J. O’Brien

发表

Synthesis, characterization and monoamine transporter activity of the new psychoactive substance mexedrone and its N-methoxy positional isomer, N-methoxymephedrone.

B. Twamley, S. Brandt, J. Partilla, 2017, Drug testing and analysis.

Synthesis, analytical characterization, and monoamine transporter activity of the new psychoactive substance 4-methylphenmetrazine (4-MPM), with differentiation from its ortho- and meta- positional isomers.

B. Twamley, S. Brandt, D. Walther, 2018, Drug testing and analysis.

Test purchase, synthesis and characterization of 3-fluorophenmetrazine (3-FPM) and differentiation from its ortho- and para-substituted isomers.

Brian Talbot, Brendan Twamley, Geraldine Dowling, 2017, Drug testing and analysis.

Design, Synthesis and Biochemical Evaluation of Novel Ethanoanthracenes and Related Compounds to Target Burkitt’s Lymphoma

D. Williams, M. Meegan, B. Twamley, 2020, Pharmaceuticals.

Fluorescent sensing of pyrophosphate and bis-carboxylates with charge neutral PET chemosensors.

T. Gunnlaugsson, A. P. Davis, J. O'Brien, 2002, Organic letters.

The syntheses, characterization and in vitro metabolism of nitracaine, methoxypiperamide and mephtetramine.

E. A. Gardner, K. Scott, J. O'Brien, 2014, Drug testing and analysis.

Synthesis and in vitro toxicity of 4-MTA, its characteristic clandestine synthesis byproducts and related sulfur substituted alpha-alkylthioamphetamines.

D. Williams, M. Meegan, S. Cloonan, 2010, Bioorganic & medicinal chemistry.

Fixing the Conformation of Calix[4]arenes: When Are Three Carbons Not Enough?

C. Macdonald, S. E. Matthews, S. Vidal, 2018, Chemistry.

Identification of (2-aminopropyl)indole positional isomers in forensic samples.

K. Scott, J. O'Brien, P. Kavanagh, 2014, Drug testing and analysis.

The application of chiroptical spectroscopy (circular dichroism) in quantifying binding events in lanthanide directed synthesis of chiral luminescent self-assembly structures

Jonathan A. Kitchen, T. Gunnlaugsson, B. Twamley, 2014, Chemical science.

Test purchase, identification and synthesis of 2-amino-1-(4-bromo-2, 5-dimethoxyphenyl)ethan-1-one (bk-2C-B).

B. Twamley, S. Brandt, J. O'Brien, 2015, Drug testing and analysis.

Asymmetric acyl-transfer promoted by readily assembled chiral 4-N,N-dialkylaminopyridine derivatives.

T. McCabe, G. Watson, S. Connon, 2006, Organic & biomolecular chemistry.

The analysis of substituted cathinones. Part 3. Synthesis and characterisation of 2,3-methylenedioxy substituted cathinones.

Cora O'Donnell, Rachel Christie, Pierce Kavanagh, 2012, Forensic science international.

The analysis of substituted cathinones. Part 2: an investigation into the phenylacetone based isomers of 4-methylmethcathinone and N-ethylcathinone.

J. O'Brien, P. Kavanagh, S. McDermott, 2011, Forensic science international.

The analysis of substituted cathinones. Part 1: chemical analysis of 2-, 3- and 4-methylmethcathinone.

J. O'Brien, P. Kavanagh, S. McDermott, 2011, Forensic science international.

Elucidating Atropisomerism in Nonplanar Porphyrins with Tunable Supramolecular Complexes

M. Senge, D. Gibbons, Karolis Norvaiša, 2020, Chemistry.

Test purchase, synthesis, and characterization of 2-methoxydiphenidine (MXP) and differentiation from its meta- and para-substituted isomers.

J. Wallach, S. Brandt, J. O'Brien, 2016, Drug testing and analysis.

Lanthanide directed self-assembly of highly luminescent supramolecular "peptide" bundles from α-amino acid functionalized 2,6-bis(1,2,3-triazol-4-yl)pyridine (btp) ligands.

Jonathan A. Kitchen, T. Gunnlaugsson, R. Peacock, 2015, Inorganic chemistry.

Metal-directed synthesis of enantiomerially pure dimetallic lanthanide luminescent triple-stranded helicates.

C. McCoy, T. Gunnlaugsson, R. Peacock, 2009, Journal of the American Chemical Society.

Self-assembly of chiral luminescent lanthanide coordination bundles.

T. Gunnlaugsson, T. McCabe, P. Kruger, 2007, Journal of the American Chemical Society.

Electrostatic interactions play an essential role in the binding of oleic acid with α‐lactalbumin in the HAMLET‐like complex: A study using charge‐specific chemical modifications

C. Svanborg, J. O'Brien, S. Min, 2013, Proteins.

Characterization of a novel and potentially lethal designer drug (±)-cis-para-methyl-4-methylaminorex (4,4'-DMAR, or 'Serotoni').

N. Dempster, B. Twamley, Kuldip Singh, 2014, Drug testing and analysis.

Outsmarted by nootropics? An investigation into the thermal degradation of modafinil, modafinic acid, adrafinil, CRL-40,940 and CRL-40,941 in the GC injector: formation of 1,1,2,2-tetraphenylethane and its tetra fluoro analog.

B. Twamley, S. Brandt, J. O'Brien, 2017, Drug testing and analysis.

Synthesis, spectroscopic and biological studies of a fluorescent Pt(II) (terpy) based 1,8-naphthalimide conjugate as a DNA targeting agent.

Jonathan A. Kitchen, T. Gunnlaugsson, D. Williams, 2013, Chemical communications.

Colorimetric sensing of anions in aqueous solution using a charge neutral, cleft-like, amidothiourea receptor: tilting the balance between hydrogen bonding and deprotonation in anion recognition.

T. Gunnlaugsson, T. McCabe, J. O'Brien, 2008, Organic & biomolecular chemistry.

Synthesis and photophysical evaluation of charge neutral thiourea or urea based fluorescent PET sensors for bis-carboxylates and pyrophosphate.

T. Gunnlaugsson, A. P. Davis, J. O'Brien, 2005, Organic & biomolecular chemistry.

α-Lactalbumin, Engineered to be Non-Native and Inactive, Kills Tumor Cells When in Complex with Oleic Acid: A New Biological Function Resulting from Partial Unfolding

Y. Lim, C. Svanborg, K. Mok, 2010 .

A folded [2 × 2] metallo-supramolecular grid from a bis-tridentate (1,2,3-triazol-4-yl)-picolinamide (tzpa) ligand.

M. Ruether, T. Gunnlaugsson, J. O'Brien, 2017, Dalton transactions.

The syntheses and characterization 3β-(4-fluorobenzoyloxy)tropane (fluorotropacocaine) and its 3α isomer.

J. O'Brien, P. Kavanagh, S. McDermott, 2012, Drug testing and analysis.

β-Lactam-host defence peptide conjugates as antibiotic prodrug candidates targeting resistant bacteria

M. Devocelle, T. Smyth, H. Humphreys, 2012 .

'Smoking' mephedrone: the identification of the pyrolysis products of 4-methylmethcathinone hydrochloride.

J. O'Brien, P. Kavanagh, S. McDermott, 2013, Drug testing and analysis.

The synthesis, N-alkylation and epimerisation study of a phthaloyl derived thiazolidine

T. Gunnlaugsson, T. McCabe, Emma B. Veale, 2008 .

Preparation and characterisation of novel chlorothiazide potassium solid-state salt forms: Intermolecular self assembly suprastructures.

A. Healy, T. McCabe, O. Corrigan, 2011, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Preparation and solid state characterisation of chlorothiazide sodium intermolecular self-assembly suprastructure.

A. Healy, T. McCabe, O. Corrigan, 2010, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

The Psilocin (4‐hydroxy‐N,N‐dimethyltryptamine) and Bufotenine (5‐hydroxy‐N,N‐dimethyltryptamine) Case: Ensuring the Correct Isomer has Been Identified

J. O'Brien, P. Kavanagh, Brian Talbot, 2020, Journal of forensic sciences.

The effect of the linker size in C2-symmetrical chiral ligands on the self-assembly formation of luminescent triple-stranded di-metallic Eu(iii) helicates in solution.

C. McCoy, T. Gunnlaugsson, Komala Pandurangan, 2018, Dalton transactions.

Application of 2D EXSY and qNMR Spectroscopy for Diastereomeric Excess Determination Following Chiral Resolution of β‐Lactams

M. Meegan, N. O’Boyle, Cristina Trujillo, 2022, ChemistryOpen.

Sulphide as a leaving group: highly stereoselective bromination of alkyl phenyl sulphides† †Electronic supplementary information (ESI) available: Experimental procedures and spectroscopic characterization for all new compounds, including details of NMR experiments and racemisation study. See DOI: 10

Mauro F. A. Adamo, M. Ruether, H. Ibrahim, 2019, Chemical science.

Synthesis, analytical characterization, and monoamine transporter activity of the new psychoactive substance 4-methylphenmetrazine (4-MPM), with differentiation from its ortho- and meta- positional isomers.

B. Twamley, S. Brandt, D. Walther, 2018, Drug testing and analysis.

Effect on pKa of metal-bound water molecules in lanthanide ion-induced cyclen "cavities".

T. Gunnlaugsson, M. Nieuwenhuyzen, D. Brougham, 2004, Organic letters.

Synthesis, structural and biological evaluation of GlyAla based lanthanide macrocyclic conjugates as supramolecular ribonuclease mimics

T. Gunnlaugsson, M. Nieuwenhuyzen, R. Davies, 2003 .

Cyclen based lanthanide ion ribonuclease mimics: the effect of pyridine cofactors upon phosphodiester HPNP hydrolysis

T. Gunnlaugsson, T. McCabe, P. Kruger, 2005 .

THE ORGANIC PHOSPHORUS COMPOSITION OF AN IRISH GRASSLAND SOIL

H. Tunney, D. Jeffrey, D. Bourke, 2022, Biology and Environment: Proceedings of the Royal Irish Academy.

An approach to shortening the timeframe between the emergence of new compounds on the drugs market and the availability of reference standards: The microscale syntheses of nitrazolam and clonazolam for use as reference materials, utilizing polymer-supported reagents.

B. Twamley, S. Brandt, Geraldine Dowling, 2018, Drug testing and analysis.