C. Mackenzie

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Antibody Binding to the O-Specific Antigen of Pseudomonas aeruginosa O6 Inhibits Cell Growth

Kevin A. Henry, C. MacKenzie, J. Hall, 2020, Antimicrobial Agents and Chemotherapy.

Biparatopic single-domain antibodies against Axl achieve ultra-high affinity through intramolecular engagement.

M. Jaramillo, Kevin A. Henry, C. MacKenzie, 2021, Biochemical and biophysical research communications.

Selection, characterization, and CDR shuffling of naive llama single-domain antibodies selected against auxin and their cross-reactivity with auxinic herbicides from four chemical families.

Claudia Sheedy, C. MacKenzie, K. Yau, 2006, Journal of agricultural and food chemistry.

Single-Domain Antibodies: Biology, Engineering and Emerging Applications

Kevin A. Henry, C. MacKenzie, C. Mackenzie, 2020 .

Exploration of specificity in germline monoclonal antibody recognition of a range of natural and synthetic epitopes.

C. MacKenzie, C. Brooks, H. Brade, 2008, Journal of molecular biology.

Characterization of polysaccharide conformational epitopes by surface plasmon resonance.

C. MacKenzie, H. Jennings, C. Mackenzie, 2003, Methods in enzymology.

Quantitative analyses of binding affinity and specificity for glycolipid receptors by surface plasmon resonance.

C R MacKenzie, C. MacKenzie, T. Hirama, 2000, Methods in enzymology.

Analysis by Surface Plasmon Resonance of the Influence of Valence on the Ligand Binding Affinity and Kinetics of an Anti-carbohydrate Antibody (*)

C. MacKenzie, S. Narang, D. Bundle, 1996, The Journal of Biological Chemistry.

Llama peripheral B-cell populations producing conventional and heavy chain-only IgG subtypes are phenotypically indistinguishable but immunogenetically distinct

S. Muyldermans, Kevin A. Henry, C. MacKenzie, 2019, Immunogenetics.

Isolation of TGF-β-neutralizing single-domain antibodies of predetermined epitope specificity using next-generation DNA sequencing.

C. Collins, Kevin A. Henry, C. MacKenzie, 2016, Protein engineering, design & selection : PEDS.

A Rational Engineering Strategy for Designing Protein A-Binding Camelid Single-Domain Antibodies

E. Purisima, T. Sulea, Kevin A. Henry, 2016, PloS one.

Isolation of Camelid Single-Domain Antibodies Against Native Proteins Using Recombinant Multivalent Peptide Ligands.

Kevin A. Henry, M. Arbabi-Ghahroudi, C. Mackenzie, 2015, Methods in molecular biology.

α-4-O-methyl-d-glucuronidase component of xylanolytic complexes☆

J. D. Fontana, C. MacKenzie, H. Schneider, 1988 .

Reversibility and competition in the adsorption of Trichoderma reesei cellulase components

C. MacKenzie, R. Neufeld, A. Kyriacou, 1989, Biotechnology and bioengineering.

Cooperativity of Esterases and Xylanases in the Enzymatic Degradation of Acetyl Xylan

C. MacKenzie, P. Biely, H. Schneider, 1986, Bio/Technology.

Flagellin and Outer Surface Proteins from Borrelia burgdorferi Are Not Glycosylated

C. MacKenzie, J. Kelly, N. Rudenko, 2008, Journal of bacteriology.

The intrinsic cysteine and histidine residues of the anti-Salmonella antibody Se155-4: a model for the introduction of new functions into antibody-binding sites.

C. MacKenzie, A. Cunningham, D. Watson, 2014, Protein engineering, design & selection : PEDS.

Antibody recognition of a unique tumor-specific glycopeptide antigen

Lai-Xi Wang, C. MacKenzie, P. Kufer, 2010, Proceedings of the National Academy of Sciences.

Isolation and affinity maturation of hapten-specific antibodies.

C. MacKenzie, J. Hall, C. Sheedy, 2007, Biotechnology advances.

Structure of an Anti-blood Group A Fv and Improvement of Its Binding Affinity without Loss of Specificity*

C. MacKenzie, N. Young, Tomoko Hirama, 2002, The Journal of Biological Chemistry.

The role of CDR H3 in antibody recognition of a synthetic analog of a lipopolysaccharide antigen.

C. MacKenzie, C. Brooks, H. Brade, 2010, Glycobiology.

Antibodies raised against chlamydial lipopolysaccharide antigens reveal convergence in germline gene usage and differential epitope recognition.

C. MacKenzie, C. Brooks, H. Brade, 2010, Biochemistry.

Probing the combining site of an anti-carbohydrate antibody by saturation-mutagenesis: role of the heavy-chain CDR3 residues.

C. MacKenzie, D. Brummell, J. Sadowska, 1993, Biochemistry.

A Mutational Analysis of the Globotriaosylceramide-binding Sites of Verotoxin VT1*

C. MacKenzie, P. Kitov, D. Bundle, 2002, The Journal of Biological Chemistry.

Germline antibody recognition of distinct carbohydrate epitopes

C. MacKenzie, H. Brade, L. Brade, 2003, Nature Structural Biology.

Studies on Cellulose Hydrolysis by Acetivibrio cellulolyticus

C. MacKenzie, G. Patel, G. B. Patel, 1985, Applied and environmental microbiology.

Selection and expression of recombinant single domain antibodies from a hyper-immunized library against the hapten azoxystrobin.

C. MacKenzie, J. Hall, M. Arbabi-Ghahroudi, 2011, Journal of immunological methods.

High affinity anti-Internalin B VHH antibody fragments isolated from naturally and artificially immunized repertoires.

C. MacKenzie, J. Kumaran, H. van Faassen, 2015, Journal of immunological methods.

Thermal stabilization of a single‐chain Fv antibody fragment by introduction of a disulphide bond

J. Baenziger, C. MacKenzie, R. Oomen, 1995, FEBS letters.

Pentamerization of single-domain antibodies from phage libraries: a novel strategy for the rapid generation of high-avidity antibody reagents.

Jamshid Tanha, Emily Stone, J. Brisson, 2004, Journal of molecular biology.

Basis for selection of improved carbohydrate-binding single-chain antibodies from synthetic gene libraries.

C. MacKenzie, R. Brousseau, S. Narang, 1995, Proceedings of the National Academy of Sciences of the United States of America.

Structure of a single-chain antibody variable domain (Fv) fragment complexed with a carbohydrate antigen at 1.7-A resolution.

Y. Li, C. MacKenzie, M. Cygler, 1994, Proceedings of the National Academy of Sciences of the United States of America.

Camelid single-domain antibodies raised by DNA immunization are potent inhibitors of EGFR signaling.

Kevin A. Henry, C. MacKenzie, J. Tanha, 2019, The Biochemical journal.

Identification of three distinct Clostridium thermocellum xylanase genes by molecular cloning

C. MacKenzie, G. Patel, S. Narang, 2004, Archives of Microbiology.

Cloning and nucleotide sequence analysis of the genes determining verocytotoxin production in a porcine edema disease isolate of Escherichia coli.

C. MacKenzie, C. Gyles, J. Brunton, 1988, Microbial pathogenesis.

Microbial degradation of hemicellulosic materials

J. D. Fontana, C. MacKenzie, H. Schneider, 1989 .

Identification of polypeptides with selective affinity to intact mouse cerebellar granule neurons from a random peptide-presenting phage library

Erica Anderson, S. Hou, M. Dove, 2004, Journal of Neuroscience Methods.

Detection of cellulase and xylanase activity in isoelectric-focused gels using agar substrate gels supported on plastic film

C. MacKenzie, R. Williams, C. Mackenzie, 1984 .

Antigen recognition by single-domain antibodies: structural latitudes and constraints

Kevin A. Henry, C. MacKenzie, C. Mackenzie, 2018, mAbs.

Role of the non‐hypervariable FR3 D‐E loop in single‐domain antibody recognition of haptens and carbohydrates

T. Sulea, Kevin A. Henry, C. MacKenzie, 2019, Journal of molecular recognition : JMR.

Cloning, expression, and characterization of a single-domain antibody fragment with affinity for 15-acetyl-deoxynivalenol.

Michael D. McLean, C. MacKenzie, M. Savard, 2008, Molecular immunology.

Effect of Cλ–Cκ Domain Switching on Fab Activity and Yield in Escherichia Coli: Synthesis and Expression of Genes Encoding Two Anti–Carbohydrate Fabs

C. MacKenzie, S. Narang, D. Brummell, 1994, Bio/Technology.

Llama peripheral B-cell populations producing conventional and heavy chain-only IgG subtypes are phenotypically indistinguishable but immunogenetically distinct

S. Muyldermans, Kevin A. Henry, D. Harcus, 2019, Immunogenetics.

Neutralization of Clostridium difficile toxin B with VHH-Fc fusions targeting the delivery and CROPs domains

C. MacKenzie, J. Tanha, Shannon Ryan, 2018, PloS one.

Isolation, characterization and pentamerization of alpha-cobrotoxin specific single-domain antibodies from a naïve phage display library: preliminary findings for antivenom development.

J. Hall, C. S. Stewart, C. Mackenzie, 2007, Toxicon : official journal of the International Society on Toxinology.

A novel pentamer versus pentamer approach to generating neutralizers of verotoxin 1.

C. MacKenzie, Wangxue Chen, Emily Stone, 2007, Molecular immunology.

Production, crystallization and diffraction to atomic resolution of an antibody Fv specific for the blood-group A oligosaccharide antigen.

C. MacKenzie, N. Young, S. V. Evans, 1998, Acta crystallographica. Section D, Biological crystallography.

Nucleotide sequence of a Bacillus circulans xylanase gene.

C. MacKenzie, R. Yang, S. Narang, 1988, Nucleic acids research.

Optimal Design Features of Camelized Human Single-domain Antibody Libraries*

C. MacKenzie, J. Tanha, S. Narang, 2001, The Journal of Biological Chemistry.

Editorial: Single-Domain Antibodies—Biology, Engineering and Emerging Applications

Kevin A. Henry, C. Mackenzie, 2018, Front. Immunol..

Stability-Diversity Tradeoffs Impose Fundamental Constraints on Selection of Synthetic Human VH/VL Single-Domain Antibodies from In Vitro Display Libraries

Kevin A. Henry, C. MacKenzie, J. Tanha, 2017, Front. Immunol..

A Novel Affinity Tag, ABTAG, and Its Application to the Affinity Screening of Single-Domain Antibodies Selected by Phage Display

Kevin A. Henry, C. MacKenzie, J. Baardsnes, 2017, Front. Immunol..

ES1, a new lung carcinoma antibody— an immunohistochemical study

C. MacKenzie, K. Mai, D. G. Perkins, 2006, Histopathology.

Llama DNA Immunization and Isolation of Functional Single-Domain Antibody Binders.

C. MacKenzie, T. Maqbool, M. Rossotti, 2022, Methods in molecular biology.

Identification of a Cross-reactive Epitope Widely Present in Lipopolysaccharide from Enterobacteria and Recognized by the Cross-protective Monoclonal Antibody WN1 222-5*

C. MacKenzie, F. D. Di Padova, H. Brade, 2003, Journal of Biological Chemistry.

The Role of Homophilic Binding in Anti-tumor Antibody R24 Recognition of Molecular Surfaces

A. Houghton, C. MacKenzie, P. Chapman, 1999, The Journal of Biological Chemistry.

Analysis of Receptor Binding by the Channel-forming Toxin Aerolysin Using Surface Plasmon Resonance*

J. T. Buckley, C. MacKenzie, T. Hirama, 1999, The Journal of Biological Chemistry.

Metabolism of Acetivibrio cellulolyticus during optimized growth on glucose, cellobiose and cellulose

C. MacKenzie, G. Patel, G. B. Patel, 1982, European journal of applied microbiology and biotechnology.

Cellodextrin utilization and β-glucosidase production by Bacteroides polypragmatus

C. MacKenzie, G. B. Patel, C. Mackenzie, 1986, Archives of Microbiology.

Antibiotic resistance in Neisseria denitrificans

C. MacKenzie, I. J. Mcdonald, K. Johnson, 1980, Antimicrobial Agents and Chemotherapy.

Molecular basis for the lack of mimicry of Brucella polysaccharide antigens by Ab2gamma antibodies.

C. MacKenzie, D. Watson, D. Bundle, 1999, Molecular immunology.

Application of single-domain antibodies in tumor histochemistry.

C. Mackenzie, Kien T Maik, 2012, Methods in molecular biology.

Detection and characterization of the specific and nonspecific endoglucanases of Trichoderma reesei: Evidence demonstrating endoglucanase activity by cellobiohydrolase II

C. MacKenzie, R. Neufeld, A. Kyriacou, 1987 .

Serum albumin‐binding VHHs with variable pH sensitivities enable tailored half‐life extension of biologics

T. Sulea, Kevin A. Henry, C. MacKenzie, 2020, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Intracellular Expression of a Single Domain Antibody Reduces Cytotoxicity of 15-Acetyldeoxynivalenol in Yeast*

C. MacKenzie, M. Savard, J. Hall, 2009, The Journal of Biological Chemistry.

The assembly of single domain antibodies into bispecific decavalent molecules.

Shenghua Li, Jamshid Tanha, Emily Stone, 2007, Journal of immunological methods.

Glycogen metabolism in the genus Neisseria: synthesis from sucrose by amylosucrase.

K. Johnson, C. Mackenzie, I. Mcdonald, 1978, Canadian journal of microbiology.

Glycogen synthesis by amylosucrase from Neisseria perflava.

C. MacKenzie, I. J. Mcdonald, K. Johnson, 1977, Canadian journal of microbiology.

Enzymic hydrolysis of water-soluble lignin-carbohydrate complexes from Populus deltoides: Effects of combinations of β-mannanases, xylanase, and acetyl xylan esterase

C. MacKenzie, H. Schneider, N. W. Ross, 1992 .

Structure of the D-glucans produced by Neisseria perflava.

M. Perry, K. Johnson, C. Mackenzie, 1978, Canadian journal of microbiology.