Mingxing Xie

Human and rodent carboxylesterases: immunorelatedness, overlapping substrate specificity, differential sensitivity to serine enzyme inhibitors, and tumor-related expression.

B. Yan, M. Xie, Lan Liu, 2002, Drug metabolism and disposition: the biological fate of chemicals.

The pregnane X receptor binds to response elements in a genomic context-dependent manner, and PXR activator rifampicin selectively alters the binding among target genes.

B. Yan, Xiulong Song, M. Xie, 2004, Drug metabolism and disposition: the biological fate of chemicals.

Design of tetrapeptide ligands as inhibitors of the Src SH2 domain.

K. Parang, N. Nam, R. Pitts, 2004, Bioorganic & medicinal chemistry.

DEC1 Negatively Regulates the Expression of DEC2 through Binding to the E-box in the Proximal Promoter*

Y. Wan, B. Yan, Xiulong Song, 2003, The Journal of Biological Chemistry.

Abundant expression of Dec1/stra13/sharp2 in colon carcinoma: its antagonizing role in serum deprivation-induced apoptosis and selective inhibition of procaspase activation.

Y. Wan, Shujun Ge, B. Yan, 2002, The Biochemical journal.

The expression of antiapoptotic protein survivin is transcriptionally upregulated by DEC1 primarily through multiple sp1 binding sites in the proximal promoter

Y. Li, R. Deng, B. Yan, 2006, Oncogene.

Mouse liver and kidney carboxylesterase (M-LK) rapidly hydrolyzes antitumor prodrug irinotecan and the N-terminal three quarter sequence determines substrate selectivity.

B. Yan, M. Xie, Dongfang Yang, 2003, Drug metabolism and disposition: the biological fate of chemicals.