Karsten Kretschmer

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Foxp3 occupancy and regulation of key target genes during T-cell stimulation

Ernest Fraenkel, Kenzie D. MacIsaac, Stuart S. Levine, 2007, Nature.

Induction of B-cell development in adult mice reveals the ability of bone marrow to produce B-1a cells.

A. Waisman, K. Kretschmer, M. Reth, 2009, Blood.

Affinity for self antigen selects regulatory T cells with distinct functional properties

K. Kretschmer, L. Terracciano, E. Palmer, 2016, Nature Immunology.

Induced miR‐99a expression represses Mtor cooperatively with miR‐150 to promote regulatory T‐cell differentiation

K. Kretschmer, L. Klein, K. Ansel, 2015, The EMBO journal.

Induced miR-99 a expression represses Mtor cooperatively with miR-150 to promote regulatory T-cell differentiation

K. Kretschmer, L. Klein, K. Ansel, 2015 .

Inducing and expanding regulatory T cell populations by foreign antigen

M. Nussenzweig, K. Kretschmer, H. Boehmer, 2005, Nature Immunology.

DNA methylation controls Foxp3 gene expression

K. Kretschmer, U. Baron, J. Polansky, 2008, European journal of immunology.

DEC205+ Dendritic Cell–Targeted Tolerogenic Vaccination Promotes Immune Tolerance in Experimental Autoimmune Arthritis

W. van Eden, K. Kretschmer, C. Keijzer, 2015, The Journal of Immunology.

Active Demethylation of the Foxp3 Locus Leads to the Generation of Stable Regulatory T Cells within the Thymus

R. Geffers, J. Walter, K. Kretschmer, 2013, The Journal of Immunology.

Identification of an immediate Foxp3− precursor to Foxp3+ regulatory T cells in peripheral lymphoid organs of nonmanipulated mice

Pei-Yun Tsai, K. Kretschmer, J. Riewaldt, 2010, The Journal of experimental medicine.

Severe Developmental B Lymphopoietic Defects in Foxp3-Deficient Mice are Refractory to Adoptive Regulatory T Cell Therapy

K. Kretschmer, S. Weiss, A. Garbe, 2012, Front. Immun..

Critical Role of TGF-β and IL-2 Receptor Signaling in Foxp3 Induction by an Inhibitor of DNA Methylation

K. Kretschmer, A. Garbe, Sebastian Dohnke, 2018, Front. Immunol..

IL-7 Abrogates Suppressive Activity of Human CD4+CD25+FOXP3+ Regulatory T Cells and Allows Expansion of Alloreactive and Autoreactive T Cells

E. Bonifacio, K. Kretschmer, Anne-Kristin Heninger, 2012, The Journal of Immunology.

Regulatory T + FOXP 3 + CD 25 + Human CD 4 IL-7 Abrogates Suppressive Activity of Bonifacio and Paolo Monti

K. Kretschmer, C. Petzold, Nicole Huebel, 2012 .

Germline transcripts of immunoglobulin light chain variable regions are structurally diverse and differentially expressed.

K. Kretschmer, S. Weiss, A. Rolink, 2003, Molecular immunology.

Small-molecule RORγt antagonists inhibit T helper 17 cell transcriptional network by divergent mechanisms.

Mark S. Sundrud, A. Regev, R. Young, 2014, Immunity.

Retargeting of Human Regulatory T Cells by Single-Chain Bispecific Antibodies

K. Kretschmer, G. Ehninger, A. Temme, 2012, The Journal of Immunology.

Continuous T cell receptor signals maintain a functional regulatory T cell pool.

Marco Y. Hein, K. Kretschmer, L. Klein, 2014, Immunity.

Foxp3+ Regulatory T Cells in Mouse Models of Type 1 Diabetes

K. Kretschmer, T. Sparwasser, Deepika Watts, 2013, Journal of diabetes research.

Peripherally Induced Treg: Mode, Stability, and Role in Specific Tolerance

K. Kretschmer, J. Polansky, H. Boehmer, 2008, Journal of Clinical Immunology.

Chapter 2 FoxP 3 and Regulatory T Cells

K. Kretschmer, H. Boehmer, I. Apostolou, 2009 .

FoxP3 and Regulatory T Cells

K. Kretschmer, H. Boehmer, I. Apostolou, 2008 .

Retinoic acid can enhance conversion of naive into regulatory T cells independently of secreted cytokines

K. Kretschmer, C. Stuelten, P. Li, 2009, The Journal of experimental medicine.

Kruppel-like Factor KLF10 Targets Transforming Growth Factor-β1 to Regulate CD4+CD25− T Cells and T Regulatory Cells*

P. Libby, K. Kretschmer, G. Hansson, 2009, The Journal of Biological Chemistry.

The Mucosal Adjuvant Macrophage-Activating Lipopeptide-2 Directly Stimulates B Lymphocytes via the TLR2 without the Need of Accessory Cells 1

K. Kretschmer, C. Guzmán, S. Weiss, 2005, The Journal of Immunology.

TLR 2 without the Need of Accessory Cells Directly Stimulates B Lymphocytes via the Macrophage-Activating Lipopeptide-2 The Mucosal Adjuvant and

K. Kretschmer, C. Guzmán, S. Weiss, 2005 .

Genomic definition of multiple ex vivo regulatory T cell subphenotypes

C. Benoist, D. Mathis, M. Feuerer, 2010, Proceedings of the National Academy of Sciences.

T Lymphocytes Contribute to the Control of Baseline Neural Precursor Cell Proliferation but Not the Exercise-Induced Up-Regulation of Adult Hippocampal Neurogenesis

G. Kempermann, K. Kretschmer, T. Walker, 2018, Front. Immunol..

Myelin-specific T helper 17 cells promote adult hippocampal neurogenesis through indirect mechanisms.

G. Kempermann, K. Kretschmer, S. Schallenberg, 2014, F1000Research.

Myelin-specific T helper 17 cells promote adult hippocampal neurogenesis through indirect mechanisms

G. Kempermann, K. Kretschmer, S. Schallenberg, 2017, F1000Research.

The Selection of Marginal Zone B Cells Differs from That of B-1a Cells 1

K. Kretschmer, S. Weiss, R. Hoffmann, 2003, The Journal of Immunology.

Differs from That of B-1a Cells The Selection of Marginal Zone B Cells

K. Kretschmer, S. Weiss, R. Hoffmann, 2003 .

Induced B Cell Development in Adult Mice

F. Klawonn, K. Kretschmer, S. Weiss, 2018, Front. Immunol..

Strong antigenic selection shaping the immunoglobulin heavy chain repertoire of B‐1a lymphocytes in λ2315 transgenic mice

K. Kretschmer, S. Weiss, H. Engel, 2002 .

Selective ablation of thymic and peripheral Foxp3+ regulatory T cell development

Susan M. Schlenner, D. Voehringer, A. Yilmazer, 2023, bioRxiv.

Distinct Roles of β-Cell Mass and Function During Type 1 Diabetes Onset and Remission

C. Cohrs, I. Roeder, Chunguang Chen, 2015, Diabetes.

Minimum Information about T Regulatory Cells: A Step toward Reproducibility and Standardization

D. Hafler, J. Bluestone, J. Isaacs, 2018, Front. Immunol..

Title Minimum Information about T Regulatory Cells : A Step toward Reproducibility and Standardization Permalink

D. Hafler, J. Bluestone, J. Isaacs, 2018 .

Promoting tolerance to proteolipid protein-induced experimental autoimmune encephalomyelitis through targeting dendritic cells

D. Keskin, J. Strominger, K. Kretschmer, 2010, Proceedings of the National Academy of Sciences.

Targeting DEC-205−DCIR2+ dendritic cells promotes immunological tolerance in proteolipid protein-induced experimental autoimmune encephalomyelitis

D. Keskin, D. Mooney, B. Diamond, 2018, Molecular Medicine.

De novo production of antigen-specific suppressor cells in vivo

T. Heng, K. Kretschmer, H. Boehmer, 2006, Nature Protocols.

Targeted antigen delivery to DEC-205⁺ dendritic cells for tolerogenic vaccination.

K. Kretschmer, Joel N.H. Stern, C. Petzold, 2012, The review of diabetic studies : RDS.

Dendritic cell-targeted pancreatic beta-cell antigen leads to conversion of self-reactive CD4(+) T cells into regulatory T cells and promotes immunotolerance in NOD mice.

K. Kretschmer, J. Riewaldt, C. Petzold, 2010, The review of diabetic studies : RDS.

Targeting DEC-205−DCIR2+ dendritic cells promotes immunological tolerance in proteolipid protein-induced experimental autoimmune encephalomyelitis

D. Keskin, D. Mooney, B. Diamond, 2018, Molecular Medicine.

Pancreatic NOD beta cells express MHC class II protein and the frequency of I-Ag7 mRNA-expressing beta cells strongly increases during progression to autoimmune diabetes

J. Lauber, W. Scherbaum, J. Buer, 2003, Diabetologia.

Regulatory T Cell-Based Immunotherapy: Prospects of Antigen-Specific Tolerance Induction

K. Kretschmer, J. Riewaldt, C. Petzold, 2013 .

Single-Chain Bispecific Antibodies Retargeting of Human Regulatory T Cells by

K. Kretschmer, G. Ehninger, A. Temme, 2011 .

Foxp3+ Regulatory T Cells in Bone and Hematopoietic Homeostasis

K. Kretschmer, Luise Fischer, A. Garbe, 2019, Front. Endocrinol..

New insight into type 1 diabetes development: resolving early diabetogenic CD4+ T cell responses that precede seroconversion.

K. Kretschmer, S. Schallenberg, Karsten Kretschmer, 2018, Annals of translational medicine.

Making regulatory T cells with defined antigen specificity: role in autoimmunity and cancer

K. Kretschmer, E. Jaeckel, H. von Boehmer, 2006, Immunological reviews.

Role of Dynamic Actin Cytoskeleton Remodeling in Foxp3+ Regulatory T Cell Development and Function: Implications for Osteoclastogenesis

R. Jessberger, K. Kretschmer, T. Kurth, 2022, Frontiers in Immunology.

Disturbed sleep in bipolar disorder is related to an elevation of IL-6 in peripheral monocytes.

A. Pfennig, K. Kretschmer, P. Ritter, 2013, Medical hypotheses.

IL-7 Abrogates Suppressive Activity of Human CD4+CD25+FOXP3+ Regulatory T Cells and Allows Expansion of Alloreactive and Autoreactive T Cells

E. Bonifacio, Anne-Kristin Heninger, A. Theil, 2012, The Journal of Immunology.

Affinity for self antigen selects regulatory T cells with distinct functional properties

L. Terracciano, E. Palmer, G. Anderson, 2016, Nature Immunology.

Maintenance of Peritoneal B-1a Lymphocytes in the Absence of the Spleen1

T. Greten, K. Kretschmer, S. Weiss, 2004, The Journal of Immunology.

Approaches to Discriminate Naturally Induced Foxp3+ Treg cells of Intra- and Extrathymic Origin: Helios, Neuropilin-1, and Foxp3RFP/GFP

K. Kretschmer, M. Schreiber, Luise Fischer, 2018 .

Ar Ticle Identification of an Immediate Foxp3  Precursor to Foxp3 + Regulatory T Cells in Peripheral Lymphoid Organs of Nonmanipulated Mice

Pei-Yun Tsai, J. Riewaldt, S. Schallenberg, 2022 .

Transient Depletion of Foxp3+ Regulatory T Cells Selectively Promotes Aggressive β Cell Autoimmunity in Genetically Susceptible DEREG Mice

E. Bonifacio, K. Kretschmer, T. Sparwasser, 2021, Frontiers in Immunology.

Advantages of Foxp3+ regulatory T cell depletion using DEREG mice

K. Kretschmer, B. Rouse, M. Kopf, 2014, Immunity, inflammation and disease.

Advantages of Foxp 3 + regulatory T cell depletion using DEREG mice Advantages of Foxp 3 + regulatory T cell depletion

K. Kretschmer, B. Rouse, M. Kopf, 2014 .

Fluorochrome‐based definition of naturally occurring Foxp3+ regulatory T cells of intra‐ and extrathymic origin

R. Geffers, K. Kretschmer, D. Bruder, 2014, European journal of immunology.

Vagaries of Fluorochrome Reporter Gene Expression in Foxp3+ Regulatory T Cells

Pei-Yun Tsai, K. Kretschmer, T. Sparwasser, 2012, PloS one.

RelB Deficiency in Dendritic Cells Protects from Autoimmune Inflammation Due to Spontaneous Accumulation of Tissue T Regulatory Cells

K. Kretschmer, G. Garg, T. Korn, 2019, The Journal of Immunology.

Induction of B-cell development in adult mice reveals the ability of bone marrow to produce B-1a cells.

A. Waisman, M. Reth, E. Hobeika, 2009, Blood.

B‐1a cells are imprinted by the microenvironment in spleen and peritoneum

K. Kretschmer, S. Weiss, Sandra Düber, 2007, European journal of immunology.

Inducible IL-7 Hyperexpression Influences Lymphocyte Homeostasis and Function and Increases Allograft Rejection

E. Bonifacio, K. Kretschmer, M. Schreiber, 2019, Front. Immunol..

Antibody Repertoire and Gene Expression Profile: Implications for Different Developmental and Functional Traits of Splenic and Peritoneal B-1 Lymphocytes 1

K. Kretschmer, S. Weiss, R. Hoffmann, 2003, The Journal of Immunology.

Strong antigenic selection shaping the immunoglobulin heavy chain repertoire of B-1a lymphocytes in lambda 2(315) transgenic mice.

S. Weiss, H. Engel, Karsten Kretschmer, 2002, European journal of immunology.