Moran Rubinstein

发表

A novel EWS-WT1 gene fusion product in desmoplastic small round cell tumor is a potent transactivator of the insulin-like growth factor-I receptor (IGF-IR) gene.

H. Werner, C. Roberts, M. Rubinstein, 2007, Cancer letters.

Transcriptional activation of the insulin-like growth factor I receptor gene by the Kruppel-like factor 6 (KLF6) tumor suppressor protein: potential interactions between KLF6 and p53.

S. Friedman, S. Plymate, H. Werner, 2004, Endocrinology.

Exogenous NaV1.1 activity in excitatory and inhibitory neurons reverts Dravet syndrome comorbidities when delivered post-symptom onset in mice with Dravet

Ethan M. Goldberg, M. Rubinstein, E. Kremer, 2022, bioRxiv.

Functional Investigation of a Neuronal Microcircuit in the CA1 Area of the Hippocampus Reveals Synaptic Dysfunction in Dravet Syndrome Mice

M. Rubinstein, M. Brusel, Y. Almog, 2022, Frontiers in Molecular Neuroscience.

Transfer of SCN1A to the brain of adolescent mouse model of Dravet syndrome improves epileptic, motor, and behavioral manifestations

M. Valencia, M. Rubinstein, G. González-Aseguinolaza, 2021, Molecular therapy. Nucleic acids.

Developmental alterations in firing properties of hippocampal CA1 inhibitory and excitatory neurons in a mouse model of Dravet syndrome

M. Rubinstein, M. Brusel, Y. Almog, 2020, Neurobiology of Disease.

Early EEG and behavioral alterations in Dravet mice

M. Rubinstein, D. Yakubovich, K. Anderson, 2020, bioRxiv.

Early hippocampal hyperexcitability followed by disinhibition in a mouse model of Dravet syndrome

M. Brusel, Y. Almog, K. Anderson, 2019, bioRxiv.

Dissecting the phenotypes of Dravet syndrome by gene deletion.

W. Catterall, Sung Han, M. Rubinstein, 2015, Brain : a journal of neurology.

Mitochondrial Regulation of the Hippocampal Firing Rate Set Point and Seizure Susceptibility

E. Ruppin, Boaz Styr, I. Vertkin, 2019, Neuron.

Striatin Is Required for Hearing and Affects Inner Hair Cells and Ribbon Synapses

A. Dror, K. Avraham, R. Lang, 2020, bioRxiv.

A Quantitative Model of the GIRK1/2 Channel Reveals That Its Basal and Evoked Activities Are Controlled by Unequal Stoichiometry of Gα and Gβγ

Daniel Yakubovich, Shai Berlin, Uri Kahanovitch, 2015, PLoS Comput. Biol..

Gαi3 primes the G protein‐activated K+ channels for activation by coexpressed Gβγ in intact Xenopus oocytes

N. Dascal, M. Rubinstein, Shai Berlin, 2007 .

Heat-induced seizures, premature mortality, and hyperactivity in a novel Scn1a nonsense model for Dravet syndrome

V. Dani, M. Rubinstein, M. Brusel, 2023, bioRxiv.

Acute effect of antiseizure drugs on background oscillations in Scn1a A1783V Dravet syndrome mouse model

M. Brusel, Shir Quinn, Mor Ovadia, 2022, bioRxiv.

Convulsive seizures and some behavioral comorbidities are uncoupled in the Scn1aA1783V Dravet syndrome mouse model

M. Giladi, M. Rubinstein, D. Yakubovich, 2020, Epilepsia.

Genetic background modulates impaired excitability of inhibitory neurons in a mouse model of Dravet syndrome

W. Catterall, M. Rubinstein, T. Scheuer, 2015, Neurobiology of Disease.

Association of rare missense variants in the second intracellular loop of NaV1.7 sodium channels with familial autism

E. Wijsman, W. Catterall, R. Bernier, 2016, Molecular Psychiatry.

Novel ADNP Syndrome Mice Reveal Dramatic Sex-Specific Peripheral Gene Expression With Brain Synaptic and Tau Pathologies

N. Shomron, M. Rubinstein, G. Hacohen-Kleiman, 2021, Biological Psychiatry.

Recruitment of Gβγ controls the basal activity of G‐protein coupled inwardly rectifying potassium (GIRK) channels: crucial role of distal C terminus of GIRK1

Boaz Styr, C. Dessauer, N. Dascal, 2014, The Journal of physiology.

Gαi and Gβγ Jointly Regulate the Conformations of a Gβγ Effector, the Neuronal G Protein-activated K+ Channel (GIRK)*

C. Dessauer, N. Dascal, M. Rubinstein, 2009, The Journal of Biological Chemistry.

Divergent regulation of GIRK1 and GIRK2 subunits of the neuronal G protein gated K+ channel by GαiGDP and Gβγ

C. Dessauer, N. Dascal, Shai Berlin, 2009, The Journal of physiology.

Reciprocal Changes in Phosphorylation and Methylation of Mammalian Brain Sodium Channels in Response to Seizures*

Je-Hyun Baek, Moran Rubinstein, James S Trimmer, 2014, The Journal of Biological Chemistry.

Genetic background modulates impaired excitability of inhibitory neurons in a mouse model of Dravet syndrome

W. Catterall, T. Scheuer, R. Westenbroek, 2015, Neurobiology of Disease.

Viral vector–mediated expression of NaV1.1, after seizure onset, reduces epilepsy in mice with Dravet syndrome

Ethan M. Goldberg, E. Kremer, Bertrand Beucher, 2023, The Journal of clinical investigation.

Lithium reduces the span of G protein‐activated K+ (GIRK) channel inhibition in hippocampal neurons

N. Dascal, Moran Rubinstein, 2017, Bipolar disorders.

Complex biophysical changes and reduced neuronal firing in an SCN8A variant associated with developmental delay and epilepsy

H. Bassan, Y. Haitin, Roy Ben-Shalom, 2023, bioRxiv.

The SCN8A p.(Gly1625Arg) variant associated with developmental and epileptic encephalopathy causes complex biophysical changes and reduced neuronal firing

H. Bassan, Y. Haitin, Roy Ben-Shalom, 2022 .

In vivo, in vitro and in silico correlations of four de novo SCN1A missense mutations

M. Rubinstein, B. Ben-Zeev, M. Brusel, 2019, PloS one.

Reprogramming of two induced pluripotent stem cell lines from a heterozygous GRIN2D developmental and epileptic encephalopathy (DEE) patient (BGUi011-A) and from a healthy family relative (BGUi012-A).

A. Fattal-Valevski, K. Avraham, M. Rubinstein, 2021, Stem cell research.