Melchor Sánchez-Martínez

发表

The role of antibody responses against glycans in bioprosthetic heart valve calcification and deterioration

G. Gerosa, L. Iop, L. Badano, 2022, Nature Medicine.

An olive oil phenolic is a new chemotype of mutant isocitrate dehydrogenase 1 (IDH1) inhibitors

J. Lozano-Sánchez, A. Segura‐Carretero, S. Verdura, 2018, Carcinogenesis.

STAT3 labels a subpopulation of reactive astrocytes required for brain metastasis

R. Soffietti, J. Bosch-Barrera, J. Menéndez, 2018, Nature Medicine.

Metformin Is a Direct SIRT1-Activating Compound: Computational Modeling and Experimental Validation

J. Brunet, S. Verdura, E. Cuyás, 2018, Front. Endocrinol..

2-(Fluoromethoxy)-4′-(S-methanesulfonimidoyl)-1,1′-biphenyl (UCM-1306), an Orally Bioavailable Positive Allosteric Modulator of the Human Dopamine D1 Receptor for Parkinson’s Disease

J. Ballesteros, M. Loza, J. Brea, 2022, Journal of medicinal chemistry.

Novel Antagonist of the Type 2 Lysophosphatidic Acid Receptor (LPA2), UCM-14216, Ameliorates Spinal Cord Injury in Mice

Manisha Ray, M. López-Rodríguez, S. Ortega‐Gutiérrez, 2022, Journal of medicinal chemistry.

A novel agonist of the type 1 lysophosphatidic acid receptor (LPA1), UCM-05194, shows efficacy in neuropathic pain amelioration.

J. Chun, A. Ferrer-Montiel, R. Rivera, 2019, Journal of medicinal chemistry.

Metformin directly targets the H3K27me3 demethylase KDM6A/UTX

B. Viollet, S. Verdura, E. Cuyás, 2018, Aging cell.

Intrinsically disordered proteins as drug targets

M. Sánchez-Martínez, A. Nonell-Canals, Melchor Sánchez-Martínez, 2017 .

Computer-Aided Drug Design Applied to Marine Drug Discovery: Meridianins as Alzheimer’s Disease Therapeutic Agents

C. Ávila, M. Sánchez-Martínez, Laura Llorach-Parés, 2017, Marine drugs.

Meridianins and Lignarenone B as Potential GSK3β Inhibitors and Inductors of Structural Neuronal Plasticity

A. Giralt, J. Alberch, C. Ávila, 2020, Biomolecules.

Kororamides, Convolutamines, and Indole Derivatives as Possible Tau and Dual-Specificity Kinase Inhibitors for Alzheimer’s Disease: A Computational Study

C. Ávila, M. Sánchez-Martínez, Laura Llorach-Parés, 2018, Marine drugs.

Computer-Aided Drug Design (CADD) to De-Orphanize Marine Molecules: Finding Potential Therapeutic Agents for Neurodegenerative and Cardiovascular Diseases

C. Ávila, M. Sánchez-Martínez, Laura Llorach-Parés, 2022, Marine drugs.

Amyloid‐induced β‐cell dysfunction and islet inflammation are ameliorated by 4‐phenylbutyrate (PBA) treatment

M. Obach, Lisa Cadavez, A. Novials, 2017, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Mimetics of extra virgin olive oil phenols with anti-cancer stem cell activity

J. Lozano-Sánchez, A. Segura‐Carretero, S. Verdura, 2020, Aging.

Silibinin is a direct inhibitor of STAT3.

S. Verdura, E. Cuyás, J. Bosch-Barrera, 2018, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Protein disorder reduced in Saccharomyces cerevisiae to survive heat shock [version 1; peer review: 2 approved, 1 approved with reservations]

Esmeralda Vicedo, Tatyana Goldberg, Zofia Gasik, 2022 .

Computational de-orphanization of the olive oil biophenol oleacein: Discovery of new metabolic and epigenetic targets.

J. Lozano-Sánchez, A. Segura‐Carretero, J. Brunet, 2019, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Amyloid‐induced β‐cell dysfunction and islet inflammation are ameliorated by 4‐phenylbutyrate (PBA) treatment

M. Obach, Lisa Cadavez, A. Novials, 2017, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

The extra virgin olive oil phenolic oleacein is a dual substrate-inhibitor of catechol-O-methyltransferase.

J. Lozano-Sánchez, A. Segura‐Carretero, J. Encinar, 2019, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Enzymatic minimum free energy path calculations using swarms of trajectories.

Melchor Sanchez-Martinez, Ramon Crehuet, M. Field, 2015, The journal of physical chemistry. B.

Application of the maximum entropy principle to determine ensembles of intrinsically disordered proteins from residual dipolar couplings.

R. Crehuet, M. Sánchez-Martínez, M Sanchez-Martinez, 2014, Physical chemistry chemical physics : PCCP.

Conformational compression and barrier height heterogeneity in the N-acetylglutamate kinase.

M. Field, R. Tauler, E. Marcos, 2013, The journal of physical chemistry. B.

Extra-virgin olive oil contains a metabolo-epigenetic inhibitor of cancer stem cells

J. Lozano-Sánchez, A. Segura‐Carretero, S. Verdura, 2018, Carcinogenesis.