J. Du

发表

SYNTHESES OF 2′,3′-DIDEOXY-D-C-NUCLEOSIDES FROM γ-LACTONE

C. K. Chu, Y. Xiang, Jinfa Du, 1996 .

Structure of Hepatitis C Virus Polymerase in Complex with Primer-Template RNA

M. Otto, A. Lam, M. Sofia, 2012, Journal of Virology.

Discovery of a β-d-2'-deoxy-2'-α-fluoro-2'-β-C-methyluridine nucleotide prodrug (PSI-7977) for the treatment of hepatitis C virus.

M. Otto, C. Espiritu, A. Lam, 2010, Journal of medicinal chemistry.

Use of 2'-spirocyclic ethers in HCV nucleoside design.

C. Espiritu, A. Lam, M. Sofia, 2014, Journal of medicinal chemistry.

Synthesis and anti-HCV activity of 3',4'-oxetane nucleosides.

M. Otto, M. Sofia, B. Ross, 2010, Bioorganic & medicinal chemistry letters.

Adenosine deaminase-like protein 1 (ADAL1): characterization and substrate specificity in the hydrolysis of N(6)- or O(6)-substituted purine or 2-aminopurine nucleoside monophosphates.

M. Sofia, R. Mosley, Haiying Bao, 2011, Journal of medicinal chemistry.

Structure-guided discovery of a novel, potent, and orally bioavailable 3,5-dimethylisoxazole aryl-benzimidazole BET bromodomain inhibitor.

R. Neve, R. Mackman, Xiaowu Chen, 2019, Bioorganic & medicinal chemistry.

Synthesis of β-Enantiomers of N4-Hydroxy-3′-Deoxy-Pyrimidine Nucleosides and Their Evaluation against Bovine Viral Diarrhoea Virus and Hepatitis C Virus in Cell Culture

L. Stuyver, R. Schinazi, H. Choo, 2004, Antiviral chemistry & chemotherapy.

Blockade of Tetrahydrobiopterin Synthesis Protects Neurons after Transient Forebrain Ischemia in Rat: A Novel Role for the Cofactor

B. Volpe, T. Joh, C. K. Chu, 1999, The Journal of Neuroscience.

A Randomized, Open‐Label, Controlled Clinical Trial of Azvudine Tablets in the Treatment of Mild and Common COVID‐19, a Pilot Study

Z. Ren, Zujiang Yu, Junbiao Chang, 2020, Advanced science.

Discovery of Dosimertinib, a Highly Potent, Selective, and Orally Efficacious Deuterated EGFR Targeting Clinical Candidate for the Treatment of Non-Small-Cell Lung Cancer.

Junbiao Chang, Yongfang Yao, Bin Yu, 2021, Journal of medicinal chemistry.

Metabolic Activation of the Anti-Hepatitis C Virus Nucleotide Prodrug PSI-352938

M. Otto, A. Lam, M. Sofia, 2012, Antimicrobial Agents and Chemotherapy.

Activity and the metabolic activation pathway of the potent and selective hepatitis C virus pronucleotide inhibitor PSI-353661.

M. Otto, C. Espiritu, A. Lam, 2011, Antiviral research.

Pharmacokinetics of 1-(2-fluoro-5-methyl-beta-L-arabinofuranosyl)uracil in woodchucks

C. K. Chu, B. Tennant, F. D. Boudinot, 1997, Antimicrobial agents and chemotherapy.

Syntheses of 2″,3″-Dideoxy-L-Glycero-Pentofuranosyl C-Nucleosides

C. K. Chu, Jinfa Du, Chang Soo Lee, 1996 .