Jianxin Dai

发表

Development and Validation of a Peptide Mapping Method for the Characterization of Adalimumab with QDa Detector

Ya-jun Guo, J. Dai, Hao Wang, 2016, Chromatographia.

Elimination of tumor by CD47/PD-L1 dual-targeting fusion protein that engages innate and adaptive immune responses

Ya-jun Guo, J. Dai, Hao Wang, 2018, mAbs.

Cancer immunotherapy using in vitro genetically modified targeted dendritic cells.

Hao Wang, Jian Zhao, Ya-jun Guo, 2008, Cancer research.

Feedback activation of STAT3 mediates trastuzumab resistance via upregulation of MUC1 and MUC4 expression

Ya-jun Guo, Wei Li, J. Dai, 2014, Oncotarget.

TIP30 inhibits growth of HCC cell lines and inhibits HCC xenografts in mice in combination with 5‐FU

Jian Zhao, Ya-jun Guo, Hao Xu, 2006, Hepatology.

Thirty‐kilodalton Tat‐interacting protein suppresses tumor metastasis by inhibition of osteopontin transcription in human hepatocellular carcinoma

W. Cong, Xin Tong, Jian Zhao, 2008, Hepatology.

Combating non-Hodgkin lymphoma by targeting both CD20 and HLA-DR through CD20–243 CrossMab

Xin Tong, Jian Zhao, Ya-jun Guo, 2014, mAbs.

Chemotherapy for gastric cancer by finely tailoring anti-Her2 anchored dual targeting immunomicelles.

Ya-jun Guo, Li Zhang, Wei Li, 2012, Biomaterials.

The fine-tuning of thermosensitive and degradable polymer micelles for enhancing intracellular uptake and drug release in tumors.

Ya-jun Guo, Wei Li, Jinfeng Li, 2011, Biomaterials.

Increased expression of iASPP, regulated by hepatitis B virus X protein-mediated NF-κB activation, in hepatocellular carcinoma.

Xin Tong, Jian Zhao, Ya-jun Guo, 2010, Gastroenterology.

Clearance of Propionibacterium acnes by kupffer cells is regulated by osteopontin through modulating the expression of p47phox.

Ya-jun Guo, J. Dai, Wei-zhu Qian, 2011, Molecular immunology.

A bispecific antibody effectively neutralizes all four serotypes of dengue virus by simultaneous blocking virus attachment and fusion

Ya-jun Guo, Huajing Wang, J. Dai, 2016, mAbs.

Blockade of LIGHT/HVEM and B7/CD28 Signaling Facilitates Long-Term Islet Graft Survival With Development of Allospecific Tolerance

Hao Wang, Ya-jun Guo, J. Dai, 2007, Transplantation.

Treatment of collagen-induced arthritis with an anti-osteopontin monoclonal antibody through promotion of apoptosis of both murine and human activated T cells.

Hao Wang, C. Yang, Huji Xu, 2008, Arthritis and rheumatism.

Transfection of Smac sensitizes tumor cells to etoposide-induced apoptosis and eradicates established human hepatoma in vivo

Jian Zhao, Meng-chao Wu, Ya-jun Guo, 2006, Cancer Gene Therapy.

Generation and characterization of a target-selectively activated antibody against epidermal growth factor receptor with enhanced anti-tumor potency

Hao Wang, Xin Tong, Yun Yang, 2015, mAbs.

Down-regulation of osteopontin suppresses growth and metastasis of hepatocellular carcinoma via induction of apoptosis.

Xin Tong, Jian Zhao, Ya-jun Guo, 2008, Gastroenterology.

Osteopontin induces angiogenesis through activation of PI3K/AKT and ERK1/2 in endothelial cells

D. Zhang, Huajing Wang, J. Dai, 2009, Oncogene.

Preclinical studies of a Pro-antibody-drug conjugate designed to selectively target EGFR-overexpressing tumors with improved therapeutic efficacy

X. Chen, Yun Yang, Ya-jun Guo, 2016, mAbs.

Rod-, flower-, and dumbbell-like MnO2: Highly active catalysts for the combustion of toluene

F. Wang, C. Au, H. Dai, 2012 .

Anti-osteopontin monoclonal antibody prevents ovariectomy-induced osteoporosis in mice by promotion of osteoclast apoptosis.

Jian Zhao, Ya-jun Guo, J. Dai, 2014, Biochemical and biophysical research communications.

Combination of dextran sulfate and recombinant trypsin on aggregation of Chinese hamster ovary cells

Ya-jun Guo, Kai Ma, Geng Kou, 2016, Cytotechnology.

Construction and characterization of a humanized anti‐human CD3 monoclonal antibody 12F6 with effective immunoregulation functions

Ya-jun Guo, J. Dai, Wei-zhu Qian, 2005, Immunology.

Structural Basis for Treating Tumor Necrosis Factor α (TNFα)-associated Diseases with the Therapeutic Antibody Infliximab*

Z. Rao, Ya-jun Guo, Shi Hu, 2013, The Journal of Biological Chemistry.

Functional and stable expression of recombinant human FOXP3 in bacterial cells and development of antigen-specific monoclonal antibodies.

Hao Wang, Ya-jun Guo, Huajing Wang, 2007, Journal of biochemistry.

A humanized anti-osteopontin antibody inhibits breast cancer growth and metastasis in vivo

Hao Wang, Jian Zhao, Ya-jun Guo, 2010, Cancer Immunology, Immunotherapy.

Potent Neutralization of Botulinum Neurotoxin/B by Synergistic Action of Antibodies Recognizing Protein and Ganglioside Receptor Binding Domain

Ya-jun Guo, Huajing Wang, J. Dai, 2012, PloS one.

Acid-induced aggregation propensity of nivolumab is dependent on the Fc

Ya-jun Guo, J. Dai, Hao Wang, 2016, mAbs.

Self-assembled supramolecular nano vesicles for safe and highly efficient gene delivery to solid tumors

Ya-jun Guo, Li Zhang, Wei Li, 2012, International journal of nanomedicine.

Characterization of alanine to valine sequence variants in the Fc region of nivolumab biosimilar produced in Chinese hamster ovary cells

Ya-jun Guo, J. Dai, Hao Wang, 2016, mAbs.

Lysosome-dependent necrosis specifically evoked in cancer cells by gold nanorods.

Li Zhang, Bingdi Chen, Wei Li, 2017, Nanomedicine.

Expression, purification, and characterization of an immunotoxin containing a humanized anti-CD25 single-chain fragment variable antibody fused to a modified truncated Pseudomonas exotoxin A.

Jian Zhao, Ya-jun Guo, Huajing Wang, 2008, Protein expression and purification.

Structural Insights into the Neutralization Mechanism of Monoclonal Antibody 6C2 against Ricin*

Ya-jun Guo, Huajing Wang, J. Dai, 2013, The Journal of Biological Chemistry.

Inhibition of hepatocellular carcinoma growth using immunoliposomes for co-delivery of adriamycin and ribonucleotide reductase M2 siRNA.

Xin Tong, Ya-jun Guo, Wei Li, 2013, Biomaterials.

Novel dual-control poly(N-isopropylacrylamide-co-chlorophyllin) nanogels for improving drug release.

Ya-jun Guo, Li Zhang, Wei Li, 2012, Nanomedicine.

The Mechanism of Apoptosis Regulation by IAP Antagonist Smac/DIABLO

Jian Zhao, Ya-jun Guo, J. Dai, 2003 .

Structural basis for the neutralization and specificity of Staphylococcal enterotoxin B against its MHC Class II binding site

Yuna Sun, Ya-jun Guo, Shi Hu, 2014, mAbs.

A functional motif QLYxxYP is essential for osteopontin induced T lymphocyte activation and migration.

Ya-jun Guo, Huajing Wang, Jie Gao, 2009, Biochemical and biophysical research communications.

A novel functional motif of osteopontin for human lymphocyte migration and survival.

Hao Wang, Jian Zhao, Ya-jun Guo, 2008, Molecular immunology.

Fast Characterization of Fc-Containing Proteins by Middle-Down Mass Spectrometry Following IdeS Digestion

Ya-jun Guo, J. Dai, Hao Wang, 2016, Chromatographia.

In-Depth Characterization of a Pro-Antibody-Drug Conjugate by LC-MS.

Yun Yang, Ya-jun Guo, J. Dai, 2016, Molecular pharmaceutics.

PMMA-templating preparation and catalytic activities of three-dimensional macroporous strontium ferrites with high surface areas for toluene combustion

F. Wang, Lei Zhang, H. Dai, 2013 .

Eradication of non-Hodgkin lymphoma through the induction of tumor-specific T-cell immunity by CD20-Flex BiFP.

Hao Wang, Jian Zhao, Ya-jun Guo, 2013, Blood.

Development and Validation of LC–MS/MS Method for the Quantitation of Infliximab in Human Serum

X. Chen, Ya-jun Guo, J. Dai, 2015, Chromatographia.

TIP30/CC3 expression in breast carcinoma: relation to metastasis, clinicopathologic parameters, and P53 expression.

Jian Zhao, Ya-jun Guo, J. Dai, 2007, Human pathology.

Suppression of Rituximab-resistant B-cell lymphoma with a novel multi-component anti-CD20 mAb nanocluster

Li Zhang, Wei Li, Huafei Li, 2015, Oncotarget.

Fine epitope mapping of humanized anti-IgE monoclonal antibody omalizumab.

Ya-jun Guo, Jie Gao, Wei-zhu Qian, 2008, Biochemical and biophysical research communications.

Polymer-lipid hybrid nanoparticles conjugated with anti-EGF receptor antibody for targeted drug delivery to hepatocellular carcinoma.

Ya-jun Guo, Wei Li, Yunlei Xia, 2014, Nanomedicine.

Development of novel tetravalent anti-CD20 antibodies with potent antitumor activity.

Jian Zhao, Ya-jun Guo, J. Dai, 2008, Cancer research.

PE38KDEL-loaded anti-HER2 nanoparticles inhibit breast tumor progression with reduced toxicity and immunogenicity

Hao Wang, Jian Zhao, Ya-jun Guo, 2009, Breast Cancer Research and Treatment.

Treatment of hepatocellular carcinoma in mice with PE38KDEL type I mutant-loaded poly(lactic-co-glycolic acid) nanoparticles conjugated with humanized SM5-1 F(ab′) fragments

Weizhu Qian, Bohua Li, Yajun Guo, 2008, Molecular Cancer Therapeutics.