Hongfeng Ruan

发表

Pyroptosis and Intervertebral Disc Degeneration: Mechanistic Insights and Therapeutic Implications

Huan Luo, H. Ruan, Cheng-liang Wu, 2022, Journal of inflammation research.

Cantharidin inhibits osteosarcoma proliferation and metastasis by directly targeting miR-214-3p/DKK3 axis to inactivate β-catenin nuclear translocation and LEF1 translation

Xiaobo Wang, Xiaoping Ma, Junli Chang, 2021, International journal of biological sciences.

Network Pharmacology and Experimental Validation to Reveal the Pharmacological Mechanisms of Liuwei Dihuang Decoction Against Intervertebral Disc Degeneration

Huihao Zhang, Huan Luo, Hongting Jin, 2021, Drug design, development and therapy.

Aberrant spinal mechanical loading stress triggers intervertebral disc degeneration by inducing pyroptosis and nerve ingrowth

Di Chen, Huihao Zhang, Huan Luo, 2021, Scientific reports.

Loganin ameliorates cartilage degeneration and osteoarthritis development in an osteoarthritis mouse model through inhibition of NF-κB activity and pyroptosis in chondrocytes.

Huan Yu, Hongting Jin, P. Tong, 2020, Journal of ethnopharmacology.

Hedgehog signaling through GLI1 and GLI2 is required for epithelial-mesenchymal transition in human trophoblasts.

Haibin Zhu, Ximei Wu, Liu Mei, 2015, Biochimica et biophysica acta.

Emerging Roles of Platelets in Allergic Asthma

H. Ruan, M. Yue, Mengjiao Hu, 2022, Frontiers in Immunology.

Validation of NEDD8-conjugating enzyme UBC12 as a new therapeutic target in lung cancer

Guoan Chen, Xiaojun Liu, L. Jia, 2019, EBioMedicine.

p21-activated kinase 1 determines stem-like phenotype and sunitinib resistance via NF-κB/IL-6 activation in renal cell carcinoma

Y. Pan, Haibin Zhu, Ximei Wu, 2015, Cell Death and Disease.

Morroniside attenuates apoptosis and pyroptosis of chondrocytes and ameliorates osteoarthritic development by inhibiting NF-κB signaling.

Huan Luo, Di Chen, Huan Yu, 2020, Journal of ethnopharmacology.

Whole-body Vibration Attenuates Pyroptosis-Mediated Inflammation but Accelerates Progression of Intervertebral Disc Degeneration

Huan Luo, Huan Yu, Di Chen, 2020 .

Morroniside attenuates nucleus pulposus cell senescence to alleviate intervertebral disc degeneration via inhibiting ROS-Hippo-p53 pathway

Huihao Zhang, W. Ji, Huan Luo, 2022, Frontiers in Pharmacology.

Study on the mechanism of cadmium chloride pollution accelerating skin tissue metabolism disorder, aging and inhibiting hair regeneration

Renfu Quan, H. Ruan, Yi Dong, 2022, Frontiers in Public Health.

Biomechanical, histologic, and molecular characteristics of graft-tunnel healing in a murine modified ACL reconstruction model

Huan Luo, Taotao Xu, Huan Yu, 2020, Journal of orthopaedic translation.

Smoothened-independent activation of hedgehog signaling by rearranged during transfection promotes neuroblastoma cell proliferation and tumor growth.

Ximei Wu, Huan Luo, Xing Ji, 2016, Biochimica et biophysica acta.

Intratibial Osteosarcoma Growth and Pulmonary Metastasis Inhibition by HIPPO Signaling Pathway-Induced Photodynamic Therapy

Wenyi Wang, Penghui Zhao, Junli Chang, 2023, Materials & Design.

AR/PCC herb pair inhibits osteoblast pyroptosis to alleviate diabetes-related osteoporosis by activating Nrf2/Keap1 pathway.

Huan Luo, Nani Wang, Yu-Zhong Du, 2023, Journal of cellular and molecular medicine.

Glioma-associated Oncogene 2 Is Essential for Trophoblastic Fusion by Forming a Transcriptional Complex with Glial Cell Missing-a*

Musaddique Hussain, Ximei Wu, Chao Tang, 2016, The Journal of Biological Chemistry.

Selenium Regulates Gene Expression of Selenoprotein W in Chicken Skeletal Muscle System

Shiwen Xu, Shu Li, Ziwei Zhang, 2011, Biological Trace Element Research.

Morroniside ameliorates inflammatory skeletal muscle atrophy via inhibiting canonical and non-canonical NF-κB and regulating protein synthesis/degradation

H. Zheng, J. Tao, Hongting Jin, 2022, Frontiers in Pharmacology.

Ascorbic acid uptaken by sodium-dependent vitamin C transporter 2 induces βhCG expression through Sp1 and TFAP2A transcription factors in human choriocarcinoma cells.

Haibin Zhu, Ximei Wu, Lihua Chen, 2012, The Journal of clinical endocrinology and metabolism.

Dehydroascorbic acid taken up by glucose transporters stimulates estradiol production through inhibition of JNK/c-Jun/AP1 signaling in JAR cells.

Haibin Zhu, Ximei Wu, Chao Tang, 2014, Molecular human reproduction.

Down-Regulated microRNA-34a Expression as a Prognostic Marker for Poor Osteosarcoma in Mice: A Systematic Review and Meta-Analysis

Wenyi Wang, Xiaobo Wang, Junli Chang, 2018, Journal of Cancer.

Therapeutic effects of whole-body vibration on fracture healing in ovariectomized rats: a systematic review and meta-analysis.

Xue-jun Cui, M. Yao, H. Ruan, 2019, Menopause.

Mechanisms of action and synergetic formulas of plant-based natural compounds from traditional Chinese medicine for managing osteoporosis: a literature review

Huan Luo, Lingfeng Zeng, Chengcong Zhou, 2023, Frontiers in medicine.

N-Butanol Extract of Modified You-Gui-Yin Attenuates Osteoclastogenesis and Ameliorates Osteoporosis by Inhibiting RANKL-Mediated NF-κB Signaling

Mancang Gu, Taotao Xu, Hongting Jin, 2022, Frontiers in Endocrinology.

Hedgehog signaling stimulates the conversion of cholesterol to steroids.

Haibin Zhu, Ximei Wu, Huan Luo, 2015, Cellular signalling.

Administration of erythropoietin prevents bone loss in osteonecrosis of the femoral head in mice

Shanxing Zhang, Taotao Xu, Qiang Mao, 2017, Molecular medicine reports.

DDDT_A_338439 4911..4924

Huihao Zhang, Huan Luo, H. Ruan, 2021 .

Glioma-associated Oncogene 2 Is Essential for Trophoblastic Fusion by Forming a Transcriptional Complex with Glial Cell Missing-a*

Musaddique Hussain, Ximei Wu, Chao Tang, 2016, The Journal of Biological Chemistry.

Bushenhuoxue formula accelerates fracture healing via upregulation of TGF-β/Smad2 signaling in mesenchymal progenitor cells.

Taotao Xu, Qinwen Ge, Zhenyu Shi, 2020, Phytomedicine : international journal of phytotherapy and phytopharmacology.

Inhibition of Caspase-1-mediated pyroptosis promotes osteogenic differentiation, offering a therapeutic target for osteoporosis.

Huan Luo, P. Tong, Fang-da Fu, 2023, International immunopharmacology.

Integration of Network Pharmacology and Experimental Validation to Explore the Pharmacological Mechanisms of Zhuanggu Busui Formula Against Osteoporosis

Huihao Zhang, Huan Luo, Hongting Jin, 2022, Frontiers in Endocrinology.

Electroacupuncture suppresses neuronal ferroptosis to relieve chronic neuropathic pain

Lei Xie, Zhen Gu, Hongfeng Ruan, 2024, Journal of cellular and molecular medicine.

Atrazine exposure promotes cardiomyocyte pyroptosis to exacerbate cardiotoxicity by activating NF-κB pathway.

Fang-da Fu, Sai Yao, Hongfeng Ruan, 2024, The Science of the total environment.

α‐Solanine attenuates chondrocyte pyroptosis to improve osteoarthritis via suppressing NF‐κB pathway

Fang-da Fu, Sai Yao, Weibin Du, 2024, Journal of cellular and molecular medicine.

Significance of pyroptosis-related gene in the diagnosis and classification of rheumatoid arthritis

Jun Yu Li, Jian Li, Jinxi Zhang, 2023, Frontiers in Endocrinology.

Comparative intra-articular gene transfer of seven adeno-associated virus serotypes reveals that AAV2 mediates the most efficient transduction to mouse arthritic chondrocytes

Di Chen, Huan Luo, Huan Yu, 2020, PloS one.

Vitamin C deficiency exacerbates diabetic glomerular injury through activation of transforming growth factor-β signaling.

W. Shi, Musaddique Hussain, Haibin Zhu, 2017, Biochimica et biophysica acta. General subjects.

α-Chaconine Facilitates Chondrocyte Pyroptosis and Nerve Ingrowth to Aggravate Osteoarthritis Progression by Activating NF-κB Signaling

Huihao Zhang, Huan Luo, Hongting Jin, 2022, Journal of inflammation research.

Direct Anterior Approach Provides Superior Prosthesis Adaptability in the Early Postoperative Period of Total Hip Arthroplasty

Jie Chen, Xiang Wang, Sai Yao, 2022, Orthopaedic surgery.

Col9a2 gene deletion accelerates the degeneration of intervertebral discs

Qinwen Ge, Hongting Jin, Pinger Wang, 2022, Experimental and therapeutic medicine.

Clinical Outcomes of Minimally Invasive Fixation with Pre‐Bent Elastic Stable Intramedullary Nails for the Treatment of Distal Radius Metaphyseal Diaphysis Junction Fractures in Children

Changzong Deng, Hongfeng Ruan, Limeng Yang, 2023, Orthopaedic surgery.