Phyllissa Schmiedlin‐Ren

发表

Expression of enzymatically active CYP3A4 by Caco-2 cells grown on extracellular matrix-coated permeable supports in the presence of 1alpha,25-dihydroxyvitamin D3.

P. Watkins, K. Thummel, P. Schmiedlin-Ren, 1997, Molecular pharmacology.

Role of intestinal P‐glycoprotein (mdr1) in interpatient variation in the oral bioavailability of cyclosporine

Morton B. Brown, P. Watkins, L. Benet, 1997, Clinical pharmacology and therapeutics.

Identification of rifampin-inducible P450IIIA4 (CYP3A4) in human small bowel enterocytes.

J. Kolars, P. Watkins, J. Schuetz, 1992, The Journal of clinical investigation.

Induction of CYP3A4 by 1 alpha,25-dihydroxyvitamin D3 is human cell line-specific and is unlikely to involve pregnane X receptor.

P. Watkins, K. Thummel, P. Schmiedlin-Ren, 2001, Drug metabolism and disposition: the biological fate of chemicals.

Aflatoxin B1-adduct formation in rat and human small bowel enterocytes.

J. Kolars, P. Watkins, P. Schmiedlin-Ren, 1994, Gastroenterology.

Resveratrol has antiinflammatory and antifibrotic effects in the peptidoglycan‐polysaccharide rat model of Crohn's disease

Ji Zhu, G. Christman, J. Adler, 2012, Inflammatory bowel diseases.

Resveratrol causes cell cycle arrest, decreased collagen synthesis, and apoptosis in rat intestinal smooth muscle cells.

J. S. Mathias, G. Christman, E. Zimmermann, 2012, American journal of physiology. Gastrointestinal and liver physiology.

Selective expression of CYP3A5 and not CYP3A4 in human blood.

P. Watkins, K. Thummel, P. Schmiedlin-Ren, 1996, Pharmacogenetics.

CYP3A gene expression in human gut epithelium.

J. Kolars, P. Watkins, S. Wrighton, 1994, Pharmacogenetics.

Cytochrome P-450 1A1 expression in human small bowel: interindividual variation and inhibition by ketoconazole.

P. Watkins, P. Schmiedlin-Ren, M. Paine, 1999, Drug metabolism and disposition: the biological fate of chemicals.

Magnetization transfer helps detect intestinal fibrosis in an animal model of Crohn disease.

H. Hussain, P. Higgins, S. Swanson, 2011, Radiology.

IGF-I increases IGFBP-5 and collagen alpha1(I) mRNAs by the MAPK pathway in rat intestinal smooth muscle cells.

K. Bitar, G. Christman, E. Zimmermann, 2004, American journal of physiology. Gastrointestinal and liver physiology.

First-pass midazolam metabolism catalyzed by 1alpha,25-dihydroxy vitamin D3-modified Caco-2 cell monolayers.

P. Watkins, S. Wrighton, D. Shen, 1999, The Journal of pharmacology and experimental therapeutics.

Anti-TNFα alters the natural history of experimental Crohn's disease in rats when begun early, but not late, in disease.

J. Adler, E. Zimmermann, L. Reingold, 2016, American journal of physiology. Gastrointestinal and liver physiology.

Mechanisms of enhanced oral availability of CYP3A4 substrates by grapefruit constituents. Decreased enterocyte CYP3A4 concentration and mechanism-based inactivation by furanocoumarins.

P. Watkins, P. Woster, K. He, 1997, Drug metabolism and disposition: the biological fate of chemicals.

Cultured adult rat jejunal explants as a model for studying regulation of CYP3A.

J. Kolars, P. Watkins, P. Schmiedlin-Ren, 1993, Biochemical Pharmacology.

Anti–Tumor Necrosis Factor &agr; Prevents Bowel Fibrosis Assessed by Messenger RNA, Histology, and Magnetization Transfer MRI in Rats With Crohn's Disease

S. Swanson, D. Shealy, J. Adler, 2013, Inflammatory bowel diseases.

OF ENHANCED ORAL AVAILABILITY OF CYP 3 A 4 SUBSTRATES BY GRAPEFRUIT CONSTITUENTS Decreased enterocyte CYP 3 A 4 concentration and mechanism-based inactivation by furanocoumarins

P. Watkins, P. Woster, K. Thummel, 1997 .

Identification of rifampin-inducible P 450 IIIA 4 ( CYP 3 A 4 ) in human small bowel enterocytes

J. Kolars, P. Watkins, J. Schuetz, 2013 .

Adenoviral transduction of enterocytes and M-cells using in vitro models based on Caco-2 cells: the coxsackievirus and adenovirus receptor (CAR) mediates both apical and basolateral transduction.

D. Fleisher, F. Kesisoglou, E. Zimmermann, 2010, Molecular pharmaceutics.

Restituting intestinal epithelial cells exhibit increased transducibility by adenoviral vectors

D. Fleisher, B. Roessler, F. Kesisoglou, 2006, The journal of gene medicine.

Increased Transduction of Human Intestinal Epithelial Cells by Adenoviral Vectors in Inflammatory Bowel Disease

W. Chey, B. Roessler, J. Barnett, 2005, Inflammatory bowel diseases.

CYCLOSPORINE METABOLISM BY P450IIIA IN RAT ENTEROCYTES—ANOTHER DETERMINANT OF ORAL BIOAVAILABILITY?

J. Kolars, P. Watkins, J. Voorhees, 1992, Transplantation.