Penelope M. Drake

发表

IDPicker 2.0: Improved protein assembly with high discrimination peptide identification filtering.

Michael D. Litton, Scott M. Sobecki, B. Gibson, 2009, Journal of proteome research.

Lectin chromatography/mass spectrometry discovery workflow identifies putative biomarkers of aggressive breast cancers.

Michael P. Cusack, Dylan J. Sorensen, Jason M. Held, 2012, Journal of proteome research.

Reversal of gene dysregulation in cultured cytotrophoblasts reveals possible causes of preeclampsia.

S. Fisher, Yan Zhou, P. Drake, 2013, The Journal of clinical investigation.

CAT-02-106, a Site-Specifically Conjugated Anti-CD22 Antibody Bearing an MDR1-Resistant Maytansine Payload Yields Excellent Efficacy and Safety in Preclinical Models

Betty C. B. Huang, P. Drake, J. McFarland, 2017, Molecular Cancer Therapeutics.

Polysialic Acid, a Glycan with Highly Restricted Expression, Is Found on Human and Murine Leukocytes and Modulates Immune Responses1

Jay K. Nathan, C. Bertozzi, B. Weinhold, 2008, The Journal of Immunology.

Sweetening the pot: adding glycosylation to the biomarker discovery equation.

Susan J Fisher, Bradford W Gibson, N Leigh Anderson, 2010, Clinical chemistry.

Generating site-specifically modified proteins via a versatile and stable nucleophilic carbon ligation.

P. Drake, Romas Kudirka, J. McFarland, 2015, Chemistry & biology.

Aldehyde Tag Coupled with HIPS Chemistry Enables the Production of ADCs Conjugated Site-Specifically to Different Antibody Regions with Distinct in Vivo Efficacy and PK Outcomes

P. Drake, J. McFarland, David Rabuka, 2014, Bioconjugate chemistry.

Hydrazino-Pictet-Spengler ligation as a biocompatible method for the generation of stable protein conjugates.

P. Drake, David Rabuka, Aaron E. Albers, 2013, Bioconjugate chemistry.

Tandem-Cleavage Linkers Improve the In Vivo Stability and Tolerability of Antibody-Drug Conjugates.

P. Drake, Fangjiu Zhang, David Rabuka, 2021, Bioconjugate chemistry.

Human pregnancy: the role of chemokine networks at the fetal-maternal interface.

K. Red-Horse, S. Fisher, P. Drake, 2004, Expert reviews in molecular medicine.

A lectin affinity workflow targeting glycosite-specific, cancer-related carbohydrate structures in trypsin-digested human plasma.

Dylan J. Sorensen, F. Regnier, B. Gibson, 2011, Analytical biochemistry.

Human Placental Cytotrophoblasts Attract Monocytes and Cd56bright Natural Killer Cells via the Actions of Monocyte Inflammatory Protein 1α

S. Fisher, Yan Zhou, I. Charo, 2001, The Journal of experimental medicine.

Human pregnancy: the role of chemokine networks at the fetal–maternal interface

K. Red-Horse, S. Fisher, P. Drake, 2004, Expert Reviews in Molecular Medicine.

Antibody-Drug Conjugates: Can Coupling Cytotoxicity and Specificity Overcome Therapeutic Resistance?

P. Drake, David Rabuka, Penelope M. Drake, 2013 .

Maytansine-bearing antibody-drug conjugates induce in vitro hallmarks of immunogenic cell death selectively in antigen-positive target cells

P. Drake, I. Rupniewski, David Rabuka, 2019, Oncoimmunology.

Variation and quantification among a target set of phosphopeptides in human plasma by multiple reaction monitoring and SWATH‐MS2 data‐independent acquisition

Birgit Schilling, Michael P. Cusack, Jason M. Held, 2014, Electrophoresis.

Phosphoprotein Secretome of Tumor Cells as a Source of Candidates for Breast Cancer Biomarkers in Plasma

Michael P. Cusack, C. Benz, B. Gibson, 2014, Molecular & Cellular Proteomics.

A simple LC/MRM-MS-based method to quantify free linker-payload in antibody-drug conjugate preparations.

P. Drake, David Rabuka, Robyn M. Barfield, 2016, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

An emerging playbook for antibody-drug conjugates: lessons from the laboratory and clinic suggest a strategy for improving efficacy and safety.

P. Drake, David Rabuka, David Rabuka, 2015, Current opinion in chemical biology.

Exploring the effects of linker composition on site-specifically modified antibody-drug conjugates.

P. Drake, David Rabuka, Aaron E. Albers, 2014, European journal of medicinal chemistry.

A Case Study to Identify the Drug Conjugation Site of a Site-Specific Antibody-Drug-Conjugate Using Middle-Down Mass Spectrometry

S. Cianférani, A. Beck, R. Huguet, 2019, Journal of The American Society for Mass Spectrometry.

Urine, peritoneal fluid and omental fat proteomes of reproductive age women: Endometriosis-related changes and associations with endocrine disrupting chemicals.

L. Giudice, G. B. Buck Louis, S. Fisher, 2015, Journal of proteomics.

Chemokine Expression and Function at the Human Maternal–Fetal Interface

K. Red-Horse, S. Fisher, P. Drake, 2002, Reviews in Endocrine and Metabolic Disorders.

Chemokine ligand and receptor expression in the pregnant uterus: reciprocal patterns in complementary cell subsets suggest functional roles.

K. Red-Horse, S. Fisher, M. Gunn, 2001, The American journal of pathology.

Antibody-Drug Conjugates Targeting the Urokinase Receptor (uPAR) as a Possible Treatment of Aggressive Breast Cancer

Zev J. Gartner, L. V. van't Veer, Z. Gartner, 2019, Antibodies.

Insights from native mass spectrometry approaches for top- and middle- level characterization of site-specific antibody-drug conjugates

S. Cianférani, A. Beck, P. Drake, 2017, mAbs.

A Case Study to Identify the Drug Conjugation Site of a Site-Specific Antibody-Drug-Conjugate Using Middle-Down Mass Spectrometry

S. Cianférani, A. Beck, R. Huguet, 2019, Journal of The American Society for Mass Spectrometry.

Generating site-specifically modified proteins via a versatile and stable nucleophilic carbon ligation.

J. McFarland, David Rabuka, Aaron E. Albers, 2015, Chemistry & biology.

Recent Developments in ADC Technology: Preclinical Studies Signal Future Clinical Trends

P. Drake, David Rabuka, Penelope M. Drake, 2017, BioDrugs.

Polysialic acid governs T-cell development by regulating progenitor access to the thymus

Jay K. Nathan, C. Bertozzi, B. Weinhold, 2009, Proceedings of the National Academy of Sciences.

Antibody-drug conjugate library prepared by scanning insertion of the aldehyde tag into IgG1 constant regions

Betty C. B. Huang, W. Haskins, P. Drake, 2018, mAbs.

Stable, Versatile Conjugation Chemistries for Modifying Aldehyde‐Containing Biomolecules

P. Drake, David Rabuka, Aaron E. Albers, 2017 .

Generating aldehyde-tagged antibodies with high titers and high formylglycine yields by supplementing culture media with copper(II)

P. Drake, David Rabuka, G. Bleck, 2016, BMC Biotechnology.

Tandem-Cleavage Linkers Improve the In Vivo Stability and Tolerability of Antibody-Drug Conjugates

P. Drake, Fangjiu Zhang, David Rabuka, 2021, bioRxiv.

Stable, Site-Specific ADC Conjugation with SMARTag® Technology and Innovative Linker

Penelope M. Drake, 2022, ADC Review / Journal of Antibody-drug Conjugates.

Site-Specific Tandem Knoevenagel Condensation-Michael Addition To Generate Antibody-Drug Conjugates.

P. Drake, J. McFarland, Wes Zmolek, 2016, ACS medicinal chemistry letters.

Polysialic acid enhances the migration and invasion of human cytotrophoblasts.

I. Shih, S. Fisher, Gabriel A Goldfien, 2013, Glycobiology.

Reciprocal chemokine receptor and ligand expression in the human placenta: Implications for cytotrophoblast differentiation

K. Red-Horse, S. Fisher, P. Drake, 2004, Developmental dynamics : an official publication of the American Association of Anatomists.

Reconstitution of Formylglycine-generating Enzyme with Copper(II) for Aldehyde Tag Conversion

P. Drake, David Rabuka, Robyn M. Barfield, 2015, The Journal of Biological Chemistry.

A Novel HER2-targeted Antibody–drug Conjugate Offers the Possibility of Clinical Dosing at Trastuzumab-equivalent Exposure Levels

M. Pegram, P. Drake, Fangjiu Zhang, 2020, Molecular Cancer Therapeutics.