Aishwarya Prakash

发表

Supplemental Information for : Human Replication Protein A , Rad 52 , ssDNA Complex : Stoichiometry and Evidence for Strand Transfer Regulation by Phosphorylation †

G. Borgstahl, G. Oakley, K. Dhar, 2009 .

Destabilization of the PCNA trimer mediated by its interaction with the NEIL1 DNA glycosylase

S. Doublié, S. Wallace, A. Prakash, 2016, Nucleic acids research.

Characterization of long G4-rich enhancer-associated genomic regions engaging in a novel loop:loop ‘G4 Kissing’ interaction

Jingshan Huang, Glen M Borchert, Dominika Houserova, 2020, Nucleic acids research.

Phosphorylation Sites Identified in the NEIL1 DNA Glycosylase Are Potential Targets for the JNK1 Kinase

S. Doublié, A. Prakash, V. Cao, 2016, PloS one.

Mitochondrial DNA: Epigenetics and environment

Nidhi Sharma, A. Prakash, Monica S Pasala, 2019, Environmental and molecular mutagenesis.

Extracellular vesicles - mediating and delivering cardioprotection in acute myocardial infarction and heart failure.

S. Hernandez-Resendiz, D. Hausenloy, S. Ong, 2020, Conditioning medicine.

A. Prakash, M. Saki, Aishwarya Prakash, 2017, Free radical biology & medicine.

The Fpg/Nei family of DNA glycosylases: substrates, structures, and search for damage.

S. Doublié, S. Wallace, A. Prakash, 2012, Progress in molecular biology and translational science.

Novel interaction interfaces mediate the interaction between the NEIL1 DNA glycosylase and mitochondrial transcription factor A

P. Prevelige, S. Chakravarthy, A. Prakash, 2022, Frontiers in Cell and Developmental Biology.

The C-terminal tail of the NEIL1 DNA glycosylase interacts with the human mitochondrial single-stranded DNA binding protein.

Nidhi Sharma, S. Chakravarthy, W. Copeland, 2018, DNA repair.

Replication Protein A (RPA) Hampers the Processive Action of APOBEC3G Cytosine Deaminase on Single-Stranded DNA

G. Borgstahl, I. Rogozin, I. Waisertreiger, 2011, PloS one.

The Antitumor Drug LB-100 Is a Catalytic Inhibitor of Protein Phosphatase 2A (PPP2CA) and 5 (PPP5C) Coordinating with the Active-Site Catalytic Metals in PPP5C

R. Honkanen, M. Swingle, A. Prakash, 2019, Molecular Cancer Therapeutics.

Exploiting DNA Endonucleases to Advance Mechanisms of DNA Repair

R. Sobol, A. Prakash, Marlo K. Thompson, 2021, Biology.

Stabilization of a G-Quadruplex from Unfolding by Replication Protein A Using Potassium and the Porphyrin TMPyP4

G. Borgstahl, Fabien Kieken, L. Marky, 2011, Journal of nucleic acids.

PMS2 variant results in loss of ATPase activity without compromising mismatch repair

C. Deivanayagam, A. Prakash, Zhengrong Yang, 2022, Molecular genetics & genomic medicine.

Base Excision Repair in the Mitochondria

S. Doublié, A. Prakash, Aishwarya Prakash, 2015, Journal of cellular biochemistry.

Genome and cancer single nucleotide polymorphisms of the human NEIL1 DNA glycosylase: activity, structure, and the effect of editing.

S. Doublié, J. Sweasy, B. Carroll, 2014, DNA repair.

The changing landscape of Lynch syndrome due to PMS2 mutations

A. Prakash, J. Blount, Aishwarya Prakash, 2018, Clinical genetics.

Deciphering the orthorhombic crystal structure of a novel NEIL1 nanobody with pseudo-merohedral twinning

Marlo K. Thompson, Nidhi Sharma, Aishwarya Prakash, 2023, bioRxiv.

Stability and sub-cellular localization of DNA polymerase β is regulated by interactions with NQO1 and XRCC1 in response to oxidative stress

Robert, Nidhi Sharma, A. Wilk, 2019, Nucleic acids research.

Development of a Synthetic 3-ketosteroid Δ1-dehydrogenase for the Generation of a Novel Catabolic Pathway Enabling Cholesterol Degradation in Human Cells

L. Pannell, R. Honkanen, B. D'Arcy, 2019, Scientific Reports.

Polβ/XRCC1 heterodimerization dictates DNA damage recognition and basal Polβ protein levels without interfering with mouse viability or fertility.

C. Koczor, R. Sobol, A. Prakash, 2023, DNA repair.

Biochemical and structural characterization of two variants of uncertain significance in the PMS2 gene

A. Prakash, B. D’Arcy, J. Blount, 2019, Human mutation.

A Germline Polymorphism of Thymine DNA Glycosylase Induces Genomic Instability and Cellular Transformation

P. Sung, S. Doublié, J. Sweasy, 2014, PLoS genetics.

The NEIL1 G83D germline DNA glycosylase variant induces genomic instability and cellular transformation

C. Marsden, S. Doublié, J. Sweasy, 2017, Oncotarget.

Human Replication Protein A−Rad52−Single-Stranded DNA Complex: Stoichiometry and Evidence for Strand Transfer Regulation by Phosphorylation†

Carol Kolar, Gloria E. O. Borgstahl, Xiaoyi Deng, 2009, Biochemistry.

The structure and function of replication protein A in DNA replication.

G. Borgstahl, A. Prakash, Aishwarya Prakash, 2012, Sub-cellular biochemistry.

The Antitumor Drug LB-100 Is a Catalytic Inhibitor of Protein Phosphatase 2A (PPP2CA) and 5 (PPP5C) Coordinating with the Active-Site Catalytic Metals in PPP5C

R. Honkanen, M. Swingle, Kevin A. Abney, 2019, Molecular Cancer Therapeutics.

Deciphering the crystal structure of a novel nanobody against the NEIL1 DNA glycosylase.

Marlo K. Thompson, Nidhi Sharma, Aishwarya Prakash, 2024, Acta crystallographica. Section D, Structural biology.