Amity L Manning

发表

Aurora A inhibition limits centrosome clustering and promotes mitotic catastrophe in cells with supernumerary centrosomes

A. Manning, Nicole M. Hermance, Dayna L. Mercadante, 2018, bioRxiv.

SnapShot: Nonmotor Proteins in Spindle Assembly

D. Compton, Amity L Manning, 2008, Cell.

PUMILIO competes with AUF1 to control DICER1 RNA levels and miRNA processing

Jalal K. Siddiqui, S. Bouley, A. Gerber, 2022, Nucleic acids research.

Proteomic analysis of pRb loss highlights a signature of decreased mitochondrial oxidative phosphorylation

W. Haas, J. Lapek, R. Morris, 2015, Genes & development.

Suppression of chromosome instability limits acquired drug resistance

A. Manning, Elizabeth A Crowley, Conor P Herlihy, 2020, bioRxiv.

Enhanced cohesion promotes chromosome stability and limits acquired drug resistance in non small cell lung cancer

A. Manning, Elizabeth A Crowley, Conor P Herlihy, 2020 .

Whole genome doubling confers unique genetic vulnerabilities on tumor cells

Joshua D. Campbell, Neil J Ganem, Alison M. Taylor, 2020, Nature.

H4K20 methylation regulates quiescence and chromatin compaction

H. Coller, B. Garcia, N. Dyson, 2013, Molecular biology of the cell.

A Novel Retinoblastoma Therapy from Genomic and Epigenetic Analyses

Matthew W. Wilson, Michael C. Rusch, R. Wilson, 2011, Nature.

A conserved mechanism for Bni1- and mDia1-induced actin assembly and dual regulation of Bni1 by Bud6 and profilin.

D. Pellman, M. Eck, J. Moseley, 2003, Molecular biology of the cell.

Genome stability is ensured by temporal control of kinetochore-microtubule dynamics

Samuel F. Bakhoum, Duane A. Compton, D. Compton, 2008, Nature Cell Biology.

The kinesin-13 proteins Kif2a, Kif2b, and Kif2c/MCAK have distinct roles during mitosis in human cells.

D. Compton, S. Bakhoum, M. Wagenbach, 2007, Molecular biology of the cell.

Phase I study of the aurora A kinase inhibitor alisertib with induction chemotherapy in patients with acute myeloid leukemia

D. Neuberg, T. Graubert, K. Ballen, 2016, Haematologica.

KDM4A Lysine Demethylase Induces Site-Specific Copy Gain and Rereplication of Regions Amplified in Tumors

Gad Getz, Kimberly Glass, Capucine Van Rechem, 2013, Cell.

Suv420 enrichment at the centromere limits Aurora B localization and function

A. Manning, Nicole M. Hermance, Sabine S. C. Hahn, 2021, bioRxiv.

Identification of the kinase STK25 as an upstream activator of LATS signaling

Sanghee Lim, Ryan J. Quinton, A. Manning, 2019, Nature Communications.

RB: mitotic implications of a tumour suppressor

N. Dyson, A. Manning, Nicholas J. Dyson, 2012, Nature Reviews Cancer.

pRB, a tumor suppressor with a stabilizing presence.

N. Dyson, A. Manning, Amity L Manning, 2011, Trends in cell biology.

Loss of pRB causes centromere dysfunction and chromosomal instability.

N. Dyson, A. Manning, M. Longworth, 2010, Genes & development.

CLASP1, astrin and Kif2b form a molecular switch that regulates kinetochore‐microtubule dynamics to promote mitotic progression and fidelity

D. Compton, S. Bakhoum, H. Maiato, 2010, The EMBO journal.

Whole chromosome instability resulting from the synergistic effects of pRB and p53 inactivation

C. Benes, N. Dyson, A. Manning, 2014, Oncogene.

Motor-Independent Targeting of CLASPs to Kinetochores by CENP-E Promotes Microtubule Turnover and Poleward Flux

A. Hyman, J. Yates, A. Shevchenko, 2009, Current Biology.

Mechanisms of Spindle-Pole Organization Are Influenced by Kinetochore Activity in Mammalian Cells

D. Compton, A. Manning, Amity L Manning, 2007, Current Biology.

Negative Regulation of Yeast WASp by Two SH3 Domain-Containing Proteins

A. Rodal, D. Drubin, A. Manning, 2003, Current Biology.

Suppression of genome instability in pRB-deficient cells by enhancement of chromosome cohesion.

N. Dyson, L. Zou, Brandon Nicolay, 2014, Molecular cell.

RB loss sensitizes cells to replication-associated DNA damage by PARP inhibition

Himabindu Gali, A. Manning, M. Pruitt, 2023, bioRxiv.

Defining Cell Cycle‐Specific Interactions of the pRB Tumor Suppressor

A. Manning, Emily Jane Stadnicki, Amity L Manning, 2020, The FASEB Journal.

Alisertib plus induction chemotherapy in previously untreated patients with high-risk, acute myeloid leukaemia: a single-arm, phase 2 trial.

Traci M. Blonquist, D. Neuberg, T. Graubert, 2019, The Lancet. Haematology.

RB loss sensitizes cells to replication-associated DNA damage after PARP inhibition by trapping

Himabindu Gali, R. L. Flynn, L. G. Zamalloa, 2023, Life science alliance.

Modeling reveals cortical dynein-dependent fluctuations in bipolar spindle length.

S. Olson, Dayna L. Mercadante, Amity L Manning, 2021, Biophysical journal.

Modeling reveals cortical dynein-dependent oscillations in bipolar spindle length

S. Olson, A. Manning, Dayna L. Mercadante, 2020, bioRxiv.

Live Cell Imaging to Assess the Dynamics of Metaphase Timing and Cell Fate Following Mitotic Spindle Perturbations.

Dayna L. Mercadante, Elizabeth A Crowley, Amity L Manning, 2019, Journal of visualized experiments : JoVE.

CRL4(Cdt2)-mediated destruction of the histone methyltransferase Set8 prevents premature chromatin compaction in S phase.

N. Dyson, L. Zou, Jianping Jin, 2010, Molecular cell.

Structural and regulatory roles of nonmotor spindle proteins.

D. Compton, A. Manning, Amity L Manning, 2008, Current opinion in cell biology.

STK25 directly activates LATS1/2 independent of MST/MAP4Ks

Sanghee Lim, Ryan J. Quinton, A. Manning, 2018, bioRxiv.