Christine L. Clarke

发表

Estrogen and progesterone signalling in the normal breast and its implications for cancer development

J. Graham, C. Clarke, H. Hilton, 2017, Molecular and Cellular Endocrinology.

Loss of Co-ordinate Expression of Progesterone Receptors A and B is an Early Event in Breast Carcinogenesis

N. Tran, N. Tran, C. Clarke, 2002, Breast Cancer Research and Treatment.

Histone deacetylase inhibitors decrease proliferation and modulate cell cycle gene expression in normal mammary epithelial cells.

Y. Chiew, A. deFazio, C. Clarke, 2000, Clinical cancer research : an official journal of the American Association for Cancer Research.

A case-only study to identify genetic modifiers of breast cancer risk for BRCA1/BRCA2 mutation carriers

Jane E. Carpenter, Jack A. Taylor, W. Chung, 2021, Nature Communications.

Progestin regulation of cellular proliferation.

C. Clarke, R. Sutherland, Christine L. Clarke, 1990, Endocrine reviews.

Colocalization of progesterone receptors A and B by dual immunofluorescent histochemistry in human endometrium during the menstrual cycle.

C. Clarke, R. Balleine, E. McGowan, 1999, The Journal of clinical endocrinology and metabolism.

Polygenic Risk Scores for Prediction of Breast Cancer and Breast Cancer Subtypes

Kristen S Purrington, Jack A. Taylor, A. Whittemore, 2018, American Journal of Human Genetics.

Imatinib Disposition and ABCB1 (MDR1, P‐Glycoprotein) Genotype

G. Mann, C. Clarke, R. Balleine, 2007, Clinical pharmacology and therapeutics.

Effect of medroxyprogesterone acetate on proliferation and cell cycle kinetics of human mammary carcinoma cells.

C. Clarke, R. Sutherland, E. Musgrove, 1988, Cancer research.

DNA replication licensing and progenitor numbers are increased by progesterone in normal human breast.

J. Graham, C. Clarke, R. Balleine, 2009, Endocrinology.

Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes

Jane E. Carpenter, Jack A. Taylor, W. Chung, 2019, Nature Genetics.

Expression and regulation of retinoic acid receptors in human breast cancer cells.

C. Clarke, R. Sutherland, I. Alexander, 1992, Cancer research.

A tumour suppressive relationship between mineralocorticoid and retinoic acid receptors activates a transcriptional program consistent with a reverse Warburg effect in breast cancer

J. Graham, M. Young, J. Funder, 2020, Breast cancer research : BCR.

Acquired convergence of hormone signaling in breast cancer: ER and PR transition from functionally distinct in normal breast to predictors of metastatic disease

J. Graham, C. Clarke, W. Tilley, 2014, Oncotarget.

Decreased progesterone binding and attenuated progesterone action in cultured human breast carcinoma cells treated with epidermal growth factor.

W. Blattner, J. Nadeau, C. Pui, 1988, Cancer research.

The antiproliferative effects of progestins in T47D breast cancer cells are tempered by progestin induction of the ETS transcription factor Elf5.

J. Graham, C. Clarke, Heather J. Lee, 2010, Molecular endocrinology.

Focal subnuclear distribution of progesterone receptor is ligand dependent and associated with transcriptional activity.

J. Graham, C. Clarke, L. Scurr, 2007, Molecular endocrinology.

Progesterone receptor A predominance is a discriminator of benefit from endocrine therapy in the ATAC trial

J. Cuzick, K. Byth, M. Dowsett, 2015, Breast Cancer Research and Treatment.

Progesterone stimulates progenitor cells in normal human breast and breast cancer cells

J. Graham, C. Clarke, L. Huschtscha, 2014, Breast Cancer Research and Treatment.

Progesterone receptors - animal models and cell signaling in breast cancer: Expression and transcriptional activity of progesterone receptor A and progesterone receptor B in mammalian cells

J. Graham, C. Clarke, Christine L. Clarke, 2002, Breast Cancer Research.

Relative expression of progesterone receptors A and B in endometrioid cancers of the endometrium.

K. Byth, A. deFazio, C. Clarke, 2001, Cancer research.

Progesterone receptor isoforms in normal and malignant breast.

J. Graham, C. Clarke, P. Mote, 2007, Ernst Schering Foundation symposium proceedings.

Minireview: Progesterone Regulation of Proliferation in the Normal Human Breast and in Breast Cancer: A Tale of Two Scenarios?

J. Graham, C. Clarke, H. Hilton, 2015, Molecular endocrinology.

The Nuclear Receptor, RORγ, Regulates Pathways Necessary for Breast Cancer Metastasis

Bipul R. Acharya, J. Graham, C. Clarke, 2016, EBioMedicine.

Physiological action of progesterone in target tissues.

J. Graham, C. Clarke, Christine L. Clarke, 1997, Endocrine reviews.

Emerging functional roles of nuclear receptors in breast cancer.

J. Graham, C. Clarke, T. Doan, 2017, Journal of molecular endocrinology.

Altered progesterone receptor isoform expression remodels progestin responsiveness of breast cancer cells.

K. Byth, J. Graham, M. L. Yager, 2005, Molecular endocrinology.

Polygenic Risk Scores for Prediction of Breast Cancer and Breast Cancer Subtypes

Kristen S Purrington, Jack A. Taylor, A. Whittemore, 2018, American Journal of Human Genetics.

Characterization of progesterone receptor A and B expression in human breast cancer.

J. Graham, R. Balleine, A. Bilous, 1995, Cancer research.

Progesterone receptors - animal models and cell signaling in breast cancer: Expression and transcriptional activity of progesterone receptor A and progesterone receptor B in mammalian cells

J. Graham, D. Marušič, Christine L. Clarke, 2002, Breast Cancer Research.

Detection of progesterone receptor forms A and B by immunohistochemical analysis

C. Clarke, P. Tuohimaa, P. Mote, 2001, Journal of clinical pathology.

Effect of overexpression of progesterone receptor A on endogenous progestin-sensitive endpoints in breast cancer cells.

C. Clarke, E. McGowan, Christine L. Clarke, 1999, Molecular endocrinology.

Progestin inhibition of progesterone receptor gene expression in human breast cancer cells.

J. Shine, C. Clarke, R. Sutherland, 1989, Molecular endocrinology.

Estradiol induction of retinoic acid receptors in human breast cancer cells.

R. Blamey, R. Nicholson, C. Clarke, 1993, Cancer research.

Progesterone and estrogen receptors segregate into different cell subpopulations in the normal human breast

J. Graham, C. Clarke, L. Huschtscha, 2012, Molecular and Cellular Endocrinology.

Hormone-Responsive Model of Primary Human Breast Epithelium

J. Graham, C. Clarke, R. Balleine, 2009, Journal of Mammary Gland Biology and Neoplasia.

Heterogeneity of progesterone receptors A and B expression in human endometrial glands and stroma.

C. Clarke, R. Balleine, E. McGowan, 2000, Human reproduction.