M. E. Lie

Exploring the molecular determinants for subtype-selectivity of 2-amino-1,4,5,6-tetrahydropyrimidine-5-carboxylic acid analogs as betaine/GABA transporter 1 (BGT1) substrate-inhibitors

G. Ecker, P. Wellendorph, B. Frølund, 2020, Scientific Reports.

Glial GABA Transporters as Modulators of Inhibitory Signalling in Epilepsy and Stroke.

A. Schousboe, A. Clarkson, P. Wellendorph, 2017, Advances in neurobiology.

Molecular Determinants and Pharmacological Analysis for a Class of Competitive Non-transported Bicyclic Inhibitors of the Betaine/GABA Transporter BGT1

S. Shuto, G. Ecker, P. Wellendorph, 2021, Frontiers in Chemistry.

Pharmacological Characterization of a Betaine/GABA Transporter 1 (BGT1) Inhibitor Displaying an Unusual Biphasic Inhibition Profile and Anti-seizure Effects

G. Ecker, A. Schousboe, H. White, 2020, Neurochemical Research.

GAT3 selective substrate l-isoserine upregulates GAT3 expression and increases functional recovery after a focal ischemic stroke in mice

N. O. Dalby, A. Clarkson, P. Wellendorph, 2017, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Identification of the First Highly Subtype-Selective Inhibitor of Human GABA Transporter GAT3.

G. Ecker, P. Wellendorph, B. Frølund, 2015, ACS chemical neuroscience.

Inhibition of GABA transporters fails to afford significant protection following focal cerebral ischemia

A. Clarkson, P. Wellendorph, R. Clausen, 2018, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Development of Non-GAT1-Selective Inhibitors: Challenges and Achievements.

G. Ecker, B. Frølund, R. Clausen, 2017, Advances in neurobiology.

Pharmacological Identification of a Guanidine-Containing β-Alanine Analogue with Low Micromolar Potency and Selectivity for the Betaine/GABA Transporter 1 (BGT1)

P. Wellendorph, B. Frølund, R. Clausen, 2014, Neurochemical Research.

Structural and stereochemical determinants for hGAT3 inhibition: development of novel conformationally constrained and substituted analogs of (S)-isoserine

P. Wellendorph, B. Frølund, F. Bavo, 2023, Medicinal Chemistry Research.