Christian Wagner

发表

Application of an automated small-scale in vitro transfer model to predict in vivo precipitation inhibition.

W. Weitschies, M. Koziolek, C. Wagner, 2019, International journal of pharmaceutics.

Application of Physiologically Based Pharmacokinetic (PBPK) Modeling to Support Dose Selection: Report of an FDA Public Workshop on PBPK

Shiew-Mei Huang, S‐M Huang, P. Zhao, 2015, CPT: pharmacometrics & systems pharmacology.

Use of Physiologically Based Pharmacokinetic (PBPK) Modeling for Predicting Drug-Food Interactions: an Industry Perspective

S. Basu, Yuan Chen, Cordula Stillhart, 2020, The AAPS Journal.

Predictive Performance of Physiologically Based Pharmacokinetic Models for the Effect of Food on Oral Drug Absorption: Current Status

Ping Zhao, Christian Wagner, P. Zhao, 2017, CPT: pharmacometrics & systems pharmacology.

Prediction of in‐vivo pharmacokinetic profile for immediate and modified release oral dosage forms of furosemide using an in‐vitro–in‐silico–in‐vivo approach

Arzu Selen, Christian Wagner, Jennifer Dressman, 2015, The Journal of pharmacy and pharmacology.

Streamlining Food Effect Assessment — Are Repeated Food Effect Studies Needed? An IQ Analysis

T. Heimbach, S. Vaidhyanathan, F. Kesisoglou, 2023, The AAPS Journal.

Best Practices in the Development and Validation of Physiologically Based Biopharmaceutics Modeling. A Workshop Summary Report.

Talia Flanagan, Amitava Mitra, Sandra Suarez-Sharp, 2020, Journal of pharmaceutical sciences.

Predicting the Effect of CYP3A Inducers on the Pharmacokinetics of Substrate Drugs Using Physiologically Based Pharmacokinetic (PBPK) Modeling: An Analysis of PBPK Submissions to the US FDA

Vikram Sinha, Ping Zhao, Christian Wagner, 2016, Clinical Pharmacokinetics.

Predicting the Effect of Cytochrome P450 Inhibitors on Substrate Drugs: Analysis of Physiologically Based Pharmacokinetic Modeling Submissions to the US Food and Drug Administration

Lei Zhang, Vikram Sinha, Ping Zhao, 2014, Clinical Pharmacokinetics.

Improved prediction of in vivo supersaturation and precipitation of poorly soluble weakly basic drugs using a biorelevant bicarbonate buffer in a GI transfer model.

W. Weitschies, M. Koziolek, C. Wagner, 2019, Molecular pharmaceutics.

Automated small-scale in vitro transfer model as screening tool for the prediction of in vivo-dissolution and precipitation of poorly solubles.

W. Weitschies, M. Koziolek, C. Wagner, 2019, International journal of pharmaceutics.

In‐line derivative spectroscopy as a promising application to a small‐scale in vitro transfer model in biorelevant supersaturation and precipitation testing

W. Weitschies, C. Wagner, Christian Weber, 2018, The Journal of pharmacy and pharmacology.

The effect of buffer species on biorelevant dissolution and precipitation assays - Comparison of phosphate and bicarbonate buffer.

A. Lehmann, W. Weitschies, C. Wagner, 2021, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Use of Physiologically Based Pharmacokinetic Modeling for Predicting Drug–Food Interactions: Recommendations for Improving Predictive Performance of Low Confidence Food Effect Models

F. Kesisoglou, N. Parrott, X. Pepin, 2021, The AAPS Journal.

PBPK models for the prediction of in vivo performance of oral dosage forms.

Martin Bergstrand, Xavier Pepin, Erik Sjögren, 2014, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Utilizing in vitro and PBPK tools to link ADME characteristics to plasma profiles: case example nifedipine immediate release formulation.

Stefan Willmann, Arzu Selen, Christian Wagner, 2013, Journal of pharmaceutical sciences.

Predicting the oral absorption of a poorly soluble, poorly permeable weak base using biorelevant dissolution and transfer model tests coupled with a physiologically based pharmacokinetic model.

Filippos Kesisoglou, Christos Reppas, Christian Wagner, 2012, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Biorelevant in vitro dissolution testing of products containing micronized or nanosized fenofibrate with a view to predicting plasma profiles.

Christos Reppas, Christian Wagner, Jennifer B Dressman, 2011, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Increasing the robustness of biopharmaceutical precipitation assays - Part I: Derivative UV spectrophotometric method development for in-line measurements.

A. Lehmann, Katharina Krollik, Holger Kubas, 2021, Journal of pharmaceutical sciences.

Increasing the robustness of biopharmaceutical precipitation assays - Part II: Recommendations on the use of FaSSIF.

A. Lehmann, W. Weitschies, C. Wagner, 2021, Journal of pharmaceutical sciences.

Impact of amorphization and GI physiology on supersaturation and precipitation of poorly soluble weakly basic drugs using a small-scale in vitro transfer model.

K. Mäder, C. Wagner, M. Harms, 2019, International journal of pharmaceutics.

Screening for differences in early exposure in the fasted state with in vitro methodologies can be challenging: Experience with the BioGIT system.

C. Reppas, M. Vertzoni, Jan Bevernage, 2023, Journal of pharmaceutical sciences.

Usefulness of the BioGIT system in screening for differences in early exposure in the fasted state on an a priori basis.

C. Reppas, M. Vertzoni, Jan Bevernage, 2023, International journal of pharmaceutics.