Ralph R Reid

发表

Cloning and characterization of a gene cluster for geldanamycin production in Streptomyces hygroscopicus NRRL 3602.

Andreas Schirmer, Zhihao Hu, C Richard Hutchinson, 2003, FEMS microbiology letters.

A new enzyme superfamily - the phosphopantetheinyl transferases.

M. Marahiel, C. Walsh, C. Khosla, 1996, Chemistry & biology.

Subcutaneously Administered Self-Cleaving Hydrogel-Octreotide Conjugates Provide Very Long-Acting Octreotide.

R. Reid, D. Santi, G. Ashley, 2016, Bioconjugate chemistry.

Combinatorial polyketide biosynthesis by de novo design and rearrangement of modular polyketide synthase genes

John R Carney, Kedar G. Patel, R. Reid, 2005, Nature Biotechnology.

Long-term stabilization of maleimide-thiol conjugates.

Louise Robinson, R. Reid, D. Santi, 2015, Bioconjugate chemistry.

Redesign, synthesis and functional expression of the 6-deoxyerythronolide B polyketide synthase gene cluster

R. Reid, M. Welch, D. Santi, 2005, Journal of Industrial Microbiology and Biotechnology.

Total synthesis of long DNA sequences: synthesis of a contiguous 32-kb polyketide synthase gene cluster.

Sarah J Kodumal, Kedar G. Patel, R. Reid, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Hydrogel drug delivery system with predictable and tunable drug release and degradation rates

R. Reid, D. Santi, G. Ashley, 2013, Proceedings of the National Academy of Sciences.

Targeted covalent inactivation of protein kinases by resorcylic acid lactone polyketides.

R. Reid, D. Santi, J. Kennedy, 2006, Proceedings of the National Academy of Sciences of the United States of America.

A model of structure and catalysis for ketoreductase domains in modular polyketide synthases.

C Richard Hutchinson, R. Reid, D. Santi, 2003, Biochemistry.

A Very Long-acting Exatecan and Its Synergism with DNA Damage Response Inhibitors

R. Reid, G. Ashley, Shaun D. Fontaine, 2023, Cancer research communications.

Genes for the Biosynthesis of the Fungal Polyketides Hypothemycin from Hypomyces subiculosus and Radicicol from Pochonia chlamydosporia

R. Reid, J. Kealey, Zhihao Hu, 2008, Applied and Environmental Microbiology.

Molecular modeling and crystal structure of ERK2-hypothemycin complexes.

Giulio Rastelli, G. Rastelli, R. Rosenfeld, 2008, Journal of structural biology.

Insights into the Biosynthesis of the Benzoquinone Ansamycins Geldanamycin and Herbimycin, Obtained by Gene Sequencing and Disruption

C. Richard Hutchinson, Zhihao Hu, R. Reid, 2005, Applied and Environmental Microbiology.

A long-acting C-natriuretic peptide for achondroplasia

R. Reid, D. Santi, G. Ashley, 2022, Proceedings of the National Academy of Sciences of the United States of America.

A once-monthly GLP-1 receptor agonist for treatment of diabetic cats.

D. Santi, G. Ashley, D. Parkes, 2019, Domestic animal endocrinology.

Species-specific optimization of PEG~SN-38 prodrug pharmacokinetics and antitumor effects in a triple-negative BRCA1-deficient xenograft

B. Hann, R. Reid, D. Santi, 2019, Cancer Chemotherapy and Pharmacology.

Predictable and tunable half-life extension of therapeutic agents by controlled chemical release from macromolecular conjugates

R. Reid, D. Santi, G. Ashley, 2012, Proceedings of the National Academy of Sciences.

Exposition of a family of RNA m(5)C methyltransferases from searching genomic and proteomic sequences.

D. Santi, P. Greene, R. Reid, 1999, Nucleic acids research.

Analytical and Simulation-Based Models for Drug Release and Gel-Degradation in a Tetra-PEG Hydrogel Drug-Delivery System

A. Sali, M. Sgobba, G. Rastelli, 2015 .

GeMS: an advanced software package for designing synthetic genes

R. Reid, D. Santi, Sebastian Jayaraj, 2005, Nucleic acids research.

A very long-acting IL-15: implications for the immunotherapy of cancer

John A. Hangasky, T. Waldmann, R. Reid, 2022, Journal for ImmunoTherapy of Cancer.

The biosynthetic genes for disorazoles, potent cytotoxic compounds that disrupt microtubule formation.

R. Reid, H. Gramajo, N. Viswanathan, 2005, Gene.

Identification of new RNA modifying enzymes by iterative genome search using known modifying enzymes as probes.

D. Santi, C. Gustafsson, D V Santi, 1996, Nucleic acids research.

PLX038: a PEGylated prodrug of SN-38 independent of UGT1A1 activity

R. Reid, D. Santi, G. Ashley, 2019, Cancer Chemotherapy and Pharmacology.

Evolution in action.

T. Scanlan, Ralph R Reid, 1995, Chemistry & biology.

A Hydrogel-Microsphere Drug Delivery System That Supports Once-Monthly Administration of a GLP-1 Receptor Agonist.

S. Pfaff, N. Vrang, D. Santi, 2017, ACS chemical biology.

Approach for Half-Life Extension of Small Antibody Fragments That Does Not Affect Tissue Uptake.

S. Pfaff, R. Reid, D. Santi, 2016, Bioconjugate chemistry.

Hydrogel Drug Delivery System Using Self-Cleaving Covalent Linkers for Once-a-Week Administration of Exenatide.

R. Reid, D. Santi, G. Ashley, 2016, Bioconjugate chemistry.

A Controlled Release System for Long-Acting Intravitreal Delivery of Small Molecules

R. Reid, D. Santi, G. Ashley, 2018, Translational vision science & technology.

Analysis of the ambruticin and jerangolid gene clusters of Sorangium cellulosum reveals unusual mechanisms of polyketide biosynthesis.

R. Reid, C. Reeves, B. Julien, 2006, Chemistry & biology.