Inkyu Hwang

发表

Mechanisms of tumor-induced T cell immune suppression and therapeutics to counter those effects

I. Hwang, Nguyet Nguyen, Inkyu Hwang, 2015, Archives of pharmacal research.

Mechanisms of tumor-induced T cell immune suppression and therapeutics to counter those effects

I. Hwang, Nguyet Nguyen, Inkyu Hwang, 2015, Archives of Pharmacal Research.

Chemical constituents of Vietnamese mangrove Hibiscus tiliaceus with antioxidant and alpha-glucosidase inhibitory activity

Le Ba Vinh, Y. H. Kim, N. P. Thao, 2019, Natural product research.

Evaluation of Chlorofusin, its Seven Chromophore Diastereomers, and Key Analogues.

D. Boger, M. Searcey, I. Hwang, 2009, Tetrahedron letters.

Potent and selective stimulation of memory-phenotype CD8+ T cells in vivo by IL-15.

J. Sprent, D. Tough, Siquan Sun, 1998, Immunity.

TCR-Mediated internalization of peptide-MHC complexes acquired by T cells.

M. Jackson, P. A. Peterson, J. Sprent, 1999, Science.

Direct stimulation of naïve T cells by membrane vesicles from antigen-presenting cells: Distinct roles for CD54 and B7 molecules

J. Sprent, Xuefei Shen, I. Hwang, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Synthesis and biological evaluation of alpha- and gamma-carboxamide derivatives of 10-CF3CO-DDACTHF.

D. Boger, I. Wilson, S. Benkovic, 2005, Bioorganic & medicinal chemistry.

T Cells Can Use Either T Cell Receptor or Cd28 Receptors to Absorb and Internalize Cell Surface Molecules Derived from Antigen-Presenting Cells

M. Jackson, P. A. Peterson, J. Sprent, 2000, The Journal of experimental medicine.

Design, synthesis, and evaluation of an alpha-helix mimetic library targeting protein-protein interactions.

Sukwon Hong, Mark Searcey, Dale L Boger, 2009, Journal of the American Chemical Society.

Discovery of AICAR Tfase inhibitors that disrupt requisite enzyme dimerization.

Dale L Boger, D. Boger, Romyr Dominique, 2005, Bioorganic & medicinal chemistry letters.

Crucial role of miR-31 in induction of CD8+ T-cell exhaustion and reinforcement of type 1 interferon signaling

Lin Ying Li, Inkyu Hwang, 2018, Cellular & Molecular Immunology.

Absorption and Internalization of Ligands Role of the Actin Cytoskeleton in T Cell

I. Hwang, Inkyu Hwang, 2001 .

Structure−Activity Relationships of α-Ketooxazole Inhibitors of Fatty Acid Amide Hydrolase

D. Boger, B. Cravatt, F. A. Romero, 2007 .

Potent and Selective α-Ketoheterocycle-Based Inhibitors of the Anandamide and Oleamide Catabolizing Enzyme, Fatty Acid Amide Hydrolase

Benjamin F. Cravatt, Dale L. Boger, D. Boger, 2007 .

Potent and selective alpha-ketoheterocycle-based inhibitors of the anandamide and oleamide catabolizing enzyme, fatty acid amide hydrolase.

D. Boger, Heather S Hoover, B. Cravatt, 2007, Journal of medicinal chemistry.

Structure-activity relationships of alpha-ketooxazole inhibitors of fatty acid amide hydrolase.

D. Boger, B. Cravatt, F. A. Romero, 2007, Journal of medicinal chemistry.

Total synthesis of vinblastine, vincristine, related natural products, and key structural analogues.

Hayato Ishikawa, Dale L. Boger, D. Boger, 2009, Journal of the American Chemical Society.

A new rearranged abietane diterpene from Clerodendrum inerme with antioxidant and cytotoxic activities

C. Van Minh, Nguyen Van Thanh, I. Hwang, 2018, Natural product research.

Enhancement of an In Vivo Anti-Inflammatory Activity of Oleanolic Acid through Glycosylation Occurring Naturally in Stauntonia hexaphylla

Le Ba Vinh, L. Ye, Y. H. Kim, 2020, Molecules.

Optimization of the central heterocycle of alpha-ketoheterocycle inhibitors of fatty acid amide hydrolase.

D. Boger, C. Ezzili, Dustin G Hochstatter, 2008, Journal of medicinal chemistry.

The mast cell stabilizing activity of Chaga mushroom critical for its therapeutic effect on food allergy is derived from inotodiol

J. Lee, J. Kang, I. Hwang, 2018, International immunopharmacology.

Cell-cell communication via extracellular membrane vesicles and its role in the immune response

I. Hwang, Inkyu Hwang, 2013, Molecules and cells.

Total synthesis of piericidin A1 and B1 and key analogues.

D. Boger, T. Yagi, F. A. Romero, 2006, Journal of the American Chemical Society.

Optimization of alpha-ketooxazole inhibitors of fatty acid amide hydrolase.

Dale L Boger, D. Boger, F. A. Romero, 2008, Journal of medicinal chemistry.

Discovery of a potent, selective, and efficacious class of reversible alpha-ketoheterocycle inhibitors of fatty acid amide hydrolase effective as analgesics.

D. Boger, W. L. Jorgensen, O. Acevedo, 2005, Journal of medicinal chemistry.

Discovery of an exceptionally potent and selective class of fatty acid amide hydrolase inhibitors enlisting proteome-wide selectivity screening: concurrent optimization of enzyme inhibitor potency and selectivity.

D. Boger, B. Cravatt, D. Leung, 2005, Bioorganic & medicinal chemistry letters.

Heterocyclic sulfoxide and sulfone inhibitors of fatty acid amide hydrolase.

D. Boger, C. Hardouin, Wu Du, 2005, Bioorganic & medicinal chemistry letters.

Optimization of α -Ketooxazole Inhibitors of Fatty Acid Amide Hydrolase

D. Boger, F. A. Romero, C. Ezzili, 2009 .

Synthesis and evaluation of methyl ether derivatives of the vancomycin, teicoplanin, and ristocetin aglycon methyl esters.

D. Boger, I. Hwang, B. Crowley, 2003, Bioorganic & medicinal chemistry letters.

Receptor-mediated T cell absorption of antigen presenting cell-derived molecules.

I. Hwang, Dalim Ki, Inkyu Hwang, 2011, Frontiers in bioscience.

LFA-1-dependent Ca2+ Entry following Suboptimal T Cell Receptor Triggering Proceeds without Mobilization of Intracellular Ca2+*

I. Hwang, Kwangmi Kim, Lin Wang, 2009, The Journal of Biological Chemistry.

Mechanisms of tumor-induced T cell immune suppression and therapeutics to counter those effects

Nguyet Nguyen, Inkyu Hwang, 2015, Archives of Pharmacal Research.

Acute Inhibition of Selected Membrane-Proximal Mouse T Cell Receptor Signaling by Mitochondrial Antagonists

I. Hwang, Kwangmi Kim, Lin Wang, 2009, PloS one.

Total synthesis of vinblastine, vincristine, related natural products, and key structural analogues.

D. Boger, H. Ishikawa, H. Kakei, 2009, Journal of the American Chemical Society.

Fundamental role of the fostriecin unsaturated lactone and implications for selective protein phosphatase inhibition.

D. Boger, C. Gauss, S. Ichikawa, 2003, Journal of the American Chemical Society.

Rational design, synthesis, and evaluation of key analogues of CC-1065 and the duocarmycins.

D. Boger, A. Zaid, P. Baraldi, 2007, Journal of the American Chemical Society.

Optimization of the central heterocycle of alpha-ketoheterocycle inhibitors of fatty acid amide hydrolase.

D. Boger, C. Ezzili, T. Rayl, 2008, Journal of medicinal chemistry.

Potentiation of T Cell Stimulatory Activity by Chemical Fixation of a Weak Peptide-MHC Complex

I. Hwang, Kwangmi Kim, M. Lomunova, 2017, Molecules and cells.

Design, synthesis, and biological evaluation of 10-methanesulfonyl-DDACTHF, 10-methanesulfonyl-5-DACTHF, and 10-methylthio-DDACTHF as potent inhibitors of GAR Tfase and the de novo purine biosynthetic pathway.

D. Boger, I. Wilson, S. Benkovic, 2005, Bioorganic & medicinal chemistry.

Synthesis and biological evaluation of N-[4-[5-(2,4-diamino-6-oxo-1,6-dihydropyrimidin-5-yl)-2-(2,2,2-trifluoroacetyl)pentyl]benzoyl]-L-glutamic acid as a potential inhibitor of GAR Tfase and the de novo purine biosynthetic pathway.

D. Boger, I. Wilson, S. Benkovic, 2005, Bioorganic & medicinal chemistry.

Direct stimulation of T cells by membrane vesicles from antigen-presenting cells.

J. Sprent, O. Boyman, Xuefei Shen, 2006, Proceedings of the National Academy of Sciences of the United States of America.

Development of an oral immunoadjuvant from cheonggukjang that is efficacious for both mucosal and systemic immunity

I. Chung, Seong-Il Lim, D. Shon, 2014, Food Science and Biotechnology.

Systematic exploration of the structural features of yatakemycin impacting DNA alkylation and biological activity.

D. Boger, Karen S Macmillan, Mark S Tichenor, 2007, Journal of the American Chemical Society.

Asymmetric Total Synthesis of (+)- and ent-(-)-Yatakemycin (I) and Duocarmycin SA (II): Evaluation of Yatakemycin Key Partial Structures and Its Unnatural Enantiomer.

D. Boger, F. Shiga, Mark S Tichenor, 2007 .

Asymmetric total synthesis of (+)- and ent-(-)-yatakemycin and duocarmycin SA: evaluation of yatakemycin key partial structures and its unnatural enantiomer.

D. Boger, F. Shiga, Mark S Tichenor, 2006, Journal of the American Chemical Society.

Structure-based Design, Synthesis, Evaluation, and Crystal Structures of Transition State Analogue Inhibitors of Inosine Monophosphate Cyclohydrolase*

D. Boger, I. Wilson, A. Olson, 2007, Journal of Biological Chemistry.

Delineation of a fundamental alpha-ketoheterocycle substituent effect for use in the design of enzyme inhibitors.

D. Boger, F. A. Romero, I. Hwang, 2006, Journal of the American Chemical Society.

A Novel Flow Cytometric High Throughput Assay for a Systematic Study on Molecular Mechanisms Underlying T Cell Receptor-Mediated Integrin Activation

Kwangmi Kim, Lin Wang, Inkyu Hwang, 2009, PloS one.

Anti-allergic effect of inotodiol, a lanostane triterpenoid from Chaga mushroom, via selective inhibition of mast cell function.

Y. H. Kim, I. Hwang, Thi Minh Nguyet Nguyen, 2020, International immunopharmacology.

Inotodiol, an antiasthmatic agent with efficacy and safety, preferentially impairs membrane-proximal signaling for mast cell activation.

J. Kang, I. Hwang, Rema Naskar, 2023, International immunopharmacology.

Synthesis and evaluation of N-aryl and N-alkenyl CBI derivatives.

D. Boger, T. V. Hughes, I. Hwang, 2004, Bioorganic & medicinal chemistry.