Mirjam Koker

发表

Identifying genotype-dependent efficacy of single and combined PI3K- and MAPK-pathway inhibition in cancer

William Pao, Thomas Zander, Martin Peifer, 2009, Proceedings of the National Academy of Sciences.

ALK Mutations Conferring Differential Resistance to Structurally Diverse ALK Inhibitors

William Pao, Michael Hölzel, Martin Peifer, 2011, Clinical Cancer Research.

HMGB2 Loss upon Senescence Entry Disrupts Genomic Organization and Induces CTCF Clustering across Cell Types.

J. Mallm, K. Rippe, D. Marenduzzo, 2018, Molecular cell.

Topological demarcation by HMGB2 is disrupted early upon senescence entry across cell types and induces CTCF clustering

Ivan G. Costa, J. Mallm, K. Rippe, 2017, bioRxiv.

Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer

K. Cibulskis, J. Shendure, G. Getz, 2012, Nature Genetics.

A framework for identification of actionable cancer genome dependencies in small cell lung cancer

Herbert Waldmann, Takashi Ninomiya, Martin Peifer, 2012, Proceedings of the National Academy of Sciences.

HMGB1 as a rheostat of chromatin topology and RNA homeostasis on the path to senescence

A. Beyer, E. Gusmão, M. Nikolic, 2019, bioRxiv.

Differential Protein Stability and ALK Inhibitor Sensitivity of EML4-ALK Fusion Variants

Roman K. Thomas, W. Pao, R. Küppers, 2012, Clinical Cancer Research.

Chemogenomic profiling provides insights into the limited activity of irreversible EGFR Inhibitors in tumor cells expressing the T790M EGFR resistance mutation.

Martin Peifer, Daniel Rauh, Lars Ruddigkeit, 2010, Cancer research.

Predicting drug susceptibility of non-small cell lung cancers based on genetic lesions.

Laura Tolosi, Michael Peyton, Thomas Zander, 2009, The Journal of clinical investigation.

Cancer Therapy : Preclinical See commentary by Crystal and Shaw , p . 4479 Differential Protein Stability and ALK Inhibitor Sensitivity of EML 4-ALK Fusion Variants

Roman K. Thomas, W. Pao, M. Peifer, 2012 .

Frequent and Focal FGFR1 Amplification Associates with Therapeutically Tractable FGFR1 Dependency in Squamous Cell Lung Cancer

I. Petersen, R. Beroukhim, H. Groen, 2010, Science Translational Medicine.

PTEN loss contributes to erlotinib resistance in EGFR-mutant lung cancer by activation of Akt and EGFR.

M. Meyerson, C. Mermel, B. Weir, 2009, Cancer research.

CD74-NRG1 fusions in lung adenocarcinoma.

I. Petersen, S. Haas, M. Vingron, 2014, Cancer discovery.

LIN28B enhanced tumorigenesis in an autochthonous KRASG12V-driven lung carcinoma mouse model

M. Odenthal, F. Dietlein, R. Büttner, 2018, Oncogene.

Mutations in the DDR2 kinase gene identify a novel therapeutic target in squamous cell lung cancer.

M. Meyerson, I. Petersen, R. Onofrio, 2011, Cancer discovery.

Interaction of the Cytosolic Domains of sorLA/LR11 with the Amyloid Precursor Protein (APP) and β-Secretase β-Site APP-Cleaving Enzyme

B. Hyman, M. Irizarry, C. V. von Arnim, 2006, The Journal of Neuroscience.

Analysis of Compound Synergy in High-Throughput Cellular Screens by Population-Based Lifetime Modeling

Martin Peifer, Daniel Rauh, Jörg Rahnenführer, 2010, PloS one.

Comparative Analysis of the Human and Chicken Prion Protein Copper Binding Regions at pH 6.5*

M. Perbandt, C. Betzel, H. Kalbacher, 2005, Journal of Biological Chemistry.

Identification of novel fusion genes in lung cancer using breakpoint assembly of transcriptome sequencing data

I. Petersen, S. Haas, M. Vingron, 2015, Genome Biology.

Formation of Toxic Oligomeric α-Synuclein Species in Living Cells

Bradley T. Hyman, Preeti Putcha, B. Hyman, 2008, PloS one.

Early Detection of Erlotinib Treatment Response in NSCLC by 3′-Deoxy-3′-[18F]-Fluoro-L-Thymidine ([18F]FLT) Positron Emission Tomography (PET)

Roman K. Thomas, T. Zander, G. Shapiro, 2008, PloS one.

Notch1 Deficiency Induces Tumor Cell Accumulation Inside the Bronchiolar Lumen and Increases TAZ Expression in an Autochthonous Kras LSL-G12V Driven Lung Cancer Mouse Model

M. Odenthal, R. Büttner, F. Radtke, 2021, Pathology & Oncology Research.

Synergistic anti-angiogenic treatment effects by dual FGFR1 and VEGFR1 inhibition in FGFR1-amplified breast cancer

M. Hallek, F. Dietlein, R. Büttner, 2018, Oncogene.

Tumor VEGF:VEGFR2 autocrine feed-forward loop triggers angiogenesis in lung cancer

Martin Peifer, Daniel Rauh, Gerhard Christofori, 2013 .

Tumor VEGF:VEGFR2 autocrine feed-forward loop triggers angiogenesis in lung cancer.

Roman K. Thomas, G. Christofori, M. Peifer, 2013, The Journal of clinical investigation.

Mutations in the DDR 2 Kinase Gene identify a Novel therapeutic target in squamous cell lung cancer

M. Meyerson, I. Petersen, R. Onofrio, 2011 .

in squamous cell lung cancer

M. Meyerson, I. Petersen, R. Onofrio, 2011 .

The LDL receptor-related protein can form homo-dimers in neuronal cells

B. Hyman, K. Adams, D. Strickland, 2008, Neuroscience Letters.

Inhibition of Tumor VEGFR2 Induces Serine 897 EphA2-Dependent Tumor Cell Invasion and Metastasis in NSCLC.

M. Hallek, F. Dietlein, R. Büttner, 2020, Cell reports.

GGA1 Acts as a Spatial Switch Altering Amyloid Precursor Protein Trafficking and Processing

B. Hyman, M. Irizarry, C. V. von Arnim, 2006, The Journal of Neuroscience.

Correction: Formation of Toxic Oligomeric α-Synuclein Species in Living Cells

Bradley T. Hyman, Preeti Putcha, B. Hyman, 2008, PLoS ONE.

HMGB2 Loss upon Senescence Entry Disrupts Genomic Organization and Induces CTCF Clustering across Cell Types.

K. Rippe, D. Marenduzzo, C. Brackley, 2018, Molecular cell.

Frequent and Focal FGFR1 Amplification Associates with Therapeutically Tractable FGFR1 Dependency in Squamous Cell Lung Cancer

I. Petersen, R. Beroukhim, H. Groen, 2010, Science Translational Medicine.

Interaction of the apolipoprotein E receptors low density lipoprotein receptor-related protein and sorLA/LR11

B. Hyman, K. Adams, D. Strickland, 2009, Neuroscience.

Synthetic human prion protein octapeptide repeat binds to the proteinase K active site.

M. Perbandt, C. Betzel, L. Redecke, 2004, Biochemical and biophysical research communications.

Identification of novel fusion genes in lung cancer using breakpoint assembly of transcriptome sequencing data

I. Petersen, S. Haas, M. Vingron, 2015, Genome Biology.