Chandramouli Chillakuri

发表

Notch receptor–ligand binding and activation: Insights from molecular studies

P. Handford, S. Lea, C. Chillakuri, 2012, Seminars in cell & developmental biology.

Therapeutic high affinity T cell receptor targeting a KRASG12D cancer neoantigen

J. Haidar, J. Dukes, M. W. van der Kamp, 2022, Nature Communications.

Mutations in Fibrillin-1 Cause Congenital Scleroderma: Stiff Skin Syndrome

D. Judge, P. Handford, D. Macaya, 2010, Science Translational Medicine.

C‐terminal truncated cannabinoid receptor 1 coexpressed with G protein trimer in Sf9 cells exists in a precoupled state and shows constitutive activity

H. Michel, C. Chillakuri, Christoph Reinhart, 2007, The FEBS journal.

The CD46 and Jagged1 interaction is critical for human T helper 1 immunity

P. Handford, M. Dallman, J. Köhl, 2012, Nature Immunology.

The CD 46-Jagged 1 interaction is critical for human TH 1 immunity

P. Handford, M. Dallman, J. Köhl, 2012 .

Fringe-mediated extension of O-linked fucose in the ligand-binding region of Notch1 increases binding to mammalian Notch ligands

P. Handford, S. Lea, C. Chillakuri, 2014, Proceedings of the National Academy of Sciences.

Heparin binding domain in vitronectin is required for oligomerization and thus enhances integrin mediated cell adhesion and spreading

C. Chillakuri, H. Mardon, Céline Jones, 2010, FEBS letters.

Structural Analysis Uncovers Lipid-Binding Properties of Notch Ligands

P. Handford, Raphael Kopan, S. Lea, 2013, Cell reports.

Development of Therapeutic Anti-JAGGED1 Antibodies for Cancer Therapy

A. Harris, A. Banham, P. Handford, 2019, Molecular Cancer Therapeutics.

Orientation and surface coverage of adsorbed fibronectin cell binding domains and bound integrin α5β1 receptors

Z. Li, C. Chillakuri, M. Kreiner, 2009 .

Structural and functional dissection of the interplay between lipid and Notch binding by human Notch ligands

P. Handford, S. Lea, C. Chillakuri, 2017, bioRxiv.