A. Segura

发表

Heterologous Hyperimmune Polyclonal Antibodies Against SARS-CoV-2: A Broad Coverage, Affordable, and Scalable Potential Immunotherapy for COVID-19

J. Gutiérrez, J. Drexler, M. Flores-Díaz, 2021, Frontiers in Medicine.

In Vitro Tests for Assessing the Neutralizing Ability of Snake Antivenoms: Toward the 3Rs Principles

J. Gutiérrez, G. Solano, M. Herrera, 2021, Frontiers in Immunology.

Comparative proteomic analysis of the venom of the taipan snake, Oxyuranus scutellatus, from Papua New Guinea and Australia: role of neurotoxic and procoagulant effects in venom toxicity.

David J. Williams, J. Calvete, J. Gutiérrez, 2012, Journal of proteomics.

Neutralization of the neuromuscular inhibition of venom and taipoxin from the taipan (Oxyuranus scutellatus) by F(ab')2 and whole IgG antivenoms.

David J. Williams, J. Gutiérrez, L. Rodrigues-Simioni, 2016, Toxicology letters.

Vipera berus berus Venom from Russia: Venomics, Bioactivities and Preclinical Assessment of Microgen Antivenom

J. Calvete, J. Gutiérrez, R. Al-Shekhadat, 2019, Toxins.

Pathogenic mechanisms underlying adverse reactions induced by intravenous administration of snake antivenoms.

J. Gutiérrez, M. Herrera, G. León, 2013, Toxicon : official journal of the International Society on Toxinology.

Intrageneric cross-reactivity of monospecific rabbit antisera against venoms of the medically most important Naja spp. African snakes

J. Gutiérrez, Aarón Gómez, M. Herrera, 2023, PLoS neglected tropical diseases.

Snake venomics of African spitting cobras: toxin composition and assessment of congeneric cross-reactivity of the pan-African EchiTAb-Plus-ICP antivenom by antivenomics and neutralization approaches.

J. Calvete, L. Sanz, J. Gutiérrez, 2011, Journal of proteome research.

Preclinical Evaluation of the Efficacy of Antivenoms for Snakebite Envenoming: State-of-the-Art and Challenges Ahead

J. Calvete, L. Sanz, J. Gutiérrez, 2017, Toxins.

Development and characterization of two equine formulations towards SARS-CoV-2 proteins for the potential treatment of COVID-19

J. Gutiérrez, Charles Bailey, Aarthi Narayanan, 2021, Scientific Reports.

Development and pre-clinical characterization of two therapeutic equine formulations towards SARS-CoV-2 proteins for the potential treatment of COVID-19

J. Gutiérrez, Charles Bailey, Aarthi Narayanan, 2020, bioRxiv.

Current technology for the industrial manufacture of snake antivenoms

J. Gutiérrez, G. Solano, Aarón Gómez, 2018, Toxicon : official journal of the International Society on Toxinology.

In vitro Characterization of Anti-SARS-CoV-2 Intravenous Immunoglobulins (IVIg) Produced From Plasma of Donors Immunized With the BNT162b2 Vaccine and Its Comparison With a Similar Formulation Produced From Plasma of COVID-19 Convalescent Donors

J. Drexler, A. Alape-Girón, Stephanie Chaves-Araya, 2022, Frontiers in Medical Technology.

Comparative venomics and preclinical efficacy evaluation of a monospecific Hemachatus antivenom towards sub-Saharan Africa cobra venoms.

J. Calvete, J. Gutiérrez, D. Pla, 2021, Journal of proteomics.

Comparison of adjuvant emulsions for their safety and ability to enhance the antibody response in horses immunized with African snake venoms

Cecilia Díaz, Mauricio Arguedas, Aarón Gómez, 2022, Vaccine: X.

Factors associated with adverse reactions induced by caprylic acid-fractionated whole IgG preparations: comparison between horse, sheep and camel IgGs.

J. Gutiérrez, B. Lomonte, J. Chippaux, 2005, Toxicon : official journal of the International Society on Toxinology.

Study of the design and analytical properties of the lethality neutralization assay used to estimate antivenom potency against Bothrops asper snake venom.

J. Gutiérrez, G. Solano, Aarón Gómez, 2010, Biologicals : journal of the International Association of Biological Standardization.

Assessment of snake antivenom purity by comparing physicochemical and immunochemical methods.

J. Gutiérrez, M. Herrera, G. León, 2013, Biologicals : journal of the International Association of Biological Standardization.

Pathogenesis of dermonecrosis induced by venom of the spitting cobra, Naja nigricollis: An experimental study in mice.

J. Gutiérrez, A. Arias, M. Herrera, 2016, Toxicon : official journal of the International Society on Toxinology.

Current Industrial Production of Snake Antivenoms

Mauricio Arguedas, Andrés Hernández, Andrés Sánchez, 2021 .

Development of a chicken-derived antivenom against the taipan snake (Oxyuranus scutellatus) venom and comparison with an equine antivenom.

David J. Williams, J. Gutiérrez, Aarón Gómez, 2016, Toxicon : official journal of the International Society on Toxinology.

Antivenomic characterization of two antivenoms against the venom of the taipan, Oxyuranus scutellatus, from Papua New Guinea and Australia.

David J. Williams, J. Gutiérrez, S. Serrano, 2014, The American journal of tropical medicine and hygiene.

Preclinical Evaluation of Caprylic Acid-Fractionated IgG Antivenom for the Treatment of Taipan (Oxyuranus scutellatus) Envenoming in Papua New Guinea

David J. Williams, J. Gutiérrez, S. Jensen, 2011, PLoS neglected tropical diseases.

Comparative study of the efficacy and safety of two polyvalent, caprylic acid fractionated [IgG and F(ab')2] antivenoms, in Bothrops asper bites in Colombia.

J. Gómez, J. Gutiérrez, Y. Angulo, 2012, Toxicon : official journal of the International Society on Toxinology.

Preclinical assessment of the efficacy of a new antivenom (EchiTAb-Plus-ICP) for the treatment of viper envenoming in sub-Saharan Africa.

J. Calvete, J. Gutiérrez, D. Warrell, 2010, Toxicon : official journal of the International Society on Toxinology.

Pathogenic mechanisms underlying adverse reactions induced by intravenous administration of snake antivenoms.

J. Gutiérrez, M. Herrera, G. León, 2013, Toxicon : official journal of the International Society on Toxinology.

Proteomic and toxinological characterization of the venom of the South African Ringhals cobra Hemachatus haemachatus.

J. Gutiérrez, B. Lomonte, M. Herrera, 2018, Journal of proteomics.

Antivenomic assessment of the immunological reactivity of EchiTAb-Plus-ICP, an antivenom for the treatment of snakebite envenoming in sub-Saharan Africa.

J. Calvete, L. Sanz, R. Harrison, 2010, The American journal of tropical medicine and hygiene.

High Efficacy of Therapeutic Equine Hyperimmune Antibodies Against SARS-CoV-2 Variants of Concern

J. Gutiérrez, C. Reusken, J. Drexler, 2021, bioRxiv.

Immune response towards snake venoms.

J. Gutiérrez, Andrés Hernández, M. Herrera, 2011, Inflammation & allergy drug targets.

Expanding the neutralization scope of the Central American antivenom (PoliVal-ICP) to include the venom of Crotalus durissus pifanorum.

J. Gutiérrez, Cecilia Díaz, Mauricio Arguedas, 2021, Journal of proteomics.

Snake venomics and antivenomics of Protobothrops mucrosquamatus and Viridovipera stejnegeri from Taiwan: keys to understand the variable immune response in horses.

J. Calvete, L. Sanz, J. Gutiérrez, 2012, Journal of proteomics.

Intrageneric cross-reactivity of monospecific rabbit antisera against venoms of mamba (Elapidae: Dendroaspis spp.) snakes

Aarón Gómez, M. Herrera, G. León, 2024, Toxicon: X.

Snake venomics of African spitting cobras: toxin composition and assessment of congeneric cross-reactivity of the pan-African EchiTAb-Plus-ICP antivenom by antivenomics and neutralization approaches.

J. Calvete, L. Sanz, J. Gutiérrez, 2011, Journal of proteome research.

Assessment of the impact of solvent/detergent treatment on the quality and potency of a whole IgG equine antivenom.

J. Gutiérrez, T. Burnouf, C. Su, 2009, Biologicals : journal of the International Association of Biological Standardization.

Pilot-scale evaluation of a dynamic body-feed filtration system for primary clarification of snake antivenoms produced by the caprylic acid method

Stephanie Chaves-Araya, G. Solano, M. Herrera, 2024, Toxicon: X.

Stability of equine IgG antivenoms obtained by caprylic acid precipitation: towards a liquid formulation stable at tropical room temperature.

J. Gutiérrez, G. Solano, M. Herrera, 2009, Toxicon : official journal of the International Society on Toxinology.

Purification of equine whole IgG snake antivenom by using an aqueous two phase system as a primary purification step.

J. Gutiérrez, M. Herrera, G. León, 2015, Biologicals : journal of the International Association of Biological Standardization.

Proteomic, toxicological and immunogenic characterization of Mexican west-coast rattlesnake (Crotalus basiliscus) venom and its immunological relatedness with the venom of Central American rattlesnake (Crotalus simus).

J. Gutiérrez, Aarón Gómez, M. Herrera, 2017, Journal of proteomics.