Dietmar Hoffmann

发表

PIM inhibitors target CD25-positive AML cells through concomitant suppression of STAT5 activation and degradation of MYC oncogene.

S. Gross, Q. Gao, D. Wiederschain, 2014, Blood.

suppression of STAT 5 activation and degradation of MYC oncogene PIM inhibitors target CD 25-positive AML cells through concomitant

S. Gross, Q. Gao, D. Wiederschain, 2014 .

Quantitative Proteomic Profiling Reveals Novel Plasmodium falciparum Surface Antigens and Possible Vaccine Candidates*

Eva Bric-Furlong, D. Wirth, M. Parrington, 2017, Molecular & Cellular Proteomics.

Selective Inhibition of Mutant Isocitrate Dehydrogenase 1 (IDH1) via Disruption of a Metal Binding Network by an Allosteric Small Molecule

Dietmar Hoffmann, Jean-Pierre Marquette, Magali Mathieu, 2014, The Journal of Biological Chemistry.

Glutaminase is essential for the growth of triple-negative breast cancer cells with a deregulated glutamine metabolism pathway and its suppression synergizes with mTOR inhibition

D. Wiederschain, C. Winter, J. Pollard, 2017, PloS one.

SAR439859, a Novel Selective Estrogen Receptor Degrader (SERD), Demonstrates Effective and Broad Antitumor Activity in Wild-Type and Mutant ER-Positive Breast Cancer Models

Joon Sang Lee, C. García-echeverría, L. Debussche, 2020, Molecular Cancer Therapeutics.

MOLECULAR CANCER THERAPEUTICS | SMALL MOLECULE THERAPEUTICS SAR439859, a Novel Selective Estrogen Receptor Degrader (SERD), Demonstrates Effective and Broad Antitumor Activity in Wild-Type and Mutant ER-Positive Breast Cancer Models

Joon Sang Lee, L. Debussche, M. Levit, 2020 .

The biosynthetic gene cluster of the maytansinoid antitumor agent ansamitocin from Actinosynnema pretiosum

L. Bai, S. Moss, E. Leistner, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Metal Binding Network by an Allosteric Dehydrogenase 1 ( IDH 1 ) via Disruption of Selective Inhibition of Mutant Isocitrate Enzymology

S. Gross, Q. Gao, D. Wiederschain, 2014 .

Honing-in antigen-specific cells during antibody discovery: a user-friendly process to mine a deeper repertoire

Sambasiva P Rao, Eva Bric-Furlong, Sagar V. Kathuria, 2022, Communications Biology.

Evaluation of Cancer Dependence and Druggability of PRP4 Kinase Using Cellular, Biochemical, and Structural Approaches

Q. Gao, D. Wiederschain, C. García-echeverría, 2013, The Journal of Biological Chemistry.

Biosynthesis of the ansamycin antibiotic rifamycin: deductions from the molecular analysis of the rif biosynthetic gene cluster of Amycolatopsis mediterranei S699.

C R Hutchinson, R. Müller, P. August, 1998, Chemistry & biology.

Occurrence and non-detectability of maytansinoids in individual plants of the genera Maytenus and Putterlickia.

E. Leistner, T. Mahmud, D. Hoffmann, 2003, Phytochemistry.

Identification of the endosomal sorting complex required for transport-I (ESCRT-I) as an important modulator of anti-miR uptake by cancer cells

Madelyn Light, Q. Gao, D. Wiederschain, 2014, Nucleic acids research.

A Biomedically Enriched Collection of 7000 Human ORF Clones

Yanhui Hu, Bernhard Korn, Dietmar Hoffmann, 2008, PloS one.

Oncogenic dependency on β-catenin in liver cancer cell lines correlates with pathway activation

D. Wiederschain, C. Winter, L. Schweizer, 2017, Oncotarget.

Bringing the Heavy Chain to Light: Creating a Symmetric, Bivalent IgG-Like Bispecific

Eva Bric-Furlong, Sagar V. Kathuria, Yanfeng Zhou, 2020, Antibodies.

Development of a physiologically relevant and easily scalable LUHMES cell-based model of G2019S LRRK2-driven Parkinson's disease

Barbara Calamini, D. Hoffmann, Pierrick Rival, 2021, Disease models & mechanisms.

High-Throughput and Format-Agnostic Mispairing Assay for Multispecific Antibodies Using Intact Mass Spectrometry.

N. Furtmann, D. Dimova, A. Brandenburg, 2023, Analytical chemistry.

Biosynthesis of 4-methylproline in cyanobacteria: cloning of nosE and nosF genes and biochemical characterization of the encoded dehydrogenase and reductase activities.

Richard E. Moore, J. Hevel, H. Luesch, 2003, The Journal of organic chemistry.