I. Engels

发表

The Cancer Cell Line Encyclopedia enables predictive modeling of anticancer drug sensitivity

Adam A. Margolin, Michael P. Morrissey, S. Gabriel, 2012, Nature.

Synthetic lethal targeting of MYC by activation of the DR5 death receptor pathway.

Marc Nasoff, I. H. Engels, Q. Deveraux, 2004, Cancer cell.

Identification of Small Molecule and Genetic Modulators of AON-Induced Dystrophin Exon Skipping by High-Throughput Screening

Paul W Anderson, Yingyao Zhou, Buu P. Tu, 2009, PloS one.

Caspase-8/FLICE functions as an executioner caspase in anticancer drug-induced apoptosis

Claus Belka, Kirsten Lauber, Michael Gregor, 2000, Oncogene.

Caspase-10 Sensitizes Breast Carcinoma Cells to TRAIL-Induced but Not Tumor Necrosis Factor-Induced Apoptosis in a Caspase- 3-Dependent Manner

I. H. Engels, K. Schulze-Osthoff, U. Fischer, 2005, Molecular and Cellular Biology.

Staurosporine and conventional anticancer drugs induce overlapping, yet distinct pathways of apoptosis and caspase activation

I. H. Engels, O. Janssen, K. Schulze-Osthoff, 2001, Oncogene.

Chemical activation of the mechanotransduction channel Piezo1

H. M. Petrassi, I. H. Engels, A. Patapoutian, 2015, eLife.

HTS-Compatible Patient-Derived Cell-Based Assay to Identify Small Molecule Modulators of Aberrant Splicing in Myotonic Dystrophy Type 1

J. Caldwell, I. H. Engels, A. Brinker, 2010, Current chemical genomics.

Expression of calcium-binding proteins MRP8 and MRP14 in inflammatory muscle diseases.

I. H. Engels, T. Vogl, J. Roth, 2003, The American journal of pathology.

Transcription factor AP-2α triggers apoptosis in cardiac myocytes

H. Scheld, I. H. Engels, K. Schulze-Osthoff, 2004, Cell Death and Differentiation.

Mistletoe lectin activates caspase-8/FLICE independently of death receptor signaling and enhances anticancer drug-induced apoptosis.

I. H. Engels, K. Schulze-Osthoff, S. Wesselborg, 1999, Cancer research.

Drug-induced Apoptosis Death Receptor Signaling and Enhances Anticancer Mistletoe Lectin Activates Caspase-8 / FLICE Independently of Updated

I. H. Engels, K. Schulze-Osthoff, S. Wesselborg, 2000 .

Human mature red blood cells express caspase-3 and caspase-8, but are devoid of mitochondrial regulators of apoptosis

I. H. Engels, K. Schulze-Osthoff, K. Lauber, 2001, Cell Death and Differentiation.

Anticancer drugs induce caspase-8/FLICE activation and apoptosis in the absence of CD95 receptor/ligand interaction.

I. H. Engels, K. Schulze-Osthoff, S. Wesselborg, 1999, Blood.

Caspase-2 Can Function Upstream of Bid Cleavage in the TRAIL Apoptosis Pathway*

I. H. Engels, Q. Deveraux, K. Wagner, 2004, Journal of Biological Chemistry.

Addendum: The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

Adam A. Margolin, Michael P. Morrissey, S. Gabriel, 2012, Nature.

A time-resolved fluorescence resonance energy transfer-based assay for DEN1 peptidase activity.

Truc Huynh, J. Caldwell, I. H. Engels, 2009, Analytical biochemistry.

Tips A time-resolved fluorescence resonance energy transfer-based assay for DEN 1 peptidase activity

J. Caldwell, I. H. Engels, A. Brinker, 2009 .

Agonists of proteinase-activated receptor-2 stimulate upregulation of intercellular cell adhesion molecule-1 in primary human keratinocytes via activation of NF-kappa B.

I. H. Engels, C. Stroh, K. Schulze-Osthoff, 2005, The Journal of investigative dermatology.

Identification of inhibitors for putative malaria drug targets among novel antimalarial compounds.

Yu Wang, Gregory J. Crowther, Philip P. Rodenbough, 2011, Molecular and biochemical parasitology.

Caspases: more than just killers?

I. H. Engels, C. Stroh, K. Schulze-Osthoff, 2001, Trends in immunology.

A biochemical screen for GroEL/GroES inhibitors.

Steven M. Johnson, P. Schultz, I. H. Engels, 2014, Bioorganic & medicinal chemistry letters.

Staphylococcus aureus α-toxin-induced cell death: predominant necrosis despite apoptotic caspase activation

I. H. Engels, K. Schulze-Osthoff, F. Essmann, 2003, Cell Death and Differentiation.

Apoptosis Resistance of MCF-7 Breast Carcinoma Cells to Ionizing Radiation Is Independent of p53 and Cell Cycle Control but Caused by the Lack of Caspase-3 and a Caffeine-Inhibitable Event

I. H. Engels, K. Schulze-Osthoff, F. Essmann, 2004, Cancer Research.

Ionizing radiation but not anticancer drugs causes cell cycle arrest and failure to activate the mitochondrial death pathway in MCF-7 breast carcinoma cells

I. H. Engels, A. Porter, K. Schulze-Osthoff, 2001, Oncogene.

Tributyltin (TBT) induces ultra-rapid caspase activation independent of apoptosome formation in human platelets

I. H. Engels, C. Belka, K. Schulze-Osthoff, 2003, Oncogene.

A Biochemical/Biophysical Assay Dyad for HTS-Compatible Triaging of Inhibitors of the HIV-1 Nef/Hck SH3 Interaction

S. Breuer, B. Torbett, S. Arold, 2013, Current chemical genomics and translational medicine.