J. O'neill

F. Perera, R. Albertini, J. O’Neill, 2002, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.

Treatment of Lesch–Nyhan disease with S-adenosylmethionine: Experience with five young Malaysians, including a girl

J. O’Neill, S. Balasubramaniam, J. Duley, 2014, Brain and Development.

The Spectrum of Mutations Causing HPRT Deficiency: An Update

H. Jinnah, J. O’Neill, W. Nyhan, 2004, Nucleosides, nucleotides & nucleic acids.

NUCLEOSIDES, NUCLEOTIDES & NUCLEIC ACIDS

J. O’Neill, W. Nyhan, H. Jinnah, 2004 .

In vivo somatic mutations in humans: measurement and analysis.

R. Albertini, J. Nicklas, J. O’Neill, 1990, Annual review of genetics.

Effect of pentachlorophenol on the activation of 2,6‐dinitrotoluene to genotoxic urinary metabolites in CD‐1 mice: A comparison of GI enzyme activities and urine mutagenicity

J. Creason, J. O’Neill, J. Dekker, 1991, Environmental and molecular mutagenesis.

HPRT mutations in vivo in human CD 34+ hematopoietic stem cells.

R. Albertini, J. Nicklas, J. O’Neill, 1999, Mutation research.

An analysis of in vivo hprt mutant frequency in circulating T-lymphocytes in the normal human population: a comparison of four datasets.

A. Tates, D. Beare, D. Robinson, 1994, Mutation research.

Refinement of a T-lymphocyte cloning assay to quantify the in vivo thioguanine-resistant mutant frequency in humans.

R. Albertini, J. Nicklas, J. O’Neill, 1987, Mutagenesis.

The spectrum of inherited mutations causing HPRT deficiency: 75 new cases and a review of 196 previously reported cases.

H. Jinnah, J. O’Neill, W. Nyhan, 2000, Mutation research.

Possible role of adenosine cyclic 3':5'-monophosphate phosphodiesterase in the morphological transformation of Chinese hamster ovary cells mediated by N6,O2-dibutyryl adenosine cyclic 3':5"-monophosphate.

J. O’Neill, C. Schröder, K. Kawashima, 1975, The Journal of biological chemistry.

Increased frequency of specific genomic deletions resulting from in vitro malathion exposure.

R. Albertini, J. Nicklas, J. O’Neill, 1996, Cancer research.

The effect of T-lymphocyte 'clonality' on the calculated hprt mutation frequency occurring in vivo in humans.

R. Branda, R. Albertini, J. Nicklas, 1994, Mutation research.

Factors influencing mutation at the hprt locus in T-lymphocytes: women treated for breast cancer.

R. Branda, R. Albertini, J. O’Neill, 1991, Cancer research.

Molecular analysis of in vivo hprt mutations in human T lymphocytes. V. Effects of total body irradiation secondary to radioimmunoglobulin therapy (RIT)

R. Albertini, J. Nicklas, T. Hunter, 1990, Mutagenesis.

Enumeration of 6‐thioguanine‐resistant T‐lymphocytes in the peripheral blood of nonhuman primates (cynomolgus monkeys)

R. Albertini, J. O’Neill, G. Hoffman, 1991, Environmental and molecular mutagenesis.

In vivo somatic mutation in the lymphocytes of Hodgkin's disease patients

H. Liber, K. Kelsey, J. O’Neill, 1991, Environmental and molecular mutagenesis.

Longitudinal study of the in vivo hprt mutant frequency in human T‐lymphocytes as determined by a cell cloning assay

R. Albertini, J. O’Neill, J. Booker, 1989, Environmental and molecular mutagenesis.

The induction of specific-locus mutations and sister-chromatid exchanges by 5-bromo- and 5-chloro-deoxyuridine.

J. O’Neill, R. J. Preston, M. Heartlein, 1982, Mutation research.

Induction of chromosomes aberrations, sister chromatid exchanges, and specific locus mutations in Chinese hamster ovary cells by 5-bromodeoxyuridine.

J. O’Neill, A. Hsie, J. S. San Sebastian, 1980, Cytogenetics and cell genetics.

Molecular description of three macro-deletions and an Alu-Alu recombination-mediated duplication in the HPRT gene in four patients with Lesch-Nyhan disease.

R. Branda, J. Nicklas, J. O’Neill, 2001, Mutation research.

Markers for carcinogenicity among butadiene-polymer workers in China.

R. Hayes, W. Bechtold, M. Dosemeci, 2001, Chemico-biological interactions.

Fine structure mapping of the hypoxanthine-guanine phosphoribosyltransferase (HPRT) gene region of the human X chromosome (Xq26).

R. Albertini, J. Nicklas, J. O’Neill, 1991, American journal of human genetics.

Analysis of human HPRT deletion mutations with X‐linked probes and pulsed field gel electrophoresis

R. Albertini, J. Nicklas, T. Hunter, 1991, Environmental and molecular mutagenesis.

Mammalian cell mutagenesis : the maturation of test systems

J. O’Neill, A. Hsie, V. Mcelheny, 1979 .

Measurement of chromosomal aberrations, sister chromatid exchange, hprt mutations, and DNA adducts in peripheral lymphocytes of human populations at increased risk for cancer

R. Branda, R. Albertini, J. Nicklas, 1993, Environmental health perspectives.

SCE induction is proportional to substitution in DNA for thymidine by CldU and BrdU.

J. O’Neill, R. J. Preston, M. Heartlein, 1983, Mutation research.

Factors influencing mutation at the hprt locus in T‐lymphocytes: Studies in normal women and women with benign and malignant breast masses

R. Branda, R. Albertini, J. O’Neill, 1992, Environmental and molecular mutagenesis.

Induction and Persistence of Chromosome Aberrations in Human Lymphocytes Exposed to Neutrons In vitro or In vivo: Implications of Findings in 'Retrospective' Biological Dosimetry

J. O’Neill, L. Littlefield, M. Maor, 2000 .

Quantitative Mammalian Cell Mutagenesis and Mutagen Screening: Study with Chinese Hamster Ovary Cells

J. O’Neill, A. Hsie, J. Sebastian, 1983 .

V(D)J recombinase-like activity mediates hprt gene deletion in human fetal T-lymphocytes.

J. Fuscoe, R. Albertini, J. Nicklas, 1991, Cancer research.

A quantitative assay of mutation induction at the hypoxanthine-guanine phosphoribosyl transferase locus in Chinese hamster ovary cells (CHO/HGPRT system): development and definition of the system.

J. O’Neill, A. Hsie, A W Hsie, 1977, Mutation research.

DNA damage, DNA repair, cell proliferation, and DNA replication: how do gene mutations result?

J. O’Neill, J. O'neill, 2000, Proceedings of the National Academy of Sciences of the United States of America.

Molecular analyses of a Lesch-Nyhan syndrome mutation (hprtMontreal) by use of T-lymphocyte cultures

T. Skopek, R. Albertini, J. Nicklas, 1990, Human Genetics.

Sequence-specific correction of genomic hypoxanthine-guanine phosphoribosyl transferase mutations in lymphoblasts by small fragment homologous replacement.

J. Nicklas, J. O’Neill, D. Gruenert, 2010, Oligonucleotides.

Gene mutations with characteristic deletions in cord blood T lymphocytes associated with passive maternal exposure to tobacco smoke

R. Albertini, J. O’Neill, P. Vacek, 1998, Nature Medicine.

Mutations that alter RNA splicing of the human HPRT gene: a review of the spectrum.

J. Nicklas, J. O’Neill, P. Rogan, 1998, Mutation research.

The effect of folate deficiency on the hprt mutational spectrum in Chinese hamster ovary cells treated with monofunctional alkylating agents.

R. Branda, J. Nicklas, J. O’Neill, 1999, Mutation research.

Action of cyclic nucleotide analogues in Chinese hamster ovary cells.

A. Li, J. O’Neill, A. Hsie, 1977, Biochimica et biophysica acta.

Correlation between changes in intracellular level of cyclic AMP, activation of cyclic AMP-dependent protein kinase, and the morphology of Chinese hamster ovary cells in culture.

A. Li, J. O’Neill, A. Hsie, 1977, Archives of biochemistry and biophysics.

The novel oral typhoid vaccine M01ZH09 is well tolerated and highly immunogenic in 2 vaccine presentations.

J. O’Neill, B. Kirkpatrick, Z. Hindle, 2005, The Journal of infectious diseases.

Serum mannose-binding lectin deficiency is associated with cryptosporidiosis in young Haitian children.

J. O’Neill, J. Pape, C. Sears, 2006, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

The use of Chinese hamster ovary cells to quantify specific locus mutation and to determine mutagenicity of chemicals. A report of the gene-tox program.

J. O’Neill, D. Casciano, A. Hsie, 1981, Mutation research.

A guide for the performance of the Chinese hamster ovary cell/hypoxanthine-guanine phosphoribosyl transferase gene mutation assay.

A. Li, W. Choy, J. O’Neill, 1987, Mutation research.

Carcinogen-DNA adducts and gene mutation in foundry workers with low-level exposure to polycyclic aromatic hydrocarbons.

F. Perera, W. Tsai, K. Hemminki, 1994, Carcinogenesis.

Development of long PCR techniques to analyze deletion mutations of the human hprt gene.

B. Van Houten, J. Nicklas, J. O’Neill, 1998, Mutation research.

Genotoxicity of 3'-azido-3'-deoxythymidine in the human lymphoblastoid cell line, TK6: relationships between DNA incorporation, mutant frequency, and spectrum of deletion mutations in HPRT.

J. O’Neill, M. Poirier, V. Walker, 1999, Mutation research.

Plasma and cellular markers of 3′‐azido‐3′‐dideoxythymidine (AZT) metabolism as indicators of DNA damage in cord blood mononuclear cells from infants receiving prepartum NRTIs

J. O’Neill, W. Bigbee, M. Poirier, 2007, Environmental and molecular mutagenesis.

Genotoxicity assessed by the comet and GPA assays following in vitro exposure of human lymphoblastoid cells (H9) or perinatal exposure of mother–child pairs to AZT or AZT‐3TC

R. Ness, J. O’Neill, W. Bigbee, 2007, Environmental and molecular mutagenesis.

Phenotypic expression time of mutagen-induced 6-thioguanine resistance in Chinese hamster ovary cells (CHO/HGPRT system).

J. O’Neill, A. Hsie, J. O'neill, 1979, Mutation research.

Induction and expression of mutations in mammalian cells in the absence of DNA synthesis and cell division.

J. O’Neill, J. O'neill, 1982, Mutation research.

Molecular analysis of mutations at the HPRT and TK loci of human lymphoblastoid cells after combined treatments with 3′‐azido‐3′‐deoxythymidine and 2′,3′‐dideoxyinosine †

J. O’Neill, V. Walker, Q. Meng, 2002, Environmental and molecular mutagenesis.

Mutagenicity, cytotoxicity, and DNA binding of platinum(II)-chloroammines in Chinese hamster ovary cells.

J. O’Neill, J. Hoeschele, A. Hsie, 1980, Cancer research.

Mitochondrial damage and DNA depletion in cord blood and umbilical cord from infants exposed in utero to Combivir

K. Nagashima, J. O’Neill, S. Seilkop, 2004, AIDS.

Quantification and analysis of reverse mutations at the hgprt locus in Chinese hamster ovary cells.

J. Fuscoe, J. O’Neill, A. Hsie, 1982, Mutation research.

The cytotoxic and mutagenic effects of 5-bromodeoxyuridine-plus-black-light treatment in cultured mammalian cells.

J. O’Neill, L. A. Lynn, J. O'neill, 1982, Mutation research.

Phenotypic expression time of mutagen-induced 6-thioguanine resistance in Chinese hamster ovary cells (CHO/HGPRT system): expression in division-arrested cell cultures.

J. O’Neill, A. Hsie, R. Machanoff, 1982, Environmental mutagenesis.

Hudrolysis of butyryl derivatives of adenosine cyclic 3':5'-monophosphate by Chinese hamster ovary cell extracts and characterization fo the products.

J. O’Neill, C. Schröder, C. Schröder, 1975, The Journal of biological chemistry.

The cell cycle specificity of the morphological conversion of chinese hamster ovary cells by N6, O2'-dibutyryl cyclic adenosine 3',5'-phosphate.

J. O’Neill, A. Hsie, C. Schröder, 1976, Experimental cell research.

Melanin photosensitizes ultraviolet light (uvc) dna damage in pigmented cells

J. O’Neill, C. Huselton, H. Hill, 1990, Environmental and molecular mutagenesis.

The effect of dietary folic acid deficiency on the cytotoxic and mutagenic responses to methyl methanesulfonate in wild-type and in 3-methyladenine DNA glycosylase-deficient Aag null mice.

R. Branda, J. Nicklas, J. O’Neill, 2007, Mutation research.

Cytotoxicity and mutagenicity of alkylating agents in cultured mammalian cells (CHO/HGPRT system): mutagen treatment in the presence or absence of serum.

J. O’Neill, A. Hsie, R. L. Schenley, 1979, Mutation research.

Relationship between DNA alkylation and specific-locus mutation induction by N-methyl- and N-ethyl-N-nitrosourea in cultured Chinese hamster ovary cells (CHO/HGPRT system).

J. O’Neill, H. Thielmann, A. Hsie, 1979, Chemico-biological interactions.

Metabolic cooperation in the selection of thioguanine‐resistant mutants does not occur with the human B‐lymphoblastoid cell TK6

R. Gundel, J. O'neill, 1997, Environmental and molecular mutagenesis.

Effect of selection cell density on the recovery of mutagen-induced 6-thioguanine-resistant cells (CHO/HGPRT system).

K. Bowman, J. O'neill, 1982, Environmental Mutagenesis.

X-ray induction of 6-thioguanine-resistant mutants in division arrested, G0/G1 phase Chinese hamster ovary cells.

J. O’Neill, K. B. Flint, J. O'neill, 1985, Mutation research.

Induction of temperature-sensitive 6-thioguanine-resistant mutants as a measure of base-pair substitution mutations in Chinese hamster ovary cells.

J. O'neill, 1984, Mutation research.

Chemical mutagenesis of mammalian cells can be quantified

J. O’Neill, A. Hsie, J. O'neill, 1977, Nature.

Mutation carrier testing in Lesch-Nyhan syndrome families: HPRT mutant frequency and mutation analysis with peripheral blood T lymphocytes.

J. O’Neill, J. O'neill, 2004, Genetic testing.

Germinal HPRT splice donor site mutation results in multiple RNA splicing products in T-lymphocyte cultures

T. Skopek, R. Albertini, J. O’Neill, 1996, Somatic cell and molecular genetics.

Suggestions concerning the relationship between mutant frequency and mutation rate at the hprt locus in human peripheral T-lymphocytes.

J. O’Neill, M. Green, J. Cole, 1995, Mutation research.

Sister-chromatid exchanges and gene mutations are induced by the replication of 5-bromo- and 5-chloro-deoxyuridine substituted DNA.

J. O’Neill, R. J. Preston, M. Heartlein, 1983, Mutation research.

Detection of DNA damage and repair by alkaline elution using human lymphocytes.

J. O’Neill, S. Robison, J. S. Munzer, 1988, Mutation research.

HPRT deficiency in a two-month-old child presenting acute renal failure and gout with a new deletion of two bases in exon 3 of the HPRT gene.

J. O’Neill, R. O. Escárcega, R. Vazquez, 2007, Archives of medical research.

Mutagenicity and cytotoxicity of nineteen heterocyclic mustards (ICR compounds) in cultured mammalian cells.

J. Fuscoe, J. O’Neill, A. Hsie, 1979, Cancer research.

Introduction to the U.S. environmental protection agency's genetic risk assessment on ethylene oxide

V. Dellarco, W. Farland, J. O'neill, 1990, Environmental and Molecular Mutagenesis.

Quantitative analysis of cytotoxicity and mutagenicity of benzo[a]pyrene in mammalian cells (CHO/HGPRT system).

J. O’Neill, A. Hsie, R. Machanoff, 1981, Chemico-biological interactions.

A quantitative assay of mutation induction at the hypoxanthine-guanine phosphoribosyl transferase locus in Chinese hamster ovary cells (CHO/HGPRT system): utilization with a variety of mutagenic agents.

J. O’Neill, A. Hsie, R. Machanoff, 1977, Mutation research.

Mutagenicity of alkaline constituents of a coal-liquified crude oil in mammalian cells.

J. O’Neill, A. Hsie, J. Epler, 1980, Mutation research.

Mutagenicity of heterocyclic nitrogen mustards (ICR compounds) in cultured mammalian cells.

J. Fuscoe, J. O’Neill, A. Hsie, 1978, Cancer research.

Fluctuation analyses of spontaneous mutations to 6-thioguanine resistance in Chinese hamster ovary cells in culture.

J. O’Neill, A. Hsie, P. Brimer, 1981, Mutation research.

High frequency in vivo loss of heterozygosity is primarily a consequence of mitotic recombination.

J. Tischfield, R. Albertini, J. O’Neill, 1997, Cancer research.

Southern-blot analyses of human T-lymphocyte mutants induced in vitro by γ-irradiation

R. Albertini, J. Nicklas, J. O’Neill, 1990 .

Genetic instability in human T-lymphocytes.

T. Skopek, R. Albertini, J. Nicklas, 1998, Mutation research.

In vivo ionizing irradiations produce deletions in the hprt gene of human T-lymphocytes.

R. Albertini, J. Nicklas, J. O’Neill, 1991, Mutation research.

In vitro induction, expression and selection of thioguanine-resistant mutants with human T-lymphocytes.

R. Albertini, J. O’Neill, L. Sullivan, 1990, Mutation research.

Molecular analyses of in vivo hprt mutations in human T-lymphocytes. I. Studies of low frequency 'spontaneous' mutants by Southern blots.

R. Albertini, J. Nicklas, J. O’Neill, 1987, Mutagenesis.

Molecular analyses of in vivo hypoxanthine-guanine phosphoribosyltransferase mutations in human T-lymphocytes: II. Demonstration of a clonal amplification of hprt mutant T-lymphocytes in vivo.

R. Albertini, J. Nicklas, J. O’Neill, 1988, Environmental and molecular mutagenesis.

Use of T-cell receptor gene probes to quantify the in vivo hprt mutations in human T-lymphocytes.

R. Albertini, J. Nicklas, J. O’Neill, 1986, Mutation research.

Mutagenicity monitoring in humans by autoradiographic assay for mutant T lymphocytes.

R. Albertini, J. O’Neill, J. Stewart, 1988, Mutation research.

Analysis of point mutations in the hprt gene of cancer patients treated with radioimmunoglobulin therapy

R. Albertini, J. Nicklas, J. O’Neill, 1995, Environmental and molecular mutagenesis.

Alterations of the hprt gene in human in vivo-derived 6-thioguanine-resistant T lymphocytes

R. Albertini, J. Nicklas, J. O’Neill, 1985, Nature.

Lesch-Nyhan disease in a female with a clinically normal monozygotic twin.

D. Schretlen, H. Jinnah, J. O’Neill, 2005, Molecular genetics and metabolism.

Somatic mutant frequency at the HPRT locus in children associated with a pediatric cancer cluster linked to exposure to two superfund sites

J. O’Neill, P. Vacek, T. Messier, 2005, Environmental and molecular mutagenesis.

Induction of chromosome aberrations and specific locus mutation but not sister chromatid exchanges in Chinese hamster ovary cells by neocarzinostatin.

J. O’Neill, R. J. Preston, W. Au, 1984, Teratogenesis, carcinogenesis, and mutagenesis.

DNA sequence analysis of in vivo hprt mutation in human T lymphocytes.

T. Skopek, R. Albertini, J. Nicklas, 1990, Mutagenesis.

hprt mutations in vivo in human T-lymphocytes: frequencies, spectra and clonality.

T. Skopek, R. Albertini, J. Nicklas, 1990, Progress in clinical and biological research.