Artis Klapars

发表

Synthesis of N-aryl hydrazides by copper-catalyzed coupling of hydrazides with aryl iodides.

S. Buchwald, M. Wolter, A. Klapars, 2001, Organic letters.

Investigating the Underappreciated Hydrolytic Instability of 1,8-Diazabicyclo[5.4.0]undec-7-ene and Related Unsaturated Nitrogenous Bases

Rebecca A. Arvary, A. Klapars, Alan M. Hyde, 2019, Organic Process Research & Development.

New Mechanism for Cinchona Alkaloid-Catalysis Allows for an Efficient Thiophosphorylation Reaction.

B. Sherry, A. Klapars, J. Qi, 2020, Journal of the American Chemical Society.

Enantioselective synthesis of an HCV NS5a antagonist.

Melodie Christensen, Ryan Cohen, Yonggang Chen, 2014, Organic letters.

A general and efficient copper catalyst for the amidation of aryl halides and the N-arylation of nitrogen heterocycles.

S. Buchwald, J. Antilla, A. Klapars, 2001, Journal of the American Chemical Society.

A highly efficient asymmetric synthesis of vernakalant.

M. Truppo, Eric Ashley, G. Beutner, 2014, Organic letters.

Copper-catalyzed domino halide exchange-cyanation of aryl bromides.

S. Buchwald, J. Zanon, A. Klapars, 2003, Journal of the American Chemical Society.

Activation of Pyridinium Salts for Electrophilic Acylation: a Method for Conversion of Pyridines into 3-Acylpyridines

E. Vedejs, Artis Klapars, 2004 .

Synthesis of medium ring nitrogen heterocycles via a tandem copper-catalyzed C-N bond formation-ring-expansion process.

Artis Klapars, S. Buchwald, Stephen L Buchwald, 2004, Journal of the American Chemical Society.

A general and efficient copper catalyst for the amidation of aryl halides.

S. Buchwald, A. Klapars, Xiaohua Huang, 2002, Journal of the American Chemical Society.

Copper-catalyzed halogen exchange in aryl halides: an aromatic Finkelstein reaction.

S. Buchwald, A. Klapars, Artis Klapars, 2002, Journal of the American Chemical Society.

Enantioselective, palladium-catalyzed α-arylation of N-Boc pyrrolidine: in situ react IR spectroscopic monitoring, scope, and synthetic applications.

P. O’Brien, G. Barker, A. Klapars, 2011, The Journal of organic chemistry.

Enantioselective, Palladium-Catalyzed α-Arylation of N-Boc-pyrrolidine

Cheng-yi Chen, A. Klapars, P. Dormer, 2006 .

Enantiocontrolled Synthesis of (1S,2S)-6-Desmethyl-(methylaziridino)mitosene

E. Vedejs, A. Klapars, F. Tucci, 2000 .

Enantioselective, Palladium-Catalyzed α-Arylation of N-Boc-pyrrolidine.

Cheng-yi Chen, A. Klapars, P. Dormer, 2006 .

Engineered Ribosyl-1-Kinase Enables Concise Synthesis of Molnupiravir, an Antiviral for COVID-19

T. Itoh, G. Murphy, K. Maloney, 2021, ACS central science.

Enantioselective Pd-catalyzed alpha-arylation of N-Boc-pyrrolidine: the key to an efficient and practical synthesis of a glucokinase activator.

D. Zewge, Cheng-yi Chen, A. Klapars, 2008, The Journal of organic chemistry.

Copper-catalyzed coupling of alkylamines and aryl iodides: an efficient system even in an air atmosphere.

S. Buchwald, A. Klapars, F. Kwong, 2002, Organic letters.

Mild and Practical Method for the α-Arylation of Nitriles with Heteroaryl Halides

M. McLaughlin, Cheng-yi Chen, John Y. L. Chung, 2005 .

The copper-catalyzed N-arylation of indoles.

S. Buchwald, J. Antilla, A. Klapars, 2002, Journal of the American Chemical Society.

Unlocking the Potential of High-Throughput Experimentation for Electrochemistry with a Standardized Microscale Reactor

Michael K. Wismer, Dan Lehnherr, Jonas Rein, 2021, ACS central science.

Electrochemical Activation of Galactose Oxidase: Mechanistic Studies and Synthetic Applications

A. Fryszkowska, A. Klapars, N. Strotman, 2021 .

Biocatalytic oxidation of alcohols using galactose oxidase and a manganese(III) activator for the synthesis of islatravir.

A. Fryszkowska, A. Klapars, M. Huffman, 2021, Organic & biomolecular chemistry.

Multi-column ultra-high performance liquid chromatography screening with chaotropic agents and computer-assisted separation modeling enables process development of new drug substances.

E. Regalado, I. Mangion, Timothy Nowak, 2019, The Analyst.

Efficient synthesis of antiviral agent uprifosbuvir enabled by new synthetic methods†

Timothy J. Wright, Rebecca T. Ruck, Tyler A. Davis, 2021, Chemical science.

Expanding Pd-catalyzed C-N bond-forming processes: the first amidation of aryl sulfonates, aqueous amination, and complementarity with Cu-catalyzed reactions.

S. Buchwald, A. Klapars, Xiaohua Huang, 2003, Journal of the American Chemical Society.

Asymmetric Synthesis of N-Boc-(R)-Silaproline via Rh-Catalyzed Intramolecular Hydrosilylation of Dehydroalanine and Continuous Flow N-Alkylation.

John Y. L. Chung, A. Klapars, M. Shevlin, 2016, Organic letters.

Supercritical fluid chromatography-photodiode array detection-electrospray ionization mass spectrometry as a framework for impurity fate mapping in the development and manufacture of drug substances.

Robert Hartman, Artis Klapars, E. Regalado, 2018, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

A multifunctional catalyst that stereoselectively assembles prodrugs

Yining Ji, Louis-Charles Campeau, Rebecca T. Ruck, 2017, Science.

Sequence-specific DNA interstrand cross-linking by an aziridinomitosene in the absence of exogenous reductant.

Don L. Warner, E. Vedejs, S. Rink, 2005, Biochemistry.

Synthetic enantiopure aziridinomitosenes: preparation, reactivity, and DNA alkylation studies.

Don L. Warner, H. Kohn, Y. Na, 2003, Journal of the American Chemical Society.

Preparation of enamides via palladium-catalyzed amidation of enol tosylates.

R. Volante, Cheng-yi Chen, A. Klapars, 2005, Organic letters.