treatment and Prevention of Intraepithelial Neoplasia: An Important Target for Accelerated New Agent Development. Clin. Cancer Res., 8: 314-346, 2002.

S. Lippman, W. Hong, W. Hong, 2002, Clinical cancer research : an official journal of the American Association for Cancer Research.

The impact of smoking status, disease stage, and index tumor site on second primary tumor incidence and tumor recurrence in the head and neck retinoid chemoprevention trial.

Edward S. Kim, S. Lippman, F. Khuri, 2001, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.

Combined interferon-alfa, 13-cis-retinoic acid, and alpha-tocopherol in locally advanced head and neck squamous cell carcinoma: novel bioadjuvant phase II trial.

Dan Liu, A. Garden, K. Ang, 2001, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Identification of retinamides that are more potent than N-(4-hydroxyphenyl)retinamide in inhibiting growth and inducing apoptosis of human head and neck and lung cancer cells.

V. Steele, S. Lippman, R. Lotan, 2001, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.

p53 protein accumulation and genomic instability in head and neck multistep tumorigenesis.

S. Lippman, W. Hong, J. Lee, 2001, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.

Biochemoprevention for dysplastic lesions of the upper aerodigestive tract.

S. Lippman, A. Gillenwater, W. Hong, 1999, Archives of otolaryngology--head & neck surgery.

Dysregulated cyclin D1 expression early in head and neck tumorigenesis: in vivo evidence for an association with subsequent gene amplification

W. Hong, Xia Li, W. Hittelman, 1998, Oncogene.

Accumulation of p53 protein and retinoic acid receptor beta in retinoid chemoprevention.

S. Lippman, R. Lotan, W. Hong, 1997, Clinical cancer research : an official journal of the American Association for Cancer Research.

Telomerase activity in head and neck squamous cell carcinoma and adjacent tissues.

S. Lippman, R. Lotan, W. Hong, 1996, Cancer research.

p53 Expression: Predicting Recurrence and Second Primary Tumors in Head and Neck Squamous Cell Carcinoma

S. Lippman, W. Hong, J. Lee, 1996 .

Mutagen sensitivity as a risk factor for second malignant tumors following malignancies of the upper aerodigestive tract.

M. Spitz, W. Hong, C. Amos, 1994, Journal of the National Cancer Institute.

Differential expression of nuclear retinoid receptors in normal, premalignant, and malignant head and neck tissues.

R. Lotan, W. Hong, D. Shin, 1994, Cancer research.

Prevention of second primary tumors with isotretinoin in patients with squamous cell carcinoma of the head and neck: long-term follow-up.

S. Lippman, W. Hong, T. Pajak, 1994, Journal of the National Cancer Institute.

Chemoprevention of aerodigestive tract cancers.

Edward S. Kim, F. Khuri, W. Hong, 2002, Annual review of medicine.

Treatment and prevention of intraepithelial neoplasia: an important target for accelerated new agent development.

M. Sporn, D. Alberts, S. Lam, 2002, Clinical cancer research : an official journal of the American Association for Cancer Research.

p53 and retinoid chemoprevention of oral carcinogenesis.

S. Lippman, R. Lotan, J. Lee, 1995, Cancer research.

Suppression of epidermal growth factor receptor, mitogen-activated protein kinase, and Pak1 pathways and invasiveness of human cutaneous squamous cancer cells by the tyrosine kinase inhibitor ZD1839 (Iressa).

C. J. Barnes, W. Hong, M. Mandal, 2003 .

Phase I study of recombinant human endostatin in patients with advanced solid tumors.

L. Ellis, K. Hess, W. Hong, 2002, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Phase II study of a multidisciplinary approach with induction chemotherapy, followed by surgical resection, radiation therapy, and consolidation chemotherapy for unresectable malignant thymomas: final report.

Edward S. Kim, F. Khuri, W. Hong, 2004, Lung cancer.

Long-term follow-up of patients enrolled in a randomized trial comparing perioperative chemotherapy and surgery with surgery alone in resectable stage IIIA non-small-cell lung cancer.

J. Roth, R. Komaki, E. Atkinson, 1998, Lung cancer.

Multiregion gene expression profiling reveals heterogeneity in molecular subtypes and immunotherapy response signatures in lung cancer

P. A. Futreal, Jing Wang, W. Hong, 2018, Modern Pathology.

In Support of a Patient-Driven Initiative and Petition to Lower the High Price of Cancer Drugs.

James Allison, Stephen Forman, Massimo Cristofanilli, 2015, Mayo Clinic proceedings.

Chemoprevention of respiratory tract cancer.

F. Khuri, W. Hong, J. Kurie, 1997, Hematology/oncology clinics of North America.

Randomized placebo-controlled trial of isotretinoin in chemoprevention of bronchial squamous metaplasia.

S. Lippman, J. Lee, W. Hong, 1994, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Discordant p53 gene mutations in primary head and neck cancers and corresponding second primary cancers of the upper aerodigestive tract.

W. Hong, T. Mukhopadhyay, A. Casson, 1993, Cancer research.

Phase II study of taxol in patients with untreated advanced non-small-cell lung cancer.

R. Winn, F. Fossella, D. Shin, 1993, Journal of the National Cancer Institute.

Implication of mitochondria-derived reactive oxygen species, cytochrome C and caspase-3 in N-(4-Hydroxyphenyl)retinamide-induced apoptosis in cervical carcinoma cells

R. Lotan, W. Hong, N. Oridate, 1999, Oncogene.

the Synthetic Retinoid CD 437 in Human Lung Cancer Cells Implication of p 53 in Growth Arrest and Apoptosis Induced by Updated

R. Lotan, W. Hong, Shi-Yong Sun, 1999 .

Edward S. Kim, M. Spitz, S. Lippman, 2010, Carcinogenesis.

A Five-Gene and Corresponding Protein Signature for Stage-I Lung Adenocarcinoma Prognosis

John D. Minna, Humam Kadara, Edward S. Kim, 2010, Clinical Cancer Research.

All-trans retinoic acid converts E2F into a transcriptional suppressor and inhibits the growth of normal human bronchial epithelial cells through a retinoic acid receptor- dependent signaling pathway.

W. Hong, M. Andreeff, J. Kurie, 1998, The Journal of clinical investigation.

Dietary intake of isothiocyanates: evidence of a joint effect with glutathione S-transferase polymorphisms in lung cancer risk.

M. Spitz, W. Hong, Xifeng Wu, 2000, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.

A randomized clinical trial of 4-hydroxyphenylretinamide for high-grade squamous intraepithelial lesions of the cervix.

S. Lippman, R. Lotan, W. Hong, 2001, Clinical cancer research : an official journal of the American Association for Cancer Research.

Gene Expression Signature–Based Prognostic Risk Score in Gastric Cancer

Jae Yong Cho, Jae Ho Cheong, Eun Sung Park, 2011, Clinical Cancer Research.

Survivin expression in normal human bronchial epithelial cells: an early and critical step in tumorigenesis induced by tobacco exposure.

W. Hong, L. Mao, Ho-Yyoung Lee, 2008, Carcinogenesis.

Implication of AMP-activated protein kinase and Akt-regulated survivin in lung cancer chemopreventive activities of deguelin.

W. Hong, I. Wistuba, C. Behrens, 2007, Cancer research.

Association between the V109G Polymorphism of the p27 Gene and the Risk and Progression of Oral Squamous Cell Carcinoma

M. Spitz, W. Hong, Q. Wei, 2004, Clinical Cancer Research.

Association between the V 109 G Polymorphism of the p 27 Gene and the Risk and Progression of Oral Squamous Cell Carcinoma

M. Spitz, W. Hong, Q. Wei, 2004 .

An Attenuated Adenovirus , ONYX-015 , As Mouthwash Therapy for Premal ignant

C. Rudin, S. Lippman, W. Hong, 2003 .

Overexpressed Activated Retinoid X Receptors Can Mediate Growth Inhibitory Effects of Retinoids in Human Carcinoma Cells*

R. Lotan, W. Hong, M. Dawson, 1998, The Journal of Biological Chemistry.

Prognostic impact of insulin receptor expression on survival of patients with nonsmall cell lung cancer

Edward S. Kim, Diane D. Liu, S. Lippman, 2012, Cancer.

Sex Determining Region Y-Box 2 (SOX2) Is a Potential Cell-Lineage Gene Highly Expressed in the Pathogenesis of Squamous Cell Carcinomas of the Lung

John D. Minna, Humam Kadara, Yang Xie, 2010, PloS one.

Elevated epithelial insulin-like growth factor expression is a risk factor for lung cancer development.

Edward S. Kim, Y. Miller, S. Lippman, 2009, Cancer research.

Chemoprevention of Cancer

Edward S. Kim, W. Hong, A. Tsao, 2004, CA: a cancer journal for clinicians.

Immune-Modulation by Epidermal Growth Factor Receptor Inhibitors: Implication on Anti-Tumor Immunity in Lung Cancer

W. Hong, R. Perez-soler, C. Haymaker, 2016, PloS one.

Patterns of relapse in locally advanced head and neck cancer patients who achieved complete remission after combined modality therapy

S. Shapshay, W. Hong, M. Strong, 1985, Cancer.

Activation of insulin-like growth factor 1 receptor in patients with non-small cell lung cancer

Edward S. Kim, Diane D. Liu, S. Lippman, 2015, Oncotarget.

Proteomics-based identification of proteins secreted in apical surface fluid of squamous metaplastic human tracheobronchial epithelial cells cultured by three-dimensional organotypic air-liquid interface method.

R. Lotan, W. Hong, I. Wistuba, 2007, Cancer research.

Phase I Study of the Farnesyltransferase Inhibitor Lonafarnib with Paclitaxel in Solid Tumors

Edward S. Kim, W. R. Bishop, P. Thall, 2004, Clinical Cancer Research.

Posttranslational mechanisms contribute to the suppression of specific cyclin:CDK complexes by all-trans retinoic acid in human bronchial epithelial cells.

W. Hong, J. Kurie, G. Walsh, 1999, Cancer research.

Clinical Outcomes and Biomarker Profiles of Elderly Pretreated NSCLC Patients from the BATTLE Trial

J Jack Lee, Edward S. Kim, Ignacio Wistuba, 2012, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

Abnormalities of the TITF-1 Lineage-Specific Oncogene in NSCLC: Implications in Lung Cancer Pathogenesis and Prognosis

Humam Kadara, Diane D. Liu, Diane D Liu, 2011, Clinical Cancer Research.

Adding Erlotinib to Chemoradiation Improves Overall Survival but not Progression-Free Survival in Stage III Non-Small-Cell Lung Cancer

Diane D. Liu, W. Hong, I. Wistuba, 2015, International journal of radiation oncology, biology, physics.

Polymorphism of DNA ligase I and risk of lung cancer--a case-control analysis.

Hongbing Shen, M. Spitz, W. Hong, 2002, Lung cancer.

Augmentation of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis by the synthetic retinoid 6-[3-(1-adamantyl)-4-hydroxyphenyl]-2-naphthalene carboxylic acid (CD437) through up-regulation of TRAIL receptors in human lung cancer cells.

W. Hong, R. Lotan, S. Y. Sun, 2000, Cancer research.

Loss of Fhit is frequent in stage I non-small cell lung cancer and in the lungs of chronic smokers.

F. Khuri, W. Hong, L. Mao, 1999, Cancer research.

Head and Neck Cancer: A Multidisciplinary Approach

W. Hong, L. Harrison, R. Sessions, 2013 .

Differential induction of apoptosis by all-trans-retinoic acid and N-(4-hydroxyphenyl)retinamide in human head and neck squamous cell carcinoma cell lines.

R. Lotan, W. Hong, D. Lotan, 1996, Clinical cancer research : an official journal of the American Association for Cancer Research.

Activation of melanoma antigen tumor antigens occurs early in lung carcinogenesis.

W. Hong, R. Morice, J. Soria, 2001, Cancer research.

Strategy and planning for chemopreventive drug development: Clinical development plans II

G. Omenn, V. Steele, W. Hong, 1996, Journal of cellular biochemistry. Supplement.

Treatment of former smokers with 9-cis-retinoic acid reverses loss of retinoic acid receptor-beta expression in the bronchial epithelium: results from a randomized placebo-controlled trial.

Diane D. Liu, J. Minna, F. Khuri, 2003, Journal of the National Cancer Institute.

Phenotype and genotype of advanced premalignant head and neck lesions after chemopreventive therapy.

S. Lippman, W. Hong, J. Lee, 1998, Journal of the National Cancer Institute.

Case-control study of the D2 dopamine receptor gene and smoking status in lung cancer patients.

M. Spitz, W. Hong, Xifeng Wu, 1998, Journal of the National Cancer Institute.

Identification of Insulin-Like Growth Factor Binding Protein-3 as a Farnesyl Transferase Inhibitor SCH66336-Induced Negative Regulator of Angiogenesis in Head and Neck Squamous Cell Carcinoma

F. Khuri, W. Hong, P. Cohen, 2006, Clinical Cancer Research.

Overexpression of cyclin B1 in early-stage non-small cell lung cancer and its clinical implication.

F. Khuri, W. Hong, J. Soria, 2000, Cancer research.

Insulin-like growth factor binding protein-3 inhibits the growth of non-small cell lung cancer.

Pinchas Cohen, W. Hong, J. Kurie, 2002, Cancer research.

Insulin-like growth factor binding protein-6 activates programmed cell death in non-small cell lung cancer cells

W. Hong, J. Roth, J. Kurie, 2000, Oncogene.

The BATTLE to Personalize Lung Cancer Prevention through Reverse Migration

Edward S. Kim, W. Hong, I. Wistuba, 2011, Cancer Prevention Research.

Biological Activity of Celecoxib in the Bronchial Epithelium of Current and Former Smokers

Edward S. Kim, Diane D. Liu, R. Lotan, 2010, Cancer Prevention Research.

Genome-wide association study of survival in non-small cell lung cancer patients receiving platinum-based chemotherapy.

Jian Gu, Joe Y. Chang, Yuanqing Ye, 2011, Journal of the National Cancer Institute.

Effects of insulin-like growth factor binding protein-3 and farnesyltransferase inhibitor SCH66336 on Akt expression and apoptosis in non-small-cell lung cancer cells.

F. Khuri, R. Lotan, W. Hong, 2004, Journal of the National Cancer Institute.

Loss of Fhit expression is a predictor of poor outcome in tongue cancer.

W. Hong, J. Soria, L. Mao, 2001, Cancer research.

Advances in Brief Benzo [ fl ] pyrene Diol Epoxide-induced 3 p 21 . 3 Aberrations and Genetic Predisposition to Lung Cancer 1

Xifeng, J. Minna, W. Hong, 2006 .

Heterodimerization of insulin-like growth factor receptor/epidermal growth factor receptor and induction of survivin expression counteract the antitumor action of erlotinib.

Edward S. Kim, W. Hong, Ho-Yyoung Lee, 2006, Cancer research.

Cyclin D1 genotype, response to biochemoprevention, and progression rate to upper aerodigestive tract cancer.

Diane D. Liu, W. Hong, J. Lee, 2003, Journal of the National Cancer Institute.

Progress in Chemoprevention Drug Development: The Promise of Molecular Biomarkers for Prevention of Intraepithelial Neoplasia and Cancer—A Plan to Move Forward

G. Mills, S. Lam, M. Spitz, 2006, Clinical Cancer Research.

Deguelin-Induced Inhibition of Cyclooxygenase-2 Expression in Human Bronchial Epithelial Cells

W. Hong, J. Pezzuto, J. Kurie, 2004, Clinical Cancer Research.

Phase II study of tallysomycin S10b in patients with advanced head and neck cancer

W. Hong, M. Rozencweig, I. Krakoff, 1990, Investigational New Drugs.

An attenuated adenovirus, ONYX-015, as mouthwash therapy for premalignant oral dysplasia.

C. Rudin, S. Lippman, W. Hong, 2003, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

An A ttenuated A denovirus, O NYX-015, A s M outhwash T herapy for P remalignant O ral D ysplasia

C. Rudin, S. Lippman, W. Hong, 2006 .

Reduced expression levels of nucleotide excision repair genes in lung cancer: a case-control analysis.

M. Spitz, W. Hong, Q. Wei, 2000, Carcinogenesis.

Cyclooxygenase-2 overexpression is a marker of poor prognosis in stage I non-small cell lung cancer.

S. Lippman, F. Khuri, R. Lotan, 2001, Clinical cancer research : an official journal of the American Association for Cancer Research.

Induction chemotherapy and cetuximab for locally advanced squamous cell carcinoma of the head and neck: results from a phase II prospective trial.

A. Garden, S. Lippman, W. Hong, 2010, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Activation of p53 gene expression in premalignant lesions during head and neck tumorigenesis.

W. Hong, J. Roth, W. Hittelman, 1994, Cancer research.

Expression of DMBT1, a candidate tumor suppressor gene, is frequently lost in lung cancer.

J. Minna, A. Gazdar, W. Hong, 1999, Cancer research.

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J. Minna, W. Hong, A. Gazdar, 1999 .

Methylenetetrahydrofolate reductase polymorphisms and risk of squamous cell carcinoma of the head and neck: A case‐control analysis

Hongbing Shen, M. Spitz, S. Shete, 2005, International journal of cancer.

Polymorphisms of methylene-tetrahydrofolate reductase and risk of lung cancer: a case-control study.

Hongbing Shen, M. Spitz, W. Hong, 2001, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.

Prognostic implication of microsatellite alteration profiles in early-stage non-small cell lung cancer.

F. Khuri, W. Hong, J. Lee, 2000, Clinical cancer research : an official journal of the American Association for Cancer Research.

Survival after treatment of small-cell lung cancer: an endless uphill battle.

W. Hong, B. Glisson, W. Hong, 1997, Journal of the National Cancer Institute.

EGFR tyrosine kinase domain mutations are detected in histologically normal respiratory epithelium in lung cancer patients.

J. Minna, W. Hong, J. Roth, 2005, Cancer research.

Evidence That Retinoic Acid Receptor β Induction by Retinoids Is Important for Tumor Cell Growth Inhibition*

R. Lotan, W. Hong, Shi-Yong Sun, 2000, The Journal of Biological Chemistry.

IMPACT (Imaging and Molecular Markers for Patients with Lung Cancer: Approaches with Molecular Targets and Complementary, Innovative and Therapeutic Modalities)

W. Hong, R. Herbst, W. Hong, 2009 .

Thymidylate Synthase 5′- and 3′-Untranslated Region Polymorphisms Associated with Risk and Progression of Squamous Cell Carcinoma of the Head and Neck

M. Spitz, W. Hong, Q. Wei, 2004, Clinical Cancer Research.

HER Family Receptor Abnormalities in Lung Cancer Brain Metastases and Corresponding Primary Tumors

Carmen Behrens, Ignacio I Wistuba, K. Aldape, 2009, Clinical Cancer Research.

Focus on head and neck cancer.

W. Hong, L. Mao, V. Papadimitrakopoulou, 2004, Cancer cell.

All-trans-retinoic Acid Increases Transforming Growth Factor-β2 and Insulin-like Growth Factor Binding Protein-3 Expression through a Retinoic Acid Receptor-α-dependent Signaling Pathway*

W. Hong, J. Kurie, P. Cohen, 1997, The Journal of Biological Chemistry.

Prediction of Survival in Resected Non–Small Cell Lung Cancer Using a Protein Expression–Based Risk Model: Implications for Personalized Chemoprevention and Therapy

Edward S. Kim, Diane D. Liu, W. Hong, 2013, Clinical Cancer Research.

Retinoic acid receptor- and retinoid X receptor-selective retinoids activate signaling pathways that converge on AP-1 and inhibit squamous differentiation in human bronchial epithelial cells.

R. Lotan, W. Hong, J. Nesbitt, 1996, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.

Implication of the Insulin-like Growth Factor-IR Pathway in the Resistance of Non–small Cell Lung Cancer Cells to Treatment with Gefitinib

Edward S. Kim, W. Hong, F. Ciardiello, 2007, Clinical Cancer Research.

Implication of the Insulin-like Growth Factor-IRPathway in the Resistance of Non ^ small Cell Lung Cancer Cells toTreatment with

Edward S. Kim, W. Hong, F. Ciardiello, 2007 .

The synthetic retinoid CD437 selectively induces apoptosis in human lung cancer cells while sparing normal human lung epithelial cells.

R. Lotan, W. Hong, Shi-Yong Sun, 2002, Cancer research.

Identification of Gene Signatures and Molecular Markers for Human Lung Cancer Prognosis using an In vitro Lung Carcinogenesis System

R. Lotan, W. Hong, I. Wistuba, 2009, Cancer Prevention Research.

Squamous metaplasia of the bronchial mucosa and its relationship to smoking.

S Lippman, S. Lippman, R. Morice, 1993, Chest.

Chemoprevention of lung cancer.

Edward S. Kim, W. Hong, S. Lantuejoul, 2003, The Lancet. Oncology.

Hypermethylation of the Retinoic Acid Receptor-β2 Gene in Head and Neck Carcinogenesis

S. Lippman, R. Lotan, W. Hong, 2004, Clinical Cancer Research.

Mechanisms of apoptosis induced by the synthetic retinoid CD437 in human non-small cell lung carcinoma cells

R. Lotan, W. Hong, Shi-Yong Sun, 1999, Oncogene.

Effects of N-(4-hydroxyphenyl)retinamide on hTERT expression in the bronchial epithelium of cigarette smokers.

W. Hong, R. Morice, C. Moon, 2002, Journal of the National Cancer Institute.

N-(4-hydroxyphenyl)retinamide in the chemoprevention of squamous metaplasia and dysplasia of the bronchial epithelium.

S. Lippman, F. Khuri, R. Lotan, 2000, Clinical cancer research : an official journal of the American Association for Cancer Research.

Dietary folate intake and lung cancer risk in former smokers: a case-control analysis.

Hongbing Shen, M. Spitz, W. Hong, 2003, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.

Comprehensive Biomarker Analysis and Final Efficacy Results of Sorafenib in the BATTLE Trial

Michael Peyton, John D. Minna, Lixia Diao, 2013, Clinical Cancer Research.

Predictive Biomarkers and Personalized Medicine Comprehensive Biomarker Analysis and Final Ef fi cacy Results of Sorafenib in the BATTLE Trial

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Laryngeal preservation for advanced laryngeal and hypopharyngeal cancers.

A. Garden, R. Weber, W. Hong, 1995, Archives of otolaryngology--head & neck surgery.

In vitro BPDE‐induced DNA adducts in peripheral lymphocytes as a risk factor for squamous cell carcinoma of the head and neck

M. Spitz, W. Hong, E. Sturgis, 2001, International journal of cancer.

A prospective randomized trial of methotrexate versus cisplatin in the treatment of recurrent squamous cell carcinoma of the head and neck

S. Shapshay, W. Hong, B. Issell, 1983, Cancer.

Phase II study of paclitaxel, ifosfamide, and carboplatin in patients with recurrent or metastatic head and neck squamous cell carcinoma

S. Lippman, F. Khuri, W. Hong, 2001, Cancer.

Sensitivity to DNA damage induced by benzo(a)pyrene diol epoxide and risk of lung cancer: a case-control analysis.

M. Spitz, W. Hong, Q. Wei, 2001, Cancer research.

The evolution of treatment outcomes for resected stage IIIA non-small cell lung cancer over 16 years at a single institution.

W. Hong, J. Roth, S. Swisher, 2005, The Journal of thoracic and cardiovascular surgery.

Phase II study of induction chemotherapy with paclitaxel, ifosfamide, and carboplatin (TIC) for patients with locally advanced squamous cell carcinoma of the head and neck

A. Garden, S. Lippman, F. Khuri, 2002, Cancer.

An Expanded Risk Prediction Model for Lung Cancer

M. Spitz, W. Hong, Xifeng Wu, 2008, Cancer Prevention Research.

Stress Pathway Activation Induces Phosphorylation of Retinoid X Receptor*

W. Hong, J. Woodgett, D. Mangelsdorf, 2000, The Journal of Biological Chemistry.

Evidence of a retinoid signaling alteration involving the activator protein 1 complex in tumorigenic human bronchial epithelial cells and non-small cell lung cancer cells.

W. Hong, J. Kurie, M. Dawson, 1997, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.

All-trans Retinoic Acid Converts E 2 F into a Transcriptional Suppressor and Inhibits the Growth of Normal Human Bronchial Epithelial Cells Through a Retinoic Acid Receptor – dependent Signaling Pathway

W. Hong, M. Andreeff, J. Kurie, 1998 .

Potential of retinoids in cancer prevention.

S. Lippman, W. Hong, J. Kurie, 1994, Cancer treatment reviews.

Increased Retinoic Acid Responsiveness in Lung Carcinoma Cells that Are Nonresponsive Despite the Presence of Endogenous Retinoic Acid Receptor (RAR) β by Expression of Exogenous Retinoid Receptors Retinoid X Receptor α, RARα, and RARγ

Reuben Lotan, R. Lotan, W. Hong, 2001 .

Proliferative changes in the bronchial epithelium of former smokers treated with retinoids.

Diane D. Liu, J. Minna, F. Khuri, 2007, Journal of the National Cancer Institute.

Overexpression of retinoic acid receptor beta in head and neck squamous cell carcinoma cells increases their sensitivity to retinoid-induced suppression of squamous differentiation by retinoids.

W. Hong, D. Lotan, R. Lotan, 1999, Cancer research.

Implication of c-Myc in apoptosis induced by the retinoid CD437 in human lung carcinoma cells

R. Lotan, W. Hong, Shi-Yong Sun, 1999, Oncogene.

All-trans-Retinoic Acid Inhibits Jun N-terminal Kinase-dependent Signaling Pathways*

W. Hong, J. Kurie, M. Dawson, 1998, The Journal of Biological Chemistry.

Expression of retinoic acid receptor beta is associated with inhibition of keratinization in human head and neck squamous carcinoma cells.

W. Hong, C. Zou, R. Lotan, 1999, Differentiation; research in biological diversity.

Gene Expression Profiling Predicts the Development of Oral Cancer

Li Mao, Edward S. Kim, Pierre Saintigny, 2011, Cancer Prevention Research.

Phase II study of 13-cis-retinoic acid and interferon-alpha 2a in patients with advanced squamous cell lung cancer.

S. Lippman, D. V. Von Hoff, W. Hong, 1993, Anti-cancer drugs.

Expression of hepatoma-derived growth factor is a strong prognostic predictor for patients with early-stage non-small-cell lung cancer.

F. Khuri, W. Hong, J. Lee, 2004, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Identification and validation of metastasis-associated proteins in head and neck cancer cell lines by two-dimensional electrophoresis and mass spectrometry

Li Mao, Wei Hu, Weiguo Wu, 2004, Clinical & Experimental Metastasis.

Biochemopreventive therapy for patients with premalignant lesions of the head and neck and p53 gene expression.

S. Lippman, J. J. Lee, A. Gillenwater, 2000, Journal of the National Cancer Institute.

Sequential increases in proliferating cell nuclear antigen expression in head and neck tumorigenesis: a potential biomarker.

W. Hong, W. Hittelman, D. Shin, 1993, Journal of the National Cancer Institute.

Primary chemotherapy of brain metastasis in small-cell lung cancer.

W. Murphy, B. Glisson, J. Lee, 1989, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Polymorphisms of FAS and FAS Ligand Genes Involved in the Death Pathway and Risk and Progression of Squamous Cell Carcinoma of the Head and Neck

M. Spitz, W. Hong, Q. Wei, 2006, Clinical Cancer Research.

Hypoxia-inducible factor 1alpha and antiangiogenic activity of farnesyltransferase inhibitor SCH66336 in human aerodigestive tract cancer.

Edward S. Kim, W. Hong, Ji-Youn Han, 2005, Journal of the National Cancer Institute.

Randomized phase III trial of low-dose isotretinoin for prevention of second primary tumors in stage I and II head and neck cancer patients.

Edward S. Kim, S. Lippman, F. Khuri, 2006, Journal of the National Cancer Institute.

Randomized trial of 13-cis retinoic acid compared with retinyl palmitate with or without beta-carotene in oral premalignancy.

Edward S. Kim, S. Lippman, F. Khuri, 2009, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

A randomized trial comparing perioperative chemotherapy and surgery with surgery alone in resectable stage IIIA non-small-cell lung cancer.

J. Roth, E. Atkinson, F. Fossella, 1994, Journal of the National Cancer Institute.

Epidermal Growth Factor Receptor Expression in Head and Neck Tumorigenesis and Saturation of EGFR with Monoclonal Antibody RG83852

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Identification of novel antiangiogenic anticancer activities of deguelin targeting hypoxia‐inducible factor‐1 alpha

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Serum Levels of Insulin Growth Factor (IGF-I) and IGF-Binding Protein Predict Risk of Second Primary Tumors in Patients with Head and Neck Cancer

M. Spitz, W. Hong, Xifeng Wu, 2004, Clinical Cancer Research.

Implication of protein kinase B/Akt and Bcl-2/Bcl-XL suppression by the farnesyl transferase inhibitor SCH66336 in apoptosis induction in squamous carcinoma cells.

F. Khuri, R. Lotan, W. Hong, 2003, Cancer research.

Reduced DNA Repair Capacity for Removing Tobacco Carcinogen–Induced DNA Adducts Contributes to Risk of Head and Neck Cancer but not Tumor Characteristics

M. Spitz, R. Weber, S. Lippman, 2010, Clinical Cancer Research.

XPA polymorphism associated with reduced lung cancer risk and a modulating effect on nucleotide excision repair capacity.

M. Spitz, W. Hong, Xifeng Wu, 2003, Carcinogenesis.

Chromosome polysomy and histological characteristics in oral premalignant lesions.

S. Lippman, W. Hong, W. Hittelman, 2001, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.

p 53 Protein Accumulation and Genomic Instability in Head and Neck Multistep Tumorigenesis 1

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The prognostic role of loss of insulin-like growth factor-binding protein-3 expression in head and neck carcinogenesis.

Diane D. Liu, W. Hong, V. Papadimitrakopoulou, 2006, Cancer letters.

Prognostic implications of tumoral expression of insulin like growth factors 1 and 2 in patients with non-small-cell lung cancer.

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Epidermal growth factor receptor and K‐Ras mutations and resistance of lung cancer to insulin‐like growth factor 1 receptor tyrosine kinase inhibitors

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Clinical significance of cyclin B1 protein expression in squamous cell carcinoma of the tongue.

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Oral Premalignant Lesions Chromosome Polysomy and Histological Characteristics in Updated

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Effective treatment of early endobronchial cancer with regional administration of liposome-p53 complexes.

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Increased phospho-AKT (Ser(473)) expression in bronchial dysplasia: implications for lung cancer prevention studies.

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Loss of PTEN expression as a prognostic marker for tongue cancer.

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Inhibition of c-Src expression and activation in malignant pleural mesothelioma tissues leads to apoptosis, cell cycle arrest, and decreased migration and invasion

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The Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor ZD1839 (Iressa) Suppresses c-Src and Pak1 Pathways and Invasiveness of Human Cancer Cells

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New DNA Methylation Markers and Global DNA Hypomethylation Are Associated with Oral Cancer Development

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Oral Epithelium as a Surrogate Tissue for Assessing Smoking-Induced Molecular Alterations in the Lungs

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Podoplanin: a novel marker for oral cancer risk in patients with oral premalignancy.

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Met Receptor Tyrosine Kinase and Chemoprevention of Oral Cancer

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Cancer chemoprevention in the 21st century: genetics, risk modeling, and molecular targets.

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Concordance of oral HPV prevalence between patients with oropharyngeal cancer and their partners

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Suppression of retinoic acid receptor beta in non-small-cell lung cancer in vivo: implications for lung cancer development.

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Phase II clinical trial of didemnin B in previously treated small cell lung cancer

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Vindesine versus Vindesine with Cis-Platinum in Metastatic Non-Small Cell Lung Cancer

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Treatment of patients with small-cell lung cancer refractory to etoposide and cisplatin with the topoisomerase I poison topotecan.

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Resectability of Small‐Cell Lung Cancer Following Induction Chemotherapy in Patients with Limited Disease (Stage II‐IIIb)

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Cisplatin, etoposide, and paclitaxel in the treatment of patients with extensive small-cell lung carcinoma.

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Increased Phospho-AKT (Ser473) Expression in Bronchial Dysplasia

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Cancer Prevention by Delay

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Mutagen sensitivity to benzo(a)pyrene diol epoxide and the risk of squamous cell carcinoma of the head and neck.

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Evaluation of Src Tyr419 as a predictive biomarker in a neoadjuvant trial using dasatinib in resectable malignant pleural mesothelioma.

Jeffrey E. Lee, S. Lippman, I. Wistuba, 2010 .

Dual mechanisms of action of the retinoid CD437: nuclear retinoic acid receptor-mediated suppression of squamous differentiation and receptor-independent induction of apoptosis in UMSCC22B human head and neck squamous cell carcinoma cells.

R. Lotan, W. Hong, R. Lotan, 2000, Molecular pharmacology.

Nuclear factor-kappaB (NF-kappaB) is frequently expressed in lung cancer and preneoplastic lesions.

Diane D. Liu, W. Hong, I. Wistuba, 2006, Cancer.

Membrane Carbonic Anhydrase IX Expression and Relapse Risk in Resected Stage I–II Non–Small-Cell Lung Cancer

Diane D. Liu, W. Hong, J. Roth, 2014, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

Enolase-alpha is frequently down-regulated in non-small cell lung cancer and predicts aggressive biological behavior.

W. Hong, Y. Chang, L. Mao, 2003, Clinical cancer research : an official journal of the American Association for Cancer Research.

Genetic Variants in the PI3K/PTEN/AKT/mTOR Pathway Predict Head and Neck Cancer Patient Second Primary Tumor/Recurrence Risk and Response to Retinoid Chemoprevention

Edward S. Kim, M. Spitz, S. Lippman, 2012, Clinical Cancer Research.

Identification and validation of differences in protein levels in normal, premalignant, and malignant lung cells and tissues using high-throughput Western Array and immunohistochemistry.

R. Lotan, W. Hong, I. Wistuba, 2006, Cancer research.

Retinoids in oncology

R. Lotan, W. Hong, W. Hong, 1993 .

Immunohistochemical Expression of Basic Fibroblast Growth Factor and Fibroblast Growth Factor Receptors 1 and 2 in the Pathogenesis of Lung Cancer

R. Lotan, W. Hong, I. Wistuba, 2008, Clinical Cancer Research.

Induction of p53-regulated genes and tumor regression in lung cancer patients after intratumoral delivery of adenoviral p53 (INGN 201) and radiation therapy.

J. Gu, F. Khuri, W. Hong, 2003, Clinical cancer research : an official journal of the American Association for Cancer Research.

Chemopreventive effects of deguelin, a novel Akt inhibitor, on tobacco-induced lung tumorigenesis.

R. Price, W. Hong, D. Cody, 2005, Journal of the National Cancer Institute.

PROSPECT (Profiling of Resistance Patterns & Oncogenic Signaling Pathways in Evaluation of Cancers of the Thorax and Therapeutic Target Identification)

W. Hong, D. Stewart, W. Hong, 2008 .

Epidermal growth factor receptor, cyclooxygenase-2, and BAX expression in the primary non-small cell lung cancer and brain metastases.

W. Hong, J. Roth, T. McDonnell, 2003, Clinical cancer research : an official journal of the American Association for Cancer Research.

Strategies in Lung Cancer Chemoprevention

Edward S. Kim, F. Khuri, W. Hong, 2005 .

Alterations of PTEN/MMAC1, a candidate tumor suppressor gene, and its homologue, PTH2, in small cell lung cancer cell lines

W. Hong, L. Mao, L. Su, 1998, Oncogene.

Antisense oligonucleotides directed at the bcl-xl gene product augment chemotherapy response in mesothelioma.

W. Hong, Xiaobo X. Cao, Steven D. Miller, 2004, Molecular cancer therapeutics.

Predictors of Survival in Never-Smokers with Non–Small Cell Lung Cancer: A Large-Scale, Two-Phase Genetic Study

M. Spitz, J. Minna, S. Lippman, 2012, Clinical Cancer Research.

Retinoids in Head and Neck Chemoprevention

W. Hong, V. Papadimitrakopoulou, W. Hong, 1997, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

Biomarkers in aerodigestive tract chemoprevention trials

S. Lippman, R. Lotan, W. Hong, 1993 .

Determination of biomarkers for intermediate end points in chemoprevention trials.

S. Lippman, R. Lotan, W. Hong, 1992, Cancer research.

Retinoids in Head and Neck Chemoprevention (44179)

W. Hong, V. Papadimitrakopoulou, W. Hong, 1997 .

The Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor ZD 1839 ( Iressa ) Suppresses cSrc and Pak 1 Pathways and Invasiveness of Human Cancer Cells

C. J. Barnes, R. Lotan, W. Hong, 2004 .

Phase II study of a liposome-entrapped cisplatin analog (L-NDDP) administered intrapleurally and pathologic response rates in patients with malignant pleural mesothelioma.

W. Hong, S. Swisher, R. Perez-soler, 2005, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

C-CAM1, a candidate tumor suppressor gene, is abnormally expressed in primary lung cancers.

W. Hong, L. Mao, S. H. Lin, 2000, Clinical cancer research : an official journal of the American Association for Cancer Research.

Phase II trial of carboplatin plus cisplatin in recurrent and advanced squamous cell carcinoma of the head and neck.

W. Hong, R. Winn, I. Dimery, 1991, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Gender differences in p53 mutational status in small cell lung cancer.

W. Hong, L. Mao, J. Ro, 1999, Cancer research.

Advances in Brief Gender Differences in p 53 Mutational Status in Small Cell Lung Cancer 1

Diane D. Liu, W. Hong, L. Mao, 1999 .

Phase II study of TAS-106 in patients with platinum-failure recurrent or metastatic head and neck cancer and nasopharyngeal cancer

W. Hong, A. Tsao, E. Hui, 2013, Cancer medicine.

Influence of technologic advances on outcomes in patients with unresectable, locally advanced non-small-cell lung cancer receiving concomitant chemoradiotherapy.

Radhe Mohan, Edward S. Kim, Xiong Wei, 2010, International journal of radiation oncology, biology, physics.

Interleukin-11 Receptor Is a Candidate Target for Ligand-Directed Therapy in Lung Cancer: Analysis of Clinical Samples and BMTP-11 Preclinical Activity.

R. Sidman, Menghong Sun, W. Hong, 2016, The American journal of pathology.

O-71 Hyperfractionated and accelerated thoracic radiation therapy (HFXA/TRT) increased survival compared to daily TRT for limited small cell lung cancer (LSCLC) patients treated with concurrent chemotherapy

R. Herbst, C. Stevens, R. Komaki, 2003 .

Personalizing lung cancer prevention through a reverse migration strategy.

Edward S. Kim, W. Hong, I. Wistuba, 2013, Topics in current chemistry.

Intratumoral Genetic Heterogeneity in Primary Head and Neck Squamous Carcinoma Using Microsatellite Markers

W. Hong, J. Batsakis, H. Goepfert, 1997, Diagnostic molecular pathology : the American journal of surgical pathology, part B.

INDUCTION CHEMOTHERAPY OF ADVANCED PREVIOUSLY UNTREATED SQUAMOUS CELL HEAD AND NECK CANCER WITH CISPLATIN AND BLEOMYCIN

S. Shapshay, W. Hong, S. Strong, 1980 .

P h a s e I I a n d B i o logic S tudy o f I nterferon A lfa, R etinoic Acid, a nd C isplatin i n A dvanced S quamous S kin C ancer

Diane D. Liu, S. Lippman, F. Khuri, 2002 .

Cyclin B1 overexpression and resistance to radiotherapy in head and neck squamous cell carcinoma.

Diane D. Liu, K. Ang, W. Hong, 2002, Cancer research.

Changes in keratin expression during 7,12-dimethylbenz[a]anthracene-induced hamster cheek pouch carcinogenesis.

T. Slaga, W. Hong, D. Roop, 1990, Cancer research.

Retinoids and chemoprevention: Clinical and basic studies

S. Lippman, W. Hong, J. Kurie, 1995, Journal of cellular biochemistry. Supplement.

A myeloperoxidase polymorphism associated with reduced risk of lung cancer.

M. Spitz, W. Hong, Xifeng Wu, 2002, Lung cancer.

The incidence of hypercalcemia in squamous cell carcinoma of the head and neck.

W. Hong, E. Dorman, M. Strong, 1984, Head & neck surgery.

Fluorouracil, doxorubicin, cyclophosphamide, and cisplatin combination chemotherapy in advanced or recurrent salivary gland carcinoma.

W. Hong, S. Legha, I. Dimery, 1990, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Response of Non–Small Cell Lung Cancer Cells to the Inhibitors of Phosphatidylinositol 3-Kinase/Akt- and MAPK Kinase 4/c-Jun NH2-Terminal Kinase Pathways: An Effective Therapeutic Strategy for Lung Cancer

W. Hong, Y. Suh, Suyun Huang, 2005, Clinical Cancer Research.

Identification of receptor-selective retinoids that are potent inhibitors of the growth of human head and neck squamous cell carcinoma cells.

R. Lotan, W. Hong, Shi-Yong Sun, 2000, Clinical cancer research : an official journal of the American Association for Cancer Research.

The Synthetic Retinoid CD 437 Selectively Induces Apoptosis in Human Lung Cancer Cells while Sparing Normal Human Lung Epithelial Cells 1

R. Lotan, W. Hong, Shi-Yong Sun, 2002 .

Transcriptomic architecture of the adjacent airway field cancerization in non-small cell lung cancer.

K. Coombes, Jing Wang, W. Hong, 2014, Journal of the National Cancer Institute.

Frequent expression of MAGE1 tumor antigens in bronchial epithelium of smokers without lung cancer.

Diane D. Liu, W. Hong, J. Lee, 2011, Experimental and therapeutic medicine.

The association of microsomal epoxide hydrolase polymorphisms and lung cancer risk in African-Americans and Mexican-Americans.

C I Amos, M. Spitz, W. Hong, 2001, Carcinogenesis.

Associations between cytochrome P4502E1 genotype, mutagen sensitivity, cigarette smoking and susceptibility to lung cancer.

M. Spitz, W. Hong, Xifeng Wu, 1997, Carcinogenesis.

Joint effect of insulin-like growth factors and mutagen sensitivity in lung cancer risk.

M. Spitz, W. Hong, Xifeng Wu, 2000, Journal of the National Cancer Institute.

Phase I trial of cisplatin, pemetrexed, and imatinib mesylate in chemonaive patients with unresectable malignant pleural mesothelioma.

W. Hong, I. Wistuba, J. Lee, 2014, Clinical lung cancer.

Differential expression of E-cadherin and type IV collagenase genes predicts outcome in patients with stage I non-small cell lung carcinoma.

C. Bucana, F. Khuri, W. Hong, 2000, Clinical cancer research : an official journal of the American Association for Cancer Research.

Recent advances in head and neck cancer--larynx preservation and cancer chemoprevention: the Seventeenth Annual Richard and Hinda Rosenthal Foundation Award Lecture.

S. Lippman, W. Hong, G. Wolf, 1993, Cancer research.

Suppression by retinoic acid of epidermal growth factor receptor autophosphorylation and glycosylation in cultured human head and neck squamous carcinoma cells.

R. Lotan, W. Hong, P. Steck, 1992, Journal of the National Cancer Institute. Monographs.

Dose escalation of gemcitabine is possible with concurrent chest three-dimensional rather than two-dimensional radiotherapy: a phase I trial in patients with stage III non-small-cell lung cancer.

W. Hong, R. Herbst, R. Komaki, 2009, International journal of radiation oncology, biology, physics.

Initial clinical trial of oral TAC-101, a novel retinoic acid receptor-alpha selective retinoid, in patients with advanced cancer.

W. Hong, J. Marshall, N. Rizvi, 2002, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Bleomycin Pneumonitis Potentiated by Oxygen Administration

R. J. Cersosimo, M. Bally, J. Feliu, 1985, Drug intelligence & clinical pharmacy.

Retinoic A cid R eceptor-Beta a s a P rognostic I ndicator i n Stage I N on-Small-Cell L ung C ancer

S. Lippman, F. Khuri, R. Lotan, 2000 .

Association of Ki-67, p53, and bcl-2 expression of the primary non-small-cell lung cancer lesion with brain metastatic lesion.

W. Hong, J. Roth, T. McDonnell, 2002, International journal of radiation oncology, biology, physics.

Characterizing the Molecular Spatial and Temporal Field of Injury in Early-Stage Smoker Non–Small Cell Lung Cancer Patients after Definitive Surgery by Expression Profiling

Edward S. Kim, K. Coombes, Jing Wang, 2012, Cancer Prevention Research.

The evolution of mature teratoma from malignant testicular tumors

R. Wittes, W. Hong, W. Whitmore, 1977, Cancer.

Prospective study of the pulmonary toxicity of continuously infused bleomycin.

W. Hong, K. R. Cooper, W. Hong, 1981, Cancer treatment reports.

A Novel Small-Molecule Inhibitor Targeting CREB-CBP Complex Possesses Anti-Cancer Effects along with Cell Cycle Regulation, Autophagy Suppression and Endoplasmic Reticulum Stress

W. Hong, J. Koo, R. Herbst, 2015, PloS one.

Genome-wide association study of genetic predictors of overall survival for non-small cell lung cancer in never smokers.

Joe Y. Chang, V Shane Pankratz, Yuanqing Ye, 2013, Cancer research.

Polymorphisms of FAS and FAS Ligand Genes Involved in the Death Pathway and Risk and Progression of Squamous Cell Carcinoma of the Head and Neck

M. Spitz, C. Amos, E. Sturgis, 2006, Clinical Cancer Research.

Immunohistochemical Expression of Basic Fibroblast Growth Factor and Fibroblast Growth Factor Receptors 1 and 2 in the Pathogenesis of Lung Cancer

R. Lotan, I. Wistuba, C. Behrens, 2008, Clinical Cancer Research.

BATTLE-2 program: A biomarker-integrated targeted therapy study in previously treated patients with advanced non-small cell lung cancer (NSCLC).

K. Coombes, J. Lee, W. Hong, 2013 .

Multiple oral squamous epithelial lesions: are they genetically related?

W. Hong, S. Jang, L. Mao, 2001, Oncogene.

Expression of blood-group antigen A--a favorable prognostic factor in non-small-cell lung cancer.

A. Sahin, B. Brown, W. Hittelman, 1991, The New England journal of medicine.

Phase 2 study of carboplatin, docetaxel, and bevacizumab as frontline treatment for advanced nonsmall‐cell lung cancer

Edward S. Kim, Diane D. Liu, G. Gladish, 2010, Cancer.

Algorithmic guided screening of drug combinations of arbitrary size for activity against cancer cells

P. Damien, G. Mills, S. Lippman, 2009, Molecular Cancer Therapeutics.

Preoperative adjuvant induction chemotherapy in head and neck cancer

S. Shapshay, W. Hong, J. Popkin, 1984 .

Clinical significance of insulin-like growth factor-binding protein-3 expression in stage I non-small cell lung cancer.

Diane D. Liu, F. Khuri, Y. Chang, 2002, Clinical Cancer Research.

Adjuvant chemotherapy of head and neck cancer: the past, the present, and the future.

W. Hong, I. Dimery, A. J. Choksi, 1988, Seminars in oncology.

Continuous cisplatin (24‐hour) and 5‐fluorouracil (120‐hour) infusion in recurrent head and neck squamous cell carcinoma

W. Hong, I. Dimery, R. Byers, 1988, Cancer.

Prospective study of combination chemotherapy with cyclophosphamide, doxorubicin, and cisplatin for unresectable or metastatic malignant pleural mesothelioma

W. Hong, F. Fossella, G. Walsh, 1995, Cancer.

The Synthetic Heteroarotinoid SHetA 2 Induces Apoptosis in Squamous Carcinoma Cells through a Receptor-independent and Mitochondria-dependent Pathway 1

R. Lotan, W. Hong, K. Berlin, 2003 .

Role of paclitaxel, ifosfamide, and cisplatin in patients with recurrent or metastatic squamous cell carcinoma of the head and neck.

S. Lippman, F. Khuri, W. Hong, 1998, Seminars in oncology.

Sorafenib treatment efficacy and KRAS biomarker status in the Biomarker-Integrated Approaches of Targeted Therapy for Lung Cancer Elimination (BATTLE) trial.

W. Hong, I. Wistuba, R. Herbst, 2010 .

Safety and pharmacokinetic effects of TNP-470, an angiogenesis inhibitor, combined with paclitaxel in patients with solid tumors: evidence for activity in non-small-cell lung cancer.

F. Khuri, W. Hong, R. Herbst, 2002, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Phenotypic diversity of the lung vasculature in experimental models of metastases.

W. Hong, Imran T. Mohiuddin, W. Arap, 2005, Chest.

Histopathologic findings after cis-platinum bleomycin therapy in advanced previously untreated head and neck carcinoma.

S. Shapshay, W. Hong, M. Strong, 1978, American journal of surgery.

Evaluation of Difluoromethylornithine for the Chemoprevention of Barrett's Esophagus and Mucosal Dysplasia

W. Hong, R. Broaddus, E. Gerner, 2011, Cancer Prevention Research.

Results of a phase II double-blinded randomized clinical trial of difluoromethylornithine for cervical intraepithelial neoplasia grades 2 to 3.

W. Hong, A. Malpica, M. Follen, 2005, Clinical cancer research : an official journal of the American Association for Cancer Research.

Expression of Interleukin-1 Receptor–Associated Kinase-1 in Non–Small Cell Lung Carcinoma and Preneoplastic Lesions

R. Lotan, W. Hong, I. Wistuba, 2009, Clinical Cancer Research.

From Protocols to Publications: A Study in Selective Reporting of Outcomes in Randomized Trials in Oncology.

D. Berry, L. Ellis, W. Hong, 2015, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Gene therapy for non-small cell lung cancer: a preliminary report of a phase I trial of adenoviral p53 gene replacement.

W. Hong, J. Roth, S. Swisher, 1998, Seminars in oncology.

Superior antiproliferative effects mediated by interferon-alpha entrapped in liposomes against a newly established human lung cancer cell line.

C. Bucana, I. Fidler, D. Shin, 1990, Journal of biological response modifiers.

A Phase II Study of Lonafarnib (SCH66336) in Patients With Chemorefractory, Advanced Squamous Cell Carcinoma of the Head and Neck

Edward S. Kim, F. Khuri, M. Truong, 2009, American journal of clinical oncology.

Estrogen receptors in normal salivary gland and salivary gland carcinoma.

W. Hong, I. Dimery, H. Goepfert, 1987, Archives of otolaryngology--head & neck surgery.

Benzo(a)pyrene diol epoxide-induced chromosomal aberrations and risk of lung cancer.

M. Spitz, M. Bondy, Q. Wei, 1996, Cancer research.

Squamous cell carcinoma of the upper aerodigestive tract. A case comparison analysis

M. Spitz, W. Hong, H. Goepfert, 1988, Cancer.

A novel C/T polymorphism in the core promoter of human de novo cytosine DNA methyltransferase 3B6 is associated with prognosis in head and neck cancer.

Edward S. Kim, W. Hong, L. Mao, 2004, International journal of oncology.

VEGF/VEGFR-2 Upregulates EZH2 Expression in Lung Adenocarcinoma Cells and EZH2 Depletion Enhances the Response to Platinum-Based and VEGFR-2–Targeted Therapy

Milind B. Suraokar, K. Coombes, Jing Wang, 2014, Clinical Cancer Research.

No Association between hOGG1 Ser326Cys polymorphism and risk of squamous cell carcinoma of the head and neck.

M. Spitz, W. Hong, Q. Wei, 2004, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.

Transformation of lymphoma to amyloidoma following radiation therapy.

W. Hong, A. Rubinow, N. Levitan, 1985, Human pathology.

Polyamine measurements in the uterine cervix

R. Lotan, W. Hong, J. Lee, 1997, Journal of cellular biochemistry. Supplement.

Anticlastogenic effects of 13-cis-retinoic acid in vitro.

W. Hong, J. Lee, T. Hsu, 1992, European journal of cancer.

Plasma exchange in six patients with advanced cancers of the head and neck

W. Hong, M. Strong, C. Vaughan, 1985, Journal of clinical apheresis.

THE MANAGEMENT OF SUPERIOR SULCUS TUMORS

W. Hong, J. Roth, C. Stevens, 2001 .

Chemoprevention in head and neck cancer: basic science and clinical application.

W. Hong, V. Papadimitrakopoulou, C. Geyer, 1998, Seminars in radiation oncology.

Differential impacts of insulin-like growth factor-binding protein-3 (IGFBP-3) in epithelial IGF-induced lung cancer development.

W. Hong, I. Wistuba, J. Lee, 2011, Endocrinology.

Joint Effect of Mutagen Sensitivity and Insulin-Like Growth Factors in Predicting the Risk of Developing Secondary Primary Tumors and Tumor Recurrence in Patients with Head and Neck Cancer

M. Spitz, J. Gu, W. Hong, 2006, Clinical Cancer Research.

Epidermal growth factor receptor-targeted therapy with C225 and cisplatin in patients with head and neck cancer.

F. Khuri, W. Hong, D. Shin, 2001, Clinical Cancer Research.

Simultaneous Carcinomas of the Esophagus and Upper Aerodigestive Tract

S. Shapshay, M. Fried, W. Hong, 1980, Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.

Primary chemotherapy of advanced head and neck cancer: where do we go from here?

W. Hong, B. Glisson, W. Hong, 1996, Journal of the National Cancer Institute.

Laryngeal preservation by induction chemotherapy plus radiotherapy in locally advanced head and neck cancer: The M. D. Anderson cancer center experience

A. Garden, R. Weber, S. Lippman, 1994, Head & neck.

Reduced DNA Repair Capacity for Removing Tobacco Carcinogen–Induced DNA Adducts Contributes to Risk of Head and Neck Cancer but not Tumor Characteristics

M. Spitz, R. Weber, S. Lippman, 2010, Clinical Cancer Research.

Polyamine metabolism in carcinoma of the oral cavity compared with adjacent and normal oral mucosa.

W. Hong, D. Ota, K. Nishioka, 1987, American journal of surgery.

Retinoids as antitumor agents: a new age of biological therapy.

W. Hong, J. Kurie, W. Hong, 1999, The cancer journal from Scientific American.

The impact of current staging procedures in assessing disease extent of prostatic adenocarcinoma.

James B. Nickson, W. Hong, R. Finney, 1979, The Journal of urology.

Adjuvant chemotherapy for resectable squamous cell carcinoma of the head and neck. Report on Intergroup Study 0034.

W. Hong, W. Hong, 1992, International journal of radiation oncology, biology, physics.

Clinical Prevention of Recurrence of Colorectal Adenomas by the Combination of Difluoromethylornithine and Sulindac: An Important Milestone

M. Sporn, W. Hong, W. Hong, 2008, Cancer Prevention Research.

Validation of a Novel Statistical Model for Assessing the Synergy of Combined-Agent Cancer Chemoprevention

R. Lotan, W. Hong, J. Lee, 2010, Cancer Prevention Research.

977 Phase I/II trial evaluating blockade of tumour blood supply and tumour cell proliferation with combined bevacizumab and erlotinib HCl as targeted cancer therapy in patients with recurrent non-small cell lung cancer

Edward S. Kim, W. Hong, R. Herbst, 2003 .

Liposomal Encapsulation of Deguelin: Evidence for Enhanced Antitumor Activity in Tobacco Carcinogen–Induced and Oncogenic K-ras–Induced Lung Tumorigenesis

Ho-Yyoung Lee, J. Woo, H. Tran, 2009, Cancer Prevention Research.

Chemoprvention traials in the cervix: Design, feasibility, and recruitment

Kenji Nishioka, W. Hong, R. Richards-Kortum, 1995, Journal of cellular biochemistry. Supplement.

The use of retinoids in head and neck cancer

R. Lotan, W. Hong, S. Schantz, 1987 .

Clinical development plans for cancer chemopreventive agents

G. Omenn, V. Steele, W. Hong, 1996 .

Regression of oral leukoplakia with alpha-tocopherol: a community clinical oncology program chemoprevention study.

S. Lippman, W. Hong, R. Winn, 1993, Journal of the National Cancer Institute.

NCCN Practice Guidelines for Head and Neck Cancers.

R H Wheeler, J. Shah, W. Hong, 2000, Oncology.

Prospective randomized trial of high-dose cisplatin and fluorouracil infusion with or without sodium diethyldithiocarbamate in recurrent and/or metastatic squamous cell carcinoma of the head and neck.

W. Hong, R. Newman, I. Dimery, 1988, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Phase II Randomized, Placebo-Controlled Trial of Green Tea Extract in Patients with High-Risk Oral Premalignant Lesions

Diane D. Liu, I. Wistuba, A. Tsao, 2009, Cancer Prevention Research.

Phase II study of topotecan in patients with non-small cell lung cancer

W. Hong, R. Perez-soler, M. Raber, 1993 .

Phase I studies of gemcitabine

S. Lippman, F. Fossella, J. Abbruzzese, 1993 .

Immunohistochemical overexpression of platelet-derived growth factor receptor-beta (PDGFR-β) is associated with PDGFRB gene copy number gain in sarcomatoid non-small-cell lung cancer.

Milind B. Suraokar, W. Hong, I. Wistuba, 2011, Clinical lung cancer.

Immunohistochemical overexpression of platelet-derived growth factor receptor-beta (PDGFR- β ) is associated with PDGFRB gene copy number gain in sarcomatoid non-small cell lung cancer (NSCLC)

I. Wistuba, A. Tsao, L. Solis, 2013 .

All-trans-retinoic acid increases transforming growth factor-beta2 and insulin-like growth factor binding protein-3 expression through a retinoic acid receptor-alpha-dependent signaling pathway.

W. Hong, J. Kurie, P. Cohen, 1997, The Journal of biological chemistry.

Treatment of previously untreated stage III and IV squamous cell carcinoma of the head and neck.

S. Shapshay, W. Hong, W. Hong, 1980, Otolaryngologic clinics of North America.

Accumulation of p53 Protein and Retinoic Acid Receptorin Retinoid

S. Lippman, R. Lotan, W. Hong, 1997 .

Comparison of p53 immunoreactivity in fresh-cut versus stored slides with and without microwave heating.

J. J. Lee, J. Ro, H. Shin, 1997, Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc.

Phase II trial of 13-cis-retinoic acid plus interferon-α in recurrent head and neck cancer

R. Weber, S. Lippman, W. Hong, 1993, Investigational new drugs.

Phase I/II study of cisplatin, 5-fluorouracil and α-interferon for recurrent carcinoma of the head and neck

S. Lippman, W. Hong, I. Dimery, 2004, Investigational New Drugs.

Rapidly Expanding Retroperitoneal Mass

W. Hong, C. Olsson, S. Gerzof, 1980 .

Induction of TIG3, a putative class II tumor suppressor gene, by retinoic acid in head and neck and lung carcinoma cells and its association with suppression of the transformed phenotype

R. Lotan, W. Hong, R. Chandraratna, 2003, Oncogene.

Phase I trial of alpha-tocopherol effects on 13-cis-retinoic acid toxicity.

S. Lippman, J. Lee, W. Hong, 1997, Annals of Oncology.

Cyclin D1 and Cancer Development in Laryngeal Premalignancy Patients

Diane D. Liu, S. Lippman, W. Hong, 2009, Cancer Prevention Research.

An apple a day...does it really keep the doctor away? The current state of cancer chemoprevention.

Edward S. Kim, W. Hong, W. Hong, 2005, Journal of the National Cancer Institute.

Chemoprevention of Upper Aerodigestive Tract Cancer

Edward S. Kim, F. Khuri, W. Hong, 2005 .

Combination of cis‐platinum and bleomycin prior to surgery and/or radiotherapy compared with radiotherapy alone for the treatment of advanced squamous cell carcinoma of the head and neck

S. Shapshay, W. Hong, C. Vaughan, 1982, Cancer.

Therapeutic Target for Overcoming EGFR Inhibitor Resistance Resistance to EGFR and PI 3 K Inhibitors and Identifies Axl as a Mesenchymal Transition Gene Signature Predicts

Edward S. Kim, J. Weinstein, K. Coombes, 2012 .

Inhibition of N-(4-hydroxyphenyl)retinamide-Induced Apoptosis in Breast Cancer Cells by Galectin-3

R. Lotan, W. Hong, Jin-Hyuk Choi, 2004, Cancer biology & therapy.

Acute Pneumonitis Associated with MOPP Chemotherapy of Hodgkin's Disease

R. J. Cersosimo, W. Hong, S. J. Matthews, 1984, Drug intelligence & clinical pharmacy.

Cis-diamminedichiorplatinum-induced acute renal failure in the rat

W. Hong, B. Trump, J. Kaufman, 1982 .

In vitro protective effects of chemopreventive agents against bleomycin-induced genotoxicity in lymphoblastoid cell lines and peripheral blood lymphocytes of head and neck cancer patients.

M. Spitz, W. Hong, J. Lee, 1993, Cancer detection and prevention.