G. Napolitano

发表

Guidelines for the use and interpretation of assays formonitoring autophagy (3rd edition)

Sangeeta Khare, Xin Qi, Ying Wang, 2016 .

mTOR-dependent phosphorylation controls TFEB nuclear export

Maria Matarese, Andrea Ballabio, Jennifer Lippincott-Schwartz, 2018, Nature Communications.

The CLN3 gene and protein: What we know

D. Kerkovich, A. Vainshtein, Gennaro Napolitano, 2019, Molecular genetics & genomic medicine.

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1

Mark R. Marten, Erinna F. Lee, Dana L. Miller, 2021, Autophagy.

COMMD7 as a novel NEMO interacting protein involved in the termination of NF‐κB signaling

A. Leonardi, M. Incoronato, E. Esposito, 2016, Journal of cellular physiology.

Crystal structure of inhibitor of κB kinase β (IKKβ)

Xuliang Jiang, Hao Wu, Michael Karin, 2011, Nature.

NESCA: A new NEMO/IKKgamma and TRAF6 interacting protein

A. Leonardi, S. Mirra, Gennaro Napolitano, 2009, Journal of cellular physiology.

Vesicular trafficking through cortical actin during exocytosis is regulated by the Rab27a effector JFC1/Slp1 and the RhoA-GTPase–activating protein Gem-interacting protein

W. Kiosses, Gennaro Napolitano, S. Catz, 2012, Molecular biology of the cell.

Polyamines Control eIF5A Hypusination, TFEB Translation, and Autophagy to Reverse B Cell Senescence

A. Ballabio, S. Mohammed, S. Balabanov, 2019, Molecular cell.

Structure of the lysosomal mTORC1–TFEB–Rag–Ragulator megacomplex

J. Hurley, Mariana E. G. de Araujo, Gennaro Napolitano, 2023, Nature.

Non-canonical mTORC1 signaling at the lysosome.

A. Ballabio, Gennaro Napolitano, Chiara Di Malta, 2022, Trends in cell biology.

A substrate-specific mTORC1 pathway underlies Birt-Hogg-Dubé syndrome

A. Ballabio, M. Cesana, L. Huber, 2020, Nature.

TFEB at a glance

A. Ballabio, Gennaro Napolitano, G. Napolitano, 2016, Journal of Cell Science.

Editorial :Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). DOI: 10.1080/15548627.2015.1100356;WOS:000373595400001; 2-s2.0-85013763791&;PMID: 26799652

Lee, Duchen, Izzo, 2016 .

Crystal structure of inhibitor of kappaB kinase beta.

Xuliang Jiang, Hao Wu, Michael Karin, 2011 .

Major histocompatibility class II HLA-DR alpha gene expression in thyrocytes: counter regulation by the class II transactivator and the thyroid Y box protein.

A. Reimold, J. Ting, M. Saji, 1998, Endocrinology.

Cross-regulation of defective endolysosome trafficking and enhanced autophagy through TFEB in UNC13D deficiency

Jinzhong Zhang, Gennaro Napolitano, S. Catz, 2019, Autophagy.

Activation of the transcription factor EB rescues lysosomal abnormalities in cystinotic kidney cells.

A. Ballabio, Jinzhong Zhang, D. Medina, 2016, Kidney international.

Supplementary Information ( SI )

R. Twieg, S. Cherqui, K. Pestonjamasp, 2010 .

Upregulation of the Rab27a-Dependent Trafficking and Secretory Mechanisms Improves Lysosomal Transport, Alleviates Endoplasmic Reticulum Stress, and Reduces Lysosome Overload in Cystinosis

S. Cherqui, Gennaro Napolitano, C. Rocca, 2013, Molecular and Cellular Biology.

Title Impairment of chaperone-mediated autophagy leads to selective lysosomal degradation defects in the lysosomal storage disease cystinosis Permalink

S. Cherqui, K. Pestonjamasp, Gennaro Napolitano, 2015 .

Current methods to analyze lysosome morphology, positioning, motility and function

A. Galione, J. Luzio, C. Futter, 2022, Traffic.

Biallelic mutations in SNX14 cause a syndromic form of cerebellar atrophy and lysosome-autophagosome dysfunction

S. Gabriel, J. Casanova, E. Dikoglu, 2015, Nature Genetics.

TFEB-driven endocytosis coordinates MTORC1 signaling and autophagy

Gregory F Weber, A. Ballabio, D. Medina, 2018, Autophagy.

Munc13-4 interacts with syntaxin 7 and regulates late endosomal maturation, endosomal signaling, and TLR9-initiated cellular responses

Jinzhong Zhang, K. Pestonjamasp, Gennaro Napolitano, 2016, Molecular biology of the cell.

LC3 lipidation is essential for TFEB activation during the lysosomal damage response to kidney injury

A. Ballabio, Y. Okada, Masahiro Yamamoto, 2020, Nature Cell Biology.

TFEBexplorer: An integrated tool to study genes regulated by the stress-responsive Transcription Factor EB

A. Ballabio, D. di Bernardo, Gennaro Napolitano, 2022, Autophagy Reports.

MUNC13-4 Protein Regulates the Oxidative Response and Is Essential for Phagosomal Maturation and Bacterial Killing in Neutrophils*

M. Meijler, Gennaro Napolitano, S. Catz, 2012, The Journal of Biological Chemistry.

Functional Characterization of Wiskott-Aldrich Syndrome Protein and Scar Homolog (WASH), a Bi-modular Nucleation-promoting Factor Able to Interact with Biogenesis of Lysosome-related Organelle Subunit 2 (BLOS2) and γ-Tubulin*

M. D'urso, P. Lappalainen, Gennaro Napolitano, 2010, The Journal of Biological Chemistry.

Crystal structure of inhibitorof k Bkinase b

Y. Lo, M. Karin, Xuliang Jiang, 2011 .

A substrate-specific mTORC1 pathway underlies Birt–Hogg–Dubé syndrome

M. Cesana, G. Bertalot, P. P. Di Fiore, 2020, Nature.

Sphingolipids: The Oil on the TRAFire That Promotes Inflammation

M. Karin, Gennaro Napolitano, G. Napolitano, 2010, Science Signaling.

Phosphorylation of FAM134C by CK2 controls starvation-induced ER-phagy

F. Sacco, A. Efeyan, L. Pinna, 2022, Science advances.

c-Abl Inhibition Activates TFEB and Promotes Cellular Clearance in a Lysosomal Disorder

A. Ballabio, D. Medina, F. Platt, 2020, iScience.

The atypical small GTPase GEM/Kir is a negative regulator of the NADPH oxidase and NETs production through macroautophagy

Jinzhong Zhang, M. Perego, C. Hedrick, 2021, Journal of leukocyte biology.

Cystinosin, the small GTPase Rab11, and the Rab7 effector RILP regulate intracellular trafficking of the chaperone-mediated autophagy receptor LAMP2A

Jinzhong Zhang, A. Cuervo, C. Bucci, 2017, The Journal of Biological Chemistry.

Title Cystinosin , the small GTPase Rab 11 , and the Rab 7 effector RILP regulate intracellular trafficking of the chaperone-mediated autophagy receptor LAMP 2 A Permalink

Jinzhong Zhang, A. Cuervo, C. Bucci, 2017 .

Impairment of chaperone-mediated autophagy leads to selective lysosomal degradation defects in the lysosomal storage disease cystinosis

S. Cherqui, K. Pestonjamasp, C. Rocca, 2015, EMBO molecular medicine.

TFEB and TFE3 control glucose homeostasis by regulating insulin gene expression

M. Cesana, M. Mutarelli, Nunzia Pastore, 2023, The EMBO journal.

Structural basis for mTORC1-dependent regulation of the lysosomal and autophagic transcription factor TFEB

A. Ballabio, J. Hurley, Mariana E. G. de Araujo, 2022, bioRxiv.

Repurposing of tamoxifen ameliorates CLN3 and CLN7 disease phenotype

A. Ballabio, C. Grimm, L. Johannes, 2021, EMBO molecular medicine.

NESCA: A new NEMO/IKKgamma and TRAF6 interacting protein

A. Leonardi, S. Mirra, M. Ursini, 2009, Journal of cellular physiology.

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Alessio Vagnoni, Lucia Barazzuol, Flavia Giamogante, 2024, Nature communications.

A SPLICS reporter reveals α -synuclein regulation of lysosome-mitochondria contacts which affects TFEB nuclear translocation

Alessio Vagnoni, Lucia Barazzuol, Flavia Giamogante, 2022 .