Kan Handa

Resetting the transcription factor network reverses terminal chronic hepatic failure.

K. Kaestner, Y. Vodovotz, A. Bell, 2015, The Journal of clinical investigation.

Regeneration and Cell Recruitment in an Improved Heterotopic Auxiliary Partial Liver Transplantation Model in the Rat

H. Yagi, A. Soto-Gutiérrez, M. Oertel, 2017, Transplantation.

Generation of Human Fatty Livers Using Custom-Engineered Induced Pluripotent Stem Cells with Modifiable SIRT1 Metabolism.

C. Deng, A. Soto-Gutiérrez, F. Weinberg, 2019, Cell metabolism.

Assembly and Function of a Bioengineered Human Liver for Transplantation Generated Solely from Induced Pluripotent Stem Cells.

H. Yagi, A. Duncan, A. Soto-Gutiérrez, 2020, Cell reports.

A switch in the source of ATP production and a loss in capacity to perform glycolysis are hallmarks of hepatocyte failure in advance liver disease.

Prahlad T. Ram, P. Ram, I. Pipinos, 2014, Journal of hepatology.

Assembly of human organs from stem cells to study liver disease.

A. Soto-Gutiérrez, K. Fukumitsu, K. Matsubara, 2014, The American journal of pathology.

Liver‐Regenerative Transplantation: Regrow and Reset

H. Yagi, K. Dorko, S. Presnell, 2016, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.