Joshua T. Dearborn

发表

Recombinant NAGLU-IGF2 prevents physical and neurological disease and improves survival in Sanfilippo B syndrome

Jodi D. Smith, T. Chou, J. Cooper, 2021, bioRxiv.

Cross-species efficacy of enzyme replacement therapy for CLN1 disease in mice and sheep

S. Ekins, C. Whitelaw, S. Lillico, 2022, The Journal of clinical investigation.

Effects of chronic cannabidiol in a mouse model of naturally occurring neuroinflammation, neurodegeneration, and spontaneous seizures

J. Cooper, M. Sands, T. Wishart, 2022, Scientific Reports.

Synergistic effects of treating the spinal cord and brain in CLN1 disease

R. Schmidt, J. Cooper, M. Sands, 2017, Proceedings of the National Academy of Sciences.

Histochemical localization of palmitoyl protein thioesterase-1 activity.

M. Sands, S. Hofmann, S. Ramachandran, 2016, Molecular genetics and metabolism.

Comprehensive functional characterization of murine infantile Batten disease including Parkinson-like behavior and dopaminergic markers

D. Wozniak, M. Sands, K. O’Malley, 2015, Scientific Reports.

An Anti-Neuroinflammatory That Targets Dysregulated Glia Enhances the Efficacy of CNS-Directed Gene Therapy in Murine Infantile Neuronal Ceroid Lipofuscinosis

J. Cooper, M. Sands, S. Fowler, 2014, The Journal of Neuroscience.

Widespread Expression of a Membrane-Tethered Version of the Soluble Lysosomal Enzyme Palmitoyl Protein Thioesterase-1.

M. Sands, J. Dearborn, S. Macauley, 2017, JIMD reports.

Gene therapy ameliorates spontaneous seizures associated with cortical neuron loss in a Cln2R207X mouse model

O. Danos, J. Cooper, M. Sands, 2023, The Journal of clinical investigation.

Spinal manifestations of CLN1 disease start during the early postnatal period

J. Cooper, M. Sands, J. Dearborn, 2020, Neuropathology and applied neurobiology.

Hormones in the mentally disturbed brain: steroids and peptides in the development and treatment of psychopathology.

S. Maloney, J. Dearborn, G. Taylor, 2009, Central nervous system agents in medicinal chemistry.

Motivational Disturbances and Effects of L-dopa Administration in Neurofibromatosis-1 Model Mice

D. Gutmann, Y. Izumi, C. Zorumski, 2013, PloS one.

Bone Marrow Transplantation Alters the Tremor Phenotype in the Murine Model of Globoid-Cell Leukodystrophy

N. Farber, D. Wozniak, M. Sands, 2012, Journal of clinical medicine.

Circadian clock proteins regulate neuronal redox homeostasis and neurodegeneration.

D. Holtzman, J. Hogenesch, G. FitzGerald, 2013, The Journal of clinical investigation.

Novel Behavioral Markers in the Ppt1-/- Mouse Model of Infantile Neuronal Ceroid Lipofuscinosis

Joshua T. Dearborn, 2013 .

Geminin deficiency enhances survival in a murine medulloblastoma model by inducing apoptosis of preneoplastic granule neuron precursors

D. Wozniak, K. Kroll, S. Sankar, 2017, Genes & cancer.

Genetic ablation of acid ceramidase in Krabbe disease confirms the psychosine hypothesis and identifies a new therapeutic target

J. Medin, D. Wozniak, Yedda Li, 2019, Proceedings of the National Academy of Sciences.

Anti-ApoE Antibody Given after Plaque Onset Decreases Aβ Accumulation and Improves Brain Function in a Mouse Model of Aβ Amyloidosis

Hong Jiang, Rebecca Betensky, David M Holtzman, 2014, The Journal of Neuroscience.

Impact of hepatitis C coinfection on cognitive outcomes in HIV-infected individuals

R. Paul, S. Letendre, J. Dearborn, 2007 .

Core features of frontotemporal dementia recapitulated in progranulin knockout mice

N. Cairns, D. Wozniak, N. Ghoshal, 2012, Neurobiology of Disease.

Expression of Nampt in Hippocampal and Cortical Excitatory Neurons Is Critical for Cognitive Function

Y. Izumi, C. Zorumski, D. Wozniak, 2014, The Journal of Neuroscience.

A MYT1L syndrome mouse model recapitulates patient phenotypes and reveals altered brain development due to disrupted neuronal maturation

Keith B. Hengen, Harrison W. Gabel, K. B. Hengen, 2020, Neuron.

Adjunctive Therapy for Long-Term Support of Cognitive Impairment

R. Paul, S. Maloney, Elizabeth M. Lane, 2009 .

Loss of RBPj in Postnatal Excitatory Neurons Does Not Cause Neurodegeneration or Memory Impairments in Aged Mice

Raphael Kopan, D. Wozniak, C. Sato, 2012, PloS one.

Anti-ApoE Antibody Given after Plaque Onset Decreases Aβ Accumulation and Improves Brain Function in a Mouse Model of Aβ Amyloidosis

D. Holtzman, B. Hyman, J. Culver, 2014, The Journal of Neuroscience.

Circadian clock proteins regulate neuronal redox homeostasis and neurodegeneration.

D. Holtzman, J. Hogenesch, G. FitzGerald, 2013, The Journal of clinical investigation.

Synergistic effects of treating the spinal cord and brain in CLN1 disease

R. Schmidt, J. Cooper, M. Sands, 2017, Proceedings of the National Academy of Sciences.

Cell-autonomous expression of the acid hydrolase galactocerebrosidase

J. Milbrandt, M. Sands, B. Benitez, 2020, Proceedings of the National Academy of Sciences.

Cortical interneuron loss and seizure generation as novel clinically relevant disease phenotypes in Cln2R207X mice

J. Cooper, M. Sands, N. Rensing, 2022, bioRxiv.

Histochemical localization of palmitoyl protein thioesterase-1 activity.

M. Sands, S. Hofmann, S. Ramachandran, 2016, Molecular genetics and metabolism.