Chengwei He

发表

Qualitative and quantitative analysis of the saponins in Panax notoginseng leaves using ultra-performance liquid chromatography coupled with time-of-flight tandem mass spectrometry and high performance liquid chromatography coupled with UV detector

F. Liu, Yuan-Jia Hu, Peng Li, 2017, Journal of ginseng research.

Improved spatial learning performance of fat-1 mice is associated with enhanced neurogenesis and neuritogenesis by docosahexaenoic acid

Libin Cui, Chengwei He, J. Kang, 2009, Proceedings of the National Academy of Sciences.

Concise Review: Regulation of Stem Cell Proliferation and Differentiation by Essential Fatty Acids and Their Metabolites

J. Wan, Chengwei He, J. Kang, 2014, Stem cells.

Using flavonoids as a therapeutic intervention against rheumatoid arthritis: the known and unknown

Chengwei He, Zhimin Miao, Chengwei He, 2021, Pharmacological Research - Modern Chinese Medicine.

The role of Raptor in lymphocytes differentiation and function

M. Kubo, L. James, Lu Yang, 2023, Frontiers in Immunology.

Recent insights into the biological activities and drug delivery systems of tanshinones

Meiwan Chen, Chengwei He, Yuee Cai, 2016, International journal of nanomedicine.

Supporting Online Material Materials and Methods Figs. S1 to S13 Tables S1 to S3 References Label-free Biomedical Imaging with High Sensitivity by Stimulated Raman Scattering Microscopy

Mortazavi, D. Higgins, X. Xie, 2022 .

Vitamin E succinate-conjugated F68 micelles for mitoxantrone delivery in enhancing anticancer activity

Hui Li, Jian-Bo Wan, Chengwei He, 2016, International journal of nanomedicine.

Recent Advances in Anticancer Activities and Drug Delivery Systems of Tannins

Meiwan Chen, Chengwei He, N. Chen, 2017, Medicinal research reviews.

The structure-mechanism relationship and mode of actions of antimicrobial peptides: A review

Chengwei He, Haixia Chen, Yajie Wang, 2021 .

Naturally occurring coumestans from plants, their biological activities and therapeutic effects on human diseases.

Chengwei He, Yanfang Li, Yan-bei Tu, 2021, Pharmacological research.

Drug resistance of targeted therapy for advanced non-small cell lung cancer harbored EGFR mutation: from mechanism analysis to clinical strategy

Chengwei He, Yuxin Zhao, Haiyong Wang, 2021, Journal of Cancer Research and Clinical Oncology.

Protection against Oxygen-Glucose Deprivation/Reperfusion Injury in Cortical Neurons by Combining Omega-3 Polyunsaturated Acid with Lyciumbarbarum Polysaccharide

Zhijian Huang, Jian-Bo Wan, Chengwei He, 2016, Nutrients.

Inhibiting Delta-6 Desaturase Activity Suppresses Tumor Growth in Mice

Chengwei He, J. Kang, Keyuan Zhou, 2012, PloS one.

Endoplasmic Reticulum Stress of Gut Enterocyte and Intestinal Diseases

Chengwei He, H. Shang, Chen Liang, 2022, Frontiers in Molecular Biosciences.

Prospects of Poria cocos polysaccharides: Isolation process, structural features and bioactivities

Peng Li, Meiwan Chen, Chengwei He, 2016 .

Delta‐6‐desaturase activity and arachidonic acid synthesis are increased in human breast cancer tissue

Anthony J. Guidi, A. Guidi, Chengwei He, 2013, Cancer science.

Hormetic Effect of Berberine Attenuates the Anticancer Activity of Chemotherapeutic Agents

J. Wan, Jiaolin Bao, Borong Huang, 2015, PloS one.

Fast identification of anticancer constituents in Forsythiae Fructus based on metabolomics approaches

Peng Li, J. Wan, Jiaolin Bao, 2018, Journal of pharmaceutical and biomedical analysis.

Differences in Chemical Component and Anticancer Activity of Green and Ripe Forsythiae Fructus.

Peng Li, J. Wan, Jiaolin Bao, 2017, The American journal of Chinese medicine.

Endogenous Docosahexaenoic Acid (DHA) Prevents Aβ1–42 Oligomer-Induced Neuronal Injury

Peng Li, T. Yuan, J. Wan, 2016, Molecular Neurobiology.

Co-delivery of paclitaxel and tetrandrine via iRGD peptide conjugated lipid-polymer hybrid nanoparticles overcome multidrug resistance in cancer cells

Yitao Wang, Meiwan Chen, Chengwei He, 2017, Scientific Reports.

Anticancer Properties and Pharmaceutical Applications of Plumbagin: A Review.

Chengwei He, Mei-wan Chen, Yuee Cai, 2017, The American journal of Chinese medicine.

Anti-angiogenesis and anti-metastasis effects of Polyphyllin VII on Hepatocellular carcinoma cells in vitro and in vivo

Chao Zhang, Chengwei He, Liwen Han, 2021, Chinese Medicine.

Protective Effects of Otophylloside N on Pentylenetetrazol-Induced Neuronal Injury In vitro and In vivo

Peng Li, Huanxing Su, Chengwei He, 2016, Front. Pharmacol..

Synergistic chemopreventive effects of curcumin and berberine on human breast cancer cells through induction of apoptosis and autophagic cell death

Peng Li, J. Wan, Jiaolin Bao, 2016, Scientific Reports.

Anti-inflammatory effects of Glycine tabacina extract in LPS-stimulated macrophages and collagen-induced arthritis mice

J. Wan, Chengwei He, Kai Wang, 2019, Journal of Functional Foods.

Glycine tabacina ethanol extract ameliorates collagen-induced arthritis in rats via inhibiting pro-inflammatory cytokines and oxidation.

J. Wan, Chengwei He, Jianping Han, 2019, Journal of ethnopharmacology.

Polyphyllin VII induces apoptosis in HepG2 cells through ROS-mediated mitochondrial dysfunction and MAPK pathways

Peng Li, J. Wan, Jiaolin Bao, 2015, BMC Complementary and Alternative Medicine.

Fish oil alleviates LPS-induced inflammation and depressive-like behavior in mice via restoration of metabolic impairments

Peng Li, J. Wan, Huanxing Su, 2020, Brain, Behavior, and Immunity.

Rationale for the Use of Natural Anti-Inflammatory Agents in Cancer Chemotherapy

J. Wan, Chengwei He, Jing Liu, 2010 .

Cucurbitacins: A Systematic Review of the Phytochemistry and Anticancer Activity.

Yitao Wang, Peng Li, Meiwan Chen, 2015, The American journal of Chinese medicine.

Glycyrrhetinic Acid Mediated Drug Delivery Carriers for Hepatocellular Carcinoma Therapy.

Meiwan Chen, Chengwei He, Yuee Cai, 2016, Molecular pharmaceutics.

Enriched Endogenous Omega-3 Fatty Acids in Mice Ameliorate Parenchymal Cell Death After Traumatic Brain Injury

Peng Li, J. Wan, Huanxing Su, 2017, Molecular Neurobiology.

Label-Free Biomedical Imaging with High Sensitivity by Stimulated Raman Scattering Microscopy

Xiaohui Xie, Wei Min, C. Freudiger, 2008 .

Neuroprotective effects of ginsenosides on neural progenitor cells against oxidative injury

Peng Li, J. Wan, Huanxing Su, 2016, Molecular medicine reports.

Effect of Fe (III), Zn (II), and Cr (III) complexation on the physicochemical properties and bioactivities of corn silk polysaccharide.

M. Zhang, Haixia Chen, Nannan Li, 2021, International journal of biological macromolecules.

The structural characteristic of acidic-hydrolyzed corn silk polysaccharides and its protection on the H2O2-injured intestinal epithelial cells.

M. Zhang, Chengwei He, Haixia Chen, 2021, Food chemistry.

Dietary α-linolenic acid-rich flaxseed oil prevents against alcoholic hepatic steatosis via ameliorating lipid homeostasis at adipose tissue-liver axis in mice

M. Wang, Yuan-Jia Hu, Peng Li, 2016, Scientific Reports.

Quantitative profiling of eicosanoids derived from n-6 and n-3 polyunsaturated fatty acids by twin derivatization strategy combined with LC-MS/MS in patients with type 2 diabetes mellitus.

J. Wan, Chengwei He, Fang-bo Xia, 2020, Analytica chimica acta.

STING as an emerging therapeutic target for drug discovery: Perspectives from the global patent landscape

Chengwei He, Yuanjia Hu, Xiangjun Kong, 2022, Journal of advanced research.

Targeting Autophagy Using Saponins as a Therapeutic and Preventive Strategy against Human Diseases.

Chengwei He, Bing Han, Chengwei He, 2021, Pharmacological research.

Anticancer activities and mechanisms of heat-clearing and detoxicating traditional Chinese herbal medicine

Chengwei He, Yulin Zhang, Chengwei He, 2017, Chinese Medicine.

Development of nanoscale drug delivery systems of dihydroartemisinin for cancer therapy: A review

Meiwan Chen, Chengwei He, Shanshan Chen, 2022, Asian journal of pharmaceutical sciences.

In Vitro and In Vivo Anti-Inflammatory Effects of Polyphyllin VII through Downregulating MAPK and NF-κB Pathways

Chao Zhang, Chengwei He, Kechun Liu, 2019, Molecules.

Low Doses of Camptothecin Induced Hormetic and Neuroprotective Effects in PC12 Cells

J. Wan, Jiaolin Bao, Borong Huang, 2015, Dose-response : a publication of International Hormesis Society.

Triphenylphosphonium-modified poly(ethylene glycol)-poly(ε-caprolactone) micelles for mitochondria- targeted gambogic acid delivery.

Meiwan Chen, Chengwei He, Shengpeng Wang, 2017, International journal of pharmaceutics.

Coptis extracts enhance the anticancer effect of estrogen receptor antagonists on human breast cancer cells.

Chengwei He, J. Kang, Keyuan Zhou, 2009, Biochemical and biophysical research communications.

Anti-melanoma activity of Forsythiae Fructus aqueous extract in mice involves regulation of glycerophospholipid metabolisms by UPLC/Q-TOF MS-based metabolomics study

Peng Li, J. Wan, Jiaolin Bao, 2016, Scientific Reports.

UHPLC/Q-TOFMS-based metabolomics for the characterization of cold and hot properties of Chinese materia medica.

M. Wang, Yuan-Jia Hu, Peng Li, 2016, Journal of ethnopharmacology.

Anti-inflammatory activity of flavonols via inhibiting MAPK and NF-κB signaling pathways in RAW264.7 macrophages

J. Simal-Gándara, Chengwei He, Lingchao Miao, 2022, Current research in food science.

A Simple Method for Peak Alignment Using Relative Retention Time Related to an Inherent Peak in Liquid Chromatography-Mass Spectrometry-Based Metabolomics.

Peng Li, Li Ma, Yang Wang, 2018, Journal of chromatographic science.

Glytabastan B, a coumestan isolated from Glycine tabacina, alleviated synovial inflammation, osteoclastogenesis and collagen-induced arthritis through inhibiting MAPK and PI3K/AKT pathways.

Meiwan Chen, Chengwei He, Haixia Chen, 2022, Biochemical pharmacology.

Isolation and Identification of Antiarthritic Constituents from Glycine tabacina and Network Pharmacology-Based Prediction of Their Protective Mechanisms against Rheumatoid Arthritis.

Chengwei He, Qingwen Zhang, Bing Han, 2020, Journal of agricultural and food chemistry.

Dolichosin A, a coumestan isolated from Glycine tabacina, inhibits IL-1β-induced inflammation in SW982 human synovial cells and suppresses RANKL-induced osteoclastogenesis: From network pharmacology to experimental pharmacology.

Chengwei He, Yuanjia Hu, Hang Ding, 2020, Journal of ethnopharmacology.

Purification, structural characterization and anticancer activity of the novel polysaccharides from Rhynchosia minima root.

J. Wan, Jiaolin Bao, Chao Zhang, 2015, Carbohydrate polymers.

Cucurbitacin B inhibits proliferation, induces G2/M cycle arrest and autophagy without affecting apoptosis but enhances MTT reduction in PC12 cells

Jin-jian Lu, Xiuping Chen, Jiaolin Bao, 2015 .

Ginsenoside Rb1 attenuates angiotensin II-induced abdominal aortic aneurysm through inactivation of the JNK and p38 signaling pathways.

Peng Li, J. Wan, Huanxing Su, 2015, Vascular pharmacology.

Metabolomics study of the anti-inflammatory effects of endogenous omega-3 polyunsaturated fatty acids

Peng Li, J. Wan, Huanxing Su, 2019, RSC advances.

Ginsenoside Rg1, a potential JNK inhibitor, protects against ischemia/reperfusion-induced liver damage

Peng Li, J. Wan, Huanxing Su, 2015 .

Regulator of G protein signaling 5 protects against cardiac hypertrophy and fibrosis during biomechanical stress of pressure overload

S. Heximer, Q. Tang, Chengwei He, 2010, Proceedings of the National Academy of Sciences.

Berberine protects against 6-OHDA-induced neurotoxicity in PC12 cells and zebrafish through hormetic mechanisms involving PI3K/AKT/Bcl-2 and Nrf2/HO-1 pathways

Peng Li, J. Wan, Jiaolin Bao, 2016, Redox biology.

Recent advances in the biosynthesis, structure–activity relationships, formulations, pharmacology, and clinical trials of fisetin

M. Farag, Meiwan Chen, Chengwei He, 2022, eFood.

Omega-3 Polyunsaturated Fatty Acids Protect Neural Progenitor Cells against Oxidative Injury

J. Wan, Huanxing Su, Chengwei He, 2014, Marine drugs.

Preventive effect of α-linolenic acid-rich flaxseed oil against ethanol-induced liver injury is associated with ameliorating gut-derived endotoxin-mediated inflammation in mice

Peng Li, J. Wan, Meiwan Chen, 2016 .

Enriched endogenous omega-3 fatty acids in mice protect against global ischemia injury

J. Wan, Huanxing Su, Chengwei He, 2014, Journal of Lipid Research.

Quantification of phospholipid fatty acids by chemical isotope labeling coupled with atmospheric pressure gas chromatography quadrupole- time-of-flight mass spectrometry (APGC/Q-TOF MS).

Yuan-Jia Hu, J. Wan, Huanxing Su, 2019, Analytica chimica acta.

Underlying beneficial effects of Rhubarb on constipation-induced inflammation, disorder of gut microbiome and metabolism

Chengwei He, H. Shang, Yixuan Du, 2022, bioRxiv.

Saponins isolated from the leaves of Panax notoginseng protect against alcoholic liver injury via inhibiting ethanol-induced oxidative stress and gut-derived endotoxin-mediated inflammation

Yuan-Jia Hu, Peng Li, J. Wan, 2015 .

Synergistic anti-breast cancer effect of pulsatilla saponin D and camptothecin through interrupting autophagic-lysosomal function and promoting p62-mediated ubiquitinated protein aggregation.

J. Wan, Meiwan Chen, Chengwei He, 2020, Carcinogenesis.

Enriched Endogenous Omega-3 Polyunsaturated Fatty Acids Protect Cortical Neurons from Experimental Ischemic Injury

Ti-Fei Yuan, Peng Li, Jian-Bo Wan, 2016, Molecular Neurobiology.

An improved pseudotargeted metabolomics approach using multiple ion monitoring with time-staggered ion lists based on ultra-high performance liquid chromatography/quadrupole time-of-flight mass spectrometry.

Fang Liu, Yang Wang, Jian-Bo Wan, 2016, Analytica chimica acta.

Endogenous Docosahexaenoic Acid (DHA) Prevents Aβ1–42 Oligomer-Induced Neuronal Injury

Ti-Fei Yuan, Jian-Bo Wan, Chengwei He, 2015, Molecular Neurobiology.

Polysaccharide PRM3 from Rhynchosia minima root enhances immune function through TLR4-NF-κB pathway.

Peng Li, J. Wan, Chao Zhang, 2018, Biochimica et biophysica acta. General subjects.

Niosome Encapsulation of Curcumin

Peng Li, J. Wan, Meiwan Chen, 2016 .

Pluronic F68-Linoleic Acid Nano-spheres Mediated Delivery of Gambogic Acid for Cancer Therapy

Meiwan Chen, Chengwei He, Shengpeng Wang, 2016, AAPS PharmSciTech.

Ultrasonic extraction, antioxidant and anticancer activities of novel polysaccharides from Chuanxiong rhizome.

Peng Li, Meiwan Chen, Chengwei He, 2016, International journal of biological macromolecules.

Protective effect of panax notoginseng saponins on acute ethanol-induced liver injury is associated with ameliorating hepatic lipid accumulation and reducing ethanol-mediated oxidative stress.

Yuan-Jia Hu, J. Wan, Jiaolin Bao, 2015, Journal of agricultural and food chemistry.

Discrimination of Pterocephalus hookeri collected at flowering and non-flowering stages using GC-MS-based fatty acid profiling

J. Wan, Huanxing Su, Yi-Tao Wang, 2014 .

Schisantherin A Attenuates Neuroinflammation in Activated Microglia: Role of Nrf2 Activation Through ERK Phosphorylation

Chao Zhang, Chengwei He, Ying Zheng, 2018, Cellular Physiology and Biochemistry.

Polyphyllin VII Induces an Autophagic Cell Death by Activation of the JNK Pathway and Inhibition of PI3K/AKT/mTOR Pathway in HepG2 Cells

Peng Li, J. Wan, Jiaolin Bao, 2016, PloS one.

Melanoma growth is reduced in fat-1 transgenic mice: Impact of omega-6/omega-3 essential fatty acids

Chengwei He, J. Kang, Yan Lu, 2006, Proceedings of the National Academy of Sciences.

Omega-3 polyunsaturated fatty acids ameliorate ethanol-induced adipose hyperlipolysis: A mechanism for hepatoprotective effect against alcoholic liver disease.

M. Wang, J. Wan, Huanxing Su, 2017, Biochimica et biophysica acta. Molecular basis of disease.

Exploring protective effect of Glycine tabacina aqueous extract against nephrotic syndrome by network pharmacology and experimental verification

Chengwei He, Bing Han, Kai Wang, 2020, Chinese Medicine.

Inhibitory Effects of Betulinic Acid on LPS-Induced Neuroinflammation Involve M2 Microglial Polarization via CaMKKβ-Dependent AMPK Activation

Chao Zhao, Chao Zhang, Chengwei He, 2018, Front. Mol. Neurosci..

Dihydromyricetin Induces Apoptosis and Reverses Drug Resistance in Ovarian Cancer Cells by p53-mediated Downregulation of Survivin

Meiwan Chen, Chengwei He, Shengpeng Wang, 2017, Scientific Reports.

PCL–F68–PCL/PLGA–PEG–PLGA mixed micelles mediated delivery of mitoxantrone for reversing multidrug resistant in breast cancer

Xuesi Chen, J. Wan, Meiwan Chen, 2016 .

Label-Free Biomedical Imaging with High Sensitivity by Stimulated Raman Scattering Microscopy

Xiaohui Xie, Wei Min, J. Kang, 2008, Science.

ROS-Responsive Fluorinated Polyethyleneimine Vector to Co-Deliver shMTHFD2 and shGPX4 Plasmids Induces Ferroptosis and Apoptosis for Cancer Therapy

Meiwan Chen, Chengwei He, Hua Yu, 2021, Acta biomaterialia.

Effects of Coptis extract combined with chemotherapeutic agents on ROS production, multidrug resistance, and cell growth in A549 human lung cancer cells

Chengwei He, J. Kang, Keyuan Zhou, 2012, Chinese Medicine.

Endogenous n-3 Fatty Acids Alleviate Carbon-Tetrachloride-Induced Acute Liver Injury in Fat-1 Transgenic Mice

M. Wang, Peng Li, J. Wan, 2016, Oxidative Medicine and Cellular Longevity.

An integrated strategy to improve data acquisition and metabolite identification by time‐staggered ion lists in UHPLC/Q‐TOF MS‐based metabolomics

Yang Wang, J. Wan, Huanxing Su, 2018, Journal of pharmaceutical and biomedical analysis.

Hepatoprotective properties of Penthorum chinense Pursh against carbon tetrachloride-induced acute liver injury in mice

Yun Jiang, Peng Li, J. Wan, 2017, Chinese Medicine.

Gallic acid, a natural polyphenol, protects against tert-butyl hydroperoxide- induced hepatotoxicity by activating ERK-Nrf2-Keap1-mediated antioxidative response.

Yang Wang, Jian-Bo Wan, Chengwei He, 2017, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Characterizing plasma phospholipid fatty acid profiles of polycystic ovary syndrome patients with and without insulin resistance using GC-MS and chemometrics approach.

Peng Li, J. Wan, Huanxing Su, 2014, Journal of pharmaceutical and biomedical analysis.

E2F2 modulates cell adhesion through the transcriptional regulation of PECAM1 in multiple myeloma

Chengwei He, Zhigang Fang, O. Uziel, 2023, British journal of haematology.

Polysaccharides from mulberry (Morus alba L.) leaf prevents obesity by inhibiting pancreatic lipase in high-fat diet induced mice.

Haixia Chen, Min Zhang, Yajie Wang, 2021, International journal of biological macromolecules.

Forsythiae Fructus Inhibits B16 Melanoma Growth Involving MAPKs/Nrf2/HO-1 Mediated Anti-Oxidation and Anti-Inflammation.

Peng Li, J. Wan, Jiaolin Bao, 2016, The American journal of Chinese medicine.

The extract of huanglian, a medicinal herb, induces cell growth arrest and apoptosis by upregulation of interferon-β and TNF-α in human breast cancer cells

Chengwei He, Frederick P. Li, Chengwei He, 2005 .

Studies on the key constituents and the related mechanisms of Clerodendranthus spicatus in the treatment of diabetes based on network pharmacology.

Chengwei He, Haixia Chen, Nannan Li, 2022, Journal of ethnopharmacology.

Flavonoids from Rhynchosia minima root exerts anti-inflammatory activity in lipopolysaccharide-stimulated RAW 264.7 cells via MAPK/NF-κB signaling pathway

J. Wan, Jiaolin Bao, Chao Zhang, 2019, Inflammopharmacology.

Preparation, characterization, and anticancer efficacy of evodiamine-loaded PLGA nanoparticles

Yitao Wang, Jiaolin Bao, Lidi Zou, 2016, Drug delivery.

Review on the extraction, characterization and application of soybean polysaccharide

J. Wan, Meiwan Chen, Huanxing Su, 2015 .

Hormetic effect of panaxatriol saponins confers neuroprotection in PC12 cells and zebrafish through PI3K/AKT/mTOR and AMPK/SIRT1/FOXO3 pathways

Peng Li, J. Wan, Jiaolin Bao, 2017, Scientific Reports.

Niosome Encapsulation of Curcumin: Characterization and Cytotoxic Effect on Ovarian Cancer Cells

Peng Li, J. Wan, Meiwan Chen, 2016 .