Jeff L. Staudinger

发表

Disease, Drug Metabolism, and Transporter Interactions

Jeff L. Staudinger, 2013, Pharmaceutical Research.

Allopregnanolone is required for prepulse inhibition deficits induced by D1 dopamine receptor activation

J. Maguire, M. Bortolato, S. Fowler, 2019, Psychoneuroendocrinology.

Clustering of AMPA Receptors by the Synaptic PDZ Domain–Containing Protein PICK1

R. Huganir, Jun Xia, Xiaoqun Zhang, 1999, Neuron.

Regulation of drug transporter gene expression by nuclear receptors.

A. Parkinson, J. Staudinger, A. Madan, 2003, Drug metabolism and disposition: the biological fate of chemicals.

Cyclic AMP-dependent Protein Kinase Signaling Modulates Pregnane x Receptor Activity in a Species-specific Manner*

Kristin Lichti-Kaiser, J. Staudinger, Chenshu Xu, 2009, Journal of Biological Chemistry.

Guggulsterone Activates Multiple Nuclear Receptors and Induces CYP3A Gene Expression through the Pregnane X Receptor

B. Goodwin, J. Staudinger, Xunshan Ding, 2004, Journal of Pharmacology and Experimental Therapeutics.

Pregnane X receptor and natural products: beyond drug–drug interactions

J. Staudinger, Xunshan Ding, K. Lichti, 2006, Expert opinion on drug metabolism & toxicology.

Induction of Drug Metabolism by Forskolin: The Role of the Pregnane X Receptor and the Protein Kinase A Signal Transduction Pathway

J. Staudinger, Xunshan Ding, Jeff L. Staudinger, 2005, Journal of Pharmacology and Experimental Therapeutics.

SUMOylation and Ubiquitylation Circuitry Controls Pregnane X Receptor Biology in Hepatocytes

T. Williams, N. Galeva, J. Staudinger, 2015, Drug Metabolism and Disposition.

Regulation of Constitutive Androstane Receptor and Its Target Genes by Fasting, cAMP, Hepatocyte Nuclear Factor α, and the Coactivator Peroxisome Proliferator-activated Receptor γ Coactivator-1α*

F. Gonzalez, Insook Kim, J. Staudinger, 2006, Journal of Biological Chemistry.

CAR/PXR provide directives for Cyp3a41 gene regulation differently from Cyp3a11

D. Moore, H. Strobel, A. Kalsotra, 2004, The Pharmacogenomics Journal.

Nuclear-receptor–mediated regulation of drug– and bile-acid–transporter proteins in gut and liver

J. Staudinger, Sarah K. Woody, Wenqi Cui, 2013, Drug metabolism reviews.

Activated Pregnenolone X-Receptor Is a Target for Ketoconazole and Its Analogs

Hao Li, Denise G. Teotico, Hongwei Wang, 2007, Clinical Cancer Research.

The Traditional Chinese Herbal Remedy Tian Xian Activates Pregnane X Receptor and Induces CYP3A Gene Expression in Hepatocytes

Kristin Lichti-Kaiser, J. Staudinger, Jeff L. Staudinger, 2008, Drug Metabolism and Disposition.

The mycoestrogen zearalenone induces CYP3A through activation of the pregnane X receptor.

J. Staudinger, Xunshan Ding, K. Lichti, 2006, Toxicological sciences : an official journal of the Society of Toxicology.

Genomic characterization and regulation of CYP3a13: role of xenobiotics and nuclear receptors

H. Strobel, A. Kalsotra, P. Davies, 2003, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

NUCLEAR RECEPTOR, PREGNANE X RECEPTOR, IS REQUIRED FOR INDUCTION OF UDP-GLUCURONOSYLTRANSFERASES IN MOUSE LIVER BY PREGNENOLONE-16α-CARBONITRILE

C. Klaassen, Chuan Chen, J. Staudinger, 2003 .

Metabolism and toxicity of thioacetamide and thioacetamide S-oxide in rat hepatocytes.

R. Hanzlik, Y. Koen, Heather Hajovsky, 2012, Chemical research in toxicology.

PDZ Proteins Bind, Cluster, and Synaptically Colocalize with Eph Receptors and Their Ephrin Ligands

R. Huganir, D. Bredt, E. Olson, 1998, Neuron.

Functional Interaction between Monoamine Plasma Membrane Transporters and the Synaptic PDZ Domain–Containing Protein PICK1

A. Levey, M. Caron, W. Yao, 2001, Neuron.

PICK1: a perinuclear binding protein and substrate for protein kinase C isolated by the yeast two-hybrid system

J Staudinger, S. Elledge, E. Olson, 1995, The Journal of cell biology.

Phosphorylation Modulates the Coregulatory Protein Exchange of the Nuclear Receptor Pregnane X Receptor

J. Staudinger, Wenqi Cui, Xunan Shen, 2020, The Journal of Pharmacology and Experimental Therapeutics.

Cell signaling and nuclear receptors: new opportunities for molecular pharmaceuticals in liver disease.

J. Staudinger, K. Lichti, Jeff L. Staudinger, 2008, Molecular pharmaceutics.

Regulation of Peroxisome Proliferator-activated Receptor α-Induced Transactivation by the Nuclear Orphan Receptor TAK1/TR4*

A. Medvedev, A. Jetten, Alexander Medvedev, 1998, The Journal of Biological Chemistry.

The Molecular Interface Between the SUMO and Ubiquitin Systems.

J. Staudinger, Jeff L. Staudinger, 2017, Advances in experimental medicine and biology.

Liver protein targets of hepatotoxic 4-bromophenol metabolites.

Ke Liu, Robert P Hanzlik, Todd D Williams, 2012, Chemical research in toxicology.

Immunolocalization of PICK1 in the ascending auditory pathways of the adult rat

R. Harlan, Meredith M. Garcia, J. Staudinger, 2002, The Journal of comparative neurology.

Nuclear receptor-mediated regulation of carboxylesterase expression and activity

C. Klaassen, J. Staudinger, Chenshu Xu, 2010, Expert opinion on drug metabolism & toxicology.

Repression of PXR-mediated induction of hepatic CYP3A gene expression by protein kinase C.

J. Staudinger, Xunshan Ding, Jeff L. Staudinger, 2005, Biochemical pharmacology.

Pregnane X Receptor Modulates the Inflammatory Response in Primary Cultures of Hepatocytes

J. Staudinger, Sarah K. Woody, Wenqi Cui, 2015, Drug Metabolism and Disposition.

Regulation of Tissue-Specific Carboxylesterase Expression by Pregnane X Receptor and Constitutive Androstane Receptor

Xinkun Wang, J. Staudinger, Chenshu Xu, 2009, Drug Metabolism and Disposition.

The Ratio of Constitutive Androstane Receptor to Pregnane X Receptor Determines the Activity of Guggulsterone against the Cyp2b10 Promoter

J. Staudinger, Xunshan Ding, Jeff L. Staudinger, 2005, Journal of Pharmacology and Experimental Therapeutics.

Clinical applications of small molecule inhibitors of Pregnane X receptor

J. Staudinger, Jeff L. Staudinger, 2019, Molecular and Cellular Endocrinology.

Inhibition of drug metabolism by blocking the activation of nuclear receptors by ketoconazole

Denise G. Teotico, M. Redinbo, J. Locker, 2007, Oncogene.

Induction of rat organic anion transporting polypeptide 2 by pregnenolone-16alpha-carbonitrile is via interaction with pregnane X receptor.

C. Klaassen, G. Guo, J. Staudinger, 2002, Molecular pharmacology.

Post-translational modification of pregnane x receptor.

S. Mani, Arunima Biswas, J. Staudinger, 2011, Pharmacological research.

Nuclear receptor, pregname X receptor, is required for induction of UDP-glucuronosyltranferases in mouse liver by pregnenolone-16 alpha-carbonitrile.

C. Klaassen, Chuan Chen, J. Staudinger, 2003, Drug metabolism and disposition: the biological fate of chemicals.

Metabolism and toxicity of thioacetamide and thioacetamide S-oxide in rat hepatocytes.

R. Hanzlik, Y. Koen, Heather Hajovsky, 2012, Chemical research in toxicology.

A SUMO-acetyl switch in PXR biology.

T. Williams, N. Galeva, J. Staudinger, 2016, Biochimica et biophysica acta.

Pregnane X Receptor Modulates the Inflammatory Response in Primary Cultures of Hepatocytes

Sarah K. Woody, Wenqi Cui, Mengxi Sun, 2015, Drug Metabolism and Disposition.

Regulation of constitutive androstane receptor and its target genes by fasting, cAMP, hepatocyte nuclear factor alpha, and the coactivator peroxisome proliferator-activated receptor gamma coactivator-1alpha.

F. Gonzalez, Insook Kim, J. Staudinger, 2006, The Journal of biological chemistry.

Gender Dictates the Nuclear Receptor-Mediated Regulation of CYP3A44

D. Moore, H. Strobel, Wendong Huang, 2007, Drug Metabolism and Disposition.

Interaction between the glutamate transporter GLT1b and the synaptic PDZ domain protein PICK1

M. Brasch, Allison Paradise, U. Gether, 2007, The European journal of neuroscience.

Protein targets of thioacetamide metabolites in rat hepatocytes.

T. Williams, R. Hanzlik, Y. Koen, 2013, Chemical research in toxicology.

Activation of the JAK-STAT pathway is necessary for desensitization of 5-HT2A receptor-stimulated phospholipase C signalling by olanzapine, clozapine and MDL 100907.

R. Singh, J. Staudinger, N. Muma, 2009, The international journal of neuropsychopharmacology.

A Systematic Analysis of Predicted Phosphorylation Sites within the Human Pregnane X Receptor Protein

Kristin Lichti-Kaiser, J. Staudinger, Chenshu Xu, 2009, Journal of Pharmacology and Experimental Therapeutics.