A. Wang

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Solution structure of a DNA duplex containing a cis-diammineplatinum(II) 1,3-d(GTG) intrastrand cross-link, a major adduct in cells treated with the anticancer drug carboplatin.

A. Wang, J. Reedijk, C. Bauer, 1999, Biochemistry.

X-ray structure of the major adduct of the anticancer drug cisplatin with DNA: cis-[Pt(NH3)2(d(pGpG))].

A. Wang, S. Lippard, D. Gibson, 1985, Science.

Minor groove binding of SN6999 to an alkylated DNA: molecular structure of d(CGC[e6G]AATTCGCG)-SN6999 complex.

W. Denny, A. Wang, Y. Gao, 1993, Biochemistry.

Structural polymorphism and raman conformation markers of cyclic deoxytriadenylic acid.

A. Wang, J. Benevides, Y. Gao, 1998, Nucleic acids research.

Molecular structure of antitumor drug steffimycin and modelling of its binding to DNA.

A. Wang, Y. Gao, Y. Liaw, 1991, Journal of biomolecular structure & dynamics.

Molecular structure of the complex formed between the anticancer drug cisplatin and d(pGpG): C222(1) crystal form.

A. Wang, S. Lippard, D. Gibson, 1990, Journal of biomolecular structure & dynamics.

Additional antitumor ecteinascidins from a Caribbean tunicate: crystal structures and activities in vivo.

R. Sakai, A. Wang, K. Rinehart, 1992, Proceedings of the National Academy of Sciences of the United States of America.

Molecular and crystal structures of ecteinascidins: potent antitumor compounds from the Caribbean tunicate Ecteinascidia turbinata.

R. Sakai, A. Wang, K. Rinehart, 1993, Journal of biomolecular structure & dynamics.

Biochemical and structural studies of the tetragonal crystalline modification of the Escherichia coli elongation factor Tu.

F. Jurnak, A. Rich, A. McPherson, 1980, The Journal of biological chemistry.

Structure at 2.3 A resolution of the gene 5 product of bacteriophage fd: a DNA unwinding protein.

F. Jurnak, A. Rich, A. McPherson, 1979, Journal of molecular biology.

Molecular structure of the octamer d(G-G-C-C-G-G-C-C): modified A-DNA.

A. Rich, A. Wang, S. Fujii, 2011, Proceedings of the National Academy of Sciences of the United States of America.

A one- and two-dimensional NMR study of the B to Z transition of (m5dC-dG)3 in methanolic solution.

A. Rich, G. A. van der Marel, J. Feigon, 1984, Nucleic acids research.

Molecular structure of (m5 dC-dG)3: the role of the methyl group on 5-methyl cytosine in stabilizing Z-DNA.

A. Rich, G. A. van der Marel, A. Wang, 1982, Nucleic acids research.

The tetramer d(CpGpCpG) crystallizes as a left-handed double helix.

J. L. Crawford, J L Crawford, A. Rich, 1980, Proceedings of the National Academy of Sciences of the United States of America.

Atomic resolution analysis of a 2:1 complex of CpG and acridine orange.

A. Rich, G. Quigley, A. Wang, 1979, Nucleic acids research.

Yeast phenylalanine transfer RNA: atomic coordinates and torsion angles.

N. Seeman, A. Rich, F. L. Suddath, 1975, Nucleic acids research.

Structures of cobalt(III)-pepleomycin and cobalt(III)-deglycopepleomycin (green forms) determined by NMR studies.

A. Wang, H. Sugiyama, J. Cáceres-Cortés, 1997, European journal of biochemistry.

The chemistry and biology of left-handed Z-DNA.

A. Rich, A. Nordheim, A. Wang, 1984, Annual review of biochemistry.

Interactions between an anthracycline antibiotic and DNA: molecular structure of daunomycin complexed to d(CpGpTpApCpG) at 1.2-A resolution.

A. Rich, G. Quigley, A. Wang, 1987, Biochemistry.

The general structure of transfer RNA molecules.

N. Seeman, A. Rich, S. Kim, 1974, Proceedings of the National Academy of Sciences of the United States of America.

Structural studies of atom-specific anticancer drugs acting on DNA.

A. Wang, X. Yang, A. Wang, 1999, Pharmacology & therapeutics.

High-resolution A-DNA crystal structures of d(AGGGGCCCCT). An A-DNA model of poly(dG) x poly(dC).

A. Wang, A. H. Wang, H. Robinson, 1999, European journal of biochemistry.

Structural studies of a stable parallel-stranded DNA duplex incorporating isoguanine:cytosine and isocytosine:guanine basepairs by nuclear magnetic resonance spectroscopy.

A. Wang, S. Ikeda, H. Sugiyama, 1998, Biophysical journal.

Structural effects of the C2-methylhypoxanthine:cytosine base pair in B-DNA: A combined NMR and X-ray diffraction study of d(CGC[m2I]AATTCGCG).

G. A. van der Marel, A. Wang, H. Robinson, 1993, Biochemistry.

Molecular structure of cyclic diguanylic acid at 1 A resolution of two crystal forms: self-association, interactions with metal ion/planar dyes and modeling studies.

A. Wang, Y. Guan, H. Robinson, 1993, Journal of biomolecular structure & dynamics.

Structure and stereochemistry of cyclobutatusin, a diterpenoid containing a four-membered ring.

D. Lavie, I. Paul, E. Levy, 1974, Journal of the American Chemical Society.

Structural studies of interactions between anticancer platinum drugs and DNA.

A. Wang, D. Yang, A. Wang, 1996, Progress in biophysics and molecular biology.

5-Fluorodeoxyuridine as an alternative to the synthesis of mixed hybridization probes for the detection of specific gene sequences.

A. Wang, L. Ercolani, J. Habener, 1988, Proceedings of the National Academy of Sciences of the United States of America.

Formaldehyde cross-links daunorubicin and DNA efficiently: HPLC and X-ray diffraction studies.

A. Wang, Y. Gao, Y. Liaw, 1992, Biochemistry.

The molecular structure of a DNA-triostin A complex.

A. Rich, G. A. van der Marel, G. Quigley, 1984, Science.

The structure of aspartyl dipeptidase reveals a unique fold with a Ser-His-Glu catalytic triad.

A. Wang, C. Miller, K. Håkansson, 2000, Proceedings of the National Academy of Sciences of the United States of America.

Structure of an antigelling agent, l‐phenylalanyl‐glycyl‐glycyl‐d‐phenylalanine trihydrate

S. Burley, S. Fujii, A. Wang, 1987 .

Structure of an antisickling agent, N‐phenylacetyl‐l‐phenylalanine

S. Burley, A. Wang, 1987 .

Antigelling and antisickling bisphenyl oligopeptides and peptide analogues have similar structural features.

A. Rich, S. Burley, J. Votano, 1987, Biochemistry.

Local mobility of nucleic acids as determined from crystallographic data. II. Z-form DNA.

A. Rich, S. Holbrook, S. Kim, 1984, Journal of molecular biology.

Chemistry of the streptovaricins. IX. X-ray crystallographic structure of a streptovaricin C derivative.

K. Rinehart, F. J. Antosz, I. Paul, 1971, Journal of the American Chemical Society.

NMR studies on the binding of antitumor drug nogalamycin to DNA hexamer d(CGTACG).

G. A. van der Marel, A. Wang, H. Robinson, 1990, Nucleic acids research.

Structure by NMR of antitumor drugs aclacinomycin A and B complexed to d(CGTACG).

A. Wang, D. Yang, A. Wang, 1994, Biochemistry.

Distamycin A modulates the sequence specificity of DNA alkylation by duocarmycin A.

A. Wang, H. Sugiyama, I. Saito, 1996, Proceedings of the National Academy of Sciences of the United States of America.

The high salt form of poly(dG-dC).poly(dG-dC) is left-handed Z-DNA: Raman spectra of crystals and solutions.

A. Rich, A. Wang, T. J. Thamann, 1981, Nucleic acids research.

Covalent modification of guanine bases in double-stranded DNA. The 1.2-A Z-DNA structure of d(CGCGCG) in the presence of CuCl2.

A. Wang, P. S. Ho, B. Geierstanger, 1992, The Journal of biological chemistry.

An assessment of the Z-DNA forming potential of alternating dA-dT stretches in supercoiled plasmids.

R. J. Kelleher, A. Rich, J. Feigon, 1986, Biochemistry.

Influence of counter-ions on the crystal structures of DNA decamers: binding of [Co(NH3)6]3+ and Ba2+ to A-DNA.

A. Wang, H. Robinson, Y. Gao, 1996, Biophysical journal.

The molecular structure of the left-handed Z-DNA double helix at 1.0-A atomic resolution. Geometry, conformation, and ionic interactions of d(CGCGCG).

A. Rich, G. Quigley, A. Wang, 1989, The Journal of biological chemistry.

Binding of the antitumor drug nogalamycin to bulged DNA structures.

J. Cáceres-Cortés, A. Wang, 1996, Biochemistry.

Binding of the modified daunorubicin WP401 adjacent to a T-G base pair induces the reverse Watson-Crick conformation: crystal structures of the WP401-TGGCCG and WP401-CGG[br5C]CG complexes.

Y. Gao, W. Priebe, R. Dutta, 1998, Nucleic acids research.

Binding of a Hoechst dye to d(CGCGATATCGCG) and its influence on the conformation of the DNA fragment.

A. Rich, G. A. van der Marel, M. A. Carrondo, 1989, Biochemistry.

Neomycin, spermine and hexaamminecobalt (III) share common structural motifs in converting B- to A-DNA.

A. Wang, H. Robinson, A. Wang, 1996, Nucleic acids research.

Low‐frequency dynamics and Raman scattering of crystals, of B‐, A‐, and Z‐DNA, and fibers of C‐DNA

A. Wang, G. Thomas, O. P. Lamba, 1989, Biopolymers.

Structural basis of electron transfer modulation in the purple CuA center.

A. Wang, H. Robinson, Y. Gao, 1999, Biochemistry.

Structure of the gene V protein of bacteriophage f1 determined by multiwavelength x-ray diffraction on the selenomethionyl protein.

T C Terwilliger, R M Sweet, H. Bellamy, 1993, Proceedings of the National Academy of Sciences of the United States of America.

Effect of the G.T mismatch on backbone and sugar conformations of Z-DNA and B-DNA: analysis by Raman spectroscopy of crystal and solution structures of d(CGCGTG) and d(CGCGCG).

G. A. van der Marel, A. Wang, G. Thomas, 1989, Biochemistry.

Crystal and solution structures of the B-DNA dodecamer d(CGCAAATTTGCG) probed by Raman spectroscopy: heterogeneity in the crystal structure does not persist in the solution structure.

G. A. van der Marel, A. Wang, G. Thomas, 1988, Biochemistry.

Laser Raman Spectroscopy of Nucleic Acids

A. Wang, G. Thomas, A. Wang, 1988 .

Raman spectra of single crystals of r(GCG)d(CGC) and d(CCCCGGGG) as models for A DNA, their structure transitions in aqueous solution, and comparison with double-helical poly(dG).poly(dC).

A. Rich, G. A. van der Marel, A. Wang, 1986, Biochemistry.

The Raman spectra of left-handed DNA oligomers incorporating adenine-thymine base pairs+.

A. Rich, G. A. van der Marel, A. Wang, 1984, Nucleic acids research.

Structural basis for stabilization of Z-DNA by cobalt hexaammine and magnesium cations.

A. Rich, G. A. van der Marel, G. Quigley, 1985, Biochemistry.

Monofunctional platinum amine complexes destabilize DNA significantly.

A. Wang, D. Gibson, C. Bauer, 1998, European journal of biochemistry.

Simultaneous incorporations of two anticancer drugs into DNA. The structures of formaldehyde-cross-linked adducts of daunorubicin-d(CG(araC)GCG) and doxorubicin-d(CA(araC)GTG) complexes at high resolution.

G. A. van der Marel, H. Zhang, Y. Gao, 1993, The Journal of biological chemistry.

Hexahydrated magnesium ions bind in the deep major groove and at the outer mouth of A-form nucleic acid duplexes.

A. Joachimiak, H. Robinson, R. Sanishvili, 2000, Nucleic acids research.

Crystal structure of Z-DNA without an alternating purine-pyrimidine sequence.

A. Rich, G. A. van der Marel, A. Wang, 1985, Proceedings of the National Academy of Sciences of the United States of America.

A crystallographic investigation of citrate synthase from pig and chicken heart muscle.

A. Rich, A. Wang, M. L. Sherman, 1978, Biochemical and biophysical research communications.

The structure of a DNA unwinding protein and its complexes with oligodeoxynucleotides by x-ray diffraction.

F. Jurnak, A. Rich, A. McPherson, 1980, Biophysical journal.

Crystal and molecular structure of 3,N4-ethenocytidine hydrochloride. A study of the dimensions and molecular interactions of the fluorescent epsilon-cytidine system.

J. Barrio, I. Paul, A. Wang, 1976, Journal of the American Chemical Society.

Demonstration of Z-d(5BrCGAT5BrCG) and B-d(CGCGATCGCG) form crystal structures in DNA-cobalt hexammine complexes by Kr 647.1 nm excitation of Raman spectra.

J. Benevides, G. Thomas, A. Wang, 1993, Nucleic acids research.

Molecular structure of an A-DNA decamer d(ACCGGCCGGT).

A. Rich, G. A. van der Marel, G. Quigley, 1989, European journal of biochemistry.

The crystal structure of d(CCCCGGGG): a new A-form variant with an extended backbone conformation.

A. Rich, A. Wang, Z. Shakked, 1987, Journal of biomolecular structure & dynamics.

Structure of 11-deoxydaunomycin bound to DNA containing a phosphorothioate.

A. Rich, G. A. van der Marel, G. Quigley, 1990, Journal of molecular biology.

Interactions Between Antitumor Drugs and DNA

A. Wang, A. Wang, 1987 .

Binding of the antitumor drug nogalamycin and its derivatives to DNA: structural comparison.

A. Wang, H. Robinson, Y. Gao, 1991, Biochemistry.

Crystallographic analysis of a novel complex of actinomycin D bound to the DNA decamer CGATCGATCG.

A. Joachimiak, A. Wang, H. Robinson, 2001, Biochemistry.

Molecular structure of nicked DNA: a substrate for DNA repair enzymes.

A. Rich, G. A. van der Marel, A. Wang, 1990, Proceedings of the National Academy of Sciences of the United States of America.