Brahim Achour

发表

Image analysis for individual identification and feeding behaviour monitoring of dairy cows based on Convolutional Neural Networks (CNN)

Malika Belkadi, Mourad Laghrouche, Idir Filali, 2020 .

Classification of dairy cows’ behavior by energy-efficient sensor

R. Aoudjit, Malika Belkadi, M. Daoui, 2021, Journal of Reliable Intelligent Environments.

Protein expression of various hepatic uridine 5′‐diphosphate glucuronosyltransferase (UGT) enzymes and their inter‐correlations: a meta‐analysis

A. Rostami-Hodjegan, B. Achour, J. Barber, 2014, Biopharmaceutics & drug disposition.

Mass Spectrometry of Human Transporters.

A. Rostami-Hodjegan, B. Achour, Zubida M. Al-Majdoub, 2020, Annual review of analytical chemistry.

Quantitative mass spectrometry-based proteomics in the era of model-informed drug development: Applications in translational pharmacology and recommendations for best practice.

Jill Barber, Amin Rostami-Hodjegan, Brahim Achour, 2019, Pharmacology & therapeutics.

Quantification of Proteins Involved in Intestinal Epithelial Handling of Xenobiotics

G. Warhurst, A. Rostami-Hodjegan, B. Achour, 2020, Clinical pharmacology and therapeutics.

Toward a Consensus on Applying Quantitative Liquid Chromatography‐Tandem Mass Spectrometry Proteomics in Translational Pharmacology Research: A White Paper

Jill Barber, Bhagwat Prasad, Amin Rostami-Hodjegan, 2019, Clinical pharmacology and therapeutics.

In Vitro–In Vivo Extrapolation Scaling Factors for Intestinal P-Glycoprotein and Breast Cancer Resistance Protein: Part I: A Cross-Laboratory Comparison of Transporter-Protein Abundances and Relative Expression Factors in Human Intestine and Caco-2 Cells

G. Warhurst, A. Rostami-Hodjegan, B. Achour, 2016, Drug Metabolism and Disposition.

Unsupervised automated monitoring of dairy cows' behavior based on Inertial Measurement Unit attached to their back

Rachida Aoudjit, Malika Belkadi, Brahim Achour, 2019, Comput. Electron. Agric..

Mass spectrometry‐based abundance atlas of ABC transporters in human liver, gut, kidney, brain and skin

N. Couto, A. Rostami-Hodjegan, B. Achour, 2020, FEBS letters.

High-accuracy and energy-efficient wearable device for dairy cows’ localization and activity detection using low-cost IMU/RFID sensors

R. Aoudjit, Idir Filali, Malika Belkadi, 2022, Microsystem Technologies.

Variability in Mass Spectrometry-based Quantification of Clinically Relevant Drug Transporters and Drug Metabolizing Enzymes.

J. Wiśniewski, P. Artursson, T. Andersson, 2017, Molecular pharmaceutics.

Translational value of liquid chromatography coupled with tandem mass spectrometry-based quantitative proteomics for in vitro–in vivo extrapolation of drug metabolism and transport and considerations in selecting appropriate techniques

A. Rostami-Hodjegan, B. Achour, Hajar Al Feteisi, 2015, Expert opinion on drug metabolism & toxicology.

Choice of LC-MS Methods for the Absolute Quantification of Drug-Metabolizing Enzymes and Transporters in Human Tissue: a Comparative Cost Analysis

A. Rostami-Hodjegan, B. Achour, Hajar Al Feteisi, 2015, The AAPS Journal.

Alternative fusion protein strategies to express recalcitrant QconCAT proteins for quantitative proteomics of human drug metabolizing enzymes and transporters.

A. Rostami-Hodjegan, B. Achour, M. Russell, 2013, Journal of proteome research.

Identification and quantification of blood–brain barrier transporters in isolated rat brain microvessels

A. Rostami-Hodjegan, B. Achour, Narciso Couto, 2018, Journal of neurochemistry.

Proteomic Quantification of Human Blood-Brain Barrier SLC and ABC Transporters in Healthy Individuals and Dementia Patients.

A. Rostami-Hodjegan, B. Achour, S. Neuhoff, 2019, Molecular pharmaceutics.

Proteomics of colorectal cancer liver metastasis: A quantitative focus on drug elimination and pharmacodynamics effects

S. Peters, A. Rostami-Hodjegan, B. Achour, 2021, British journal of clinical pharmacology.

Cytochrome P450 Pig Liver Pie: Determination of Individual Cytochrome P450 Isoform Contents in Microsomes from Two Pig Livers Using Liquid Chromatography in Conjunction with Mass Spectrometry

A. Rostami-Hodjegan, B. Achour, J. Barber, 2011, Drug Metabolism and Disposition.

Simultaneous Quantification of the Abundance of Several Cytochrome P450 and Uridine 5′-Diphospho-Glucuronosyltransferase Enzymes in Human Liver Microsomes Using Multiplexed Targeted Proteomics

A. Rostami-Hodjegan, B. Achour, M. Russell, 2014, Drug Metabolism and Disposition.

A family of QconCATs (Quantification conCATemers) for the quantification of human pharmacological target proteins.

A. Rostami-Hodjegan, B. Achour, Zubida M. Al-Majdoub, 2022, Journal of proteomics.

Quantitative Proteomics of Clinically Relevant Drug-Metabolizing Enzymes and Drug Transporters and Their Intercorrelations in the Human Small Intestine

Pamela J Davies, G. Warhurst, A. Rostami-Hodjegan, 2020, Drug Metabolism and Disposition.

Quantification of Proteins Involved in Drug Metabolism and Disposition in the Human Liver Using Label-Free Global Proteomics.

P. Wright, A. Rostami-Hodjegan, B. Achour, 2019, Molecular pharmaceutics.

Application of an LC-MS/MS method for the simultaneous quantification of human intestinal transporter proteins absolute abundance using a QconCAT technique.

G. Warhurst, A. Rostami-Hodjegan, B. Achour, 2015, Journal of pharmaceutical and biomedical analysis.

In Vitro–In Vivo Extrapolation Scaling Factors for Intestinal P-glycoprotein and Breast Cancer Resistance Protein: Part II. The Impact of Cross-Laboratory Variations of Intestinal Transporter Relative Expression Factors on Predicted Drug Disposition

Amin Rostami-Hodjegan, Gordon Carlson, Brahim Achour, 2016, Drug Metabolism and Disposition.

Proteomic quantification of receptor tyrosine kinases involved in the development and progression of colorectal cancer liver metastasis

A. Rostami-Hodjegan, B. Achour, Zubida M. Al-Majdoub, 2023, Frontiers in Oncology.

Liquid Biopsy for Patient Characterization in Cardiovascular Disease: Verification against Markers of Cytochrome P450 and P‐Glycoprotein Activities

Y. Daali, J. Reny, A. Rostami-Hodjegan, 2022, Clinical pharmacology and therapeutics.

Liquid Biopsy Enables Quantification of the Abundance and Interindividual Variability of Hepatic Enzymes and Transporters

K. Lea, J. Schageman, A. Rostami-Hodjegan, 2020, Clinical pharmacology and therapeutics.

Proteomic characterisation of drug metabolising enzymes and drug transporters in pig liver

A. Rostami-Hodjegan, B. Achour, Hajar Al Feteisi, 2020, Xenobiotica; the fate of foreign compounds in biological systems.

Cytochrome P450 Pig Liver Pie: Determination of Individual Cytochrome P450 Isoform Contents in Microsomes from Two Pig Livers Using Liquid Chromatography in Conjunction with Mass Spectrometry

A. Rostami-Hodjegan, J. Barber, Brahim Achour, 2011, Drug Metabolism And Disposition.

Variability in Mass Spectrometry-based Quantification of Clinically Relevant Drug Transporters and Drug Metabolizing Enzymes.

J. Wiśniewski, P. Artursson, H. Wortelboer, 2017, Molecular pharmaceutics.

Quantitative Proteomic Map of Enzymes and Transporters in the Human Kidney: Stepping Closer to Mechanistic Kidney Models to Define Local Kinetics

A. Galetin, A. Rostami-Hodjegan, B. Achour, 2021, Clinical pharmacology and therapeutics.

Review article: time to revisit Child‐Pugh score as the basis for predicting drug clearance in hepatic impairment

A. Rostami-Hodjegan, A. Darwich, B. Achour, 2021, Alimentary pharmacology & therapeutics.

Quantitative Characterization of Major Hepatic UDP-Glucuronosyltransferase Enzymes in Human Liver Microsomes: Comparison of Two Proteomic Methods and Correlation with Catalytic Activity

T. Goosen, A. Rostami-Hodjegan, J. Barber, 2017, Drug Metabolism and Disposition.

Quantitative Assessment of the Impact of Crohn's Disease on Protein Abundance of Human Intestinal Drug-Metabolising Enzymes and Transporters.

A. Rostami-Hodjegan, B. Achour, Zubida M. Al-Majdoub, 2022, Journal of pharmaceutical sciences.

Expression of Hepatic Drug-Metabolizing Cytochrome P450 Enzymes and Their Intercorrelations: A Meta-Analysis

A. Rostami-Hodjegan, J. Barber, Brahim Achour, 2014, Drug Metabolism and Disposition.

Hepatic Scaling Factors for In Vitro–In Vivo Extrapolation of Metabolic Drug Clearance in Patients with Colorectal Cancer with Liver Metastasis

S. Peters, A. Rostami-Hodjegan, B. Achour, 2021, Drug Metabolism and Disposition.

Hepatic Scaling Factors for In Vitro-In Vivo Extrapolation (IVIVE) of Metabolic Drug Clearance in Patients with Colorectal Cancer with Liver Metastasis

A. Rostami-Hodjegan, D. Scotcher, Areti-Maria Vasilogianni, 2021 .

Non-uniformity of Changes in Drug-Metabolizing Enzymes and Transporters in Liver Cirrhosis: Implications for Drug Dosage Adjustment

A. Rostami-Hodjegan, B. Achour, Zubida M. Al-Majdoub, 2021, Molecular pharmaceutics.

Novel Approaches to Characterize Individual Drug Metabolism and Advance Precision Medicine

Klarissa D Jackson, Jonghwa Lee, Jessica L. Beers, 2023, Drug Metabolism and Disposition.

Towards a test tube liver for drug metabolism studies

B. Achour, Brahim Achour, 2013 .

A. Rostami-Hodjegan, Hajar Al Feteisi, J. Barber, 2015, Expert opinion on drug metabolism & toxicology.

Scaling Factors for Clearance in Adult Liver Cirrhosis

A. Rostami-Hodjegan, B. Achour, V. Athwal, 2020, Drug Metabolism and Disposition.

Implications of intercorrelation between hepatic CYP3A4‐CYP2C8 enzymes for the evaluation of drug–drug interactions: a case study with repaglinide

J. Backman, A. Darwich, A. Rostami-Hodjegan, 2018, British journal of clinical pharmacology.

Quantitative Proteomics of Hepatic Drug‐Metabolizing Enzymes and Transporters in Patients With Colorectal Cancer Metastasis

A. Rostami-Hodjegan, B. Achour, Zubida M. Al-Majdoub, 2022, Clinical pharmacology and therapeutics.

Proteomic Quantification of Changes in Abundance of Drug-Metabolizing Enzymes and Drug Transporters in Human Liver Cirrhosis: Different Methods, Similar Outcomes

A. Rostami-Hodjegan, B. Achour, Zubida M. Al-Majdoub, 2021, Drug Metabolism and Disposition.

Ten years of QconCATs: Application of multiplexed quantification to small medically relevant proteomes

A. Rostami-Hodjegan, B. Achour, Zubida M. Al-Majdoub, 2015 .

Dealing With Variable Drug Exposure Due to Variable Hepatic Metabolism: A Proof-of-Concept Application of Liquid Biopsy in Renal Impairment.

A. Rostami-Hodjegan, K. Yee, Zubida M. Al-Majdoub, 2024, Clinical pharmacology and therapeutics.

Characterization of CYP2B6 K262R allelic variants by quantitative allele-specific proteomics using a QconCAT standard.

A. Rostami-Hodjegan, B. Achour, M. Russell, 2020, Journal of pharmaceutical and biomedical analysis.

In Vitro to In Vivo Scalars for Drug Clearance in Nonalcoholic Fatty Liver and Steatohepatitis

Brahim Achour, Teresa Sierra, 2024, Drug Metabolism and Disposition.

Global Proteomic Analysis of Human Liver Microsomes: Rapid Characterization and Quantification of Hepatic Drug-Metabolizing Enzymes

A. Rostami-Hodjegan, B. Achour, Francesco Lanucara, 2017, Drug Metabolism and Disposition.

GASP and FASP are Complementary for LC–MS/MS Proteomic Analysis of Drug‐Metabolizing Enzymes and Transporters in Pig Liver

A. Rostami-Hodjegan, B. Achour, Zubida M. Al-Majdoub, 2018, Proteomics.

Improved saccharification of Chlorella vulgaris biomass by fungal secreted enzymes for bioethanol production

G. Robson, J. Pittman, B. Achour, 2021 .

Data Generated by Quantitative Liquid Chromatography-Mass Spectrometry Proteomics Are Only the Start and Not the Endpoint: Optimization of Quantitative Concatemer-Based Measurement of Hepatic Uridine-5′-Diphosphate–Glucuronosyltransferase Enzymes with Reference to Catalytic Activity

T. Goosen, A. Rostami-Hodjegan, B. Achour, 2018, Drug Metabolism and Disposition.

Model-Informed Precision Dosing: Background, Requirements, Validation, Implementation, and Forward Trajectory of Individualizing Drug Therapy.

Y. Daali, J. Aronson, L. Lesko, 2020, Annual review of pharmacology and toxicology.