J. Pike

发表

The Phosphorylated Estrogen Receptor α (ER) Cistrome Identifies a Subset of Active Enhancers Enriched for Direct ER-DNA Binding and the Transcription Factor GRHL2

Christopher L. Warren, E. Alarid, J. Pike, 2018, Molecular and Cellular Biology.

Regulation of gene expression by 1,25-dihydroxyvitamin D3 in bone cells: exploiting new approaches and defining new mechanisms.

J. Pike, M. Meyer, S. Lee, 2014, BoneKEy reports.

The vitamin D receptor: new paradigms for the regulation of gene expression by 1,25-dihydroxyvitamin D(3).

J. Pike, M. Meyer, J. Pike, 2010, Endocrinology and metabolism clinics of North America.

Epigenetic histone modifications and master regulators as determinants of context dependent nuclear receptor activity in bone cells.

J. Pike, M. Meyer, N. Benkusky, 2015, Bone.

Vitamin D and its analogs

Glenville Jones, J. Pike, J. W. Pike, 2020 .

The osteoblast to osteocyte transition: epigenetic changes and response to the vitamin D3 hormone.

Ning Leng, C. Kendziorski, L. Bonewald, 2014, Molecular endocrinology.

Analysis of estrogen receptor function in vitro reveals three distinct classes of antiestrogens.

J. Pike, D. McDonnell, M. Goldman, 1995, Molecular endocrinology.

Fundamentals of vitamin D hormone-regulated gene expression

J. Pike, M. Meyer, J. W. Pike, 2014, The Journal of Steroid Biochemistry and Molecular Biology.

Receptors for 1,25-dihydroxyvitamin D3 in chick pancreas: a partial physical and functional characterization.

J. Pike, J. Pike, 1982, Journal of steroid biochemistry.

Multifunctional enhancers regulate mouse and human vitamin D receptor gene transcription.

R. D. Nerenz, J. Pike, M. Meyer, 2010, Molecular endocrinology.

Vitamin D-binding protein influences total circulating levels of 1,25-dihydroxyvitamin D3 but does not directly modulate the bioactive levels of the hormone in vivo.

B. Hollis, J. Pike, Lee A. Zella, 2008, Endocrinology.

VDR/RXR and TCF4/β-catenin cistromes in colonic cells of colorectal tumor origin: impact on c-FOS and c-MYC gene expression.

J. Pike, M. Meyer, Paul D. Goetsch, 2012, Molecular endocrinology.

1,25-Dihydroxyvitamin D3-induced differentiation in a human promyelocytic leukemia cell line (HL-60): receptor-mediated maturation to macrophage-like cells

M. Haussler, D. Mangelsdorf, H. Koeffler, 1984, The Journal of cell biology.

Mouse and human BAC transgenes recapitulate tissue-specific expression of the vitamin D receptor in mice and rescue the VDR-null phenotype.

J. Goellner, C. O’Brien, J. Pike, 2014, Endocrinology.

Genome-Wide Perspectives on Vitamin D Receptor–Mediated Control of Gene Expression in Target Cells

J. Pike, M. Meyer, M. Onal, 2018 .

The vitamin D receptor and the syndrome of hereditary 1,25-dihydroxyvitamin D-resistant rickets.

J. Pike, P. Malloy, D. Feldman, 1999, Endocrine reviews.

Molecular biology of the vitamin D hormone.

B. Komm, J. Shine, M. Haussler, 1988, Recent progress in hormone research.

Receptors for 1,25-Dihydroxyvitamin D3: Structural Comparisons and Recent Functional Insights

M. Haussler, D. Mangelsdorf, J. Pike, 1987 .

Human estrogen receptor transactivational capacity is determined by both cellular and promoter context and mediated by two functionally distinct intramolecular regions.

M. Tzukerman, M. Parker, J. Pike, 1994, Molecular endocrinology.

Selective Distal Enhancer Control of the Mmp13 Gene Identified through Clustered Regularly Interspaced Short Palindromic Repeat (CRISPR) Genomic Deletions*

J. Pike, M. Meyer, N. Benkusky, 2015, The Journal of Biological Chemistry.

Functional domains of the human vitamin D3 receptor regulate osteocalcin gene expression.

B. O’Malley, J. Pike, R. Scott, 1989, Molecular endocrinology.

1,25-Dihydroxyvitamin D3 regulates the expression of low-density lipoprotein receptor-related protein 5 via deoxyribonucleic acid sequence elements located downstream of the start site of transcription.

Sungtae Kim, J. Pike, Lee A. Zella, 2006, Molecular endocrinology.

A humanized mouse model of hereditary 1,25-dihydroxyvitamin D-resistant rickets without alopecia.

J. Goellner, C. O’Brien, J. Pike, 2014, Endocrinology.

Mesenchymal Differentiation, Epigenetic Dynamics, and Interactions With VDR

J. Pike, M. Meyer, N. Benkusky, 2018 .

Enhancers located within two introns of the vitamin D receptor gene mediate transcriptional autoregulation by 1,25-dihydroxyvitamin D3.

Sungtae Kim, J. Pike, Lee A. Zella, 2006, Molecular endocrinology.

Activation of Receptor Activator of NF-κB Ligand Gene Expression by 1,25-Dihydroxyvitamin D3 Is Mediated through Multiple Long-Range Enhancers

Sungtae Kim, J. Pike, Lee A. Zella, 2006, Molecular and Cellular Biology.

Epigenetic Plasticity Drives Adipogenic and Osteogenic Differentiation of Marrow-derived Mesenchymal Stem Cells*

J. Rubin, B. Sen, J. Pike, 2016, The Journal of Biological Chemistry.

Targeted deletion of a distant transcriptional enhancer of the receptor activator of nuclear factor-kappaB ligand gene reduces bone remodeling and increases bone mass.

R. Weinstein, C. O’Brien, S. Manolagas, 2008, Endocrinology.

The vitamin D receptor: new paradigms for the regulation of gene expression by 1,25-dihydroxyvitamin D3.

J. Pike, M. Meyer, J. Pike, 2012, Rheumatic diseases clinics of North America.

Vitamin D3 receptors: structure and function in transcription.

J. Pike, J. W. Pike, J. Pike, 1991, Annual review of nutrition.

Selective regulation of Mmp13 by 1,25(OH)2D3, PTH, and Osterix through distal enhancers

J. Pike, M. Meyer, M. Onal, 2016, The Journal of Steroid Biochemistry and Molecular Biology.

Evidence for a role of prolactin in calcium homeostasis: regulation of intestinal transient receptor potential vanilloid type 6, intestinal calcium absorption, and the 25-hydroxyvitamin D(3) 1alpha hydroxylase gene by prolactin.

P. Dhawan, S. Christakos, J. Pike, 2010, Endocrinology.

The human transient receptor potential vanilloid type 6 distal promoter contains multiple vitamin D receptor binding sites that mediate activation by 1,25-dihydroxyvitamin D3 in intestinal cells.

Sungtae Kim, J. Pike, M. Meyer, 2006, Molecular endocrinology.

Neuropilin 2 in osteoblasts regulates trabecular bone mass in male mice

G. Carmeliet, M. Meyer, L. Verlinden, 2023, Frontiers in endocrinology.

Class 3 semaphorins are transcriptionally regulated by 1,25(OH)2D3 in osteoblasts

J. Pike, M. Meyer, L. Verlinden, 2017, The Journal of Steroid Biochemistry and Molecular Biology.

1,25-Dihydroxyvitamin D3-induced differentiation in a human promyelocytic leukemia cell line (HL-60): receptor-mediated maturation to macrophage-like cells

M. Haussler, D. Mangelsdorf, H. Koeffler, 1984, The Journal of cell biology.

Vitamin D-binding protein influences total circulating levels of 1,25-dihydroxyvitamin D3 but does not directly modulate the bioactive levels of the hormone in vivo.

B. Hollis, Lee A. Zella, N. Cooke, 2008, Endocrinology.

Regulation of mouse Cyp24a1 expression via promoter-proximal and downstream-distal enhancers highlights new concepts of 1,25-dihydroxyvitamin D(3) action.

J. Pike, M. Meyer, J. Pike, 2012, Archives of biochemistry and biophysics.

Genome-wide principles of gene regulation by the vitamin D receptor and its activating ligand

J. Pike, J. Pike, 2011, Molecular and Cellular Endocrinology.

A Novel Distal Enhancer Mediates Inflammation‐, PTH‐, and Early Onset Murine Kidney Disease‐Induced Expression of the Mouse Fgf23 Gene

J. Pike, M. Meyer, M. Onal, 2017, JBMR plus.

Molecular structure of the rat vitamin D receptor ligand binding domain complexed with 2-carbon-substituted vitamin D3 hormone analogues and a LXXLL-containing coactivator peptide.

H. DeLuca, M. Benning, J. Vanhooke, 2004, Biochemistry.

Biology and Mechanisms of Action of the Vitamin D Hormone.

S. Christakos, J. Pike, J. Pike, 2017, Endocrinology and metabolism clinics of North America.

The impact of VDR expression and regulation in vivo

C. O’Brien, J. Pike, M. Meyer, 2017, The Journal of Steroid Biochemistry and Molecular Biology.

The vitamin D receptor functions as a transcription regulator in the absence of 1,25-dihydroxyvitamin D3

J. Pike, S. Lee, S. M. Lee, 2016, The Journal of Steroid Biochemistry and Molecular Biology.

1,25-Dihydroxyvitamin D3 Controls a Cohort of Vitamin D Receptor Target Genes in the Proximal Intestine That Is Enriched for Calcium-regulating Components*

M. Meyer, L. Plum, N. Benkusky, 2015, The Journal of Biological Chemistry.

A chromatin-based mechanism controls differential regulation of the cytochrome P450 gene Cyp24a1 in renal and non-renal tissues

Glenville Jones, J. Pike, M. Meyer, 2019, The Journal of Biological Chemistry.

Genomic Determinants of Gene Regulation by 1,25-Dihydroxyvitamin D3 during Osteoblast-lineage Cell Differentiation*♦

J. Pike, M. Meyer, Chang-Hun Lee, 2014, The Journal of Biological Chemistry.

Fundamentals of vitamin D hormone-regulated gene expression

M. Meyer, J. Pike, 2014, The Journal of Steroid Biochemistry and Molecular Biology.

A Downstream Intergenic Cluster of Regulatory Enhancers Contributes to the Induction of CYP24A1 Expression by 1α,25-Dihydroxyvitamin D3*

J. Pike, M. Meyer, Paul D. Goetsch, 2010, The Journal of Biological Chemistry.

Epigenetic Plasticity Drives Adipogenic and Osteogenic Differentiation of Marrow-derived Mesenchymal Stem Cells*

J. Rubin, M. Meyer, N. Benkusky, 2016, The Journal of Biological Chemistry.

Corepressors (NCoR and SMRT) as well as coactivators are recruited to positively regulated 1α,25-dihydroxyvitamin D3-responsive genes

M. Meyer, J. Pike, 2013, The Journal of Steroid Biochemistry and Molecular Biology.

Serum and monoclonal antibodies against the chick intestinal receptor for 1,25-dihydroxyvitamin D3. Generation by a preparation enriched in a 64,000-dalton protein.

M. Haussler, S. Marion, J. Pike, 1983, The Journal of biological chemistry.

Regulation of target gene expression by the vitamin D receptor - an update on mechanisms

J. Pike, M. Meyer, Kathleen A. Bishop, 2012, Reviews in Endocrine and Metabolic Disorders.

1,25-Dihydroxyvitamin D3 and the aging-related Forkhead Box O and Sestrin proteins in osteoblasts

R. Bouillon, G. Eelen, R. Gijsbers, 2013, The Journal of Steroid Biochemistry and Molecular Biology.

The RUNX2 Cistrome in Osteoblasts

J. Pike, M. Meyer, N. Benkusky, 2014, The Journal of Biological Chemistry.

Deletion of a Distal RANKL Gene Enhancer Delays Progression of Atherosclerotic Plaque Calcification in Hypercholesterolemic Mice

J. Pike, M. Onal, Sohel Shamsuzzaman, 2017, Journal of cellular biochemistry.

Genomic Mechanisms Governing Mineral Homeostasis and the Regulation and Maintenance of Vitamin D Metabolism

J. Pike, M. Meyer, S. Lee, 2020, JBMR plus.

Vitamin D receptor-mediated gene regulation mechanisms and current concepts of vitamin D analog selectivity.

J. Pike, Hironori Yamamoto, N. Shevde, 2002, Advances in renal replacement therapy.

Positive regulation of the vitamin D receptor by its cognate ligand in heterologous expression systems.

J. Pike, D. McDonnell, G. Hilliard, 1993, Molecular endocrinology.

A kidney-specific genetic control module in mice governs endocrine regulation of the cytochrome P450 gene Cyp27b1 essential for vitamin D3 activation

Glenville Jones, M. Meyer, M. Onal, 2017, The Journal of Biological Chemistry.

Targeted genomic deletions identify diverse enhancer functions and generate a kidney-specific, endocrine-deficient Cyp27b1 pseudo-null mouse

R. Redfield, Glenville Jones, J. Pike, 2019, The Journal of Biological Chemistry.

Emerging regulatory paradigms for control of gene expression by 1,25-dihydroxyvitamin D3

R. D. Nerenz, J. Pike, M. Meyer, 2010, The Journal of Steroid Biochemistry and Molecular Biology.

Vitamin D Significantly Inhibits Carcinogenesis in the Mogp-TAg Mouse Model of Fallopian Tube Ovarian Cancer

Gayathriy Balamayooran, J. Turbov, R. Rosales, 2024, Nutrients.