H. Hengartner

发表

Fas and perforin pathways as major mechanisms of T cell-mediated cytotoxicity.

H Hengartner, S. Nagata, V. Depraetere, 1994, Science.

T cell priming versus T cell tolerance induced by synthetic peptides

H. Pircher, R. Zinkernagel, H. Hengartner, 1995, The Journal of experimental medicine.

A primitive T cell-independent mechanism of intestinal mucosal IgA responses to commensal bacteria.

R. Zinkernagel, A. Macpherson, H. Hengartner, 2000, Science.

Quantification of lymphocytic choriomeningitis virus with an immunological focus assay in 24- or 96-well plates.

R M Zinkernagel, H Hengartner, R. Zinkernagel, 1991, Journal of virological methods.

Molecular mechanisms of lymphocyte-mediated cytotoxicity and their role in immunological protection and pathogenesis in vivo.

R. Zinkernagel, H. Hengartner, B. Ledermann, 1996, Annual review of immunology.

Enhanced establishment of a virus carrier state in adult CD4+ T-cell-deficient mice

R. Zinkernagel, T. Mak, M. Battegay, 1994, Journal of virology.

Control of early viral and bacterial distribution and disease by natural antibodies.

R. Zinkernagel, T. Fehr, F. Brombacher, 1999, Science.

CD4+ T-cell induction and effector functions: a comparison of immunity against soluble antigens and viral infections.

R. Zinkernagel, A. Oxenius, H. Hengartner, 1998, Advances in immunology.

IL-12 is not required for induction of type 1 cytokine responses in viral infections.

R. Zinkernagel, A. Oxenius, H. Hengartner, 1999, Journal of immunology.

Escape of thymocytes and mature T cells from clonal deletion due to limiting tolerogen expression levels.

R. Zinkernagel, P. Ohashi, H. Hengartner, 1994, Cellular immunology.

Vaccination with two different vaccinia recombinant viruses: long-term inhibition of secondary vaccination.

R. Zinkernagel, T. Kündig, C. Kalberer, 1993, Vaccine.

On Immunity Against Infections and Vaccines: Credo 2004

R. Zinkernagel, R. M. Zinkernagel, Rolf M. Zinkernagel, 2004, Scandinavian journal of immunology.

Fibroblasts as efficient antigen-presenting cells in lymphoid organs.

M. Battegay, T. Kündig, M. Bachmann, 1995, Science.

A critical role for neutralizing-antibody-producing B cells, CD4(+) T cells, and interferons in persistent and acute infections of mice with lymphocytic choriomeningitis virus: implications for adoptive immunotherapy of virus carriers.

R M Zinkernagel, H Hengartner, R. Zinkernagel, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Viral persistence in vivo through selection of neutralizing antibody-escape variants.

P. Klenerman, R. Zinkernagel, L. Hunziker, 2000, Proceedings of the National Academy of Sciences of the United States of America.

Antiviral immunity.

R. Zinkernagel, H. Hengartner, H. Hengartner, 1997, Immunology today.

Detection of perforin and granzyme A mRNA in infiltrating cells during infection of mice with lymphocytic choriomeningitis virus

R. Zinkernagel, E. Podack, H. Hengartner, 1989, European journal of immunology.

Decreased tumor surveillance in perforin-deficient mice

R. Zinkernagel, C. Melief, H. Hengartner, 1996, The Journal of experimental medicine.

T cell development and repertoire of mice expressing a single T cell receptor α chain

H. Pircher, A. Hayday, M. Owen, 1995, European journal of immunology.

Virus-triggered acquired immunodeficiency by cytotoxic T-cell-dependent destruction of antigen-presenting cells and lymph follicle structure.

R. Zinkernagel, H. Hengartner, B. Odermatt, 1991, Proceedings of the National Academy of Sciences of the United States of America.

The influence of antigen organization on B cell responsiveness.

R. Zinkernagel, T. Kündig, M. Bachmann, 1993, Science.

Major histocompatibility complex-linked susceptibility or resistance to disease caused by a noncytopathic virus varies with the disease parameter evaluated

R. Zinkernagel, H. Hengartner, T. Leist, 1989, The Journal of experimental medicine.

Comparison of activation versus induction of unresponsiveness of virus-specific CD4+ and CD8+ T cells upon acute versus persistent viral infection.

R. Zinkernagel, A. Oxenius, H. Hengartner, 1998, Immunity.

T-cell-mediated immunopathology versus direct cytolysis by virus: implications for HIV and AIDS.

R. Zinkernagel, H. Hengartner, H. Hengartner, 1994, Immunology today.

Antiviral cytotoxic T cell response induced by in vivo priming with a free synthetic peptide

R. Zinkernagel, H. Hengartner, P. Aichele, 1990, The Journal of experimental medicine.

Clearance of lymphocytic choriomeningitis virus in antibody- and B-cell-deprived mice

R. Zinkernagel, H. Bazin, H. Hengartner, 1988, Journal of virology.

Persistence of lymphocytic choriomeningitis virus at very low levels in immune mice.

P. Klenerman, R. Zinkernagel, L. Hunziker, 1999, Proceedings of the National Academy of Sciences of the United States of America.

Lysis of infected cells in vivo by antiviral cytolytic T cells demonstrated by release of cell internal viral proteins

R. Zinkernagel, M. Battegay, D. Speiser, 1993, European journal of immunology.

Immune responses in interleukin-2-deficient mice.

R. Zinkernagel, T. Kündig, M. Bachmann, 1993, Science.

Treatment of murine L1210 lymphoid leukemia and melanoma B16 with lipophilic cytosine arabinoside prodrugs incorporated into unilamellar liposomes

R. Schwendener, W. Rubas, A. Supersaxo, 1986, International journal of cancer.

Peptide antigen treatment of naive and virus-immune mice: antigen-specific tolerance versus immunopathology.

R M Zinkernagel, H Hengartner, H. Pircher, 1997, Immunity.

Vaccination or tolerance to prevent diabetes

R. Zinkernagel, P. Ohashi, H. Hengartner, 1992, European journal of immunology.

Expression of CD4 can confer major histocompatibility complex class II‐associated superantigen reactivity upon a T cell receptor derived from a CD8‐dependent cytotoxic T lymphocyte clone

T. Mak, P. Ohashi, V. Wallace, 1990, European journal of immunology.

Peptide-induced antiviral protection by cytotoxic T cells.

R. Zinkernagel, H. Hengartner, M. Schulz, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Immune surveillance against a solid tumor fails because of immunological ignorance.

P. Klenerman, R. Zinkernagel, B. Ludewig, 1999, Proceedings of the National Academy of Sciences of the United States of America.

Discrepancy between in vitro measurable and in vivo virus neutralizing cytotoxic T cell reactivities. Low T cell receptor specificity and avidity sufficient for in vitro proliferation or cytotoxicity to peptide-coated target cells but not for in vivo protection.

R. Zinkernagel, D. Speiser, H. Hengartner, 1992, Journal of immunology.

Protective long-term antibody memory by antigen-driven and T help-dependent differentiation of long-lived memory B cells to short-lived plasma cells independent of secondary lymphoid organs.

R. Zinkernagel, H. Hengartner, S. Sierro, 2000, Proceedings of the National Academy of Sciences of the United States of America.

T cell tolerance to Mlsa encoded antigens in T cell receptor V beta 8.1 chain transgenic mice.

H. Pircher, R. Zinkernagel, T. Mak, 1989, The EMBO journal.

T and B cell Tolerance and Responses to Viral Antigens in Transgenic Mice: Implications for the Pathogenesis of Autoimmune versus Immunopathological Disease

H. Pircher, R. Zinkernagel, T. Mak, 1991, Immunological reviews.

Transgenic Animal Models for Virus‐Induced Autoimmune Diseases

R. Zinkernagel, B. Ludewig, H. Hengartner, 2000, Experimental physiology.

Persistence of lymphocytic choriomeningitis virus at very low levels in immune mice.

P. Klenerman, R. Zinkernagel, L. Hunziker, 1999, Proceedings of the National Academy of Sciences of the United States of America.

Impairment and delay of neutralizing antiviral antibody responses by virus-specific cytotoxic T cells.

R M Zinkernagel, H Hengartner, R. Zinkernagel, 1993, Journal of immunology.

Antivirally protective cytotoxic T cell memory to lymphocytic choriomeningitis virus is governed by persisting antigen

R. Zinkernagel, T. Kündig, H. Hengartner, 1992, The Journal of experimental medicine.

Restriction fine specificity of long‐term, hapten‐specific cytotoxic T cell clones: analysis with H‐2Kbm‐mutant mice and H‐2Kb‐specific monoclonal antibodies

H. Pircher, G. Hämmerling, H. Hengartner, 1984, European journal of immunology.

Enhanced positive selection of a transgenic TCR by a restriction element that does not permit negative selection.

H. Pircher, R. Zinkernagel, P. Ohashi, 1993, International Immunology.

Decreased tumor surveillance in perforin-deficient mice

W. Lutz, Ferry Ossendorpfl, Toesfi SpirosVamvakas, 1996, The Journal of experimental medicine.

Engagement of the T-cell receptor during positive selection in the thymus down-regulates RAG-1 expression.

H. Pircher, T. Rülicke, H. Hengartner, 1992, Proceedings of the National Academy of Sciences of the United States of America.

Linking immune-mediated arterial inflammation and cholesterol-induced atherosclerosis in a transgenic mouse model.

M. Kurrer, R. Zinkernagel, B. Ludewig, 2000, Proceedings of the National Academy of Sciences of the United States of America.

Development of insulitis without diabetes in transgenic mice lacking perforin-dependent cytotoxicity

R. Zinkernagel, P. Ohashi, H. Hengartner, 1996, The Journal of experimental medicine.

Induction of long-lived germinal centers associated with persisting antigen after viral infection

R. Zinkernagel, M. Bachmann, H. Hengartner, 1996, The Journal of experimental medicine.

Antiviral protection by vesicular stomatitis virus-specific antibodies in alpha/beta interferon receptor-deficient mice

R. Zinkernagel, U. Steinhoff, M. Aguet, 1995, Journal of virology.

Susceptibility to lymphocytic choriomeningitis virus isolates correlates directly with early and high cytotoxic T cell activity, as well as with footpad swelling reaction, and all three are regulated by H-2D

R. Zinkernagel, H. Hengartner, T. Leist, 1985, The Journal of experimental medicine.

Suppression by cyclosporin A of murine T-cell-mediated immunity against viruses in vivo and in vitro.

R. Zinkernagel, H. Hengartner, A. Cerny, 1985, Cellular immunology.

Virus-induced Transient Bone Marrow Aplasia: Major Role of Interferon- (cid:97) / (cid:98) during Acute Infection with the Noncytopathic Lymphocytic Choriomeningitis Virus

R. Zinkernagel, Daniel Binder, H. Hengartner, 1997 .

Morphologic analysis of human lymphokine‐activated killer (LAK) cells

R. Stahel, H. Hengartner, L. Jost, 1990, International journal of cancer.

A central role of perforin in cytolysis?

E. Podack, H. Hengartner, M. Lichtenheld, 1991, Annual review of immunology.

The T cell‐specific serine proteinase TSP‐1 is associated with cytoplasmic granules of cytolytic T lymphocytes

H. Simon, M. Kramer, H. Hengartner, 1987, European journal of immunology.

Postnatal disappearance of self-reactive (V beta 6+) cells from the thymus of Mlsa mice. Implications for T cell development and autoimmunity

R. Zinkernagel, H. Macdonald, T. Pedrazzini, 1989, The Journal of experimental medicine.

A comparison of efficacy and specificity of three NK depleting antibodies.

R. Zinkernagel, R. Nuesch, S. Ehl, 1996, Journal of immunological methods.

CD40-CD40 ligand interactions are critical in T-B cooperation but not for other anti-viral CD4+ T cell functions

R. Zinkernagel, A. Oxenius, M. Bachmann, 1996, The Journal of experimental medicine.

Protection against immunopathological consequences of a viral infection by activated but not resting cytotoxic T cells: T cell memory without "memory T cells"?

R. Zinkernagel, T. Kündig, M. Bachmann, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Vesicular stomatitis virus Indiana glycoprotein as a T-cell-dependent and -independent antigen

R. Zinkernagel, M. Bachmann, H. Hengartner, 1994, Journal of virology.

Vaccination for disease.

R. Zinkernagel, H. Hengartner, S. Oehen, 1991, Science.

Induction of diabetes is influenced by the infectious virus and local expression of MHC class I and tumor necrosis factor-alpha.

H. Pircher, R. Zinkernagel, P. Ohashi, 1993, Journal of immunology.

Localization of T helper cell epitopes in the vesicular stomatitis virus: the nucleoprotein is responsible for serotype cross-reactive T help.

R. Zinkernagel, U. Steinhoff, D. Bishop, 1994, Viral immunology.

Free recirculation of memory B cells versus antigen-dependent differentiation to antibody-forming cells.

R. Zinkernagel, T. Kündig, M. Bachmann, 1994, Journal of immunology.

Thymic selection of H-2-incompatible bone marrow cells in SCID mice. Differences in T help for induction of B cell IgG responses versus cytotoxic T cells

R. Zinkernagel, H. Hengartner, A. Althage, 1988, The Journal of experimental medicine.

On the role of antigen in maintaining cytotoxic T-cell memory.

H. Pircher, R. Zinkernagel, T. Kündig, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Protective antiviral cytotoxic T cell memory is most efficiently maintained by restimulation via dendritic cells.

R. Zinkernagel, B. Ludewig, R. Schwendener, 1999, Journal of immunology.

The role of antibody concentration and avidity in antiviral protection.

M Aguet, R M Zinkernagel, H Hengartner, 1997, Science.

Clonal deletion induced by either radioresistant thymic host cells or lymphohemopoietic donor cells at different stages of class I-restricted T cell ontogeny

H. Pircher, R. Zinkernagel, D. Speiser, 1992, The Journal of experimental medicine.

Clonal Deletion Induced by Either Radioresistant Thymic Host Cells or Lymphohemopoietic Donor Cells at Different Stages of Class I-restricted T Cell Ontogeny By Daniel E. Speiser, Hanspeter Pitcher, Pamela S. Ohashi,

H. Hengartner, Diego Kyburz, R. Zinkernagel, 1992 .

Intrathymic elimination of Mlsa-reactive (V beta 6+) cells during neonatal tolerance induction to Mlsa-encoded antigens

R. Zinkernagel, H. Macdonald, J. Louis, 1988, The Journal of experimental medicine.

Cd40-cd40 Ligand Interactions Are Critical in T-b Cooperation but Not for Other Anti-viral Cd4 § T Cell Functions

R. Zinkernagel, H. Hengartner, C. R. Maliszewski, 1996 .

Positive and negative selection of T cell receptor V beta domains controlled by distinct cell populations in the thymus

R. Zinkernagel, D. Speiser, H. Macdonald, 1989, The Journal of experimental medicine.

Clonal deletion of self-reactive T cells in irradiation bone marrow chimeras and neonatally tolerant mice. Evidence for intercellular transfer of Mlsa

R. Zinkernagel, D. Speiser, H. Macdonald, 1989, The Journal of experimental medicine.

Qualitative and quantitative requirements for CD4+ T cell-mediated antiviral protection.

H. Pircher, R. Zinkernagel, U. Hoffmann‐Rohrer, 1999, Journal of immunology.

Protection T Cell-Mediated Antiviral + for CD4 Qualitative and Quantitative Requirements

H. Pircher, R. Zinkernagel, U. Hoffmann‐Rohrer, 1999 .

Thymocytes can tolerize thymocytes by clonal deletion in vitro.

H. Pircher, B. Kyewski, H. Hengartner, 1992, International immunology.

Antiviral T cell competence and restriction specificity of mixed allogeneic (P1 + P2----P1) irradiation chimeras.

R. Zinkernagel, D. Sachs, M. Sykes, 1989, Cellular immunology.

Interferon gamma-producing gammadelta T cell-dependent antibody isotype switching in the absence of germinal center formation during virus infection.

R. Zinkernagel, H. Hengartner, K. Maloy, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Vaccination with a synthetic peptide modulates lymphocytic choriomeningitis virus-mediated immunopathology

R. Zinkernagel, M. Battegay, H. Hengartner, 1992, Journal of virology.

Mice expressing both B7-1 and viral glycoprotein on pancreatic beta cells along with glycoprotein-specific transgenic T cells develop diabetes due to a breakdown of T-lymphocyte unresponsiveness.

D. Harlan, H. Pircher, G. Freeman, 1994, Proceedings of the National Academy of Sciences of the United States of America.

Reactive oxygen species delay control of lymphocytic choriomeningitis virus

T. Mak, I. Harris, A. Pandyra, 2013, Cell Death and Differentiation.

Correlation of anti-viral B cell responses and splenic morphology with expression of B cell-specific molecules.

R. Zinkernagel, T. Fehr, R. Torres, 2000, International immunology.

The role of antibodies in natural and acquired resistance of mice to vesicular stomatitis virus.

R. Zinkernagel, H. Hengartner, A. Cerny, 1988, Experimental cell biology.

In vitro selection of lymphocytic choriomeningitis virus escape mutants by cytotoxic T lymphocytes.

R. Zinkernagel, D. Moskophidis, H. Hengartner, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Dendritic cells in autoimmune diseases.

R. Zinkernagel, T. Junt, B. Ludewig, 2001, Current opinion in immunology.

Different roles for cytotoxic T cells in the control of infections with cytopathic versus noncytopathic viruses.

H. Hengartner, D. Kägi, H. Hengartner, 1996, Current opinion in immunology.

Characterization of T-helper epitopes of the glycoprotein of vesicular stomatitis virus

R. Zinkernagel, L. Adorini, K. Wiesmüller, 1994, Journal of virology.

Peptide-induced T-cell tolerance to prevent autoimmune diabetes in a transgenic mouse model.

H. Pircher, R. Zinkernagel, P. Ohashi, 1994, Proceedings of the National Academy of Sciences of the United States of America.

Antiviral immune responses of mice lacking MHC class II or its associated invariant chain.

R. Zinkernagel, C. Benoist, M. Battegay, 1996, Cellular immunology.

The role of perforin‐expression by granular metrial gland cells in pregnancy

T. Stallmach, C. Müller, D. Kägi, 1995, European journal of immunology.